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F. Hakkim · SciRah

Researcher profile · Semantic Scholar

F. Hakkim

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F. Hakkim — researcher profile on SciRah

h-index: 18
Works: 57
Citations: 1,177

Most-cited papers

Chemical composition and antioxidant property of holy basil (Ocimum sanctum L.) leaves, stems, and inflorescence and their in vitro callus cultures.
F. Hakkim, C. G. Shankar, S. Girija
2007Journal of Agricultural and Food Chemistry190 citations
Semantic Scholar
Antioxidant property of selected Ocimum species and their secondary metabolite content
F. Hakkim, G. Arivazhagan, R. Boopathy
2013116 citations
Semantic Scholar
Comparative analysis of total phenolics, flavonoid content and antioxidant profile of different date varieties (Phoenix dactylifera L.) From Sultanate of Oman
Vandita Singh, N. Guizani, M. Essa, F. Hakkim +1 more
201294 citations
Semantic Scholar
Albumin Nano-Encapsulation of Piceatannol Enhances Its Anticancer Potential in Colon Cancer Via Downregulation of Nuclear p65 and HIF-1α
Alaa A. A. Aljabali, H. Bakshi, F. Hakkim, Yusuf A. Haggag +27 more
2020Cancers84 citations Open access
Semantic Scholar
Increased Markers of Oxidative Stress in Autistic Children of the Sultanate of Oman
M. Essa, G. Guillemin, M. Waly, M. Al-Sharbati +4 more
2011Biological Trace Element Research72 citations
Semantic Scholar
Effect of aqueous and ethanol extracts of Cassia auriculata L. flowers on diabetes using alloxan induced diabetic rats
F. Hakkim, S. Girija, R. Kumar, M. Jalaludeen
2007International Journal of Diabetes and Metabolism62 citations Open access
Semantic Scholar
Glycyrrhetinic acid: a promising scaffold for the discovery of anticancer agents
H. Hussain, Iftikhar Ali, Daijie Wang, F. Hakkim +7 more
2021Expert Opinion on Drug Discovery61 citations Open access
Semantic Scholar
Anti-cancer, anti-microbial and anti-oxidant properties of Acacia nilotica and their chemical profiling
S. Revathi, R. K. Govindarajan, N. Rameshkumar, F. Hakkim +3 more
201744 citations
Semantic Scholar
Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes
F. Hakkim, H. Bakshi, S. Khan, M. Nasef +8 more
2019OncoTarget40 citations Open access
Semantic Scholar
Molecular Mechanism of Crocin Induced Caspase Mediated MCF-7 Cell Death: In Vivo Toxicity Profiling and Ex Vivo Macrophage Activation.
H. Bakshi, F. Hakkim, S. Sam
2016Asian Pacific Journal of Cancer Prevention38 citations Open access
Semantic Scholar
Boswellia Gum Resin and Essential Oils: Potential Health Benefits − An Evidence Based Review
L. Rashan, F. Hakkim, Mohammed Idrees, M. Essa +7 more
2019International journal of Nutrition Pharmacology Neurological Diseases37 citations
Semantic Scholar
Induction of HT-29 Colon Cancer Cells Apoptosis by Pyrogallol with Growth Inhibiting Efficacy Against Drug-Resistant Helicobacter pylori.
S. Revathi, F. Hakkim, N. R. Kumar, H. Bakshi +6 more
2019Anti-Cancer Agents in Medicinal Chemistry28 citations Open access
Semantic Scholar
Boswellic acids: privileged structures to develop lead compounds for anticancer drug discovery
H. Hussain, Iftikhar Ali, Daijie Wang, F. Hakkim +4 more
2021Expert Opinion on Drug Discovery26 citations Open access
Semantic Scholar
Exploiting the Metabolism of the Gut Microbiome as a Vehicle for Targeted Drug Delivery to the Colon
H. Bakshi, G. Quinn, Alaa A. A. Aljabali, F. Hakkim +7 more
2021Pharmaceuticals24 citations Open access
Semantic Scholar
Dietary crocin reverses melanoma metastasis
H. Bakshi, F. Hakkim, S. Sam, F. Javid +1 more
2018Journal of Biomedical Research24 citations Open access
Semantic Scholar
Frankincense diterpenes as a bio-source for drug discovery
H. Hussain, L. Rashan, Uzma Hassan, M. Abbas +2 more
2022Expert Opinion on Drug Discovery22 citations Open access
Semantic Scholar
In Vivo Anti Cancer Potential of Pyrogallol in Murine Model of Colon Cancer
S. Revathi, F. Hakkim, N. R. Kumar, H. Bakshi +6 more
2019Asian Pacific Journal of Cancer Prevention21 citations Open access
Semantic Scholar
Nucleic acid aptamers as potential Nucleus targeted drug delivery system.
G. Shrivastava, H. Bakshi, Alaa A. A. Aljabali, Vijay Mishra +6 more
2020Current Drug Delivery19 citations Open access
Semantic Scholar
Recent Advances in Extraction, Characterization, and Potential Use of Citral
M. Idrees, F. Hakkim, Gowhar A. Naikoo, Israr Ul Hassan
2019Natural Bio-active Compounds17 citations
Semantic Scholar
An in vitro evidence for caffeic acid, rosmarinic acid and trans cinnamic acid as a skin protectant against γ-radiation
F. Hakkim, Miwa Miura, N. Matsuda, Ahmed Suleiman Alharassi +4 more
201417 citations
Semantic Scholar
Frankincense derived heavy terpene cocktail boosting breast cancer cell (MDA-MB-231) death in vitro
F. Hakkim, Mohammed Al-Buloshi, J. Al-Sabahi
201516 citations Open access
Semantic Scholar
Anti-poliovirus activity of Nerium oleander aqueous extract
G. Sanna, S. Madeddu, Alessandra Serra, D. Collu +3 more
2019Natural Product Research13 citations
Semantic Scholar
Chemical composition and anti-proliferative effect of Oman's Ganoderma applanatum on breast cancer and cervical cancer cells
F. Hakkim, Mohammed Al-Buloshi, Jackson Achankunju
201613 citations Open access
Semantic Scholar
Reduced levels of antioxidant proteins in children with autism in Oman
Essa Mm, G. Guillemin, M. Waly, M. Al-Sharbati +4 more
201213 citations
Semantic Scholar
Mechanochemical syntheses, crystal structures, and photo-luminescent properties of a new hydrazone and its nickel and cadmium complexes
S. Sathiyakumar, P. Selvam, F. Hakkim, K. Srinivasan +1 more
2018Journal of coordination chemistry12 citations Open access
Semantic Scholar
Potential of Aucklandia Lappa Decne Ethanolic Extract to Trigger Apoptosis of Human T47D and Hela Cells
S. Hasson, A. S. Al-Shubi, J. Z. Al-Busaidi, M. Al-Balushi +4 more
2018Asian Pacific Journal of Cancer Prevention10 citations
Semantic Scholar
Role of Dietary Crocin in In Vivo Melanoma Tumor Remission
H. Bakshi, F. Hakkim, S. Sam, F. Javid
2017Asian Pacific Journal of Cancer Prevention10 citations
Semantic Scholar
Assessment of in vitro cytotoxicity of saffron (Crocus sativus L.) on cervical cancer cells (HEp-2) and their in vivo pre-clinical toxicity in normal swiss albino mice
H. Bakshi, F. Hakkim, S. Sam, Mohammed Al-Buloshi
201610 citations
Semantic Scholar
Antioxidant property of leaves and calluses extracts of in-vitro grown 5 different Ocimum species
Hyuk Song, Prem Kumar, G. Arivazhagan, Sang-Ill Lee +5 more
201210 citations Open access
Semantic Scholar
The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis
Charles A. Day, F. Grigore, F. Hakkim, Souren Paul +10 more
2024Current Biology5 citations Open access
Semantic Scholar
Correction: Aljabali, A.A.A.; et al. Albumin Nano-Encapsulation of Piceatannol Enhances Its Anticancer Potential in Colon Cancer via down Regulation of Nuclear p65 and HIF-1α. Cancers 2020, 12, 113
Alaa A. A. Aljabali, H. Bakshi, F. Hakkim, Yusuf A. Haggag +27 more
2020Cancers5 citations Open access
Semantic Scholar
Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes
F. Hakkim, H. Bakshi, S. Khan, M. Nasef +8 more
2020OncoTarget5 citations Open access
Semantic Scholar
Intrinsic Evaluation of Antiurolithiatic Capacity of Argemone mexicana L. in Wistar Albino Rats
Chilivery Ravi Kiran, C. Rajkuberan, A. Sangilimuthu, F. Hakkim +2 more
20214 citations
Semantic Scholar
A REVIEW ON PHYTO PHARMACOLOGICAL ASPECTS OF PELTOPHORUM PTEROCARPUM (DC) BAKER EX. K HEYNE.
M. Babu, A. Anand, F. Hakkim, Q. Haq
20164 citations Open access
Semantic Scholar
Chemical Profiling and Anti-Microbial Activity of Frankincense (Boswellia sacra) Derived Heavy oil
F. Hakkim, S. Hassan, J. Al-Sabahi, Mohammed Al-Buloshi
20164 citations
Semantic Scholar
H3F3A K27M mutations drive a repressive transcriptome by modulating chromatin accessibility independent of H3K27me3 in Diffuse Midline Glioma
S. Bhattarai, F. Hakkim, Charles A. Day, F. Grigore +4 more
2025Epigenetics & Chromatin3 citations Open access
Semantic Scholar
Immunomodulatory Potential of Combining Some Traditional Medicinal Plants In Vivo
S. Hasson, Albantova Aa, Idris Ma, J. Al-Busaidi +5 more
20193 citations
Semantic Scholar
H3F3A K27M Mutations Drives a Repressive Transcriptome by Modulating Chromatin Accessibility, Independent of H3K27me3 in Diffuse Midline Glioma
S. Bhattarai, F. Hakkim, Charles A. Day, F. Grigore +4 more
2024bioRxiv1 citations Open access
Semantic Scholar
The histone H3.3 K27M mutation found in diffuse midline gliomas coordinately disrupts adjacent H3.3 Ser31 phosphorylation and the fidelity of chromosome segregation
Charles A. Day, F. Grigore, F. Hakkim, Alyssa Langfald +8 more
2022bioRxiv1 citations Open access
Semantic Scholar
Enhancement of Rosmarinic Acid Content by Biotechnological Approaches and Metabolic Engineering
F. Hakkim, M. Idrees, H. Bakshi, Laiqahmed Mombasawala +1 more
2019Natural Bio-active Compounds1 citations
Semantic Scholar
Gc-ms chemical profiling of heavy oil derived from commercial variety oman s frankincense and their anti microbial activity
F. Hakkim, S. Hassan, Jamal Al-Sabah
20161 citations
Semantic Scholar
IN VITRO DPPH RADICAL SCAVENGING AND ANTI-BACTERIAL ACTIVITY OF OMAN'S CYMBOPOGON Short Communication
F. Hakkim, Jackson Achankunju, S. S. Hasan
20161 citations
Semantic Scholar
CONSERVATION OF OMANI FRANKINCENSE (BOSWELLIA SACRA, BURSERACEAE) THROUGH PLANT TISSUE CULTURE APPROACH
Q. Mohammed, I. Haq, Wafa Thabit Al-Riyami, Samyah Khamis Al-Jadeedi +5 more
20141 citations
Semantic Scholar
Biomarker-driven and gene-enhanced viral therapy for malignant peripheral nerve sheath tumor
Meghna Saxena, Love Li, Brady G. Strittmatter, Kyle B. Williams +14 more
2026bioRxiv0 citations Open access
Semantic Scholar
EPCO-13. EZHIP SELECTIVELY REPRESSES GENOME STABILITY PROGRAMS IN NEURAL STEM CELLS TO PROMOTE EPIGENETIC VULNERABILITY AND TRANSFORMATION
S. Bhattarai, Josephine Mapunda, F. Hakkim, Charles A. Day +4 more
2025Neuro-Oncology0 citations
Semantic Scholar
DMG-46. Epigenomic Reprogramming by EZHIP Drives Tumorigenesis and Stem-like States in Diffuse Midline Gliomas.
S. Bhattarai, F. Hakkim, F. Grigore, Charles A. Day +3 more
2025Neuro-Oncology Pediatrics0 citations Open access
Semantic Scholar
TMOD-10. Mouse Models of H3.3K27M, G34R, and EZHIP Define Distinct Epigenetic Routes to Gliomagenesis
F. Grigore, Charles A. Day, S. Bhattarai, F. Hakkim +3 more
2025Neuro-Oncology0 citations
Semantic Scholar
Abstract B033: Histone H3.3 K27M and G34R/V glioma driver mutations inhibit mitotic phosphorylation of H3.3 S31, driving tumor formation by inducing chromosomal instability
Charles A. Day, F. Grigore, Alyssa Langfald, F. Hakkim +4 more
2024Cancer Research0 citations
Semantic Scholar
EPCO-04. H3F3A K27M MUTATION DRIVES A REPRESSIVE TRANSCRIPTOME VIA REDUCED SERINE 31 PHOSPHORYLATION BY MODULATING CHROMATIN ACCESSIBILITY, INDEPENDENT OF H3K27ME3 IN DIFFUSE MIDLINE GLIOMA
S. Bhattarai, Charles A. Day, F. Hakkim, F. Grigore +3 more
2024Neuro-Oncology0 citations Open access
Semantic Scholar
Abstract 1736: Elucidating the oncogenic mechanisms in diffuse midline glioma: Comparative analysis of h3k27m mutation and k27 methylation loss on gene expression profiles via RNA sequencing
S. Bhattarai, F. Hakkim, Charles A. Day, F. Grigore +3 more
2024Cancer Research0 citations
Semantic Scholar

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