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B. Eckes · SciRah

Researcher profile · Semantic Scholar

B. Eckes

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B. Eckes — researcher profile on SciRah

h-index: 55
Works: 177
Citations: 9,053

Most-cited papers

Cell-matrix interactions in dermal repair and scarring
B. Eckes, R. Nischt, T. Krieg
2010Fibrogenesis & Tissue Repair200 citations Open access
Semantic Scholar
Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice.
C. Deppermann, Deya Cherpokova, P. Nurden, Jan-Niklas Schulz +12 more
2013Journal of Clinical Investigation190 citations Open access
Semantic Scholar
Expression of integrin β1 by fibroblasts is required for tissue repair in vivo
Shang-Xin Liu, Shi-Jie Xu, K. Blumbach, M. Eastwood +5 more
2010Journal of Cell Science177 citations Open access
Semantic Scholar
Collagen XII and XIV, New Partners of Cartilage Oligomeric Matrix Protein in the Skin Extracellular Matrix Suprastructure*
Pallavi Agarwal, Daniela Zwolanek, D. Keene, Jan-Niklas Schulz +7 more
2012Journal of Biological Chemistry131 citations Open access
Semantic Scholar
TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators
Julian Nüchel, S. Ghatak, Alexandra V. Zuk, A. Illerhaus +8 more
2018Autophagy116 citations Open access
Semantic Scholar
The Fibroblast Integrin α11β1 Is Induced in a Mechanosensitive Manner Involving Activin A and Regulates Myofibroblast Differentiation*
Sergio Carracedo, Ning Lu, S. Popova, R. Jonsson +2 more
2010Journal of Biological Chemistry116 citations Open access
Semantic Scholar
Integrin α2β1 Is the Required Receptor for Endorepellin Angiostatic Activity*
Benjamin P. Woodall, A. Nyström, Rex A. Iozzo, J. Eble +5 more
2008Journal of Biological Chemistry103 citations Open access
Semantic Scholar
Deep Proteome Profiling Reveals Common Prevalence of MZB1‐Positive Plasma B Cells in Human Lung and Skin Fibrosis
H. Schiller, C. Mayr, G. Leuschner, M. Strunz +10 more
2017American Journal of Respiratory and Critical Care Medicine100 citations Open access
Semantic Scholar
TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy
A. Zehender, Yi-Nan Li, N. Lin, A. Stefanica +16 more
2018Nature Communications96 citations Open access
Semantic Scholar
Fibroblast-Derived MMP-14 Regulates Collagen Homeostasis in Adult Skin
P. Zigrino, J. Brinckmann, A. Niehoff, Yin-Hui Lu +4 more
2016Journal of Investigative Dermatology88 citations Open access
Semantic Scholar
COMP-assisted collagen secretion – a novel intracellular function required for fibrosis
Jan-Niklas Schulz, Julian Nüchel, A. Niehoff, W. Bloch +9 more
2016Journal of Cell Science84 citations Open access
Semantic Scholar
alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma?
Agatha Kokot, A. Sindrilaru, M. Schiller, C. Sunderkötter +5 more
2009Arthritis & Rheumatism82 citations
Semantic Scholar
New developments on skin fibrosis - Essential signals emanating from the extracellular matrix for the control of myofibroblasts.
Jan-Niklas Schulz, M. Plomann, G. Sengle, D. Gullberg +2 more
2018Matrix Biology81 citations
Semantic Scholar
Reduced Granulation Tissue and Wound Strength in the Absence of α11β1 Integrin
Jan-Niklas Schulz, C. Zeltz, Ida W. Sørensen, M. Barczyk +5 more
2015Journal of Investigative Dermatology79 citations Open access
Semantic Scholar
An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
Julian Nüchel, Marina Tauber, J. Nolte, M. Mörgelin +4 more
2021Molecules and Cells74 citations Open access
Semantic Scholar
Genetic ablation of mast cells redefines the role of mast cells in skin wound healing and bleomycin-induced fibrosis.
S. Willenborg, B. Eckes, J. Brinckmann, T. Krieg +4 more
2014Journal of Investigative Dermatology73 citations Open access
Semantic Scholar
Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice.
D. Rubel, Jenny Frese, M. Martín, Alexander Leibnitz +5 more
2014Matrix Biology71 citations
Semantic Scholar
Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity.
A. Nyström, Zabeena P. Shaik, D. Gullberg, T. Krieg +4 more
2009Blood70 citations Open access
Semantic Scholar
The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing
R. Rashmi, B. Eckes, G. Glöckner, Marco Groth +8 more
2012The Nucleus65 citations Open access
Semantic Scholar
Stabilization of integrin‐linked kinase by the Hsp90‐CHIP axis impacts cellular force generation, migration and the fibrotic response
Korana Radovanac, Jessica Morgner, Jan-Niklas Schulz, K. Blumbach +7 more
2013EMBO Journal63 citations Open access
Semantic Scholar
Enhanced deposition of cartilage oligomeric matrix protein is a common feature in fibrotic skin pathologies.
Pallavi Agarwal, Jan-Niklas Schulz, K. Blumbach, K. Andréasson +6 more
2013Matrix Biology62 citations
Semantic Scholar
The loss of α2β1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis.
M. Peters, D. Wendholt, S. Strietholt, S. Frank +7 more
2012Arthritis & Rheumatism60 citations
Semantic Scholar
Inhibition of integrin α2β1 ameliorates glomerular injury.
C. Borza, Yan Su, Xiwu Chen, Ling Yu +11 more
2012Journal of the American Society of Nephrology59 citations Open access
Semantic Scholar
Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts – role of TGFβ1 levels and RhoA activity
K. Blumbach, M. Zweers, G. Brunner, A. Peters +8 more
2010Journal of Cell Science59 citations Open access
Semantic Scholar
Role of collagen XII in skin homeostasis and repair.
K. Schönborn, S. Willenborg, Jan-Niklas Schulz, T. Imhof +8 more
2020Matrix Biology57 citations
Semantic Scholar
Integrin α2-deficient mice provide insights into specific functions of collagen receptors in the kidney
R. Girgert, M. Martín, J. Kruegel, N. Miosge +4 more
2010Fibrogenesis & Tissue Repair55 citations Open access
Semantic Scholar
Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis
T. Trinh-Minh, Chih-Wei Chen, C. Tran-Manh, Yi-Nan Li +20 more
2024Journal of Clinical Investigation49 citations Open access
Semantic Scholar
Col6a1 Null Mice as a Model to Study Skin Phenotypes in Patients with Collagen VI Related Myopathies: Expression of Classical and Novel Collagen VI Variants during Wound Healing
Sandra Lettmann, W. Bloch, Tobias Maaß, A. Niehoff +6 more
2014PLoS ONE49 citations Open access
Semantic Scholar
Controlling the Balance of Fibroblast Proliferation and Differentiation: Impact of Thy-1.
M. Schmidt, Danny Gutknecht, J. Simon, Jan-Niklas Schulz +3 more
2015Journal of Investigative Dermatology47 citations Open access
Semantic Scholar
Proplatelet formation is selectively inhibited by collagen type I through Syk-independent GPVI signaling
D. Semeniak, Rebecca Kulawig, D. Stegner, Imke Meyer +5 more
2016Journal of Cell Science43 citations Open access
Semantic Scholar
Ablation of integrin-mediated cell–collagen communication alleviates fibrosis
M. Sawant, Fang Wang, J. Koester, A. Niehoff +7 more
2023Annals of the Rheumatic Diseases42 citations Open access
Semantic Scholar
Signaling pathways affected by mutations causing osteogenesis imperfecta.
J. Etich, Mirko Rehberg, B. Eckes, G. Sengle +2 more
2020Cellular Signalling42 citations
Semantic Scholar
Molecular and cellular basis of scleroderma
B. Eckes, P. Moinzadeh, G. Sengle, N. Hunzelmann +1 more
2014Journal of molecular medicine42 citations
Semantic Scholar
Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model.
A. Stegemann, A. Sindrilaru, B. Eckes, Adriana del Rey +8 more
2013Arthritis & Rheumatism41 citations
Semantic Scholar
Biomarkers for skin involvement and fibrotic activity in scleroderma
P. Moinzadeh, C. Denton, D. Abraham, V. Ong +3 more
2012Journal of the European Academy of Dermatology and Venereology41 citations
Semantic Scholar
A small-molecule inhibitor of integrin α2β1 introduces a new strategy for antithrombotic therapy
L. Nissinen, O. Pentikäinen, A. Jouppila, J. Käpylä +9 more
2009Thrombosis and Haemostasis41 citations
Semantic Scholar
Collagen XXIII, Novel Ligand for Integrin α2β1 in the Epidermis*
G. Veit, Daniela Zwolanek, B. Eckes, S. Niland +7 more
2011Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Laminin α5 in the keratinocyte basement membrane is required for epidermal-dermal intercommunication.
J. Wegner, K. Loser, Gunita Apsite, R. Nischt +4 more
2016Matrix Biology36 citations
Semantic Scholar
Age-related bone deterioration is diminished by disrupted collagen sensing in integrin α2β1 deficient mice.
R. Stange, D. Kronenberg, M. Timmen, J. Everding +7 more
2013Bone33 citations
Semantic Scholar
Biofunctionalization of a generic collagenous triple helix with the α2β1 integrin binding site allows molecular force measurements.
S. Niland, C. Westerhausen, Stefan W. Schneider, B. Eckes +2 more
2011International Journal of Biochemistry and Cell Biology30 citations Open access
Semantic Scholar
CD49b‐dependent establishment of T helper cell memory
A. Hanazawa, Koji Hayashizaki, K. Shinoda, H. Yagita +9 more
2013Immunology and Cell Biology29 citations
Semantic Scholar
Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity.
Benjamin P. Woodall, A. Nyström, Rex A. Iozzo, J. Eble +5 more
2008Journal of Biological Chemistry29 citations
Semantic Scholar
The Dermatan Sulfate Proteoglycan Decorin Modulates α2β1 Integrin and the Vimentin Intermediate Filament System during Collagen Synthesis
O. Jungmann, Katerina Nikolovska, C. Stock, Jan-Niklas Schulz +5 more
2012PLoS ONE28 citations Open access
Semantic Scholar
Role of Integrins α1β1 and α2β1 in Wound and Tumor Angiogenesis in Mice.
S. Ghatak, S. Niland, Jan-Niklas Schulz, Fang Wang +6 more
2016American Journal of Pathology27 citations
Semantic Scholar
Dwarfism in Mice Lacking Collagen-binding Integrins α2β1 and α11β1 Is Caused by Severely Diminished IGF-1 Levels*
K. Blumbach, A. Niehoff, B. Belgardt, Harald W. A. Ehlen +8 more
2011Journal of Biological Chemistry27 citations Open access
Semantic Scholar
A story of fibers and stress: Matrix‐embedded signals for fibroblast activation in the skin
M. Sawant, B. Hinz, K. Schönborn, I. Zeinert +3 more
2021Wound Repair and Regeneration26 citations
Semantic Scholar
PECAM1+/Sca1+/CD38+ Vascular Cells Transform into Myofibroblast-Like Cells in Skin Wound Repair
J. Etich, V. Bergmeier, C. Frie, Sandra Kreft +10 more
2013PLoS ONE26 citations Open access
Semantic Scholar
Surface morphology and mechanical properties of fibroblasts from scleroderma patients
A. Reich, M. Meurer, B. Eckes, J. Friedrichs +1 more
2009Journal of Cellular and Molecular Medicine26 citations Open access
Semantic Scholar
TANGO1 inhibitors reduce collagen secretion and limit tissue scarring
I. Raote, A. Rosendahl, Hanna-Maria Häkkinen, Carina Vibe +26 more
2024Nature Communications22 citations Open access
Semantic Scholar
Fibroblast‐Derived TGFβ1 Regulates Skin Repair and Fibrosis
S. Willenborg, K. Schönborn, Mugdha Sawant, A. Bornikoel +5 more
2025Wound Repair and Regeneration21 citations Open access
Semantic Scholar

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T. Krieg×23
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T. Krieg — researcher profile on SciRah
Jan-Niklas Schulz×14
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Jan-Niklas Schulz — researcher profile on SciRah
K. Blumbach×7
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K. Blumbach — researcher profile on SciRah
A. Niehoff×7
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S. Eming — researcher profile on SciRah

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M. Paulsson — researcher profile on SciRah

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Julian Nüchel×5

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Julian Nüchel — researcher profile on SciRah

K. Schönborn×5

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K. Schönborn — researcher profile on SciRah

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M. Plomann — researcher profile on SciRah

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J. Eble — researcher profile on SciRah

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S. Niland — researcher profile on SciRah