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A. Tunek · SciRah

Researcher profile · Semantic Scholar

A. Tunek

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A. Tunek — researcher profile on SciRah

h-index: 13
Works: 16
Citations: 833

Most-cited papers

Reversible fatty acid conjugation of budesonide. Novel mechanism for prolonged retention of topically applied steroid in airway tissue.
A. Miller‐Larsson, H. Mattsson, E. Hjertberg, M. Dahlbäck +2 more
1998Drug Metabolism And Disposition161 citations
Semantic Scholar
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
Hong Wan, Mikael Rehngren, F. Giordanetto, Fredrik Bergström +1 more
2007Journal of Medicinal Chemistry142 citations
Semantic Scholar
Bambuterol, a carbamate ester prodrug of terbutaline, as inhibitor of cholinesterases in human blood.
A. Tunek, L. Svensson
1988Drug Metabolism And Disposition96 citations
Semantic Scholar
Mechanism of benzene toxicity. Effects of benzene and benzene metabolites on bone marrow cellularity, number of granulopoietic stem cells and frequency of micronuclei in mice.
A. Tunek, B. Högstedt, T. Olofsson
1982Chemico-Biological Interactions71 citations
Semantic Scholar
Toxic effects of benzene and benzene metabolites on granulopoietic stem cells and bone marrow cellularity in mice.
A. Tunek, T. Olofsson, M. Berlin
1981Toxicology and Applied Pharmacology69 citations
Semantic Scholar
Plasma homocysteine and thiol compound fractions after oral administration of N-acetylcysteine.
B. Hultberg, A. Andersson, P. Masson, M. Larson +1 more
1994Scandinavian Journal of Clinical and Laboratory Investigation63 citations
Semantic Scholar
The right compound in the right assay at the right time: an integrated discovery DMPK strategy
P. Ballard, P. Brassil, K. Bui, H. Dolgos +3 more
2012Drug metabolism reviews (Softcover ed.)52 citations
Semantic Scholar
Pharmacologic importance of the reversible fatty acid conjugation of budesonide studied in a rat cell line In vitro.
E. Wieslander, E. Delander, L. Järkelid, E. Hjertberg +2 more
1998American Journal of Respiratory Cell and Molecular Biology48 citations
Semantic Scholar
N-isobutyrylcysteine, a donor of systemic thiols, does not reduce the exacerbation rate in chronic bronchitis.
A. ekberg-Jansson, M. Larson, William Macnee, A. Tunek +3 more
1999European Respiratory Journal37 citations Open access
Semantic Scholar
Glutathione in bronchoalveolar lavage fluid from smokers is related to humoral markers of inflammatory cell activity
M. Linden, L. Håkansson, K. Ohlsson, Karin Sjödin +3 more
1989Inflammation32 citations
Semantic Scholar
Discovery of phosphoinositide 3-kinases (PI3K) p110β isoform inhibitor 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2-methylmorpholin-4-yl]-1H-pyrimidin-2-one, an effective antithrombotic agent without associated bleeding and insulin resistance.
F. Giordanetto, Andreas Wallberg, S. Ghosal, T. Iliefski +7 more
2012Bioorganic & Medicinal Chemistry Letters19 citations Open access
Semantic Scholar
Chapter 10 – Metabolism and pharmacokinetic optimization strategies in drug discovery
P. Ballard, P. Brassil, K. Bui, H. Dolgos +3 more
201313 citations
Semantic Scholar
Toxic effects on mouse bone marrow caused by inhalation of benzene
Kristina Toft, T. Olofsson, A. Tunek, M. Berlin
1982Archives of Toxicology13 citations
Semantic Scholar
Bambuterol: Uptake and Metabolism in Guinea Pig Isolated Lungs
Å. Ryrfeldt, E. Nilsson, A. Tunek, Leif Svensson
1988Pharmaceutical Research9 citations
Semantic Scholar
The discovery of a selective and potent A2a agonist with extended lung retention
A. Åstrand, E. Lamm Bergström, Hui Zhang, Lena Börjesson +9 more
2015Pharmacology Research & Perspectives8 citations Open access
Semantic Scholar
A NEW METHOD FOR STUDYING THE COVALENT BINDING OF POLYCYCLIC AROMATIC HYDROCARBONS TO PROTEINS
H. Wallin, Cecilia Schelin, A. Tunek, B. Jergil
19810 citations
Semantic Scholar

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