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M. L. Cunningham · SciRah

Researcher profile · Semantic Scholar

M. L. Cunningham

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M. L. Cunningham — researcher profile on SciRah

h-index: 28
Works: 68
Citations: 3,403

Most-cited papers

Standardizing global gene expression analysis between laboratories and across platforms
T. Bammler, R. Beyer, S. Bhattacharya, G. Boorman +60 more
2005Nature Methods493 citations
Semantic Scholar
Modes of Action and Species-Specific Effects of Di-(2-ethylhexyl)Phthalate in the Liver
I. Rusyn, J. Peters, M. L. Cunningham
2006Critical Reviews in Toxicology281 citations Open access
Semantic Scholar
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study
J. Corton, M. L. Cunningham, B. Hummer, C. Lau +6 more
2014Critical Reviews in Toxicology225 citations
Semantic Scholar
Gene expression profiling of rat livers reveals indicators of potential adverse effects.
A. Heinloth, R. Irwin, G. Boorman, P. Nettesheim +11 more
2004Toxicological Sciences213 citations
Semantic Scholar
Metabolism: A Bottleneck in In Vitro Toxicological Test Development
S. Coecke, H. Ahr, B. Blaauboer, S. Bremer +34 more
2006Alternatives to laboratory animals : ATLA202 citations
Semantic Scholar
The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators.
E. Pacyniak, Xing-Guo Cheng, M. L. Cunningham, K. Crofton +2 more
2007Toxicological Sciences149 citations
Semantic Scholar
PHOTOSENSITIZED PRODUCTION OF SUPEROXIDE ANION BY MONOCHROMATIC (290–405 nm) ULTRAVIOLET IRRADIATION OF NADH and NADPH COENZYMES
M. L. Cunningham, Jennifer S. Johnson, Susan M. Giovanazzi, M. Peak
1985Photochemistry and Photobiology147 citations
Semantic Scholar
Differential expression of CYP1A, 2B, and 3A genes in the F344 rat following exposure to a polybrominated diphenyl ether mixture or individual components.
J. M. Sanders, L. Burka, C. S. Smith, W. Black +2 more
2005Toxicological Sciences143 citations Open access
Semantic Scholar
Methapyrilene Toxicity: Anchorage of Pathologic Observations to Gene Expression Alterations
H. Hamadeh, Brian Knight, A. Haugen, S. Sieber +9 more
2002Toxicologic pathology (Print)127 citations Open access
Semantic Scholar
Superoxide anion is generated from cellular metabolites by solar radiation and its components.
M. L. Cunningham, N. Krinsky, S. Giovanazzi, Meyrick J. Peak
1985Journal of Free Radicals in Biology & Medicine114 citations
Semantic Scholar
Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base.
M. Waters, G. Boorman, P. Bushel, M. L. Cunningham +10 more
2002107 citations Open access
Semantic Scholar
Expression of Base Excision DNA Repair Genes Is a Sensitive Biomarker for in Vivo Detection of Chemical-induced Chronic Oxidative Stress
I. Rusyn, S. Asakura, B. Pachkowski, B. Bradford +6 more
2004Cancer Research94 citations
Semantic Scholar
Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses.
R. Beyer, R. Fry, M. Lasarev, Lisa A. McConnachie +31 more
2007Toxicological Sciences83 citations
Semantic Scholar
Phenotypic anchoring of acetaminophen-induced oxidative stress with gene expression profiles in rat liver.
Christine L. Powell, O. Kosyk, Pamela K Ross, R. Schoonhoven +7 more
2006Toxicological Sciences80 citations Open access
Semantic Scholar
Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14,643.
M. Iida, C. H. Anna, Jennifer E Hartis, M. Bruno +11 more
2003Carcinogenesis75 citations
Semantic Scholar
Application of Toxicogenomics to Toxicology: Basic Concepts in the Analysis of Microarray Data
R. Irwin, G. Boorman, M. L. Cunningham, A. Heinloth +2 more
2004Toxicologic pathology (Print)68 citations Open access
Semantic Scholar
Unique patterns of gene expression changes in liver after treatment of mice for 2 weeks with different known carcinogens and non-carcinogens.
M. Iida, C. H. Anna, Wanda Holliday, J. Collins +3 more
2005Carcinogenesis59 citations
Semantic Scholar
Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype
E. Lobenhofer, J. O. Auman, P. Blackshear, G. Boorman +15 more
2008Genome Biology54 citations Open access
Semantic Scholar
Relationship of hepatocarcinogenicity and hepatocellular proliferation induced by mutagenic noncarcinogens vs carcinogens. II. 1- vs 2-nitropropane.
M. L. Cunningham, H. Matthews
1991Toxicology and Applied Pharmacology47 citations
Semantic Scholar
Workshop overview: use of genomic data in risk assessment.
M. L. Cunningham, M. Bogdanffy, T. Zacharewski, R. Hines
2003Toxicological Sciences43 citations Open access
Semantic Scholar
Further studies on the formation of oxygen radicals by potassium superoxide in aqueous medium for biochemical investigations.
B. Lokesh, M. L. Cunningham
1986Toxicology Letters40 citations Open access
Semantic Scholar
WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.
C. Woods, Amanda M. Burns, B. Bradford, Pamela K Ross +4 more
2007Toxicological Sciences39 citations
Semantic Scholar
A mouse is not a rat is not a human: species differences exist.
M. L. Cunningham
2002Toxicological Sciences37 citations
Semantic Scholar
Single-strand DNA breaks in rodent and human cells produced by superoxide anion or its reduction products.
M. L. Cunningham, J. G. Peak, Meyrick J. Peak
1987Mutation research37 citations
Semantic Scholar
Chemical effects in biological systems--data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and 'omics data.
J. Fostel, Danielle Choi, C. Zwickl, N. Morrison +25 more
2005Toxicological Sciences33 citations
Semantic Scholar
PPARs and Xenobiotic-Induced Adverse Effects: Relevance to Human Health
C. Lau, B. Abbott, J. Corton, M. L. Cunningham
2011PPAR Research30 citations Open access
Semantic Scholar
Determination of tamoxifen and metabolites in serum by capillary electrophoresis using a nonaqueous buffer system.
J. M. Sanders, L. Burka, M. Shelby, R. Newbold +1 more
1997Journal of Chromatography B: Biomedical Sciences and Applications29 citations
Semantic Scholar
Human consumption of methyleugenol and its elimination from serum.
A. Schecter, G. Lucier, M. L. Cunningham, K. Abdo +13 more
2004Environmental Health Perspectives28 citations Open access
Semantic Scholar
Time-course Comparison of Xenobiotic Activators of CAR and PPARα in Mouse Liver
Pamela K Ross, C. Woods, B. Bradford, O. Kosyk +3 more
2008Toxicology and Applied Pharmacology26 citations Open access
Semantic Scholar
Effect of peroxisome proliferators on the methylation and protein level of the c‐myc protooncogene in B6C3F1 mice liver
R. Ge, L. Tao, P. M. Kramer, M. L. Cunningham +1 more
2002Journal of biochemical and molecular toxicology24 citations
Semantic Scholar
Toward a checklist for exchange and interpretation of data from a toxicology study.
Jennifer M. Fostel, L. Burgoon, C. Zwickl, P. Lord +11 more
2007Toxicological Sciences21 citations
Semantic Scholar
Time course investigation of PPARalpha- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression.
C. Woods, O. Kosyk, B. Bradford, Pamela K Ross +5 more
2007Toxicology and Applied Pharmacology20 citations Open access
Semantic Scholar
Secretory phospholipase A₂-mediated progression of hepatotoxicity initiated by acetaminophen is exacerbated in the absence of hepatic COX-2.
V. Bhave, Shashikiran Donthamsetty, J. Latendresse, M. L. Cunningham +1 more
2011Toxicology and Applied Pharmacology19 citations
Semantic Scholar
A comparison of liver protein changes in mice and hamsters treated with the peroxisome proliferator Wy‐14,643
C. Giometti, S. Tollaksen, Xiaoli Liang, M. L. Cunningham
1998Electrophoresis17 citations
Semantic Scholar
Effects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism
M. L. Cunningham, B. Collins, M. Hejtmancik, R. Herbert +3 more
2010PPAR Research16 citations Open access
Semantic Scholar
Applying toxicogenomics in mechanistic and predictive toxicology.
M. L. Cunningham, L. Lehman-Mckeeman
2004Toxicological Sciences15 citations Open access
Semantic Scholar
Regulation of perfluorooctanoic acid–induced peroxisomal enzyme activities and hepatocellular growth by adrenal hormones
J. Thottassery, L. Winberg, J. Youssef, M. L. Cunningham +1 more
1992Hepatology15 citations
Semantic Scholar
Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase.
C. Woods, Amanda M. Burns, A. Maki, B. Bradford +6 more
2007Free Radical Biology & Medicine13 citations Open access
Semantic Scholar
Effects of DEHP in the Liver: Modes of Action and Species-Specific Differences
I. Rusyn, J. Peters, M. L. Cunningham
200912 citations
Semantic Scholar
Peroxisome proliferators do not activate the transcription factors AP-1, early growth response-1, or heat shock factors 1 and 2 in rats or hamsters.
M. O'Brien, M. L. Cunningham, B. Spear, H. Glauert
2002Toxicological Sciences11 citations
Semantic Scholar
Hepatic expression of polymerase beta, Ref-1, PCNA, and Bax in WY 14,643-exposed rats and hamsters.
Earle W. Holmes, C. Bingham, M. L. Cunningham
2002Experimental and molecular pathology (Print)11 citations
Semantic Scholar
Diminished energy metabolism and enhanced apoptosis in livers of B6C3F1 mice treated with the antihepatocarcinogen rotenone
C. Wang, J. Youssef, B. Saran, P. Rothberg +3 more
1999Molecular and Cellular Biochemistry11 citations
Semantic Scholar
Addendum: Standardizing global gene expression analysis between laboratories and across platforms
T. Bammler, R. Beyer, S. Bhattacharya, G. Boorman +60 more
2005Nature Methods10 citations Open access
Semantic Scholar
Cytotoxicity, genotoxicity and transforming activity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in rat tracheal epithelial cells.
Song-Yun Zhu, M. L. Cunningham, T. Gray, P. Nettesheim
1991Mutation research10 citations
Semantic Scholar
INHALATION TOXICITY STUDIES OF THE a,ß-UNSATURATED KETONES:2-Cyclohexene-1-One
M. L. Cunningham, H. Price, R. O'Connor, M. P. Moorman +3 more
20019 citations
Semantic Scholar
Toxicity studies of WY-14,643 (CAS No. 50892-23-4) administered in feed to male Sprague-Dawley rats, B6C3F1 mice, and Syrian hamsters.
M. L. Cunningham
2007Toxicity report series8 citations
Semantic Scholar
Inhalation toxicity studies of the alpha,beta-unsaturated ketones: ethyl vinyl ketone.
Daniel L. Morgan, S. M. Ward, R. E. Wilson, H. Price +3 more
2001Inhalation Toxicology8 citations
Semantic Scholar
Toxicologic responses to a complex coal conversion by-product: mammalian cell mutagenicity and dermal carcinogenicity
M. L. Cunningham, D. A. Haugen, F. Kirchner, C. Reilly
19857 citations
Semantic Scholar
Putting the fun into functional toxicogenomics.
M. L. Cunningham
2006Toxicological Sciences6 citations
Semantic Scholar
NTP Hepatotoxicity Studies of the Liver Carcinogen Methapyrilene Hydrochloride (CAS No. 135-23-9) Administered in Feed to Male F344/N Rats.
M. L. Cunningham
2000Toxicity report series6 citations
Semantic Scholar

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