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Tiffany J Mellott · SciRah

Researcher profile · Semantic Scholar

Tiffany J Mellott

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Tiffany J Mellott — researcher profile on SciRah

h-index: 21
Works: 35
Citations: 1,773

Most-cited papers

Neuroprotective Actions of Dietary Choline
J. Blusztajn, B. Slack, Tiffany J Mellott
2017Nutrients244 citations Open access
Semantic Scholar
Gestational Choline Deficiency Causes Global and Igf2 Gene DNA Hypermethylation by Up-regulation of Dnmt1 Expression*
V. Kovacheva, Tiffany J Mellott, J. M. Davison, Nicholas Wagner +3 more
2007Journal of Biological Chemistry232 citations Open access
Semantic Scholar
Gestational Choline Supply Regulates Methylation of Histone H3, Expression of Histone Methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA Methylation of Their Genes in Rat Fetal Liver and Brain*
J. M. Davison, Tiffany J Mellott, V. Kovacheva, J. Blusztajn
2009Journal of Biological Chemistry159 citations Open access
Semantic Scholar
Choline nutrition programs brain development via DNA and histone methylation
J. Blusztajn, Tiffany J Mellott
2012Central Nervous System Agents in Medicinal Chemistry104 citations Open access
Semantic Scholar
IGF2 Ameliorates Amyloidosis, Increases Cholinergic Marker Expression and Raises BMP9 and Neurotrophin Levels in the Hippocampus of the APPswePS1dE9 Alzheimer’s Disease Model Mice
Tiffany J Mellott, S. Pender, R. Burke, Erika A. Langley +1 more
2014PLoS ONE93 citations Open access
Semantic Scholar
Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats
Melissa J. Glenn, E. D. Kirby, Erin M. Gibson, Sarah J. E. Wong-Goodrich +3 more
2008Brain Research90 citations Open access
Semantic Scholar
Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero
Sarah J. E. Wong-Goodrich, Melissa J. Glenn, Tiffany J Mellott, J. Blusztajn +2 more
2008Brain Research76 citations Open access
Semantic Scholar
Effects of postnatal dietary choline supplementation on motor regional brain volume and growth factor expression in a mouse model of Rett syndrome.
N. Nag, Tiffany J Mellott, J. Berger-Sweeney
2008Brain Research69 citations
Semantic Scholar
Prenatal choline supplementation in rats increases the expression of IGF2 and its receptor IGF2R and enhances IGF2-induced acetylcholine release in hippocampus and frontal cortex.
Isabella Nápoli, J. Blusztajn, Tiffany J Mellott
2008Brain Research68 citations
Semantic Scholar
Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus.
Sarah J. E. Wong-Goodrich, Tiffany J Mellott, Melissa J. Glenn, J. Blusztajn +1 more
2008Neurobiology of Disease68 citations Open access
Semantic Scholar
High Maternal Choline Consumption During Pregnancy and Nursing Alleviates Deficits in Social Interaction and Improves Anxiety‐like Behaviors in the BTBR T+Itpr3tf /J Mouse Model of Autism
Erika A. Langley, Marina Krykbaeva, J. Blusztajn, Tiffany J Mellott
2015Behavioural Brain Research66 citations
Semantic Scholar
Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons.
I. López-Coviella, M. Follettie, Tiffany J Mellott, V. Kovacheva +5 more
2005Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer’s disease
R. Burke, Timothy A. Norman, T. Haydar, B. Slack +3 more
2013Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice
Tiffany J Mellott, Olivia M. Huleatt, Bethany N. Shade, S. Pender +3 more
2017PLoS ONE49 citations Open access
Semantic Scholar
Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood
Sarah J. E. Wong-Goodrich, Melissa J. Glenn, Tiffany J Mellott, Yi B. Liu +2 more
2010Hippocampus44 citations Open access
Semantic Scholar
Neuroprotective actions of perinatal choline nutrition
J. Blusztajn, Tiffany J Mellott
2013Clinical Chemistry and Laboratory Medicine40 citations Open access
Semantic Scholar
BMP9 induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons
A. Schnitzler, Tiffany J Mellott, I. López-Coviella, Yvonne N. Tallini +3 more
2010Journal of Neuroscience40 citations Open access
Semantic Scholar
Prenatal choline deficiency increases choline transporter expression in the septum and hippocampus during postnatal development and in adulthood in rats.
Tiffany J Mellott, N. Kowall, I. López-Coviella, J. Blusztajn
2007Brain Research39 citations Open access
Semantic Scholar
Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War Illness in a mouse model of the disease
I. Carreras, Nurgul Aytan, Tiffany J Mellott, Ji-Kyung Choi +6 more
2017Brain Research30 citations Open access
Semantic Scholar
BMP9 Protects Septal Neurons from Axotomy-Evoked Loss of Cholinergic Phenotype
I. López-Coviella, Tiffany J Mellott, A. Schnitzler, J. Blusztajn
2011PLoS ONE24 citations Open access
Semantic Scholar
Perinatal choline deficiency produces abnormal sensory inhibition in Sprague-Dawley rats
K. Stevens, C. Adams, Tiffany J Mellott, Emily Robbins +1 more
2008Brain Research22 citations Open access
Semantic Scholar
A Narrative Review on Maternal Choline Intake and Liver Function of the Fetus and the Infant; Implications for Research, Policy, and Practice
R. Obeid, C. Schön, E. Derbyshire, Xin-Yin Jiang +3 more
2024Nutrients17 citations Open access
Semantic Scholar
Perinatal choline supplementation prevents learning and memory deficits and reduces brain amyloid Aβ42 deposition in AppNL-G-F Alzheimer’s disease model mice
Thomas A Bellio, Jessenia Y Laguna-Torres, Mary S Campion, Jay Chou +3 more
2024PLoS ONE14 citations Open access
Semantic Scholar
Defective Immune Function of Primary Effusion Lymphoma Cells is Associated with Distinct KSHV Gene Expression Profiles
T. Suscovich, Mini Paulose-Murphy, Jason D. Harlow, Yidong Chen +6 more
2004Leukemia and Lymphoma13 citations
Semantic Scholar
Mitogen-activated protein kinase kinase negatively modulates ciliary neurotrophic factor-activated choline acetyltransferase gene expression.
Tiffany J Mellott, I. López-Coviella, J. Blusztajn, B. Berse
2002European Journal of Biochemistry11 citations
Semantic Scholar
Cerebral gray- and white matter monogalactosyl diglyceride levels rise with the progression of Alzheimer’s disease
J. K. Blusztajn, Nurgul Aytan, Thekkelnaycke M. Rajendiran, Tiffany J Mellott +6 more
2023Journal of Alzheimer's Disease9 citations Open access
Semantic Scholar
Correction: Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice
Tiffany J Mellott, Olivia M. Huleatt, Bethany N. Shade, S. Pender +3 more
2017PLoS ONE9 citations Open access
Semantic Scholar
Immunohistochemical Analysis of Activin Receptor-Like Kinase 1 (ACVRL1/ALK1) Expression in the Rat and Human Hippocampus: Decline in CA3 During Progression of Alzheimer’s Disease
Stephanie L. Adams, L. Benayoun, Kathy Tilton, Tiffany J Mellott +3 more
2018Journal of Alzheimer's Disease7 citations Open access
Semantic Scholar
Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood
Sarah J. E. Wong-Goodrich, Christina M. Tognoni, Tiffany J Mellott, Melissa J. Glenn +2 more
2011Brain Research7 citations Open access
Semantic Scholar
Brain DNA Methylation Atlas of AppNL‐G‐F Alzheimer's Disease Model Mice Across Age and Region Reveals Choline‐Induced Resilience
Andre Krunic, Thomas A Bellio, Benjamin Z Cohen, A. Labadorf +4 more
2025Aging Cell4 citations Open access
Semantic Scholar
Perinatal Choline Supplementation Promotes Resilience Against Progression of Alzheimer's Disease‐Like Brain Transcriptomic Signatures in App NL‐G‐F Mice
Thomas A Bellio, Andre Krunic, Mary S Campion, Rohan Dupaguntla +5 more
2025Aging Cell2 citations Open access
Semantic Scholar
Corrigendum to "Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease" [Brain Res. 1681 (2018) 34-43].
I. Carreras, Nurgul Aytan, Tiffany J Mellott, Ji-Kyung Choi +6 more
2018Brain Research1 citations
Semantic Scholar
Perinatal Choline Supplementation Reduces Amyloidosis and Increases Cholinergic Marker Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice
Tiffany J Mellott, Olivia M. Huleatt, Bethany N. Shade, S. Pender +2 more
20151 citations
Semantic Scholar
MicroRNA-223 Enhances Microglia-Dependent Clearance of Amyloid Beta Plaques and Ameliorates Behavioral Deficits in a Mouse Model of Alzheimer’s Disease
Andre Krunic, Nikkitha Umesh Ganesh, Ugur Coskun, William Brennan +16 more
2026bioRxiv0 citations Open access
Semantic Scholar
Subtype-Specific Inhibition of Nicotinic Acetylcholine Receptors by Choline: A Regulatory
D. Turner, C. Williams, W. Meck, Tiffany J Mellott +5 more
20080 citations
Semantic Scholar

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