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T. Akashi · SciRah

Researcher profile · Semantic Scholar

T. Akashi

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T. Akashi — researcher profile on SciRah

h-index: 27
Works: 67
Citations: 3,022

Most-cited papers

Licorice β-amyrin 11-oxidase, a cytochrome P450 with a key role in the biosynthesis of the triterpene sweetener glycyrrhizin
H. Seki, K. Ohyama, Satoru Sawai, M. Mizutani +6 more
2008Proceedings of the National Academy of Sciences of the United States of America396 citations Open access
Semantic Scholar
Triterpene Functional Genomics in Licorice for Identification of CYP72A154 Involved in the Biosynthesis of Glycyrrhizin[C][W][OA]
H. Seki, Satoru Sawai, K. Ohyama, M. Mizutani +7 more
2011The Plant Cell312 citations Open access
Semantic Scholar
Flavonoids of Leguminous Plants: Structure, Biological Activity, and Biosynthesis
T. Aoki, T. Akashi, S. Ayabe
2000Journal of plant research241 citations
Semantic Scholar
Cloning and functional expression of a cytochrome P450 cDNA encoding 2-hydroxyisoflavanone synthase involved in biosynthesis of the isoflavonoid skeleton in licorice.
T. Akashi, T. Aoki, S. Ayabe
1999Plant Physiology201 citations Open access
Semantic Scholar
Cytochrome P450s in flavonoid metabolism
S. Ayabe, T. Akashi
2006Phytochemistry Reviews118 citations
Semantic Scholar
Molecular and Biochemical Characterization of 2-Hydroxyisoflavanone Dehydratase. Involvement of Carboxylesterase-Like Proteins in Leguminous Isoflavone Biosynthesis1[w]
T. Akashi, T. Aoki, S. Ayabe
2005Plant Physiology114 citations Open access
Semantic Scholar
Induction of isoflavonoid pathway in the model legume Lotus japonicus: molecular characterization of enzymes involved in phytoalexin biosynthesis.
N. Shimada, T. Akashi, T. Aoki, S. Ayabe
2000Plant Science111 citations
Semantic Scholar
Identification of a cytochrome P450 cDNA encoding (2S)‐flavanone 2‐hydroxylase of licorice (Glycyrrhiza echinata L.; Fabaceae) which represents licodione synthase and flavone synthase II 1
T. Akashi, T. Aoki, S. Ayabe
1998FEBS Letters106 citations Open access
Semantic Scholar
Molecular Cloning and Characterization of a cDNA for Pterocarpan 4-Dimethylallyltransferase Catalyzing the Key Prenylation Step in the Biosynthesis of Glyceollin, a Soybean Phytoalexin1[W]
T. Akashi, Kanako Sasaki, T. Aoki, S. Ayabe +1 more
2008Plant Physiology105 citations Open access
Semantic Scholar
CYP81E1, a cytochrome P450 cDNA of licorice (Glycyrrhiza echinata L.), encodes isoflavone 2'-hydroxylase.
T. Akashi, T. Aoki, S. Ayabe
1998Biochemical and Biophysical Research Communications - BBRC96 citations
Semantic Scholar
Molecular cloning and biochemical characterization of a novel cytochrome P450, flavone synthase II, that catalyzes direct conversion of flavanones to flavones.
T. Akashi, M. Fukuchi-Mizutani, T. Aoki, Y. Ueyama +4 more
1999Plant and Cell Physiology84 citations Open access
Semantic Scholar
cDNA cloning and biochemical characterization of S-adenosyl-L-methionine: 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase, a critical enzyme of the legume isoflavonoid phytoalexin pathway.
T. Akashi, Yuji Sawada, N. Shimada, N. Sakurai +2 more
2003Plant and Cell Physiology82 citations Open access
Semantic Scholar
Key amino acid residues required for aryl migration catalysed by the cytochrome P450 2-hydroxyisoflavanone synthase.
Yuji Sawada, K. Kinoshita, T. Akashi, T. Aoki +1 more
2002The Plant Journal74 citations Open access
Semantic Scholar
Biosynthesis of triterpenoids in cultured cells, and regenerated and wild plant organs of Taraxacum officinale
T. Akashi, T. Furuno, Takeyoshi Takahashi, S. Ayabe
199472 citations
Semantic Scholar
Plant lanosterol synthase: divergence of the sterol and triterpene biosynthetic pathways in eukaryotes.
Satoru Sawai, T. Akashi, N. Sakurai, Hideyuki Suzuki +3 more
2006Plant and Cell Physiology69 citations Open access
Semantic Scholar
The Missing Link in Leguminous Pterocarpan Biosynthesis is a Dirigent Domain-Containing Protein with Isoflavanol Dehydratase Activity
Kai Uchida, T. Akashi, T. Aoki
2017Plant and Cell Physiology68 citations Open access
Semantic Scholar
2-Hydroxyisoflavanone dehydratase is a critical determinant of isoflavone productivity in hairy root cultures of Lotus japonicus.
M. Shimamura, T. Akashi, N. Sakurai, Hideyuki Suzuki +4 more
2007Plant and Cell Physiology64 citations
Semantic Scholar
Identification of cDNAs encoding pterocarpan reductase involved in isoflavan phytoalexin biosynthesis in Lotus japonicus by EST mining
T. Akashi, Shoko Koshimizu, T. Aoki, S. Ayabe
2006FEBS Letters53 citations
Semantic Scholar
Identification of protein-protein interactions of isoflavonoid biosynthetic enzymes with 2-hydroxyisoflavanone synthase in soybean (Glycine max (L.) Merr.).
Toshiyuki Waki, DongChan Yoo, N. Fujino, R. Mameda +8 more
2016Biochemical and Biophysical Research Communications - BBRC50 citations
Semantic Scholar
Induction of isoflavonoid and retrochalcone branches of the flavonoid pathway in cultured Glycyrrhiza echinata cells treated with yeast extract.
Kazuhiko Nakamura, T. Akashi, T. Aoki, K. Kawaguchi +1 more
1999Bioscience, biotechnology and biochemistry49 citations
Semantic Scholar
Molecular Characterization of Soybean Pterocarpan 2-Dimethylallyltransferase in Glyceollin Biosynthesis: Local Gene and Whole-Genome Duplications of Prenyltransferase Genes Led to the Structural Diversity of Soybean Prenylated Isoflavonoids
K. Yoneyama, T. Akashi, T. Aoki
2016Plant and Cell Physiology46 citations Open access
Semantic Scholar
Genome-wide Analyses of the Structural Gene Families Involved in the Legume-specific 5-Deoxyisoflavonoid Biosynthesis of Lotus japonicus
N. Shimada, Shusei Sato, T. Akashi, Yasukazu Nakamura +3 more
2007DNA Research43 citations Open access
Semantic Scholar
Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters.
S. Oguro, T. Akashi, S. Ayabe, H. Noguchi +1 more
2004Biochemical and Biophysical Research Communications - BBRC42 citations
Semantic Scholar
Planteose as a storage carbohydrate required for early stage of germination of Orobanche minor and its metabolism as a possible target for selective control
T. Wakabayashi, B. Joseph, Shuhei Yasumoto, T. Akashi +10 more
2015Journal of Experimental Botany41 citations Open access
Semantic Scholar
Molecular characterization of an oxidosqualene cyclase that yields shionone, a unique tetracyclic triterpene ketone of Aster tataricus
Satoru Sawai, H. Uchiyama, S. Mizuno, T. Aoki +3 more
2011FEBS Letters33 citations Open access
Semantic Scholar
New Scheme of the Biosynthesis of Formononetin Involving 2,7,4′-Trihydroxyisoflavanone but Not Daidzein as the Methyl Acceptor
T. Akashi, Y. Sawada, T. Aoki, S. Ayabe
2000Bioscience, biotechnology and biochemistry33 citations Open access
Semantic Scholar
A cDNA for polyketide reductase (accession No. D83718) that catalyzes the formation of 6'-deoxychalcone from cultured Glycyrrhiza echinata L. cells (PGR 96023).
T. Akashi
199629 citations
Semantic Scholar
Anthocyanin-producing dandelion callus as a chalcone synthase source in recombinant polyketide reductase assay.
T. Akashi, Norio Saito, H. Hirota, S. Ayabe
1997Phytochemistry26 citations
Semantic Scholar
Functional expression of cytochrome P450 in Escherichia coli: An approach to functional analysis of uncharacterized enzymes for flavonoid biosynthesis
Kai Uchida, T. Akashi, T. Aoki
201523 citations Open access
Semantic Scholar
Isoflavonoid production by adventitious-root cultures of Iris germanica (Iridaceae)
T. Akashi, Masayuki Ishizaki, T. Aoki, S. Ayabe
200523 citations Open access
Semantic Scholar
Cloning of cytochrome P450 cDNAs from cultured Glycyrrhiza echinata L. cells and their transcriptional activation by elicitor-treatment
T. Akashi, T. Aoki, Takeyoshi Takahashi, N. Kameya +2 more
199723 citations
Semantic Scholar
Functional characterization of CYP71D443, a cytochrome P450 catalyzing C-22 hydroxylation in the 20-hydroxyecdysone biosynthesis of Ajuga hairy roots.
Y. Tsukagoshi, K. Ohyama, H. Seki, T. Akashi +3 more
2016Phytochemistry22 citations Open access
Semantic Scholar
Phenolic Acids Induce Nod Factor Production in Lotus japonicus–Mesorhizobium Symbiosis
M. Shimamura, Takashi Kumaki, Shun Hashimoto, K. Saeki +5 more
2022Microbes and Environments18 citations Open access
Semantic Scholar
Genome-inspired search for new antibiotics. Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34
Shigehiro Tohyama, T. Eguchi, R. Dhakal, T. Akashi +2 more
200418 citations
Semantic Scholar
Molecular and Biochemical Characterization of 2-Hydroxyisoﬂavanone Dehydratase. Involvement of Carboxylesterase-Like Proteins in Leguminous Isoﬂavone Biosynthesis 1[w]
T. Akashi, T. Aoki, S. Ayabe
200517 citations
Semantic Scholar
Plant Phenolics: Phenylpropanoids
S. Ayabe, H. Uchiyama, T. Aoki, T. Akashi
201014 citations
Semantic Scholar
Catalytic specificity of pea O-methyltransferases suggests gene duplication for (+)-pisatin biosynthesis.
T. Akashi, H. Vanetten, Yuji Sawada, C. Wasmann +2 more
2006Phytochemistry14 citations
Semantic Scholar
Molecular Identification of UDP-Sugar-Dependent Glycosyltransferase and Acyltransferase Involved in the Phenylethanoid Glycoside Biosynthesis Induced by Methyl Jasmonate in Sesamum indicum L.
Yushiro Fuji, Kai Uchida, T. Akashi, T. Ohtsuki +2 more
2023Plant and Cell Physiology12 citations Open access
Semantic Scholar
Identification of flavonoid 8-hydroxylase with gossypetin synthase activity from flower specific EST data of Lotus Japonicus.
Yasuhide Hiraga, N. Shimada, Yoshiki Nagashima, Kunihiro Suda +12 more
2021Plant and Cell Physiology12 citations
Semantic Scholar
Cloning of cDNAs encoding P450s in flavonoid/isoflavonoid pathway from elicited leguminous cell cultures.
S. Ayabe, T. Akashi, T. Aoki
2002Methods in Enzymology11 citations
Semantic Scholar
Triterpenoid Constituents of Tissue Cultures and Regenerated Organs of Taraxacum officinale
T. Furuno, A. Kamiyama, T. Akashi, M. Usui +2 more
199311 citations Open access
Semantic Scholar
Identification and characterization of glycosyltransferases catalyzing direct xanthone 4‐C‐glycosylation in Hypericum perforatum
Kai Uchida, T. Akashi, M. Hirai
2021FEBS Letters10 citations Open access
Semantic Scholar
Molecular cloning and biochemical characterization of isoflav-3-ene synthase, a key enzyme of the biosyntheses of (+)-pisatin and coumestrol.
Kai Uchida, T. Aoki, Hideyuki Suzuki, T. Akashi
2020Plant Biotechnology9 citations Open access
Semantic Scholar
CYP71D8 and CYP82A2 catalyze the last committed step in biosynthesis of glyceollin isomers in soybean
T. Akashi, Kai Uchida, T. Aoki
2025Plant Biotechnology6 citations Open access
Semantic Scholar
Omics-based identification of the broader effects of 2-hydroxyisoflavanone synthase gene editing on a gene regulatory network beyond isoflavonoid loss in soybean hairy roots
Kai Uchida, Yushiro Fuji, Hiromitsu Tabeta, T. Akashi +1 more
2024Plant and Cell Physiology5 citations Open access
Semantic Scholar
Daidzein Hydroxylation by CYP81E63 is involved in the Biosynthesis of Miroestrol in Pueraria mirifica.
Nithiwat Suntichaikamolkul, T. Akashi, Panupong Mahalapbutr, Kamonpan Sanachai +7 more
2022Plant and Cell Physiology5 citations Open access
Semantic Scholar
Mutants of Lotus japonicus deficient in flavonoid biosynthesis
T. Aoki, M. Kawaguchi, H. Imaizumi-Anraku, S. Akao +2 more
2021Journal of plant research5 citations Open access
Semantic Scholar
Cloning and Functional Expression of a Cytochrome P 450 cDNA Encoding 2-Hydroxyisoflavanone Synthase Involved in Biosynthesis of the Isoflavonoid Skeleton in Licorice 1
T. Akashi, T. Aoki, S. Ayabe
19993 citations
Semantic Scholar
Molecular and Biochemical Characterization of 2-Hydroxyisoflavanone Dehydratase . Involvement of Carboxylesterase-Like Proteins in Leguminous Isoflavone Biosynthesis 1
T. Akashi, T. Aoki, S. Ayabe
20051 citations
Semantic Scholar
Applied fractal method to measurement of flocculation in wastewater treatment process
T. Akashi, Ei-Ichi Kojima, E. Ichikawa
1994Proceedings of IECON'94 - 20th Annual Conference of IEEE Industrial Electronics1 citations
Semantic Scholar

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T. Aoki — researcher profile on SciRah
S. Ayabe×33
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Kai Uchida×7
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Hideyuki Suzuki×5
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Hideyuki Suzuki — researcher profile on SciRah

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Satoru Sawai — researcher profile on SciRah

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T. Muranaka — researcher profile on SciRah

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Takeyoshi Takahashi — researcher profile on SciRah

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H. Seki — researcher profile on SciRah

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K. Ohyama — researcher profile on SciRah

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K. Saito — researcher profile on SciRah

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Yuji Sawada — researcher profile on SciRah