Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

C. Norez · SciRah

Researcher profile · Semantic Scholar

C. Norez

Share profile

C. Norez — researcher profile on SciRah

h-index: 30
Works: 94
Citations: 2,404

Most-cited papers

Rescue of functional delF508‐CFTR channels in cystic fibrosis epithelial cells by the α‐glucosidase inhibitor miglustat
C. Norez, S. Noel, M. Wilke, M. Bijvelds +4 more
2006FEBS Letters146 citations
Semantic Scholar
Missense mutations in SLC26A8, encoding a sperm-specific activator of CFTR, are associated with human asthenozoospermia.
Thassadite Dirami, B. Rode, Mathilde Jollivet, Nathalie Da Silva +11 more
2013American Journal of Human Genetics110 citations Open access
Semantic Scholar
Sildenafil (Viagra) corrects ΔF508-CFTR location in nasal epithelial cells from patients with cystic fibrosis
R. Dormer, C. M. Harris, Zoe Elizabeth Clark, M. Pereira +4 more
2004Thorax100 citations Open access
Semantic Scholar
Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain
Norbert Odolczyk, J. Fritsch, C. Norez, N. Servel +19 more
2013EMBO Molecular Medicine86 citations Open access
Semantic Scholar
The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation.
B. Rode, Thassadite Dirami, N. Bakouh, M. Rizk-Rabin +12 more
2012Human Molecular Genetics86 citations
Semantic Scholar
Maintaining Low Ca2+ Level in the Endoplasmic Reticulum Restores Abnormal Endogenous F508del‐CFTR Trafficking in Airway Epithelial Cells
C. Norez, F. Antigny, F. Becq, C. Vandebrouck
2006Traffic : the International Journal of Intracellular Transport83 citations
Semantic Scholar
Disruption of CFTR chloride channel alters mechanical properties and cAMP‐dependent Cl− transport of mouse aortic smooth muscle cells
R. Robert, C. Norez, F. Becq
2005Journal of Physiology83 citations Open access
Semantic Scholar
Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR.
F. Antigny, C. Norez, F. Becq, C. Vandebrouck
2008Cell Calcium77 citations
Semantic Scholar
Evidence that CFTR is expressed in rat tracheal smooth muscle cells and contributes to bronchodilation
C. Vandebrouck, Patricia Melin, C. Norez, R. Robert +3 more
2006Respiratory Research73 citations Open access
Semantic Scholar
Rescue of ΔF508-CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) by Curcumin: Involvement of the Keratin 18 Network
J. Lipecka, C. Norez, N. Bensalem, M. Baudouin-legros +4 more
2006Journal of Pharmacology and Experimental Therapeutics72 citations
Semantic Scholar
A cystic fibrosis respiratory epithelial cell chronically treated by miglustat acquires a non-cystic fibrosis-like phenotype.
C. Norez, F. Antigny, S. Noel, C. Vandebrouck +1 more
2009American Journal of Respiratory Cell and Molecular Biology66 citations Open access
Semantic Scholar
Syntaxin 8 impairs trafficking of cystic fibrosis transmembrane conductance regulator (CFTR) and inhibits its channel activity
F. Bilan, V. Thoreau, Magali Nacfer, R. Dérand +5 more
2004Journal of Cell Science65 citations Open access
Semantic Scholar
Transient receptor potential canonical channel 6 links Ca2+ mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis.
F. Antigny, C. Norez, L. Dannhoffer, J. Bertrand +5 more
2011American Journal of Respiratory Cell and Molecular Biology60 citations
Semantic Scholar
Synthesis, SAR, crystal structure, and biological evaluation of benzoquinoliziniums as activators of wild-type and mutant cystic fibrosis transmembrane conductance regulator channels.
Cécile Marivingt-Mounir, C. Norez, R. Dérand, L. Bulteau-Pignoux +6 more
2004Journal of Medicinal Chemistry59 citations Open access
Semantic Scholar
Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Channel by β-Adrenergic Agonists and Vasoactive Intestinal Peptide in Rat Smooth Muscle Cells and Its Role in Vasorelaxation*
R. Robert, V. Thoreau, C. Norez, A. Cantereau +4 more
2004Journal of Biological Chemistry59 citations Open access
Semantic Scholar
CFTR and Ca2+ Signaling in Cystic Fibrosis
F. Antigny, C. Norez, F. Becq, C. Vandebrouck
2011Frontiers in Pharmacology58 citations Open access
Semantic Scholar
Anti-inflammatory effect of miglustat in bronchial epithelial cells.
M. Dechecchi, E. Nicolis, C. Norez, V. Bezzerri +7 more
2008Journal of Cystic Fibrosis57 citations Open access
Semantic Scholar
Determination of CFTR chloride channel activity and pharmacology using radiotracer flux methods.
C. Norez, G. D. Heda, T. Jensen, Ilana Kogan +11 more
2004Journal of Cystic Fibrosis51 citations Open access
Semantic Scholar
Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.
N. Ardès-Guisot, D. Alonzi, Gabriele Reinkensmeier, T. Butters +8 more
2011Organic and biomolecular chemistry46 citations
Semantic Scholar
C-branched iminosugars: α-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP compared to miglitol and miglustat.
S. F. Jenkinson, D. Best, A. W. Saville, J. Mui +12 more
2013Journal of Organic Chemistry45 citations
Semantic Scholar
Cystic fibrosis and diabetes: isoLAB and isoDAB, enantiomeric carbon-branched pyrrolidine iminosugars
D. Best, S. F. Jenkinson, A. W. Saville, D. Alonzi +8 more
201045 citations
Semantic Scholar
Modulating innate and adaptative immunity by (R)-roscovitine: potential therapeutic opportunity in cystic fibrosis
L. Meijer, D. Nelson, V. Riazanski, A. Gabdoulkhakova +19 more
2016Journal of Innate Immunity44 citations Open access
Semantic Scholar
Abnormal spatial diffusion of Ca2+ in F508del-CFTR airway epithelial cells
F. Antigny, C. Norez, A. Cantereau, F. Becq +1 more
2008Respiratory Research42 citations Open access
Semantic Scholar
Expression and function of cystic fibrosis transmembrane conductance regulator in rat intrapulmonary arteries
R. Robert, J. Savineau, C. Norez, F. Becq +1 more
2007European Respiratory Journal42 citations
Semantic Scholar
The cystic fibrosis mutation G1349D within the signature motif LSHGH of NBD2 abolishes the activation of CFTR chloride channels by genistein.
Patricia Melin, V. Thoreau, C. Norez, F. Bilan +2 more
2004Biochemical Pharmacology42 citations
Semantic Scholar
Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation.
R. Dérand, L. Bulteau-Pignoux, Y. Mettey, O. Zegarra-Moran +9 more
2001American Journal of Physiology - Cell Physiology42 citations
Semantic Scholar
Discovery of Pyrrolo[2,3-b]pyrazines Derivatives as Submicromolar Affinity Activators of Wild Type, G551D, and F508del Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels
S. Noel, Christelle Faveau, C. Norez, C. Rogier +2 more
2006Journal of Pharmacology and Experimental Therapeutics41 citations
Semantic Scholar
Rescue of Functional CFTR Channels in Cystic Fibrosis: A Dramatic Multivalent Effect Using Iminosugar Cluster‐Based Correctors
Philippe Compain, Camille Decroocq, A. Joosten, J. D. de Sousa +7 more
2013ChemBioChem39 citations
Semantic Scholar
4-C-Me-DAB and 4-C-Me-LAB – enantiomeric alkyl-branched pyrrolidine iminosugars – are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group
Filipa P. da Cruz, S. Newberry, S. F. Jenkinson, M. Wormald +8 more
2011Tetrahedron Letters33 citations Open access
Semantic Scholar
Endosomal SNARE proteins regulate CFTR activity and trafficking in epithelial cells.
F. Bilan, Magali Nacfer, F. Fresquet, C. Norez +6 more
2008Experimental Cell Research30 citations
Semantic Scholar
Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del‐CFTR by a CDK‐independent mechanism
C. Norez, C. Vandebrouck, J. Bertrand, Sabrina Noël +8 more
2014British Journal of Pharmacology29 citations Open access
Semantic Scholar
CFTR mutation combinations producing frequent complex alleles with different clinical and functional outcomes
A. El-Seedy, E. Girodon, C. Norez, J. Pajaud +12 more
2012Human Mutation28 citations Open access
Semantic Scholar
Proteasome-Dependent Pharmacological Rescue of Cystic Fibrosis Transmembrane Conductance Regulator Revealed by Mutation of Glycine 622
C. Norez, F. Bilan, A. Kitzis, Y. Mettey +1 more
2008Journal of Pharmacology and Experimental Therapeutics28 citations
Semantic Scholar
SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells.
R. Philippe, F. Antigny, P. Buscaglia, C. Norez +3 more
2015Biochimica et Biophysica Acta27 citations Open access
Semantic Scholar
Adenovirus 5–Fiber 35 Chimeric Vector Mediates Efficient Apical Correction of the Cystic Fibrosis Transmembrane Conductance Regulator Defect in Cystic Fibrosis Primary Airway Epithelia
O. Granio, K. J. Ashbourne Excoffon, P. Henning, Patricia Melin +10 more
2010Human Gene Therapy26 citations
Semantic Scholar
ANO1 contributes to angiotensin-II-activated Ca2+-dependent Cl- current in human atrial fibroblasts.
A. El Chemaly, C. Norez, C. Magaud, J. Bescond +7 more
2014Journal of Molecular and Cellular Cardiology25 citations
Semantic Scholar
Transient receptor potential vanilloid 1 (TRPV1) channels in cultured rat Sertoli cells regulate an acid sensing chloride channel.
C. Auzanneau, C. Norez, F. Antigny, V. Thoreau +4 more
2008Biochemical Pharmacology25 citations Open access
Semantic Scholar
Cellular localization and activity of Ad-delivered GFP-CFTR in airway epithelial and tracheal cells.
O. Granio, C. Norez, K. J. Ashbourne Excoffon, Philip H. Karp +5 more
2007American Journal of Respiratory Cell and Molecular Biology25 citations
Semantic Scholar
Discovery of α-Aminoazaheterocycle-Methylglyoxal Adducts as a New Class of High-Affinity Inhibitors of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels
C. Routaboul, C. Norez, Patricia Melin, Marie-Carmen Molina +7 more
2007Journal of Pharmacology and Experimental Therapeutics23 citations
Semantic Scholar
Calumenin contributes to ER-Ca2+ homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention.
R. Philippe, F. Antigny, P. Buscaglia, C. Norez +7 more
2017Cell Calcium21 citations
Semantic Scholar
The low PLC-δ1 expression in cystic fibrosis bronchial epithelial cells induces upregulation of TRPV6 channel activity.
Laura Vachel, C. Norez, C. Jayle, F. Becq +1 more
2015Cell Calcium21 citations
Semantic Scholar
N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors.
J. Désiré, M. Mondon, N. Fontelle, S. Nakagawa +14 more
2014Organic and biomolecular chemistry21 citations
Semantic Scholar
Synthetic deoxynojirimycin derivatives bearing a thiolated, fluorinated or unsaturated N-alkyl chain: identification of potent α-glucosidase and trehalase inhibitors as well as F508del-CFTR correctors.
V. Cendret, Thibaut Legigan, Agnès Mingot, S. Thibaudeau +9 more
2015Organic and biomolecular chemistry20 citations Open access
Semantic Scholar
Rescue of Functional F508del Cystic Fibrosis Transmembrane Conductance Regulator by Vasoactive Intestinal Peptide in the Human Nasal Epithelial Cell Line JME/CF15
Sara A. Rafferty, Nicole Alcolado, C. Norez, Frédéric G. Chappe +3 more
2009Journal of Pharmacology and Experimental Therapeutics20 citations
Semantic Scholar
Bronchorelaxation of the human bronchi by CFTR activators.
C. Norez, C. Jayle, F. Becq, C. Vandebrouck
2014Pulmonary Pharmacology & Therapeutics19 citations
Semantic Scholar
Effect of VX-770 (ivacaftor) and OAG on Ca2+ influx and CFTR activity in G551D and F508del-CFTR expressing cells.
Laura Vachel, C. Norez, F. Becq, C. Vandebrouck
2013Journal of Cystic Fibrosis16 citations Open access
Semantic Scholar
Guanabenz, an alpha2-selective adrenergic agonist, activates Ca2+-dependent chloride currents in cystic fibrosis human airway epithelial cells.
C. Norez, C. Vandebrouck, F. Antigny, L. Dannhoffer +2 more
2008European Journal of Pharmacology16 citations Open access
Semantic Scholar
Pharmacological profile of inhibition of the chloride channels activated by extracellular acid in cultured rat Sertoli cells.
C. Auzanneau, C. Norez, Sabrina Noël, C. Jougla +2 more
2006Reproduction, nutrition, development14 citations Open access
Semantic Scholar
General anesthetic octanol and related compounds activate wild‐type and delF508 cystic fibrosis chloride channels
Brice Marcet, F. Becq, C. Norez, P. Delmas +1 more
2004British Journal of Pharmacology14 citations Open access
Semantic Scholar
The Glycine Residues G551 and G1349 within the ATP-Binding Cassette Signature Motifs Play Critical Roles in the Activation and Inhibition of Cystic Fibrosis Transmembrane Conductance Regulator Channels by Phloxine B
Patricia Melin, C. Norez, I. Callebaut, F. Becq
2006Journal of Membrane Biology13 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

F. Becq×50
Invite
F. Becq — researcher profile on SciRah
C. Vandebrouck×14
Invite
C. Vandebrouck — researcher profile on SciRah
F. Antigny×10
Invite
F. Antigny — researcher profile on SciRah
Patricia Melin×8
Invite
Patricia Melin — researcher profile on SciRah

×6

Invite

Y. Mettey — researcher profile on SciRah

Invite

A. Kitzis — researcher profile on SciRah

Invite

T. Butters — researcher profile on SciRah

Invite

R. Robert — researcher profile on SciRah

Invite

V. Thoreau — researcher profile on SciRah

Invite

D. Alonzi — researcher profile on SciRah

Invite

A. Kato — researcher profile on SciRah

Invite

Y. Blériot — researcher profile on SciRah