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F. Kohlhapp · SciRah

Researcher profile · Semantic Scholar

F. Kohlhapp

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F. Kohlhapp — researcher profile on SciRah

h-index: 18
Works: 45
Citations: 3,432

Most-cited papers

Oncolytic viruses: a new class of immunotherapy drugs
H. Kaufman, F. Kohlhapp, A. Zloza
2015Nature reviews. Drug discovery1,548 citations Open access
Semantic Scholar
Molecular Pathways: Mechanism of Action for Talimogene Laherparepvec, a New Oncolytic Virus Immunotherapy
F. Kohlhapp, H. Kaufman
2015Clinical Cancer Research283 citations
Semantic Scholar
CD4+ T Cells
F. Kohlhapp, A. Zloza
2014206 citations
Semantic Scholar
microRNAs as mediators and communicators between cancer cells and the tumor micro-environment
F. Kohlhapp, A. Mitra, E. Lengyel, M. Peter
2015Oncogene191 citations Open access
Semantic Scholar
Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer
Jenna H. Newman, C. B. Chesson, Nora L Herzog, P. Bommareddy +44 more
2019Proceedings of the National Academy of Sciences of the United States of America174 citations Open access
Semantic Scholar
Oncolytic Viruses—Natural and Genetically Engineered Cancer Immunotherapies
Sachin R. Jhawar, Aditya Thandoni, P. Bommareddy, S. Hassan +5 more
2017Frontiers in Oncology154 citations Open access
Semantic Scholar
Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo
Jeffrey A. Mosenson, Andrew Zloza, J. Nieland, Elizabeth Garrett-Mayer +16 more
2013Science Translational Medicine149 citations Open access
Semantic Scholar
Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic Strategies.
B. Mai, Xiaoyu Lin, D. Albert, Leiming Li +21 more
2017Cancer Research100 citations Open access
Semantic Scholar
CD95 and CD95L promote and protect cancer stem cells
P. Ceppi, A. Hadji, F. Kohlhapp, A. Pattanayak +5 more
2014Nature Communications80 citations Open access
Semantic Scholar
Antigenic peptide nanofibers elicit adjuvant-free CD8⁺ T cell responses.
C. B. Chesson, E. Huelsmann, Andrew T. Lacek, F. Kohlhapp +4 more
2014Vaccine76 citations
Semantic Scholar
Venetoclax Increases Intratumoral Effector T Cells and Antitumor Efﬁ cacy in Combination with Immune Checkpoint Blockade
F. Kohlhapp, Dipica Haribhai, R. Mathew, Ryan Duggan +21 more
202071 citations
Semantic Scholar
NKG2D signaling on CD8+ T cells represses T-bet and rescues CD4-unhelped CD8+ T cell memory recall but not effector responses
A. Zloza, F. Kohlhapp, G. Lyons, J. Schenkel +14 more
2012Nature Medicine67 citations Open access
Semantic Scholar
NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade
F. Kohlhapp, Joseph R. Broucek, T. Hughes, E. Huelsmann +15 more
2015Journal of Immunotherapy for Cancer64 citations Open access
Semantic Scholar
Enhancing the Magnitude of Antibody Responses through Biomaterial Stereochemistry.
Rajagopal Appavu, C. B. Chesson, Alexey Y. Koyfman, Joshua D Snook +3 more
2015ACS Biomaterials Science & Engineering55 citations
Semantic Scholar
Venetoclax increases intra-tumoral effector T cells and anti-tumor efficacy in combination with immune checkpoint blockade.
F. Kohlhapp, Dipica Haribhai, R. Mathew, Ryan Duggan +20 more
2020Cancer Discovery50 citations
Semantic Scholar
Non-oncogenic acute viral infections disrupt anti-cancer responses and lead to accelerated cancer-specific host death
F. Kohlhapp, E. Huelsmann, Andrew T. Lacek, J. Schenkel +24 more
2016Cell Reports29 citations Open access
Semantic Scholar
Engagement of NK receptor NKG2D, but not 2B4, results in self-reactive CD8+T cells and autoimmune vitiligo
A. Zloza, G. Lyons, Lukasz K. Chlewicki, F. Kohlhapp +6 more
2011Autoimmunity22 citations
Semantic Scholar
Development of Tumor-infiltrating CD8+ T cell Memory Precursor Effector Cells (MPECs) and Anti-melanoma Memory Responses are the Result of Vaccination and TGF-β Blockade During the Perioperative Period of Tumor Resection
E. Bellavance, F. Kohlhapp, A. Zloza, Jeremy A. O'Sullivan +5 more
2011Journal of Immunology20 citations Open access
Semantic Scholar
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
C. Ager, M. Reilley, C. Nicholas, Todd Bartkowiak +496 more
2016Journal for ImmunoTherapy of Cancer18 citations Open access
Semantic Scholar
CD8 Co-receptor promotes susceptibility of CD8+ T cells to transforming growth factor-β (TGF-β)-mediated suppression
A. Zloza, Michael C. Jagoda, G. Lyons, Michael Graves +5 more
2010Cancer Immunology and Immunotherapy14 citations Open access
Semantic Scholar
The BCL-2-Selective Inhibitor Venetoclax Spares Activated T-Cells during Anti-Tumor Immunity
R. Mathew, Dipica Haribhai, F. Kohlhapp, Ryan Duggan +9 more
2018Blood12 citations
Semantic Scholar
Low-dose interleukin-2 impairs host anti-tumor immunity and inhibits therapeutic responses in a mouse model of melanoma
A. Zloza, N. Dharmadhikari, E. Huelsmann, Joseph R. Broucek +3 more
2016Cancer Immunology and Immunotherapy11 citations
Semantic Scholar
CD8+ T cells Sabotage their own Memory Potential through IFN-γ-dependent modification of the IL-12/IL-15Rα axis on Dendritic Cells
F. Kohlhapp, A. Zloza, Jeremy A. O'Sullivan, Tamson V. Moore +5 more
2012Journal of Immunology10 citations Open access
Semantic Scholar
NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells
F. Kohlhapp, Jeremy A. O'Sullivan, Tamson V. Moore, A. Zloza +1 more
2023Molecular Immunology8 citations Open access
Semantic Scholar
Priming with very low-affinity peptide ligands gives rise to CD8+ T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression
Jeremy A. O'Sullivan, A. Zloza, F. Kohlhapp, Tamson V. Moore +3 more
2011Cancer Immunology and Immunotherapy8 citations Open access
Semantic Scholar
Memory Precursors and Short-Lived Effector T cell Subsets Have Different Sensitivities to TGFβ
Jeremy A. O'Sullivan, F. Kohlhapp, A. Zloza, Lourdes Plaza-Rojas +3 more
2023International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Therapeutic NKG2D Ligation Facilitates Improved Wound Healing
J. Schenkel, J. Kubasiak, Hubert Dolubzino, F. Kohlhapp +4 more
2017Journal of Immunology5 citations
Semantic Scholar
Gut Microbial Shifts Indicate Melanoma Presence and Bacterial Interactions in a Murine Model
M. Rossi, Salvatore M. Aspromonte, F. Kohlhapp, Jenna H. Newman +9 more
2022Diagnostics4 citations Open access
Semantic Scholar
Single-step nanoparticle antigen presentation system for tumor immunotherapy
F. Kohlhapp, E. Huelsmann, J. Rudra, Arman Nabatiyan +1 more
2015Journal of Immunotherapy for Cancer2 citations Open access
Semantic Scholar
NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with CTLA-4 blockade and IL-2 (TUM2P.1039)
F. Kohlhapp, Joseph R. Broucek, T. Hughes, E. Huelsmann +2 more
2015Journal of Immunology1 citations
Semantic Scholar
Combination immunotherapy with anti-CTLA-4 and interleukin-2 redirects regulatory T cells into tumor-draining lymph nodes and expands anti-tumor CD8+ T cells in the tumor microenvironment
Joseph R. Broucek, T. Hughes, E. Huelsmann, Eugene Lusciks +7 more
2014Journal of Immunotherapy for Cancer1 citations Open access
Semantic Scholar
Magnesium alterations of graft immune cells (MAGIC).
Ramy Sedhom, A. Zloza, F. Kohlhapp, D. Medina +1 more
20170 citations
Semantic Scholar
Acute viral infection results in a PD-1-dependent loss of anti-tumor CD8+ T cell responses: implications for tumor immunotherapy
F. Kohlhapp, E. Huelsmann, Joseph R. Broucek, J. Schenkel +2 more
2015Journal of Immunotherapy for Cancer0 citations Open access
Semantic Scholar
Combination immunotherapy utilizing influenza infection and PD-1 blockade reduces lung melanoma tumor growth (TUM2P.1011)
A. Zloza, Joseph R. Broucek, R. Redondo, Janet P Zayas +5 more
2015Journal of Immunology0 citations
Semantic Scholar
Mosenson Mutant HSP 70 Reverses Autoimmune Depigmentation in Vitiligo
Jeffrey A. Mosenson, A. Zloza, J. Nieland, Elizabeth Garrett-Mayer +16 more
20130 citations
Semantic Scholar
Mutant HSP70i prevents effector T cell responses in autoimmune vitiligo (P4352)
Jeffrey A. Mosenson, A. Zloza, J. Nieland, Elizabeth Garrett-Mayer +16 more
2013Journal of Immunology0 citations
Semantic Scholar
Modification of the IL-12 / IL-15 Receptor Dependent − γ Potential through IFN-T Cells Sabotage Their Own Memory + CD 8
F. Kohlhapp, A. Zloza, Jeremy A. O'Sullivan, Tamson V. Moore +5 more
20120 citations
Semantic Scholar
CD8+ T cell effector differentiation and memory formation during vaccination under physiological and pathophysiological conditions
F. Kohlhapp
20120 citations
Semantic Scholar
Resection during the Perioperative Period of Tumor Blockade β Result of Vaccination and TGF-Antimelanoma Memory Responses Are the Cell Memory Precursor Effector Cells and T + Development of Tumor-Infiltrating CD 8
Guevara-Patino, Jagoda, Andrew T. Lacek, M. Posner +7 more
20110 citations
Semantic Scholar
NKG2D signaling on CD8+ T cells represses T-bet and rescues CD4-unhelped CD8+ T cell memory recall but not effector responses (52.12)
J. Guevara-Patiño, A. Zloza, G. Lyons, F. Kohlhapp +5 more
2011Journal of Immunology0 citations
Semantic Scholar
Priming with very low affinity peptide ligands gives rise to CD8+ T cell effectors with enhanced function but with greater susceptibility to TGF{beta}-mediated suppression
José A. Guevara-Patiño, Jeremy A. O'Sullivan, A. Zloza, F. Kohlhapp +3 more
20110 citations
Semantic Scholar
CD8+ T cells adversely effect their own memory potential via the regulation of the IL-12/IL-15R{alpha} axis
F. Kohlhapp, A. Zloza, J. Mccracken, Jeremy A. O'Sullivan +3 more
20110 citations
Semantic Scholar
NKG2D signaling on CD8+ T cells represses T-bet and rescues CD4-unhelped CD8+ T cell memory recall but not effector responses
J. Guevara-Patiño, A. Zloza, G. Lyons, F. Kohlhapp +5 more
20110 citations
Semantic Scholar
Priming with very low affinity peptide ligands gives rise to CD8+ T cell effectors with enhanced function but with greater susceptibility to TGFβ-mediated suppression (63.15)
J. Guevara-Patiño, Jeremy A. O'Sullivan, A. Zloza, F. Kohlhapp +3 more
2011Journal of Immunology0 citations
Semantic Scholar
CD8+ T cells adversely effect their own memory potential via the regulation of the IL-12/IL-15Rα axis (52.32)
F. Kohlhapp, A. Zloza, J. Mccracken, Jeremy A. O'Sullivan +3 more
2011Journal of Immunology0 citations
Semantic Scholar

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