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Xing-Shen Sun · SciRah

Researcher profile · Semantic Scholar

Xing-Shen Sun

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Xing-Shen Sun — researcher profile on SciRah

h-index: 25
Works: 57
Citations: 2,668

Most-cited papers

Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis.
Xing-Shen Sun, H. Sui, J. Fisher, Zi-Ying Yan +17 more
2010Journal of Clinical Investigation381 citations Open access
Semantic Scholar
Cloned ferrets produced by somatic cell nuclear transfer.
Zi-Yi Li, Xing-Shen Sun, Juan Chen, Xiao-Ming Liu +5 more
2006Developmental Biology191 citations Open access
Semantic Scholar
In Utero and Postnatal VX-770 administration rescues Multi-Organ Disease in a Ferret Model of Cystic Fibrosis
Xing-Shen Sun, Y. Yi, Zi-Ying Yan, B. H. Rosen +20 more
2019Science Translational Medicine179 citations Open access
Semantic Scholar
Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets.
Xing-Shen Sun, Zi-Ying Yan, Y. Yi, Zi-Yi Li +7 more
2008Journal of Clinical Investigation158 citations Open access
Semantic Scholar
Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size
Matthew B. Johnson, Xing-Shen Sun, Andrew Kodani, Rebeca Borges-Monroy +21 more
2018Nature148 citations Open access
Semantic Scholar
Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets.
A. Olivier, Y. Yi, Xing-Shen Sun, H. Sui +15 more
2012Journal of Clinical Investigation144 citations Open access
Semantic Scholar
The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease
Xin-Xia Peng, J. Alföldi, Kevin Gori, A. Eisfeld +34 more
2014Nature Biotechnology134 citations Open access
Semantic Scholar
Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets.
Xing-Shen Sun, A. Olivier, B. Liang, Y. Yi +23 more
2014American Journal of Respiratory Cell and Molecular Biology113 citations Open access
Semantic Scholar
Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR‐Knockout Ferrets
B. H. Rosen, I. Evans, S. Moll, Jaimie S. Gray +21 more
2018American Journal of Respiratory and Critical Care Medicine111 citations Open access
Semantic Scholar
Abnormal Glucose Tolerance in Infants and Young Children with Cystic Fibrosis.
Y. Yi, A. Norris, Kai Wang, Xing-Shen Sun +4 more
2016American Journal of Respiratory and Critical Care Medicine91 citations Open access
Semantic Scholar
Defective innate immunity and hyperinflammation in newborn cystic fibrosis transmembrane conductance regulator-knockout ferret lungs.
Nicholas W. Keiser, S. Birket, I. Evans, Scott R. Tyler +11 more
2015American Journal of Respiratory Cell and Molecular Biology90 citations Open access
Semantic Scholar
A Mutation in the Srrm4 Gene Causes Alternative Splicing Defects and Deafness in the Bronx Waltzer Mouse
Y. Nakano, Israt Jahan, Gregory Bonde, Xing-Shen Sun +6 more
2012PLoS Genetics88 citations Open access
Semantic Scholar
CFTR Influences Beta Cell Function and Insulin Secretion Through Non‐Cell Autonomous Exocrine‐Derived Factors
Xing-Shen Sun, Y. Yi, Wei-Liang Xie, B. Liang +9 more
2017Endocrinology80 citations Open access
Semantic Scholar
Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets.
Xing-Shen Sun, A. Olivier, Y. Yi, C. Pope +28 more
2014American Journal of Pathology74 citations Open access
Semantic Scholar
PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq
Scott R. Tyler, P. Rotti, Xing-Shen Sun, Y. Yi +7 more
2019Cell Reports69 citations Open access
Semantic Scholar
Optimization of Recombinant Adeno-Associated Virus-Mediated Expression for Large Transgenes, Using a Synthetic Promoter and Tandem Array Enhancers
Zi-Ying Yan, Xing-Shen Sun, Zehua Feng, Guiying Li +3 more
2015Human Gene Therapy60 citations Open access
Semantic Scholar
Transgenic ferret models define pulmonary ionocyte diversity and function
Feng Yuan, Grace N. Gasser, E. Lemire, D. Montoro +35 more
2023Nature56 citations Open access
Semantic Scholar
SURVIVAL IN A BAD NEIGHBORHOOD: PANCREATIC ISLETS IN CYSTIC FIBROSIS
A. Norris, K. Ode, L. Merjaneh, S. Sanda +4 more
2019Journal of Endocrinology46 citations Open access
Semantic Scholar
Highly Efficient Transgenesis in Ferrets Using CRISPR/Cas9-Mediated Homology-Independent Insertion at the ROSA26 Locus
Miao Yu, Xing-Shen Sun, Scott R. Tyler, B. Liang +11 more
2019Scientific Reports43 citations Open access
Semantic Scholar
A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling.
Y. Yi, Xing-Shen Sun, K. Gibson-Corley, Wei-Liang Xie +10 more
2016Endocrinology43 citations Open access
Semantic Scholar
Human Bocavirus Type-1 Capsid Facilitates the Transduction of Ferret Airways by Adeno-Associated Virus Genomes
Zi-Ying Yan, Zehua Feng, Xing-Shen Sun, Yu-Long Zhang +7 more
2017Human Gene Therapy39 citations Open access
Semantic Scholar
Efficient Term Development of Vitrified Ferret Embryos Using a Novel Pipette Chamber Technique
Xing-Shen Sun, Zi-Yi Li, Y. Yi, Juan Chen +2 more
2008Biology of Reproduction32 citations Open access
Semantic Scholar
Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets.
P. Rotti, Wei-Liang Xie, A. Poudel, Y. Yi +7 more
2018American Journal of Pathology30 citations Open access
Semantic Scholar
Bioelectric characterization of epithelia from neonatal CFTR knockout ferrets.
J. Fisher, Scott R. Tyler, Yu-Long Zhang, Ben J. Lee +13 more
2013American Journal of Respiratory Cell and Molecular Biology28 citations Open access
Semantic Scholar
Sox2 modulates Lef-1 expression during airway submucosal gland development.
Wei-Liang Xie, T. Lynch, Xiao-Ming Liu, Scott R. Tyler +13 more
2014American Journal of Physiology - Lung cellular and Molecular Physiology26 citations Open access
Semantic Scholar
Ferret models of alpha-1 antitrypsin deficiency develop lung and liver disease
N. He, Xiao-Ming Liu, Amber R. Vegter, T. I. A. Evans +20 more
2022JCI Insight23 citations Open access
Semantic Scholar
In utero and postnatal ivacaftor/lumacaftor therapy rescues multiorgan disease in CFTR-F508del ferrets
I. Evans, Xing-Shen Sun, B. Liang, Amber R. Vegter +22 more
2024JCI Insight21 citations Open access
Semantic Scholar
Repeat Dosing of AAV2.5T to Ferret Lungs Elicits an Antibody Response That Diminishes Transduction in an Age-Dependent Manner
Yinghua Tang, Zi-Ying Yan, Shen Lin, E. Huntemann +5 more
2020Molecular Therapy: Methods & Clinical Development19 citations Open access
Semantic Scholar
Recombinant Adeno-Associated Virus-Mediated Editing of the G551D Cystic Fibrosis Transmembrane Conductance Regulator Mutation in Ferret Airway Basal Cells
Zi-Ying Yan, K. Vorhies, Zehua Feng, S. Y. Park +5 more
2022Human Gene Therapy18 citations Open access
Semantic Scholar
Factors affecting the efficiency of embryo transfer in the domestic ferret (Mustela putorius furo).
Zi-Yi Li, Xing-Shen Sun, Juan Chen, G. H. Leno +1 more
2006Theriogenology16 citations Open access
Semantic Scholar
Defective Innate Immunity and Hyper-Inflammation in Newborn CFTR-Knockout Ferret Lungs.
Nicholas W. Keiser, S. Birket, I. Evans, Scott R. Tyler +9 more
201415 citations
Semantic Scholar
Oxidative stress and impaired insulin secretion in cystic fibrosis pig pancreas
Y. O'Malley, M. Coleman, Xing-Shen Sun, Junying Lei +10 more
2022Advances in Redox Research14 citations Open access
Semantic Scholar
Postentry Processing of Recombinant Adeno-Associated Virus Type 1 and Transduction of the Ferret Lung Are Altered by a Factor in Airway Secretions
Zi-Ying Yan, Xing-Shen Sun, I. Evans, Scott R. Tyler +4 more
2013Human Gene Therapy14 citations Open access
Semantic Scholar
Nuclear transfer of M-phase ferret fibroblasts synchronized with the microtubule inhibitor demecolcine.
Zi-Yi Li, Xin Chen, Xing-Shen Sun, Qi Zhou +3 more
2005Journal of Experimental Zoology Part A Comparative Experimental Biology13 citations
Semantic Scholar
Factors affecting the electrofusion of mouse and ferret oocytes with ferret somatic cells
Zi-Yi Li, Xing-Shen Sun, Juan Chen, Gregory H. Leno +1 more
2005Molecular Reproduction and Development10 citations
Semantic Scholar
The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models
A. Uc, B. Strandvik, Jianrong Yao, Xiao-Ming Liu +5 more
2022Clinical science9 citations Open access
Semantic Scholar
Ionocyte CFTR Coordinates Chloride Absorption and Secretion to Balance Airway Fluid.
Feng Yuan, Javahir Hajibabazade, Y. Yi, Adriane E Thompson +9 more
2025American Journal of Respiratory and Critical Care Medicine8 citations Open access
Semantic Scholar
CFTR represses a PDX1 axis to govern pancreatic ductal cell fate
P. Rotti, Y. Yi, Grace N. Gasser, Feng Yuan +16 more
2024iScience7 citations
Semantic Scholar
Incretin dysfunction and hyperglycemia in cystic fibrosis: role of acyl-ghrelin
Xing-Shen Sun, Y. Yi, B. Liang, Yu Yang +7 more
2019Journal of Cystic Fibrosis7 citations Open access
Semantic Scholar
Quantifying Insulin Sensitivity and Entero-Insular Responsiveness to Hyper- and Hypoglycemia in Ferrets
H. Sui, Y. Yi, Jianrong Yao, B. Liang +8 more
2014PLoS ONE6 citations Open access
Semantic Scholar
Novel Cystic Fibrosis Ferret Model Enables Visualization of CFTR Expression Cells and Genetic CFTR Reactivation
Feng Yuan, Xing-Shen Sun, Soo Yeun Park, Ying-Hua Tang +7 more
2025Human Gene Therapy4 citations Open access
Semantic Scholar
Nuclear transplantation by microinjection in rabbits
Qi Zhou, Zi-Yi Li, Zhong-Hua Liu, Xing-Shen Sun +2 more
19974 citations
Semantic Scholar
Genetic Engineering in the Ferret
Xing-Shen Sun, Zi-Ying Yan, Xiao-Ming Liu, A. Olivier +1 more
20143 citations
Semantic Scholar
Embryo cloning by nuclear transplantation in rabbits
Jing-He Tan, Qi Zhou, Zi-Yi Li, Xing-Shen Sun +2 more
19973 citations
Semantic Scholar
Research updates in cystic fibrosis related diabetes: Understanding pathophysiology, expanding animal and human islet models, and advancing clinical and translational research.
M. Putman, R. Hull-Meichle, Shafagh A. Waters, K. Tuggle +17 more
2026Journal of Cystic Fibrosis2 citations Open access
Semantic Scholar
ACUTE PANCREATITIS-INDUCED ISLET DYSFUNCTION IN FERRETS
Y. Yi, Xing-Shen Sun, B. Liang, N. He +4 more
2021Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]2 citations Open access
Semantic Scholar
Derivation of induced pluripotent stem cells from ferret somatic cells.
Jinghui Gao, S. Petraki, Xing-Shen Sun, Leonard A. Brooks +8 more
2020American Journal of Physiology - Lung cellular and Molecular Physiology2 citations Open access
Semantic Scholar
Generation of Alpha-1 Antitrypsin Knockout and PI*ZZ Ferrets Using Crispr/Cas9. A Genetic Model of Emphysema.
N. He, B. H. Rosen, Jaimie S. Gray, I. Evans +9 more
2018Annals of the American Thoracic Society2 citations Open access
Semantic Scholar
680. Optimization of rAAV-Mediated Expression for Large Transgenes Using a Synthetic Promoter and Tandem Array Enhancers
Zi-Ying Yan, Xing-Shen Sun, Zehua Feng, Guiying Li +3 more
20152 citations Open access
Semantic Scholar
Microinjection of mouse spermatozoa into rabbit oocytes
Zi-Yi Li, Qi Zhou, Xing-Hao Wen, Zhong-Hua Liu +3 more
19971 citations
Semantic Scholar

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