Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

C. Zuurbier · SciRah

Researcher profile · Semantic Scholar

C. Zuurbier

Share profile

C. Zuurbier — researcher profile on SciRah

h-index: 53
Works: 189
Citations: 7,703

Most-cited papers

Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits
A. Baartscheer, C. Schumacher, R. Wüst, J. Fiolet +3 more
2016Diabetologia593 citations Open access
Semantic Scholar
Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation
L. Uthman, A. Baartscheer, Boris Bleijlevens, C. Schumacher +7 more
2017Diabetologia550 citations Open access
Semantic Scholar
Cardiac metabolism as a driver and therapeutic target of myocardial infarction
C. Zuurbier, L. Bertrand, C. Beauloye, I. Andreadou +11 more
2020Journal of Cellular and Molecular Medicine198 citations Open access
Semantic Scholar
Empagliflozin and Dapagliflozin Reduce ROS Generation and Restore NO Bioavailability in Tumor Necrosis Factor α-Stimulated Human Coronary Arterial Endothelial Cells.
L. Uthman, A. Homayr, R. Juni, Eva Spin +9 more
2019Cellular Physiology and Biochemistry186 citations Open access
Semantic Scholar
Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients
L. Uthman, A. Baartscheer, C. Schumacher, J. Fiolet +5 more
2018Frontiers in Physiology169 citations Open access
Semantic Scholar
Interaction of Cardiovascular Nonmodifiable Risk Factors, Comorbidities and Comedications With Ischemia/Reperfusion Injury and Cardioprotection by Pharmacological Treatments and Ischemic Conditioning
P. Ferdinandy, I. Andreadou, G. F. Baxter, H. Bøtker +9 more
2022Pharmacological Reviews150 citations Open access
Semantic Scholar
Direct cardiac effects of SGLT2 inhibitors
Sha Chen, R. Coronel, M. Hollmann, N. Weber +1 more
2022Cardiovascular Diabetology148 citations Open access
Semantic Scholar
Energy substrate metabolism and mitochondrial oxidative stress in cardiac ischemia/reperfusion injury.
M. Dambrova, C. Zuurbier, V. Borutaite, E. Liepinsh +1 more
2021Free Radical Biology & Medicine148 citations Open access
Semantic Scholar
Cardiac mechanisms of the beneficial effects of SGLT2 inhibitors in heart failure: Evidence for potential off-target effects.
J. Dyck, Samuel T. Sossalla, N. Hamdani, R. Coronel +3 more
2022Journal of Molecular and Cellular Cardiology136 citations Open access
Semantic Scholar
IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action
S. Lecour, I. Andreadou, H. Bøtker, Sean M. Davidson +6 more
2021Basic Research in Cardiology134 citations Open access
Semantic Scholar
Innate immunity as a target for acute cardioprotection.
C. Zuurbier, A. Abbate, H. Cabrera-Fuentes, M. Cohen +7 more
2019Cardiovascular Research131 citations Open access
Semantic Scholar
NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity
G. Stokman, L. Kors, P. J. Bakker, E. Rampanelli +11 more
2017Journal of Experimental Medicine110 citations Open access
Semantic Scholar
Empagliflozin reduces oxidative stress through inhibition of the novel inflammation/NHE/[Na+]c/ROS-pathway in human endothelial cells.
L. Uthman, Xiao-Ling Li, A. Baartscheer, C. Schumacher +7 more
2021Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie100 citations Open access
Semantic Scholar
Effect of hyperglycaemia and diabetes on acute myocardial ischaemia–reperfusion injury and cardioprotection by ischaemic conditioning protocols
C. Penna, I. Andreadou, M. Aragno, C. Beauloye +7 more
2020British Journal of Pharmacology97 citations Open access
Semantic Scholar
Delayed ischemic contracture onset by Empagliflozin associates with NHE-1 inhibition and is dependent on insulin in isolated mouse hearts.
L. Uthman, R. Nederlof, O. Eerbeek, A. Baartscheer +6 more
2019Cardiovascular Research83 citations Open access
Semantic Scholar
SGLT2 inhibitors reduce infarct size in reperfused ischemic heart and improve cardiac function during ischemic episodes in preclinical models.
I. Andreadou, R. Bell, H. Bøtker, C. Zuurbier
2020Biochimica et Biophysica Acta - Molecular Basis of Disease80 citations Open access
Semantic Scholar
Sodium Glucose Cotransporter-2 Inhibitor Empagliflozin Reduces Infarct Size Independently of Sodium Glucose Cotransporter-2.
Sha Chen, Qian Wang, Andriana Christodoulou, Nikolaos Mylonas +9 more
2023Circulation71 citations Open access
Semantic Scholar
Reduced acute myocardial ischemia–reperfusion injury in IL-6-deficient mice employing a closed-chest model
W. Jong, H. ten Cate, A. Linnenbank, O. D. de Boer +3 more
2016Inflammation Research70 citations Open access
Semantic Scholar
Novel Anti-inflammatory Effects of Canagliflozin Involving Hexokinase II in Lipopolysaccharide-Stimulated Human Coronary Artery Endothelial Cells
L. Uthman, Marius C. Kuschma, Gregor Römer, Marleen Boomsma +6 more
2020Cardiovascular Drugs and Therapy66 citations Open access
Semantic Scholar
Effect of metformin pretreatment on myocardial injury during coronary artery bypass surgery in patients without diabetes (MetCAB): a double-blind, randomised controlled trial.
S. El Messaoudi, R. Nederlof, C. Zuurbier, H. V. van Swieten +8 more
2015The Lancet Diabetes and Endocrinology66 citations
Semantic Scholar
Sodium Glucose Co-Transporter 2 Inhibitors Ameliorate Endothelium Barrier Dysfunction Induced by Cyclic Stretch through Inhibition of Reactive Oxygen Species
Xiao-Lin Li, Gregor Römer, Raphaela P. Kerindongo, J. Hermanides +5 more
2021International Journal of Molecular Sciences65 citations Open access
Semantic Scholar
Chronic Empagliflozin Treatment Reduces Myocardial Infarct Size in Nondiabetic Mice Through STAT-3-Mediated Protection on Microvascular Endothelial Cells and Reduction of Oxidative Stress
P. Nikolaou, P. Efentakis, Fairouz Abu Qourah, S. Femminò +15 more
2020Antioxidants and Redox Signaling65 citations Open access
Semantic Scholar
Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2
Sha Chen, Qian Wang, D. Bakker, Xin Hu +18 more
2024Basic Research in Cardiology60 citations Open access
Semantic Scholar
Cardioprotection by selective SGLT-2 inhibitors in a non-diabetic mouse model of myocardial ischemia/reperfusion injury: a class or a drug effect?
P. Nikolaou, Nikolaos Mylonas, M. Makridakis, M. Makrecka-Kuka +14 more
2022Basic Research in Cardiology56 citations Open access
Semantic Scholar
Cardiac intermediary metabolism in heart failure: substrate use, signalling roles and therapeutic targets
Mathias Mericskay, C. Zuurbier, L. Heather, A. Karlstaedt +6 more
2025Nature Reviews Cardiology55 citations Open access
Semantic Scholar
SGLT2 inhibitor empagliflozin inhibits the cardiac Na+/H+ exchanger 1: persistent inhibition under various experimental conditions.
C. Zuurbier, A. Baartscheer, C. Schumacher, J. Fiolet +1 more
2021Cardiovascular Research48 citations Open access
Semantic Scholar
Influence of cardiometabolic comorbidities on myocardial function, infarction, and CARDIOPROTECTION: Role of cardiac redox signaling.
I. Andreadou, A. Daiber, G. F. Baxter, M. Brizzi +7 more
2021Free Radical Biology & Medicine47 citations Open access
Semantic Scholar
Pharmacological Cardioprotection against Ischemia Reperfusion Injury—The Search for a Clinical Effective Therapy
Qian Wang, C. Zuurbier, R. Huhn, C. Torregroza +4 more
2023Cells46 citations Open access
Semantic Scholar
Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B
M. van Weeghel, D. Abdurrachim, R. Nederlof, Carmen Argmann +14 more
2018Cardiovascular Research44 citations Open access
Semantic Scholar
Amelioration of endothelial dysfunction by sodium glucose co‐transporter 2 inhibitors: pieces of the puzzle explaining their cardiovascular protection
Xiao-Lin Li, B. Preckel, J. Hermanides, M. Hollmann +2 more
2022British Journal of Pharmacology42 citations Open access
Semantic Scholar
Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium–glucose cotransporter 2 inhibitors
P. Wijnker, R. Dinani, Nico C. van der Laan, Sıla Algül +6 more
2024Cardiovascular Research40 citations Open access
Semantic Scholar
Increased in vivo mitochondrial oxygenation with right ventricular failure induced by pulmonary arterial hypertension: mitochondrial inhibition as driver of cardiac failure?
G. Balestra, E. Mik, O. Eerbeek, P. Specht +2 more
2015Respiratory Research40 citations Open access
Semantic Scholar
Empagliflozin prevents oxidative stress in human coronary artery endothelial cells via the NHE/PKC/NOX axis
Xiao-Ling Li, Meng-Nan Wang, Jan-Ole Kalina, B. Preckel +4 more
2023Redox Biology39 citations Open access
Semantic Scholar
Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome.
L. Kors, E. Rampanelli, G. Stokman, L. Butter +11 more
2018Biochimica et Biophysica Acta - Molecular Basis of Disease34 citations Open access
Semantic Scholar
Empagliflozin Decreases Lactate Generation in an NHE-1 Dependent Fashion and Increases α-Ketoglutarate Synthesis From Palmitate in Type II Diabetic Mouse Hearts
Hong Zhang, L. Uthman, Diane Bakker, Sahinda Sari +7 more
2020Frontiers in Cardiovascular Medicine31 citations Open access
Semantic Scholar
NLRP3 inflammasome in cardioprotective signaling.
C. Zuurbier
2019Journal of Cardiovascular Pharmacology31 citations Open access
Semantic Scholar
Reducing mitochondrial bound hexokinase II mediates transition from non-injurious into injurious ischemia/reperfusion of the intact heart
R. Nederlof, Ebru Gürel-Gurevin, O. Eerbeek, Chao-Qin Xie +10 more
2016Journal of physiology and biochemistry29 citations Open access
Semantic Scholar
In vivo mouse myocardial P-31 MRS using three-dimensional image-selected in vivo spectroscopy (3D ISIS): technical considerations and biochemical validations
A. Bakermans, D. Abdurrachim, B. J. Nierop, A. Koeman +9 more
201529 citations
Semantic Scholar
Empagliflozin in Acute Myocardial Infarction Reduces No-Reflow and Preserves Cardiac Function by Preventing Endothelial Damage
P. Nikolaou, L. Konijnenberg, I. Kostopoulos, M. Miliotis +24 more
2024JACC: Basic to Translational Science28 citations Open access
Semantic Scholar
NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart
Hong Zhang, Yang Xiao, R. Nederlof, Diane Bakker +8 more
2020Frontiers in Immunology26 citations Open access
Semantic Scholar
Effects of combined helium pre/post‐conditioning on the brain and heart in a rat resuscitation model
C. Aehling, N. Weber, C. Zuurbier, B. Preckel +5 more
2018Acta Anaesthesiologica Scandinavica25 citations Open access
Semantic Scholar
A randomized trial of remote ischemic preconditioning and control treatment for cardioprotection in sevoflurane-anesthetized CABG patients
R. Nederlof, N. Weber, N. Juffermans, B. D. de Mol +3 more
2017BMC Anesthesiology23 citations Open access
Semantic Scholar
Helium postconditioning regulates expression of caveolin-1 and -3 and induces RISK pathway activation after ischaemia/reperfusion in cardiac tissue of rats.
Moritz Flick, M. Albrecht, Gezina T. M. L. Oei, R. Steenstra +6 more
2016European Journal of Pharmacology21 citations
Semantic Scholar
Empagliflozin mitigates cardiac hypertrophy through cardiac RSK/NHE-1 inhibition.
Sha Chen, Kenneth Overberg, Z. Ghouse, M. Hollmann +3 more
2024Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie18 citations Open access
Semantic Scholar
Cardioprotective efficacy of limb remote ischaemic preconditioning in rats: discrepancy between a meta-analysis and a three-centre in vivo study
N. Sayour, G. Brenner, A. Makkos, B. Kiss +15 more
2023Cardiovascular Research17 citations Open access
Semantic Scholar
Canagliflozin inhibits inflammasome activation in diabetic endothelial cells - Revealing a novel calcium-dependent anti-inflammatory effect of canagliflozin on human diabetic endothelial cells.
Xiao-Lin Li, Raphaela P. Kerindongo, B. Preckel, Jan-Ole Kalina +3 more
2023Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie17 citations Open access
Semantic Scholar
NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy
Ye Liu, L. Kors, L. Butter, G. Stokman +6 more
2023Cells17 citations Open access
Semantic Scholar
Use of sodium-glucose cotransporter-2 inhibitors and the risk for sudden cardiac arrest and for all-cause death in patients with type 2 diabetes mellitus
T. Eroglu, R. Coronel, C. Zuurbier, M. Blom +2 more
2022European Heart Journal - Cardiovascular Pharmacotherapy17 citations Open access
Semantic Scholar
Effects of SGLT2 inhibitors on ion channels in heart failure: focus on the endothelium
Meng-Nan Wang, Benedikt Preckel, C. Zuurbier, Nina C. Weber
2025Basic Research in Cardiology16 citations Open access
Semantic Scholar
The Redox Modulating Sonlicromanol Active Metabolite KH176m and the Antioxidant MPG Protect Against Short-Duration Cardiac Ischemia-Reperfusion Injury
Yang Xiao, K. Yim, Hong Zhang, Diane Bakker +6 more
2021Cardiovascular Drugs and Therapy16 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

N. Weber×20
Invite
N. Weber — researcher profile on SciRah
M. Hollmann×17
Invite
M. Hollmann — researcher profile on SciRah
R. Coronel×11
Invite
R. Coronel — researcher profile on SciRah
B. Preckel×11
Invite
B. Preckel — researcher profile on SciRah

×8

Invite

A. Baartscheer — researcher profile on SciRah

C. Schumacher×8

Invite

C. Schumacher — researcher profile on SciRah

I. Andreadou×8

Invite

I. Andreadou — researcher profile on SciRah

Invite

R. Nederlof — researcher profile on SciRah

Invite

L. Uthman — researcher profile on SciRah

Invite

Sha Chen — researcher profile on SciRah

Invite

J. Fiolet — researcher profile on SciRah

M. Ruiz-Meana×4

Invite

M. Ruiz-Meana — researcher profile on SciRah