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C. Saini · SciRah

Researcher profile · Semantic Scholar

C. Saini

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C. Saini — researcher profile on SciRah

h-index: 19
Works: 46
Citations: 1,185

Most-cited papers

Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice
Leena Sapra, Hamid Y. Dar, A. Bhardwaj, A. Pandey +9 more
2021Scientific Reports138 citations Open access
Semantic Scholar
Bifidobacterium longum Ameliorates Ovariectomy-Induced Bone Loss via Enhancing Anti-Osteoclastogenic and Immunomodulatory Potential of Regulatory B Cells (Bregs)
Leena Sapra, Niti Shokeen, Konica Porwal, C. Saini +7 more
2022Frontiers in Immunology94 citations Open access
Semantic Scholar
CD4+ Th17 Cells Discriminate Clinical Types and Constitute a Third Subset of Non Th1, Non Th2 T Cells in Human Leprosy
C. Saini, V. Ramesh, I. Nath
2013PLoS Neglected Tropical Diseases91 citations Open access
Semantic Scholar
Immunology of leprosy and diagnostic challenges.
I. Nath, C. Saini, V. Valluri
2015Clinical Dermatology83 citations
Semantic Scholar
Leprosy Reactions Show Increased Th17 Cell Activity and Reduced FOXP3+ Tregs with Concomitant Decrease in TGF-β and Increase in IL-6
C. Saini, A. Siddiqui, V. Ramesh, I. Nath
2016PLoS Neglected Tropical Diseases81 citations Open access
Semantic Scholar
Increase in TGF-β Secreting CD4+CD25+ FOXP3+ T Regulatory Cells in Anergic Lepromatous Leprosy Patients
C. Saini, V. Ramesh, I. Nath
2014PLoS Neglected Tropical Diseases64 citations Open access
Semantic Scholar
Interleukin-10 Producing Regulatory B Cells Transformed CD4+CD25− Into Tregs and Enhanced Regulatory T Cells Function in Human Leprosy
M. Tarique, H. Naz, Santosh Kurra, C. Saini +6 more
2018Frontiers in Immunology63 citations Open access
Semantic Scholar
Bacillus coagulans ameliorates inflammatory bone loss in post-menopausal osteoporosis via modulating the “Gut-Immune-Bone” axis
Leena Sapra, C. Saini, P. K. Mishra, B. Garg +3 more
2025Gut microbes53 citations Open access
Semantic Scholar
COVID-19: Immunology, Immunopathogenesis and Potential Therapies
A. Bhardwaj, Leena Sapra, C. Saini, Zaffar Azam +4 more
2021International Reviews of Immunology53 citations Open access
Semantic Scholar
Long-term implications of COVID-19 on bone health: pathophysiology and therapeutics
Leena Sapra, C. Saini, B. Garg, Ranjan Gupta +3 more
2022Inflammation Research50 citations Open access
Semantic Scholar
T helper cells in leprosy: An update.
C. Saini, M. Tarique, Reeta Rai, A. Siddiqui +2 more
2017Immunology Letters44 citations
Semantic Scholar
Differential expression of programmed death 1 (PD-1) on various immune cells and its role in human leprosy
Mohammad Tarique, H. Naz, Mohd Suhail, A. Turan +7 more
2023Frontiers in Immunology43 citations Open access
Semantic Scholar
Increased IL‐35 producing Tregs and CD19+IL‐35+ cells are associated with disease progression in leprosy patients
M. Tarique, C. Saini, R. Naqvi, N. Khanna +1 more
2017Cytokine32 citations
Semantic Scholar
IL‐12 and IL‐23 modulate plasticity of FoxP3+ regulatory T cells in human Leprosy
M. Tarique, C. Saini, R. Naqvi, N. Khanna +2 more
2017Molecular Immunology31 citations
Semantic Scholar
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System
Zaffar Azam, Leena Sapra, Kalpana Baghel, N. Sinha +5 more
2023Cells25 citations Open access
Semantic Scholar
“Immunoporosis”: Immunology of Osteoporosis
Leena Sapra, Zaffar Azam, L. Rani, C. Saini +5 more
2021Proceedings of the National Academy of Sciences, India, Section B: biological sciences22 citations
Semantic Scholar
Elevated IL-6R on CD4+ T cells promotes IL-6 driven Th17 cell responses in patients with T1R leprosy reactions
C. Saini, R. Srivastava, M. Tarique, Santosh Kurra +3 more
2020Scientific Reports22 citations Open access
Semantic Scholar
Lactobacillus rhamnosus (LR) ameliorates pulmonary and extrapulmonary acute respiratory distress syndrome (ARDS) via targeting neutrophils.
Leena Sapra, C. Saini, Sneha Das, P. K. Mishra +4 more
2023Clinical Immunology20 citations Open access
Semantic Scholar
γδ T cells are associated with inflammation and immunopathogenesis of leprosy reactions.
C. Saini, M. Tarique, V. Ramesh, N. Khanna +1 more
2018Immunology Letters20 citations
Semantic Scholar
Targeting the osteoclastogenic cytokine IL-9 as a novel immunotherapeutic strategy in mitigating inflammatory bone loss in post-menopausal osteoporosis
Leena Sapra, C. Saini, Shivani Sharma, Dibyani Nanda +8 more
2024JBMR Plus19 citations
Semantic Scholar
Regulatory T cells antagonize proinflammatory response of IL-17 during cutaneous tuberculosis
C. Saini, Praveen Kumar, M. Tarique, Alpana Sharma +1 more
2018Journal of Inflammation Research17 citations Open access
Semantic Scholar
Fate of T Cells and their Secretory Proteins During the Progression of Leprosy.
M. Tarique, C. Saini, H. Naz, R. Naqvi +2 more
2017Current protein and peptide science16 citations
Semantic Scholar
Association of IL-10 Gene Polymorphism With IL-10 Secretion by CD4 and T Regulatory Cells in Human Leprosy
Mohammad Tarique, H. Naz, C. Saini, Mohd Suhail +3 more
2020Frontiers in Immunology15 citations Open access
Semantic Scholar
Where do T cell subsets stand in SARS-CoV-2 infection: an update
Mohammad Tarique, Mohd Suhail, H. Naz, Naoshad Muhammad +7 more
2022Frontiers in Cellular and Infection Microbiology14 citations Open access
Semantic Scholar
A distinct double positive IL-17A+/F+ T helper 17 cells induced inflammation leads to IL17 producing neutrophils in Type 1 reaction of leprosy patients.
C. Saini, R. Srivastava, Praveen Kumar, V. Ramesh +1 more
2020Cytokine14 citations
Semantic Scholar
Dysregulated Th17/Treg cell axis is correlated with local and systemic immune response in human intermediate uveitis.
C. Saini, Leena Sapra, Prabhav Puri, Pradyuman K Mishra +2 more
2024Immunology Letters13 citations
Semantic Scholar
Lsr2 of Mycobacterium leprae and Its Synthetic Peptides Elicit Restitution of T Cell Responses in Erythema Nodosum Leprosum and Reversal Reactions in Patients with Lepromatous Leprosy
C. Saini, H. K. Prasad, R. Rani, A. Murtaza +3 more
2013Clinical and Vaccine Immunology13 citations Open access
Semantic Scholar
Compromised anti-osteoclastogenic and immunomodulatory functions of regulatory B cells (Bregs) aggravate inflammatory bone loss in post-menopausal osteoporosis.
Leena Sapra, C. Saini, P. K. Mishra, B. Garg +2 more
2025Biochimica et Biophysica Acta - Molecular Basis of Disease12 citations Open access
Semantic Scholar
IL-21 plays an important role in modulating "Th17-Treg" cell axis in leprosy Type 1 reactions.
C. Saini, Leena Sapra, A. Bhardwaj, M. Tarique +5 more
2022Cytokine11 citations
Semantic Scholar
Role of FoxP3 + Treg Cells Mediating Immune Suppression in Leprosy
C. Saini, M. Tarique, Sudhir Kumar, D. N. Rao
20146 citations
Semantic Scholar
Lactobacillus acidophilus Ameliorates Inflammatory Bone Loss Under Postmenopausal Osteoporotic Conditions via Modulating the Gut‐Resident RORγT− pTreg Cell Population
A. Bhardwaj, Leena Sapra, C. Saini, Abhay Tiwari +3 more
2025Journal of Cellular Physiology5 citations
Semantic Scholar
Role of Regulatory T Lymphocytes in Health and Disease
Niti Shokeen, C. Saini, Leena Sapra, Zaffar Azam +3 more
20204 citations
Semantic Scholar
Deoxycholic acid (DCA) alleviates LPS-induced Inflammatory Bone Loss via modulating the “Gut-Bone” homeostasis
Sumedha Yadav, Swati Rajput, C. Saini, M. Sharma +2 more
2025bioRxiv3 citations Open access
Semantic Scholar
Immunology of human leprosy and diagnostic challenges
I. Nath, C. Saini, V. Valluri
20152 citations
Semantic Scholar
Double positive IL-17A+IFN-γ+CCR6+ ILCs contribute towards the immunopathology of lepromatous leprosy.
C. Saini, Leena Sapra, V. Ramesh, Poonam Puri +1 more
2025Immunology Letters1 citations
Semantic Scholar
Mitigating inflammatory bone loss in post-menopausal osteoporosis via targeting the IL-9 producing osteoclastogenic Th9 cells
Leena Sapra, C. Saini, P. K. Mishra, Naibedya Chattopadhya +1 more
2023bioRxiv1 citations Open access
Semantic Scholar
Bifidobacterium longum attenuates ovariectomy-induced bone loss via modulating the Immunoporotic “Breg-Treg-Th17” cell axis
Leena Sapra, Niti Shokeen, Konica Gupta, C. Saini +6 more
20221 citations Open access
Semantic Scholar
Gut-Associated Metabolites (GAMs) revitalize dysfunctional CD8⁺ T lymphocytes in Osteosarcoma
Leena Sapra, A. Bhardwaj, Ankush Paladhi, Aasia Farhat +6 more
2026bioRxiv0 citations Open access
Semantic Scholar
Vitamin D mitigates Inflammatory Bone Loss in Postmenopausal Osteoporosis via modulating the Gut-Immune-Bone axis
A. Bhardwaj, Leena Sapra, Tamanna Sharma, Swati Rajput +9 more
2026bioRxiv0 citations Open access
Semantic Scholar
Characterization of Circulating T Helper Cells in Post-tuberculosis Pulmonary Sequelae
G. Bade, A. Talwar, C. Saini, R. Srivastava +3 more
2025American Journal of Respiratory and Critical Care Medicine0 citations
Semantic Scholar
ILC3 inhibits Osteoclastogenesis and ameliorates Inflammatory Bone Loss in Post-menopausal Osteoporosis
A. Bhardwaj, Leena Sapra, Simran Preet Kaur, Tamanna Sharma +3 more
2025bioRxiv0 citations Open access
Semantic Scholar
Phenotypic characterization of Natural Killer Cells in Post Tuberculosis Pulmonary Sequelae
A. Talwar, G. Bade, R. Srivastava, K. Madan +2 more
2024Tuberculosis and non-tuberculous mycobacterial diseases0 citations
Semantic Scholar
Lactobacillus rhamnosus (LR) ameliorates acute respiratory distress syndrome (ARDS) via modulating the lung “Innate Lymphoid Cells (ILCs)-Mononuclear Phagocytic System (MPS)”
Leena Sapra, Sneha Das, C. Saini, P. Mishra +2 more
2023bioRxiv0 citations Open access
Semantic Scholar
DYSREGULATED ILC3S-ILCREGS AXIS IN TYPE 1 REACTIONS (T1R) OF LEPROSY
C. Saini, Lokesh Sapra, A. Bhardwaj, M. Tarique +4 more
2023International Journal of Infectious Diseases0 citations Open access
Semantic Scholar
IL-6 promotes pathogenic Th17 in T1R leprosy reactions by stimulating Il17 producing by IL-6R pathway
C. Saini, R. Srivastava, N. Khanna, V. Ramesh +1 more
20200 citations Open access
Semantic Scholar
Scattergram of IL-17A, IL-17C, IL-17D and IL-17F expression (Mean ΔCt ± SD) in both antigen stimulated PBMC and skin lesions of BT, LL and HC subjects.
C. Saini, V. Ramesh, I. Nath
20130 citations Open access
Semantic Scholar

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