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R. Zaynagetdinov · SciRah

Researcher profile · Semantic Scholar

R. Zaynagetdinov

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R. Zaynagetdinov — researcher profile on SciRah

h-index: 22
Works: 57
Citations: 2,261

Most-cited papers

Adenosine receptors in regulation of dendritic cell differentiation and function.
S. Novitskiy, S. Ryzhov, R. Zaynagetdinov, Anna E. Goldstein +7 more
2008Blood424 citations Open access
Semantic Scholar
Identification of myeloid cell subsets in murine lungs using flow cytometry.
R. Zaynagetdinov, T. Sherrill, P. Kendall, B. Segal +3 more
2013American Journal of Respiratory Cell and Molecular Biology238 citations Open access
Semantic Scholar
Host A(2B) adenosine receptors promote carcinoma growth.
S. Ryzhov, S. Novitskiy, D. Carbone, I. Biaggioni +4 more
2008Neoplasia164 citations Open access
Semantic Scholar
Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease.
J. Kropski, Jason M. Pritchett, D. Zoz, Peter F. Crossno +30 more
2015American Journal of Respiratory and Critical Care Medicine149 citations Open access
Semantic Scholar
Effect of A2B Adenosine Receptor Gene Ablation on Adenosine-Dependent Regulation of Proinflammatory Cytokines
S. Ryzhov, R. Zaynagetdinov, Anna E. Goldstein, S. Novitskiy +3 more
2008Journal of Pharmacology and Experimental Therapeutics126 citations
Semantic Scholar
Interleukin-5 Facilitates Lung Metastasis by Modulating the Immune Microenvironment
R. Zaynagetdinov, T. Sherrill, L. Gleaves, A. McLoed +9 more
2015Cancer Research120 citations Open access
Semantic Scholar
Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease.
V. Polosukhin, Justin M. M. Cates, W. Lawson, R. Zaynagetdinov +9 more
2011American Journal of Respiratory and Critical Care Medicine119 citations Open access
Semantic Scholar
Neutrophil-derived IL-1β impairs efficacy of NF-κB inhibitors against lung cancer
A. McLoed, T. Sherrill, D. Cheng, W. Han +10 more
2016Cell Reports100 citations Open access
Semantic Scholar
Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome.
L. Young, Peter M. Gulleman, C. Short, H. Tanjore +8 more
2016JCI Insight97 citations Open access
Semantic Scholar
Effect of A2B Adenosine Receptor Gene Ablation on Proinflammatory Adenosine Signaling in Mast Cells1
S. Ryzhov, R. Zaynagetdinov, Anna E. Goldstein, S. Novitskiy +4 more
2008Journal of Immunology78 citations Open access
Semantic Scholar
Attenuation of chronic pulmonary inflammation in A2B adenosine receptor knockout mice.
R. Zaynagetdinov, S. Ryzhov, Anna E. Goldstein, Huiyong Yin +11 more
2010American Journal of Respiratory Cell and Molecular Biology63 citations Open access
Semantic Scholar
Chronic NF-κB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs
R. Zaynagetdinov, T. Sherrill, L. Gleaves, P. Hunt +7 more
2015OncoTarget60 citations Open access
Semantic Scholar
EPITHELIAL NUCLEAR FACTOR-κB SIGNALING PROMOTES LUNG CARCINOGENESIS VIA RECRUITMENT OF REGULATORY T LYMPHOCYTES
R. Zaynagetdinov, G. Stathopoulos, T. Sherrill, D. Cheng +10 more
2011Oncogene58 citations Open access
Semantic Scholar
Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization
E. Plosa, L. Young, Peter M. Gulleman, V. Polosukhin +10 more
2014Development48 citations Open access
Semantic Scholar
Molecular imaging of folate receptor β-positive macrophages during acute lung inflammation.
W. Han, R. Zaynagetdinov, F. Yull, V. Polosukhin +7 more
2014American Journal of Respiratory Cell and Molecular Biology46 citations Open access
Semantic Scholar
Identification and characterization of M6903, an antagonistic anti–TIM-3 monoclonal antibody
Dong Zhang, Feng Jiang, R. Zaynagetdinov, Hui-Rong Huang +15 more
2020Oncoimmunology39 citations Open access
Semantic Scholar
Epithelial-Derived Inflammation Disrupts Elastin Assembly and Alters Saccular Stage Lung Development.
J. Benjamin, Riet van der Meer, Amanda M. Im, E. Plosa +11 more
2016American Journal of Pathology39 citations Open access
Semantic Scholar
NF-κB-dependent airway inflammation triggers systemic insulin resistance.
T. J. Cyphert, R. T. Morris, Lawrence M. House, Tammy M. Barnes +7 more
2015American Journal of Physiology. Regulatory Integrative and Comparative Physiology39 citations Open access
Semantic Scholar
BMP Pathway Regulation of and by Macrophages
M. Talati, J. West, R. Zaynagetdinov, C. Hong +5 more
2014PLoS ONE31 citations Open access
Semantic Scholar
Allergic Airway Inflammation Decreases Lung Bacterial Burden following Acute Klebsiella pneumoniae Infection in a Neutrophil- and CCL8-Dependent Manner
D. Dulek, D. Newcomb, K. Goleniewska, J. Cephus +11 more
2014Infection and Immunity29 citations Open access
Semantic Scholar
Multifunctional NK Cell–Engaging Antibodies Targeting EGFR and NKp30 Elicit Efficient Tumor Cell Killing and Proinflammatory Cytokine Release
K. Klausz, Lukas Pekar, Ammelie Svea Boje, C. Gehlert +11 more
2022Journal of Immunology26 citations Open access
Semantic Scholar
Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers
Ammelie Svea Boje, Lukas Pekar, Katharina Koep, Britta Lipinski +12 more
2024mAbs22 citations Open access
Semantic Scholar
Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment
J. Saxon, T. Sherrill, V. Polosukhin, Jiqing Sai +11 more
2016Oncoimmunology22 citations Open access
Semantic Scholar
IKKβ Activity Drives Fetal Lung Macrophage Maturation Along a Non-M1/M2 Paradigm
Ashley N. Stouch, R. Zaynagetdinov, Whitney Barham, Amanda M Stinnett +5 more
2014Journal of Immunology21 citations Open access
Semantic Scholar
Opposing effects of bortezomib-induced nuclear factor-κB inhibition on chemical lung carcinogenesis.
Sophia P. Karabela, I. Psallidas, T. Sherrill, Chrysoula A. Kairi +13 more
2012Carcinogenesis18 citations Open access
Semantic Scholar
Dual A2A/ A2B adenosine receptor antagonist M1069 counteracts immuno-suppressive mechanisms of adenosine and reduces tumor growth in vivo.
K. Schiemann, Natalya Belousova, A. Matevossian, Kalyan C. Nallaparaju +15 more
2024Molecular Cancer Therapeutics16 citations
Semantic Scholar
Gas6/MerTK signaling is negatively regulated by NF-κB and supports lung carcinogenesis
S. Novitskiy, R. Zaynagetdinov, G. Vasiukov, S. Gutor +7 more
2019OncoTarget15 citations Open access
Semantic Scholar
Epithelial &bgr;1 integrin is required for lung branching morphogenesis and alveolarization
E. Plosa, L. Young, Peter M. Gulleman, V. Polosukhin +10 more
2015Journal of Cell Science15 citations
Semantic Scholar
Differential role of the carboxy-terminus of the A2B adenosine receptor in stimulation of adenylate cyclase, phospholipase Cβ, and interleukin-8
S. Ryzhov, R. Zaynagetdinov, Anna E. Goldstein, A. Matafonov +2 more
2009Purinergic Signalling Purinergic Signalling13 citations Open access
Semantic Scholar
A CRITICAL ROLE FOR MACROPHAGES IN PROMOTION OF URETHANE-INDUCED LUNG CARCINOGENESIS
R. Zaynagetdinov, T. Sherrill, V. Polosukhin, Weizhong Han +8 more
2011Journal of Immunology12 citations Open access
Semantic Scholar
Abstract 3499: M1069 as dual A2A/A2B adenosine receptor antagonist counteracts immune-suppressive mechanisms of adenosine and reduces tumor growth in vivo
R. Zaynagetdinov, K. Schiemann, Kalyan C. Nallaparaju, Natalya Belousova +13 more
2022Cancer Research5 citations
Semantic Scholar
NF-κB Activation Exacerbates, but Is not Required for Murine Bmpr2-Related Pulmonary Hypertension
M. Talati, H. Mutlak, K. Lane, W. Han +6 more
20145 citations Open access
Semantic Scholar
First-in-human study of the dual A2A/A2B adenosine receptor antagonist muvadenant (M1069) in patients with advanced solid tumors
L. Siu, M. Gutierrez, L. Pudelko, K. Ruth +7 more
2026ESMO Open2 citations Open access
Semantic Scholar
Adenosine A2B receptors in regulation of dendritic cell differentiation and function
S. Ryzhov, S. Novitskiy, R. Zaynagetdinov, Anna E. Goldstein +4 more
20082 citations
Semantic Scholar
Antibody framework engineering enables augmented cytokine receptor signaling capacities of bispecific single domain antibody-based IL-21 mimetics
Britta Lipinski, Laura Unmuth, Thi Hong Hue Tran, Jakob Harwood +12 more
2026mAbs1 citations Open access
Semantic Scholar
NF- (cid:2) B-dependent airway inﬂammation triggers systemic insulin resistance
T. J. Cyphert, R. T. Morris, Lawrence M. House, Tammy M. Barnes +7 more
20151 citations
Semantic Scholar
Abstract 2873: Epithelial NF-κB signaling is required for different functions in Kras- and EGFR-mediated lung tumorigenesis.
Jamie A. Ausborn, T. Sherrill, R. Zaynagetdinov, V. Polosukhin +3 more
20131 citations
Semantic Scholar
BRONCHIAL SECRETORY IgA DEFICIENCY CORRELATES WITH AIRWAY INFLAMMATION AND PROGRESSION OF COPD
V. Polosukhin, Justin M. M. Cates, W. Lawson, R. Zaynagetdinov +6 more
20111 citations
Semantic Scholar
Simultaneous targeting of IL-10 and PD-(L)1 pathways with a bispecific anti-PD-L1/IL-10-trap antibody enhances T cell responses
Latika Singh, Natalia Zabavnik, Sambasivan Venkatasubramanian, Sagi Barzilai +7 more
2026Molecular therapy. Oncology0 citations Open access
Semantic Scholar
Preclinical pharmacokinetics and biodistribution of the dual adenosine A2A/A2B inhibitor muvadenant (M1069) in rats.
Jonny Nachtigall, Christine K. Maurer, Marc Lecomte, K. Schiemann +3 more
2026Xenobiotica; the fate of foreign compounds in biological systems0 citations Open access
Semantic Scholar
Neutrophil-derived IL-1 β impairs efficacy of NF- κ B inhibitors against lung cancer
A. McLoed, T. Sherrill, D. Cheng, Wei Han +11 more
20160 citations
Semantic Scholar
Neutrophil-Derived IL-1 b I mpairs the Efficacy of NFk B Inhibitors against Lung Cancer Graphical
A. McLoed, T. Sherrill, D. Cheng, W. Han +10 more
20160 citations
Semantic Scholar
NF‐kappaB activation in the fetal lung promotes macrophage maturation (715.3)
Ashley N. Stouch, R. Zaynagetdinov, Whitney Barham, Amanda M Stinnett +4 more
20140 citations
Semantic Scholar
Running Title: Allergic inflammation decreases lung Klebsiella burden
D. Dulek, D. Newcomb, K. Goleniewska, J. Cephus +11 more
20140 citations
Semantic Scholar
Abstract 3667: Attenuation of NF-κB signaling in myeloid cells enhances urethane-induced lung tumorigenesis via neutrophil-derived IL-1β
A. McLoed, R. Zaynagetdinov, T. Sherrill, F. Yull +1 more
20140 citations
Semantic Scholar
Major Technical Advances Identiﬁcation of Myeloid Cell Subsets in Murine Lungs Using Flow Cytometry
R. Zaynagetdinov, T. Sherrill, P. Kendall, B. Segal +3 more
20130 citations
Semantic Scholar
Abstract 2875: NF-κB signaling in myeloid cells limits urethane-induced lung tumorigenesis.
A. McLoed, R. Zaynagetdinov, T. Sherrill, F. Yull +1 more
20130 citations
Semantic Scholar
Abstract 529: Impaired NF-κB signaling in myeloid cells enhances urethane-induced lung carcinogenesis
A. McLoed, R. Zaynagetdinov, T. Sherrill, F. Yull +1 more
20120 citations
Semantic Scholar
Abstract 2873: Opposing effects of NF-κB inhibition during chemical lung carcinogenesis
R. Zaynagetdinov, Sophia P. Karabela, I. Psallidas, T. Sherrill +11 more
20120 citations
Semantic Scholar
Abstract 313: K-ras- and EGFR-mediated lung tumor formation require epithelial NF-κB signaling to modulate the inflammatory microenvironment
Jamie A. Ausborn, T. Sherrill, R. Zaynagetdinov, V. Polosukhin +3 more
20120 citations
Semantic Scholar

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