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A. Essilfie · SciRah

Researcher profile · Semantic Scholar

A. Essilfie

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A. Essilfie — researcher profile on SciRah

h-index: 20
Works: 56
Citations: 1,968

Most-cited papers

Role for NLRP3 Inflammasome‐mediated, IL‐1&bgr;‐Dependent Responses in Severe, Steroid‐Resistant Asthma
R. Kim, J. Pinkerton, A. Essilfie, A. Robertson +16 more
2017American Journal of Respiratory and Critical Care Medicine400 citations
Semantic Scholar
MicroRNA‐21 drives severe, steroid‐insensitive experimental asthma by amplifying phosphoinositide 3‐kinase–mediated suppression of histone deacetylase 2
R. Kim, J. Horvat, J. Pinkerton, M. Starkey +14 more
2017Journal of Allergy and Clinical Immunology195 citations Open access
Semantic Scholar
Haemophilus influenzae Infection Drives IL-17-Mediated Neutrophilic Allergic Airways Disease
A. Essilfie, J. Simpson, J. Horvat, Julie A. Preston +4 more
2011PLoS Pathogens173 citations Open access
Semantic Scholar
Combined Haemophilus influenzae respiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma
A. Essilfie, J. Simpson, M. Dunkley, L. C. Morgan +4 more
2012Thorax160 citations Open access
Semantic Scholar
Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma
A. Essilfie, J. Horvat, R. Kim, J. Mayall +7 more
2015Thorax135 citations Open access
Semantic Scholar
Th2 cytokine antagonists: potential treatments for severe asthma
P. Hansbro, G. Scott, A. Essilfie, R. Kim +7 more
2013Expert Opinion on Investigational Drugs90 citations
Semantic Scholar
Inhibition of allergic airways disease by immunomodulatory therapy with whole killed Streptococcus pneumoniae.
Julie A. Preston, A. Essilfie, J. Horvat, Margaret A Wade +4 more
2007Vaccine84 citations
Semantic Scholar
Antagonism of miR-328 Increases the Antimicrobial Function of Macrophages and Neutrophils and Rapid Clearance of Non-typeable Haemophilus Influenzae (NTHi) from Infected Lung
Hock L. Tay, G. Kaiko, M. Plank, Jing-Jing Li +7 more
2015PLoS Pathogens74 citations Open access
Semantic Scholar
Nontypeable Haemophilus influenzae Induces Sustained Lung Oxidative Stress and Protease Expression
P. King, Rolee Sharma, K. O'Sullivan, S. Selemidis +18 more
2015PLoS ONE73 citations Open access
Semantic Scholar
COPD is characterized by increased detection of Haemophilus influenzae, Streptococcus pneumoniae and a deficiency of Bacillus species
J. Simpson, K. Baines, Jay C. Horvat, A. Essilfie +5 more
2016Respirology (Carlton South. Print)65 citations
Semantic Scholar
Murine models of infectious exacerbations of airway inflammation.
M. Starkey, A. Jarnicki, A. Essilfie, S. Gellatly +5 more
2013Current opinion in pharmacology (Print)63 citations
Semantic Scholar
Constitutive production of IL-13 promotes early-life Chlamydia respiratory infection and allergic airway disease
M. Starkey, A. Essilfie, J. Horvat, R. Kim +5 more
2012Mucosal Immunology61 citations Open access
Semantic Scholar
Activation of Olfactory Receptors on Mouse Pulmonary Macrophages Promotes Monocyte Chemotactic Protein-1 Production
Jing-Jing Li, Hock L. Tay, M. Plank, A. Essilfie +3 more
2013PLoS ONE54 citations Open access
Semantic Scholar
The inhibitor of semicarbazide‐sensitive amine oxidase, PXS‐4728A, ameliorates key features of chronic obstructive pulmonary disease in a mouse model
A. G. Jarnicki, H. Schilter, G. Liu, K. Wheeldon +5 more
2016British Journal of Pharmacology38 citations Open access
Semantic Scholar
Chlamydia muridarum Lung Infection in Infants Alters Hematopoietic Cells to Promote Allergic Airway Disease in Mice
M. Starkey, R. Kim, E. Beckett, H. Schilter +8 more
2012PLoS ONE36 citations Open access
Semantic Scholar
A Novel, Molybdenum-Containing Methionine Sulfoxide Reductase Supports Survival of Haemophilus influenzae in an In vivo Model of Infection
R. Dhouib, Dk Seti Maimonah Pg Othman, Victor Lin, Xuan Lai +8 more
2016Frontiers in Microbiology34 citations Open access
Semantic Scholar
Increased susceptibility of cystic fibrosis airway epithelial cells to ferroptosis
P. Maniam, A. Essilfie, M. Kalimutho, D. Ling +4 more
2021Biological Research27 citations Open access
Semantic Scholar
Time‐resolved proteomic profiling of cigarette smoke‐induced experimental chronic obstructive pulmonary disease
D. Skerrett‐Byrne, E. Bromfield, H. Murray, M Fairuz B Jamaluddin +12 more
2021Respirology (Carlton South. Print)22 citations Open access
Semantic Scholar
Programmed Death Ligand 1 Promotes Early-Life Chlamydia Respiratory Infection-Induced Severe Allergic Airway Disease.
M. Starkey, Duc H. Nguyen, Alexandra C. Brown, A. Essilfie +4 more
2016American Journal of Respiratory Cell and Molecular Biology21 citations
Semantic Scholar
Peptide methionine sulfoxide reductase from Haemophilus influenzae is required for protection against HOCl and affects the host response to infection.
M. Nasreen, R. Dhouib, Jennifer Hosmer, Hewa G S Wijesinghe +6 more
2020ACS Infectious Diseases20 citations
Semantic Scholar
Access to highly specialized growth substrates and production of epithelial immunomodulatory metabolites determine survival of Haemophilus influenzae in human airway epithelial cells
Jennifer Hosmer, M. Nasreen, R. Dhouib, A. Essilfie +6 more
2022PLoS Pathogens19 citations Open access
Semantic Scholar
The DmsABC Sulfoxide Reductase Supports Virulence in Non-typeable Haemophilus influenzae
R. Dhouib, M. Nasreen, Dk Seti Maimonah Pg Othman, Daniel Ellis +5 more
2021Frontiers in Microbiology18 citations Open access
Semantic Scholar
Altered lung function at mid-adulthood in mice following neonatal exposure to hyperoxia.
Foula Sozo, J. Horvat, A. Essilfie, M. O'Reilly +2 more
2015Respiratory Physiology & Neurobiology15 citations
Semantic Scholar
Maturation of molybdoenzymes and its influence on the pathogenesis of non-typeable Haemophilus influenzae
R. Dhouib, Dk S. M. Pg Othman, A. Essilfie, P. Hansbro +3 more
2015Frontiers in Microbiology15 citations Open access
Semantic Scholar
The Alternative Sigma Factor RpoE2 Is Involved in the Stress Response to Hypochlorite and in vivo Survival of Haemophilus influenzae
M. Nasreen, Aidan Fletcher, Jennifer Hosmer, Qi-Feng Zhong +3 more
2021Frontiers in Microbiology14 citations Open access
Semantic Scholar
Investigating the Links between Lower Iron Status in Pregnancy and Respiratory Disease in Offspring Using Murine Models
H. Gomez, A. Pillar, Alexandra C. Brown, R. Kim +14 more
2021Nutrients9 citations Open access
Semantic Scholar
The DmsABC S-oxide reductase is an essential component of a novel, hypochlorite-inducible system of extracellular stress defense in Haemophilus influenzae
M. Nasreen, Daniel Ellis, Jennifer Hosmer, A. Essilfie +4 more
2024Frontiers in Microbiology8 citations Open access
Semantic Scholar
A novel SSAO inhibitor PXS-4728 A suppresses inflammation and fibrosis and improves lung function in experimental chronic obstructive pulmonary disease
A. Jarnicki, H. Schilter, G. Liu, K. Wheeldon +5 more
20168 citations
Semantic Scholar
Anti‐protease levels in cystic fibrosis are associated with lung function, recovery from pulmonary exacerbations and may be gender‐related
A. Essilfie, Neralee Houston, P. Maniam, G. Hartel +2 more
2023Respirology (Carlton South. Print)7 citations Open access
Semantic Scholar
Correction: Antagonism of miR-328 Increases the Antimicrobial Function of Macrophages and Neutrophils and Rapid Clearance of Non-typeable Haemophilus Influenzae (NTHi) from Infected Lung
Hock L. Tay, G. Kaiko, M. Plank, Jing-Jing Li +7 more
2015PLoS Pathogens6 citations Open access
Semantic Scholar
Cissampelos sympodialis and Warifteine Suppress Anxiety-Like Symptoms and Allergic Airway Inflammation in Acute Murine Asthma Model
C. Bezerra-Santos, E. Bondarenko, A. Essilfie, P. Nair +5 more
2020Revista Brasileira de Farmacognosia5 citations
Semantic Scholar
MicroRNA-21 drives severe , steroid-insensitive experimental asthma by amplifying 1 PI 3 K-mediated suppression of HDAC 2 2 3
R. Kim, J. Horvat, J. Pinkerton, R. Starkey +13 more
20164 citations
Semantic Scholar
Dietary Iron Intake Impacts the Microbial Composition of the Murine Intestinal and Lung Microbiome
A. Essilfie, Alison Smith, Rebecca L. Watts, Pramila Maniam +4 more
2025Nutrients3 citations Open access
Semantic Scholar
Crucial role of iron metabolism in determining outcomes of influenza A virus infection and disease
J. Mayall, A. Pillar, K. Daly, A. Brown +13 more
202210.01 - Respiratory infections and bronchiectasis3 citations
Semantic Scholar
PD-L1 promotes early-life chlamydia respiratory infection-induced severe allergic airway disease
M. Starkey, Duc H. Nguyen, Alexandra C. Brown, A. Essilfie +4 more
20163 citations
Semantic Scholar
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying PI3K-mediated suppression of HDAC2 (HYP7P.262)
P. Hansbro, R. Kim, J. Pinkerton, M. Starkey +9 more
2015Journal of Immunology3 citations
Semantic Scholar
Crucial role for iron metabolism in mediating influenza A virus infection and associated disease
A. Pillar, Katie Daly, Henry M. Gomez, A. Essilfie +20 more
2025bioRxiv1 citations Open access
Semantic Scholar
Increased susceptibility of cystic fibrosis airway epithelial cells to ferroptosis
P. Maniam, A. Essilfie, M. Kalimutho, D. Ling +4 more
2021Biological Research1 citations Open access
Semantic Scholar
Molecular and Proteomic Approach to Investigate Abnormal Iron Homeostasis in the Cystic Fibrosis Airway
P. Maniam, Xia-Hui Tan, A. Essilfie, G. Anderson +4 more
20171 citations
Semantic Scholar
Investigating antioxidant therapy for steroid-resistant asthma
J. Pinkerton, R. Kim, A. Essilfie, B. Rae +7 more
20161 citations
Semantic Scholar
Constitutive IL-13 promotes respiratory chlamydial infection and infection-induced chronic airway hyper-responsiveness (175.18)
M. Starkey, R. W. Kim, J. Horvat, A. Essilfie +4 more
2012Journal of Immunology1 citations
Semantic Scholar
Efficacy Of Antibiotic-Based Therapeutic Strategies For The Treatment Of Infection-Induced, Steroid-Resistant Allergic Airways Disease
P. Hansbro, J. Horvat, A. Essilfie, R. Kim +4 more
2012Asian Test Symposium1 citations
Semantic Scholar
Infection-Induced Neutrophilic Allergic Airways Disease Is Resistant To Steroid Treatment
P. Hansbro, J. Horvat, A. Essilfie, R. Kim +5 more
2011Asian Test Symposium1 citations
Semantic Scholar
Iron metabolism determines the outcome of influenza A virus infection
J. Mayall, A. Pillar, K. Daly, A. Brown +13 more
202310.01 - Respiratory infections and bronchiectasis0 citations
Semantic Scholar
LSC - 2023 - Iron metabolism determines the outcome of influenza A virus infection
J. Mayall, A. Pillar, K. Daly, Alexandra C. Brown +13 more
2023Respiratory infections and bronchiectasis0 citations
Semantic Scholar
Relationship between interleukin-13 and transferrin receptor-1 responses in the pathogenesis of asthma
A. Pillar, A. Brown, J. Mayall, J. Weaver +21 more
202205.03 - Allergy and immunology0 citations
Semantic Scholar
Cissampelos sympodialis and Warifteine Suppress Anxiety-Like Symptoms and Allergic Airway Inflammation in Acute Murine Asthma Model
C. Bezerra-Santos, E. Bondarenko, A. Essilfie, P. Nair +5 more
20200 citations
Semantic Scholar
INTERRELATIONSHIP BETWEEN MICRORNA-21, IL-1 beta AND SLC26A4 RESPONSES IN SEVERE ASTHMA
R. Kim, J. Horvat, J. Pinkerton, B. Rae +11 more
20190 citations
Semantic Scholar
Impaired induction of Slc26a4 promotes respiratory acidosis and severe, steroid-resistant asthma
R. Kim, J. Pinkerton, B. Rae, J. Mayall +9 more
2017Journal of Immunology0 citations
Semantic Scholar
NLRP3 inflammasome-mediated, IL-1β-dependent inflammatory responses drive steroid-resistant asthma
J. Horvat, R. Kim, J. Pinkerton, A. Essilfie +9 more
20160 citations
Semantic Scholar

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