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R. Castilho · SciRah

Researcher profile · Semantic Scholar

R. Castilho

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R. Castilho — researcher profile on SciRah

h-index: 34
Works: 118
Citations: 5,113

Most-cited papers

Dental implants‐associated release of titanium particles: A systematic review
Fernando Suárez-López del Amo, C. Garaicoa-Pazmiño, T. Fretwurst, R. Castilho +1 more
2018Clinical Oral Implants Research175 citations
Semantic Scholar
Epigenetic Modifications and Head and Neck Cancer: Implications for Tumor Progression and Resistance to Therapy
R. Castilho, C. Squarize, L. Almeida
2017International Journal of Molecular Sciences160 citations Open access
Semantic Scholar
TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer
R. Banerjee, Nickole Russo, Min Liu, V. Basrur +13 more
2014Nature Communications144 citations Open access
Semantic Scholar
Epigenetic Modifications of Histones in Periodontal Disease
M. Martins, Y. Jiao, Lena Larsson, L. Almeida +6 more
2016Journal of dentistry research118 citations
Semantic Scholar
Characterization of macrophage polarization in periodontal disease.
C. Garaicoa-Pazmiño, T. Fretwurst, C. Squarize, T. Berglundh +3 more
2019Journal of Clinical Periodontology117 citations Open access
Semantic Scholar
Epigenetics and its role in periodontal diseases: a state-of-the-art review.
L. Larsson, R. Castilho, W. Giannobile
2015The Journal of Periodontology115 citations Open access
Semantic Scholar
Characterization of macrophages infiltrating peri-implantitis lesions.
T. Fretwurst, C. Garaicoa-Pazmiño, K. Nelson, W. Giannobile +3 more
2019Clinical Oral Implants Research85 citations Open access
Semantic Scholar
Curcumin downregulates the PI3K–AKT–mTOR pathway and inhibits growth and progression in head and neck cancer cells
G. A. Borges, S. T. Elias, B. Amorim, Caroline L. Lima +4 more
2020Phytotherapy Research79 citations Open access
Semantic Scholar
New tendencies in non-surgical periodontal therapy.
A. Haas, F. Furlaneto, E. Gaio, S. Gomes +4 more
2021Brazilian Oral Research76 citations Open access
Semantic Scholar
ALDH/CD44 identifies uniquely tumorigenic cancer stem cells in salivary gland mucoepidermoid carcinomas
A. Adams, K. Warner, A. Pearson, Zhao-Cheng Zhang +8 more
2015OncoTarget76 citations Open access
Semantic Scholar
Titanium Activates the DNA Damage Response Pathway in Oral Epithelial Cells: A Pilot Study.
Fernando Suárez-López del Amo, I. Rudek, V. Wagner, M. Martins +5 more
2017The International Journal of Oral and Maxillofacial Implants70 citations Open access
Semantic Scholar
Immunotherapy improves efficacy and safety of patients with HPV positive and negative head and neck cancer: A systematic review and meta-analysis.
Marisol Miranda Galvis, G. A. Borges, T. B. de Oliveira, I. P. de Toledo +4 more
2020Critical reviews in oncology/hematology67 citations Open access
Semantic Scholar
Efficacy of laser phototherapy in comparison to topical clobetasol for the treatment of oral lichen planus: a randomized controlled trial
C. Dillenburg, M. A. T. Martins, M. C. Munerato, M. Marques +4 more
2014Journal of Biomedical Optics63 citations Open access
Semantic Scholar
Hypoacetylation of acetyl‐histone H3 (H3K9ac) as marker of poor prognosis in oral cancer
L. P. Webber, V. Wagner, M. Curra, P. Vargas +5 more
2017Histopathology62 citations
Semantic Scholar
Influence of epigenetics on periodontitis and peri-implantitis pathogenesis.
L. Larsson, Nolan M Kavanagh, T. Nguyen, R. Castilho +2 more
2022Periodontology 200061 citations Open access
Semantic Scholar
Laser phototherapy accelerates oral keratinocyte migration through the modulation of the mammalian target of rapamycin signaling pathway
A. C. A. Pellicioli, M. Martins, C. Dillenburg, M. Marques +2 more
2014Journal of Biomedical Optics60 citations Open access
Semantic Scholar
Cancer Stem Cells: Powerful Targets to Improve Current Anticancer Therapeutics
R. L. Bighetti-Trevisan, L. O. Sousa, R. Castilho, L. Almeida
2019Stem Cells International55 citations Open access
Semantic Scholar
Unlocking the chromatin of adenoid cystic carcinomas using HDAC inhibitors sensitize cancer stem cells to cisplatin and induces tumor senescence
L. Almeida, D. M. Guimarães, M. Martins, M. A. T. Martins +4 more
2017Stem Cell Research54 citations Open access
Semantic Scholar
PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells
Camila S. Matsumoto, L. Almeida, D. M. Guimarães, M. Martins +5 more
2016OncoTarget53 citations Open access
Semantic Scholar
Metformin-Loaded Nanospheres Laden Photocrosslinkable Gelatin Hydrogel for Bone Tissue Engineering
L. Qu, N. Dubey, J. Ribeiro, E. A. Bordini +4 more
2020Journal of The Mechanical Behavior of Biomedical Materials52 citations Open access
Semantic Scholar
The IL-6R and Bmi-1 axis controls self-renewal and chemoresistance of head and neck cancer stem cells
Alexandra E Herzog, K. Warner, Zhao-Cheng Zhang, E. Bellile +6 more
2021Cell Death and Disease40 citations Open access
Semantic Scholar
Evaluation of DNA methylation of inflammatory genes following treatment of chronic periodontitis: A pilot case–control study
F. Asa'ad, V. Bollati, G. Pagni, R. Castilho +6 more
2017Journal of Clinical Periodontology39 citations
Semantic Scholar
Sensitizing mucoepidermoid carcinomas to chemotherapy by targeted disruption of cancer stem cells
D. M. Guimarães, L. Almeida, M. Martins, K. Warner +6 more
2016OncoTarget34 citations Open access
Semantic Scholar
Adenoid Cystic Carcinoma from the salivary and lacrimal glands and the breast: different clinical outcomes to the same tumor.
C. Emerick, F. Mariano, P. Vargas, J. Nör +2 more
2022Critical reviews in oncology/hematology33 citations
Semantic Scholar
Immunohistological composition of peri-implantitis affected tissue around ceramic implants - A pilot study.
T. Fretwurst, J. Müller, L. Larsson, P. Bronsert +5 more
2020The Journal of Periodontology33 citations Open access
Semantic Scholar
UM-HACC-2A: MYB-NFIB fusion-positive human adenoid cystic carcinoma cell line
K. Warner, A. E. Oklejas, A. Pearson, Zhao-Cheng Zhang +6 more
2018Oral Oncology33 citations Open access
Semantic Scholar
PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells
Chiara Zagni, L. Almeida, T. Balan, Marco Antônio Trevizani Martins +4 more
2017Stem Cell Reports30 citations Open access
Semantic Scholar
Profiling the Behavior of Distinct Populations of Head and Neck Cancer Stem Cells
L. Almeida, D. M. Guimarães, C. Squarize, R. Castilho
2016Cancers30 citations Open access
Semantic Scholar
BMAL1 Modulates Epidermal Healing in a Process Involving the Antioxidative Defense Mechanism
É. J. Silveira, C. H. V. Nascimento, V. Yujra, L. P. Webber +2 more
2020International Journal of Molecular Sciences29 citations Open access
Semantic Scholar
When epigenetics meets bioengineering—A material characteristics and surface topography perspective
L. Larsson, Sophia P Pilipchuk, W. Giannobile, R. Castilho
2017Journal of Biomedical Materials Research. Part B - Applied biomaterials29 citations Open access
Semantic Scholar
mTOR pathway protein immunoexpression as a prognostic factor for survival in head and neck cancer patients: a systematic review and meta-analysis.
A. E. M. Marques, S. T. Elias, A. Porporatti, R. Castilho +3 more
2016Journal of Oral Pathology & Medicine28 citations
Semantic Scholar
Comparative analysis between extra-short implants (≤ 6mm) and 6mm-longer implants: A Meta-Analysis of Randomized Controlled Trial.
G. V. de Oliveira Fernandes, Bruno Costa, Hiram Fisher Trindade, R. Castilho +1 more
2022Australian dental journal27 citations Open access
Semantic Scholar
Corrigendum: TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer
R. Banerjee, Nickole Russo, Min Liu, V. Basrur +13 more
2016Nature Communications27 citations Open access
Semantic Scholar
Skin wound healing triggers epigenetic modifications of histone H4
C. H. V. Nascimento-Filho, É. J. Silveira, E. Goloni-Bertollo, L. D. de Souza +2 more
2020Journal of Translational Medicine26 citations Open access
Semantic Scholar
Entinostat is a Novel Therapeutic Agent to Treat Oral Squamous Cell Carcinoma.
A. E. M. Marques, C. H. V. Nascimento, Thamara M. Marinho Bezerra, E. Guerra +2 more
2020Journal of Oral Pathology & Medicine26 citations Open access
Semantic Scholar
Epigenetic Modifications and Accumulation of DNA Double-Strand Breaks in Oral Lichen Planus Lesions Presenting Poor Response to Therapy
C. Dillenburg, M. A. T. Martins, L. Almeida, L. Meurer +3 more
2015Medicine26 citations Open access
Semantic Scholar
Targeting histone deacetylase and NFκB signaling as a novel therapy for Mucoepidermoid Carcinomas
V. Wagner, M. Martins, M. A. T. Martins, L. Almeida +4 more
2018Scientific Reports25 citations Open access
Semantic Scholar
Cephaeline is an inductor of histone H3 acetylation and inhibitor of mucoepidermoid carcinoma cancer stem cells
Luan César da Silva, G. Borgato, V. Wagner, M. Martins +9 more
2021Journal of Oral Pathology & Medicine23 citations Open access
Semantic Scholar
Understanding the role of endotoxin tolerance in chronic inflammatory conditions and periodontal disease.
L. Larsson, C. Garaicoa-Pazmino, F. Asa'ad, R. Castilho
2021Journal of Clinical Periodontology22 citations Open access
Semantic Scholar
Worldwide Prevalence of PI3K-AKT-mTOR Pathway Mutations in Head and Neck Cancer: A Systematic Review and Meta-Analysis.
Adriana Castelo Caracas de Moura, D. Assad, Juliana Amorim dos Santos, I. P. de Toledo +4 more
2021Critical reviews in oncology/hematology22 citations
Semantic Scholar
DNA intercalators based on (1,10-phenanthrolin-2-yl)isoxazolidin-5-yl core with better growth inhibition and selectivity than cisplatin upon head and neck squamous cells carcinoma.
M. G. Varrica, Chiara Zagni, P. Mineo, G. Floresta +7 more
2018European journal of medicinal chemistry22 citations
Semantic Scholar
Overexpression of MutSα Complex Proteins Predicts Poor Prognosis in Oral Squamous Cell Carcinoma
V. Wagner, L. P. Webber, G. Salvadori, L. Meurer +5 more
2016Medicine22 citations Open access
Semantic Scholar
Synergistic Efficacy of Combined EGFR and HDAC Inhibitors Overcomes Tolerance to EGFR Monotherapy in Salivary Mucoepidermoid Carcinoma
Kshitij Parag-Sharma, J. Tasoulas, Adele M. Musicant, Carlos H. Viesi Do Nascimento-Filho +5 more
2021Oral Oncology21 citations Open access
Semantic Scholar
Photobiomodulation therapy drives massive epigenetic histone modifications, stem cells mobilization and accelerated epithelial healing
M. Martins, F. Silveira, M. A. Martins, L. Almeida +3 more
2020Journal of Biophotonics21 citations Open access
Semantic Scholar
Pharmacological PTEN inhibition: potential clinical applications and effects in tissue regeneration.
G. A. Borges, L. P. Webber, A. E. M. Marques, E. N. Guerra +2 more
2020Regenerative medicine21 citations Open access
Semantic Scholar
Hypoxic niches are endowed with a protumorigenic mechanism that supersedes the protective function of PTEN
Carlos H. V. Nascimento-Filho, L. P. Webber, Gabriell B. Borgato, E. Goloni-Bertollo +2 more
2019The FASEB Journal21 citations Open access
Semantic Scholar
Interference with the Bromodomain Epigenome Readers Drives p21 Expression and Tumor Senescence
L. P. Webber, V. Yujra, P. Vargas, M. Martins +2 more
2019Cancer Letters20 citations Open access
Semantic Scholar
Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKK-β/IκBα/NFκB axis
V. Wagner, M. A. Martins, M. Martins, K. Warner +4 more
2016OncoTarget20 citations Open access
Semantic Scholar
Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma
K. Warner, Felipe Nör, Gerson A Acasigua, M. Martins +11 more
2016Clinical Cancer Research20 citations Open access
Semantic Scholar
miR-22 and miR-205 Drive Tumor Aggressiveness of Mucoepidermoid Carcinomas of Salivary Glands
Erika Naakka, M. Barros-Filho, S. Adnan-Awad, A. Al-Samadi +15 more
2022Frontiers in Oncology19 citations Open access
Semantic Scholar

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