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N. Kairies · SciRah

Researcher profile · Semantic Scholar

N. Kairies

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N. Kairies — researcher profile on SciRah

h-index: 7
Works: 14
Citations: 1,022

Most-cited papers

Crystal Structure of Epoxomicin:20S Proteasome reveals a molecular basis for selectivity of alpha,beta-Epoxyketone Proteasome Inhibitors
M. Groll, K. B. Kim, N. Kairies, R. Huber +1 more
2000257 citations
Semantic Scholar
Structural basis for the activation of human procaspase-7
S. Riedl, P. Fuentes-Prior, M. Renatus, N. Kairies +4 more
2001Proceedings of the National Academy of Sciences of the United States of America230 citations Open access
Semantic Scholar
How an Inhibitor of the HIV-I Protease Modulates Proteasome Activity*
G. Schmidtke, H. Holzhütter, M. Bogyo, N. Kairies +4 more
1999Journal of Biological Chemistry174 citations Open access
Semantic Scholar
The 2.0-Å crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems
N. Kairies, H. Beisel, P. Fuentes-Prior, R. Tsuda +5 more
2001Proceedings of the National Academy of Sciences of the United States of America148 citations Open access
Semantic Scholar
Phthalazinone pyrazoles as potent, selective, and orally bioavailable inhibitors of Aurora-A kinase.
Michael E. Prime, S. M. Courtney, F. Brookfield, R. W. Marston +11 more
2011Journal of Medicinal Chemistry77 citations Open access
Semantic Scholar
Crystal structures of active SRC kinase domain complexes.
C. Breitenlechner, N. Kairies, K. Honold, Stefan Scheiblich +6 more
2005Journal of Molecular Biology74 citations
Semantic Scholar
Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8-ribityllumazine.
S. Gerhardt, A. Schott, N. Kairies, M. Cushman +6 more
2002Structure62 citations Open access
Semantic Scholar
Aurora kinase A complexed to pyrazole aminoquinoline I
T. Oliveira, N. Kairies, R. Engh
20140 citations
Semantic Scholar
Structure of Aurora kinase A complexed to benzoimidazole-indazole inhibitor XIII
T. Oliveira, N. Kairies, R. Engh
20140 citations
Semantic Scholar
Structure of Aurora kinase A complexed to pyrazole-aminoquinoline inhibitor III
T. Oliveira, N. Kairies, R. Engh
20140 citations
Semantic Scholar
Aurora A kinase domain with phthalazinone pyrazole inhibitor
N. Kairies, T. Oliveira, R. Engh
20110 citations
Semantic Scholar
Crystal structure of Src kinase domain
C. Breitenlechner, N. Kairies, K. Honold, Stefan Scheiblich +6 more
20060 citations
Semantic Scholar
Crystal structure of Src kinase domain in complex with CGP77675
C. Breitenlechner, N. Kairies, K. Honold, Stefan Scheiblich +6 more
20060 citations
Semantic Scholar
TACHYLECTIN 5A FROM TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB)
N. Kairies, H. Beisel, P. Fuentes-Prior, R. Tsuda +5 more
19990 citations
Semantic Scholar

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