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Patrizia Borsotti · SciRah

Researcher profile · Semantic Scholar

Patrizia Borsotti

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Patrizia Borsotti — researcher profile on SciRah

h-index: 27
Works: 44
Citations: 3,549

Most-cited papers

The microtubule-affecting drug paclitaxel has antiangiogenic activity.
D. Belotti, V. Vergani, T. Drudis, Patrizia Borsotti +4 more
1996Clinical Cancer Research688 citations
Semantic Scholar
Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells.
G. Taraboletti, S. D'Ascenzo, Patrizia Borsotti, R. Giavazzi +2 more
2002American Journal of Pathology605 citations Open access
Semantic Scholar
Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.
D. Salani, G. Taraboletti, Laura Rosano', V. di Castro +3 more
2000American Journal of Pathology345 citations Open access
Semantic Scholar
Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases.
G. Taraboletti, A. Garofalo, D. Belotti, T. Drudis +4 more
1995Journal of the National Cancer Institute233 citations
Semantic Scholar
Bioavailability of VEGF in tumor-shed vesicles depends on vesicle burst induced by acidic pH.
G. Taraboletti, S. D'Ascenzo, I. Giusti, D. Marchetti +5 more
2006Neoplasia213 citations Open access
Semantic Scholar
Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4
M. Broggini, S. Marchini, E. Galliera, Patrizia Borsotti +7 more
2003Leukemia146 citations Open access
Semantic Scholar
Antiangiogenic Properties of 17-(Dimethylaminoethylamino)-17-Demethoxygeldanamycin
G. Kaur, D. Belotti, A. Burger, Kirsten Fisher-Nielson +6 more
2004Clinical Cancer Research136 citations Open access
Semantic Scholar
Vascular-targeting activity of ZD6126, a novel tubulin-binding agent.
Gianluca Micheletti, Maura Poli, Patrizia Borsotti, Michele Martinelli +3 more
2003Cancer Research117 citations
Semantic Scholar
BAY 12-9566, a novel inhibitor of matrix metalloproteinases with antiangiogenic activity.
Carmen Gatto, M. Rieppi, Patrizia Borsotti, Silvia Innocenti +6 more
1999Clinical Cancer Research116 citations
Semantic Scholar
The 140-kilodalton antiangiogenic fragment of thrombospondin-1 binds to basic fibroblast growth factor.
G. Taraboletti, D. Belotti, Patrizia Borsotti, V. Vergani +3 more
1997Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research99 citations
Semantic Scholar
Antiangiogenic activity of aplidine, a new agent of marine origin
G. Taraboletti, Maura Poli, R. Dossi, Luigi Manenti +6 more
2004British Journal of Cancer87 citations Open access
Semantic Scholar
Antiangiogenic and antitumor activity of IDN 5390, a new taxane derivative.
G. Taraboletti, Gianluca Micheletti, M. Rieppi, Maura Poli +10 more
2002Clinical Cancer Research66 citations
Semantic Scholar
Vascular disrupting activity of tubulin-binding 1,5-diaryl-1H-imidazoles.
Katiuscia Bonezzi, G. Taraboletti, Patrizia Borsotti, F. Bellina +2 more
2009Journal of Medicinal Chemistry63 citations Open access
Semantic Scholar
Antiangiogenic activity of trabectedin in myxoid liposarcoma: Involvement of host TIMP‐1 and TIMP‐2 and tumor thrombospondin‐1
R. Dossi, R. Frapolli, S. di Giandomenico, L. Paracchini +13 more
2014International Journal of Cancer60 citations Open access
Semantic Scholar
The Vascular Targeting Property of Paclitaxel Is Enhanced by SU6668, a Receptor Tyrosine Kinase Inhibitor, Causing Apoptosis of Endothelial Cells and Inhibition of Angiogenesis
E. Naumova, P. Ubezio, A. Garofalo, Patrizia Borsotti +6 more
2006Clinical Cancer Research58 citations Open access
Semantic Scholar
p73 overexpression increases VEGF and reduces thrombospondin-1 production: implications for tumor angiogenesis
F. Vikhanskaya, M. Bani, Patrizia Borsotti, C. Ghilardi +6 more
2001Oncogene57 citations Open access
Semantic Scholar
Thrombospondin‐1 inhibits Kaposi's sarcoma (KS) cell and HIV‐1 Tat‐induced angiogenesis and is poorly expressed in KS lesions
G. Taraboletti, R. Benelli, Patrizia Borsotti, M. Rusnati +4 more
1999Journal of Pathology54 citations Open access
Semantic Scholar
Thrombospondin‐1 is part of a Slug‐independent motility and metastatic program in cutaneous melanoma, in association with VEGFR‐1 and FGF‐2
Patrizia Borsotti, C. Ghilardi, P. Ostano, A. Silini +13 more
2015Pigment Cell & Melanoma Research53 citations Open access
Semantic Scholar
Posttranscriptional stimulation of endothelial cell matrix metalloproteinases 2 and 1 by endothelioma cells.
G. Taraboletti, Laura Sonzogni, V. Vergani, Ghamartaj Hosseini +10 more
2000Experimental Cell Research50 citations
Semantic Scholar
Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib
M. Zucchetti, Katiuscia Bonezzi, R. Frapolli, F. Sala +8 more
2013Cancer Chemotherapy and Pharmacology43 citations
Semantic Scholar
The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2)
M. Rusnati, Patrizia Borsotti, E. Moroni, C. Foglieni +12 more
2018Angiogenesis41 citations
Semantic Scholar
Inhibition of matrix metalloproteinases by over‐expression of tissue inhibitor of metalloproteinase‐2 inhibits the growth of experimental hemangiomas
V. Vergani, A. Garofalo, M. Bani, Patrizia Borsotti +7 more
2001International Journal of Cancer35 citations Open access
Semantic Scholar
Effect of all trans‐retinoic acid (ATRA) on the adhesive and motility properties of acute promyelocytic leukemia cells
G. Taraboletti, Patrizia Borsotti, R. Chirivi, V. Vergani +4 more
1997International Journal of Cancer33 citations Open access
Semantic Scholar
Antimetastatic and antiangiogenic activity of trabectedin in cutaneous melanoma
Laura Carminati, D. Pinessi, Patrizia Borsotti, L. Minoli +4 more
2019Carcinogenesis31 citations
Semantic Scholar
Potential Antagonism of Tubulin-Binding Anticancer Agents in Combination Therapies
G. Taraboletti, Gianluca Micheletti, R. Dossi, Patrizia Borsotti +4 more
2005Clinical Cancer Research31 citations Open access
Semantic Scholar
CCN-Based Therapeutic Peptides Modify Pancreatic Ductal Adenocarcinoma Microenvironment and Decrease Tumor Growth in Combination with Chemotherapy
A. Resovi, Patrizia Borsotti, T. Ceruti, A. Passoni +5 more
2020Cells30 citations Open access
Semantic Scholar
Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.
Katiuscia Bonezzi, D. Belotti, B. North, C. Ghilardi +7 more
2012Neoplasia30 citations Open access
Semantic Scholar
Fibronectin fragments generated by pancreatic trypsin act as endogenous inhibitors of pancreatic tumor growth
A. Resovi, Perla Persichitti, L. Brunelli, L. Minoli +13 more
2023Journal of experimental & clinical cancer research : CR10 citations Open access
Semantic Scholar
Expression of thrombospondin-1 by tumor cells in patient-derived ovarian carcinoma xenografts
D. Pinessi, P. Ostano, Patrizia Borsotti, E. Bello +7 more
2015Connective Tissue Research10 citations
Semantic Scholar
Tumor vascular remodeling by thrombospondin-1 enhances drug delivery and antineoplastic activity.
D. Pinessi, A. Resovi, F. Sangalli, L. Morosi +12 more
2021Matrix Biology7 citations
Semantic Scholar
The TGF-βR1 inhibitor galunisertib re-shapes the PDAC-TME by limiting decidual-like natural killer cells polarization
M. Cucchiara, M. Palano, Cristian Rubuano, Gianluca De Antoni +23 more
2026Cell Death and Disease4 citations Open access
Semantic Scholar
Hijacking client instability to selectively disrupt HSP90-driven glucocorticoid receptor activation.
E. Longhi, Andrea Magni, Luca Torielli, Giulia Lodigiani +11 more
2026Pharmacological Research4 citations Open access
Semantic Scholar
TSP-1 interaction with RANK and OPG: implications for bone remodeling and osteolytic bone metastasis
Laura Carminati, Fabio Sangalli, C. Urbinati, E. Longhi +6 more
2026Cell Death and Disease1 citations Open access
Semantic Scholar
Bone marrow–derived thrombospondin-1 programs tumor cell dormancy via CD47–integrin αvβ3 axis
Elena Carlessi, Patrizia Borsotti, Elena Morlacchi, E. Longhi +9 more
2026Cell Communication and Signaling0 citations Open access
Semantic Scholar
Editor's Note: Antiangiogenic Properties of 17-(Dimethylaminoethylamino)-17-Demethoxygeldanamycin: An Orally Bioavailable Heat Shock Protein 90 Modulator.
Gurmeet Kaur, D. Belotti, A. Burger, Kirsten Fisher-Nielson +6 more
2024Clinical Cancer Research0 citations
Semantic Scholar
PO-76 The T3R domain of thrombospondin-1 delays tumor growth and improves tumor response to chemotherapy by remodeling the tumor vasculature
D. Pinessi, A. Resovi, L. Morosi, Patrizia Borsotti +4 more
20210 citations
Semantic Scholar
Abstract 916: A novel LAP-IL2 fusion protein elicits efficacy as single agent in syngeneic renal and melanoma mouse models
M. Riveiro, R. Frapolli, G. Taraboletti, K. Rezai +6 more
2021Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 198: The T3R domain of thrombospondin-1 delays tumor growth and improves tumor response to chemotherapy by remodeling the tumor vasculature
D. Pinessi, A. Resovi, L. Morosi, Patrizia Borsotti +4 more
2019Tumor Biology0 citations Open access
Semantic Scholar
Role of the FGF-2-binding fragment of thrombospondin-1 (TSP-1) in tumor progression
A. Resovi, Patrizia Borsotti, S. Bonifacio, P. Oliva +3 more
20120 citations
Semantic Scholar
Inhibition of SIRT 2 Potentiates the Anti-motility Activity of Taxanes : Implications for Antineoplastic Combination Therapies 1 , 2
Katiuscia Bonezzi, D. Belotti, B. North, C. Ghilardi +7 more
20120 citations
Semantic Scholar
New vicinal diaryl-substituted imidazole derivatives with vascular disrupting activity
F. Bellina, S. Cauteruccio, Patrizia Borsotti, G. Taraboletti +3 more
20070 citations
Semantic Scholar
Vascular targeting activity of new tubulinj binding imidazole derivatives
Patrizia Borsotti, F. Bellina, S. Cauteruccio, G. Taraboletti +2 more
20060 citations
Semantic Scholar
28 ORAL Imidazole derivatives with vascular disrupting activity
F. Bellina, S. Cauteruccio, Patrizia Borsotti, G. Taraboletti +3 more
20060 citations
Semantic Scholar
Potential Antagonism ofTubulin-Binding Anticancer Agents in
GiuliaTaraboletti, GianlucaMicheletti, R. Dossi, Patrizia Borsotti +4 more
20050 citations
Semantic Scholar

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G. Taraboletti×39
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G. Taraboletti — researcher profile on SciRah
R. Giavazzi×36
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R. Giavazzi — researcher profile on SciRah
D. Belotti×14
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A. Resovi×10
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M. Bani — researcher profile on SciRah

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R. Dossi — researcher profile on SciRah

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T. Drudis — researcher profile on SciRah