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A. Hautefeuille · SciRah

Researcher profile · Semantic Scholar

A. Hautefeuille

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A. Hautefeuille — researcher profile on SciRah

h-index: 32
Works: 63
Citations: 2,882

Most-cited papers

Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems.
H. Bartsch, C. Malaveille, A. Camus, Ghislaine Martel-Planche +8 more
1980Mutation research244 citations
Semantic Scholar
Genetic polymorphisms of MPO, COMT, MnSOD, NQO1, interactions with environmental exposures and bladder cancer risk.
R. Hung, P. Boffetta, P. Brennan, C. Malaveille +5 more
2004Carcinogenesis206 citations
Semantic Scholar
GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high‐risk population
R. Hung, P. Boffetta, P. Brennan, C. Malaveille +8 more
2004International Journal of Cancer199 citations Open access
Semantic Scholar
Polymorphisms of the DNA repair genes XRCC1, XRCC3, XPD, interaction with environmental exposures, and bladder cancer risk in a case-control study in northern Italy.
Min Shen, R. Hung, P. Brennan, C. Malaveille +6 more
2003Cancer Epidemiology, Biomarkers and Prevention161 citations
Semantic Scholar
Skin human papillomavirus type 38 alters p53 functions by accumulation of ΔNp73
R. Accardi, W. Dong, A. Smet, Rutao Cui +6 more
2006105 citations Open access
Semantic Scholar
Properties of the six isoforms of p63: p53-like regulation in response to genotoxic stress and cross talk with DeltaNp73.
A. Petitjean, C. Ruptier, V. Tribollet, A. Hautefeuille +5 more
2008Carcinogenesis101 citations
Semantic Scholar
White blood cell DNA adducts and fruit and vegetable consumption in bladder cancer.
M. Peluso, L. Airoldi, C. Magagnotti, L. Fiorini +4 more
2000Carcinogenesis95 citations Open access
Semantic Scholar
32P Postlabelling analysis of urinary mutagens from smokers of black tobacco implicates 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) as a major DNA-damaging agent.
M. Peluso, M. Castegnaro, C. Malaveille, M. Friesen +5 more
1991Carcinogenesis91 citations
Semantic Scholar
Formation of direct-acting genotoxic substances in nitrosated smoked fish and meat products: identification of simple phenolic precursors and phenyldiazonium ions as reactive products.
H. Ohshima, M. Friesen, C. Malaveille, I. Brouet +2 more
1989Food and Chemical Toxicology90 citations
Semantic Scholar
Skin human papillomavirus type 38 alters p53 functions by accumulation of deltaNp73.
R. Accardi, W. Dong, A. Smet, Rutao Cui +6 more
2006EMBO Reports80 citations
Semantic Scholar
p53 regulates the transcription of its Δ133p53 isoform through specific response elements contained within the TP53 P2 internal promoter
V. Marcel, V. Vijayakumar, L. Fernandez-Cuesta, H. Hafsi +4 more
2010Oncogene75 citations
Semantic Scholar
Dietary phenolics as anti-mutagens and inhibitors of tobacco-related DNA adduction in the urothelium of smokers.
C. Malaveille, A. Hautefeuille, B. Pignatelli, G. Talaska +2 more
1996Carcinogenesis74 citations
Semantic Scholar
Genetic polymorphism of N-acetyltransferases, glutathione S-transferase M1 and NAD(P)H:quinone oxidoreductase in relation to malignant and benign pancreatic disease risk
H. Bartsch, C. Malaveille, A. Lowenfels, P. Maisonneuve +2 more
1998European Journal of Cancer Prevention71 citations
Semantic Scholar
Levels of mutagens in the urine of smokers of black and blond tobacco correlate with their risk of bladder cancer.
C. Malaveille, P. Vineis, J. Estève, H. Ohshima +6 more
1989Carcinogenesis70 citations
Semantic Scholar
PRIMA-1, a mutant p53 reactivator, induces apoptosis and enhances chemotherapeutic cytotoxicity in pancreatic cancer cell lines
P. Izetti, A. Hautefeuille, A. Abujamra, C. B. de Farias +8 more
2014Investigational new drugs67 citations
Semantic Scholar
Mutagens produced by the pyrolysis of opium and its alkaloids as possible risk factors in cancer of the bladder and oesophagus.
C. Malaveille, M. Friesen, A. Camus, L. Garren +5 more
1982Carcinogenesis66 citations
Semantic Scholar
Effects of the TP53 p.R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: interaction with hepatitis B virus X protein.
Doriane A Gouas, Hong Shi, A. Hautefeuille, S. Ortiz-Cuàran +10 more
2010Carcinogenesis64 citations Open access
Semantic Scholar
Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-kappaB
V. Benoit, E. de Moraes, N. Dar, E. Taranchon +8 more
2006Oncogene63 citations Open access
Semantic Scholar
Interactions between genetic polymorphism of cytochrome P450‐1B1, sulfotransferase 1A1, catechol‐o‐methyltransferase and tobacco exposure in breast cancer risk
M. Saintot, C. Malaveille, A. Hautefeuille, M. Gerber
2003International Journal of Cancer62 citations
Semantic Scholar
Determinants of 4-aminobiphenyl-DNA adducts in bladder cancer biopsies.
L. Airoldi, F. Orsi, C. Magagnotti, R. Coda +6 more
2002Carcinogenesis60 citations
Semantic Scholar
Lack of mutagenicity of synthetic pyrethroids in Salmonella typhimurium strains and in V79 Chinese hamster cells.
Mathieu Pluijmen, C. Drevon, R. Montesano, C. Malaveille +2 more
1984Mutation research60 citations
Semantic Scholar
Characterization and identification of 6 mutagens in opium pyrolysates implicated in oesophagel cancer in Iran
M. Friesen, I. O'neill, C. Malaveille, L. Garren +10 more
198559 citations
Semantic Scholar
Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture.
S. Roman, A. Pétré, A. Thépot, A. Hautefeuille +3 more
2007American Journal of Physiology - Gastrointestinal and Liver Physiology55 citations
Semantic Scholar
CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: effects on motility, migration and p63 expression.
A. Krais, A. Hautefeuille, M. Cros, V. Krutovskikh +8 more
2011Carcinogenesis53 citations Open access
Semantic Scholar
Identification, occurrence and mutagenicity in Salmonella typhimurium of two synthetic nitroarenes, musk ambrette and musk xylene, in Indian chewing tobacco and betel quid.
Jagadeesan Nair, H. Ohshima, C. Malaveille, M. Friesen +3 more
1986Food and Chemical Toxicology48 citations
Semantic Scholar
Some factors determining the concentration of liver proteins for optimal mutagenicity of chemicals in the Salmonella/microsome assay.
C. Malaveille, T. Kuroki, Giséle Brun, A. Hautefeuille +2 more
1979Mutation research45 citations
Semantic Scholar
Mutagens, N-nitroso compounds and their precursors in gastric juice from patients with and without precancerous lesions of the stomach.
B. Pignatelli, C. Malaveille, A. Rogatko, A. Hautefeuille +6 more
1993European Journal of Cancer39 citations
Semantic Scholar
Interactions between hepatitis B virus and aflatoxin B(1): effects on p53 induction in HepaRG cells.
Myriam Lereau, Doriane A Gouas, Stephanie Villar, A. Besaratinia +9 more
2012Journal of General Virology36 citations Open access
Semantic Scholar
In vitro and in vivo cytotoxic effects of PRIMA-1 on hepatocellular carcinoma cells expressing mutant p53ser249.
Hong Shi, J. Lambert, A. Hautefeuille, V. J. Bykov +3 more
2008Carcinogenesis36 citations
Semantic Scholar
4‐aminobiphenyl‐DNA adducts and p53 mutations in bladder cancer
T. Martone, L. Airoldi, C. Magagnotti, R. Coda +6 more
1998International Journal of Cancer35 citations Open access
Semantic Scholar
Characterization and identification of 6 mutagens in opium pyrolysates implicated in oesophageal cancer in Iran.
M. Friesen, I. O'neill, C. Malaveille, L. Garren +6 more
1985Mutation research34 citations
Semantic Scholar
Levels of direct-acting mutagens, total N-nitroso compounds in nitrosated fermented fish products, consumed in a high-risk area for gastric cancer in southern China.
C. Chen, B. Pignatelli, C. Malaveille, G. Bouvier +4 more
1992Mutation research32 citations
Semantic Scholar
Antimutagenic dietary phenolics as antigenotoxic substances in urothelium of smokers.
C. Malaveille, A. Hautefeuille, Brigitte Pignatelli, Glenn Talaska +2 more
1998Mutation research31 citations
Semantic Scholar
Transcriptional regulation of thymine DNA glycosylase (TDG) by the tumor suppressor protein p53
N. M. Da Costa, A. Hautefeuille, M. Cros, M. Melendez +4 more
2012Cell Cycle30 citations Open access
Semantic Scholar
Bacterial and mammalian mutagenicity tests: validation and comparative studies on 180 chemicals.
H. Bartsch, C. Malaveille, A. Camus, Ghislaine Martel-Planche +8 more
1980IARC scientific publications30 citations
Semantic Scholar
Intraepithelial p63‐dependent expression of distinct components of cell adhesion complexes in normal esophageal mucosa and squamous cell carcinoma
A. Thépot, A. Hautefeuille, M. Cros, B. Abedi-Ardekani +4 more
2010International Journal of Cancer26 citations
Semantic Scholar
Substituted hydroxyphenanthrenes in opium pyrolysates implicated in oesophageal cancer in Iran: structures and in vitro metabolic activation of a novel class of mutagens.
M. Friesen, Ian K. O'Neill, C. Malaveille, L. Garren +2 more
1987Carcinogenesis23 citations
Semantic Scholar
Interaction between genetic polymorphism of cytochrome P450-1B1 and environmental pollutants in breast cancer risk
M. Saintot, C. Malaveille, A. Hautefeuille, M. Gerber
2004European Journal of Cancer Prevention22 citations
Semantic Scholar
Characterisation of human fibroblasts as keratinocyte feeder layer using p63 isoforms status
C. Auxenfans, A. Thépot, V. Justin, A. Hautefeuille +3 more
2009Bio-medical materials and engineering19 citations
Semantic Scholar
Effect of glutathione and uridine 5'-diphosphoglucuronic acid on mutagenesis by benzo[a]pyrene and aflatoxin B1 in the Salmonella/microsome assay.
C. Malaveille, G. Brun, A. Hautefeuille, H. Bartsch
1981Mutation research16 citations
Semantic Scholar
Substances in human urine that strongly inhibit bacterial mutagenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and related heterocyclic amines.
C. Malaveille, A. Hautefeuille, G. Brun, P. Vineis +1 more
1992Carcinogenesis14 citations
Semantic Scholar
Randomized controlled trial of dietary intervention: association between level of urinary phenolics and anti-mutagenicity.
C. Malaveille, L. Fiorini, Monica Bianchini, L. Davico +5 more
2004Mutation research12 citations
Semantic Scholar
Synthesis, structure-activity relationships and a reaction mechanism for mutagenic N-nitroso derivatives of glycosylamines and Amadori compounds--model substances for N-nitrosated early Maillard reaction products.
B. Pignatelli, C. Malaveille, M. Friesen, A. Hautefeuille +3 more
1987Food and Chemical Toxicology11 citations
Semantic Scholar
Liver microsome-mediated mutagenicity of dihydrodiols derived from dibenz(a,c)anthracene in S. typhimurium TA100.
C. Malaveille, A. Hautefeuille, H. Bartsch, A. Macnicoll +2 more
1980Carcinogenesis11 citations
Semantic Scholar
CHRNA 5 as negative regulator of nicotine signaling in normal and cancer bronchial cells : effects on motility , migration and p 63 expression
A. Krais, A. Hautefeuille, Marie-Pierre, Cros +9 more
20119 citations
Semantic Scholar
In vitro and in vivo cytotoxic effects of PRIMA-1 on hepatocellular carcinoma cells expressing mutant p 53 ser 249
Hong Shi, J. Lambert, A. Hautefeuille, V. J. Bykov +3 more
20089 citations
Semantic Scholar
Interrelationships in mice of antipyrine half-life, hepatic monooxygenase activities and liver S9-mediated mutagenicity of aflatoxin B1, benzo[alpha]pyrene 7,8-dihydrodiol, 2-acetylaminofluorene and N-nitrosomorpholine.
M. Roberfroid, C. Malaveille, A. Hautefeuille, G. Brun +2 more
1983Chemico-Biological Interactions8 citations
Semantic Scholar
Identification of a second promoter in the human c-ets-2 proto-oncogene.
Agnès Bègue, P. Crépieux, N. Vu‐Dac, A. Hautefeuille +3 more
1997Gene Expression6 citations
Semantic Scholar
Improved Methods for Analysis ofN-Nitroso Compounds and Applications in Human Biomonitoring
B. Pignatelli, C. Malaveille, P. Thuillier, A. Hautefeuille +1 more
19946 citations
Semantic Scholar
Effect of glutathione and uridine 5'-diphosphoglucuronic acid on benzo(a)pyrene mutagenesis in the Salmonella/microsome assay.
C. Malaveille, G. Brun, A. Hautefeuille, H. Bartsch
1980Developments in toxicology and environmental science6 citations
Semantic Scholar

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