Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

J. Leatherman · SciRah

Researcher profile · Semantic Scholar

J. Leatherman

Share profile

J. Leatherman — researcher profile on SciRah

h-index: 20
Works: 70
Citations: 2,445

Most-cited papers

Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial
E. Abraham, R. Wunderink, H. Silverman, T. Perl +113 more
1995685 citations
Semantic Scholar
Neoadjuvant cabozantinib and nivolumab convert locally advanced hepatocellular carcinoma into resectable disease with enhanced antitumor immunity
W. Ho, Qing-Feng Zhu, J. Durham, A. Popovic +27 more
2021Nature Cancer265 citations Open access
Semantic Scholar
Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation.
L. Emens, Justin M. Asquith, J. Leatherman, B. Kobrin +13 more
2009Journal of Clinical Oncology238 citations Open access
Semantic Scholar
A Vascular Endothelial Growth Factor Receptor-2 Inhibitor Enhances Antitumor Immunity through an Immune-Based Mechanism
Elizabeth A. Manning, John Ullman, J. Leatherman, Justin M. Asquith +5 more
2007Clinical Cancer Research203 citations
Semantic Scholar
A STING agonist given with OX40 receptor and PD-L1 modulators primes immunity and reduces tumor growth in tolerized mice
J. Foote, M. Kok, J. Leatherman, T. Armstrong +6 more
2017Cancer immunology research131 citations Open access
Semantic Scholar
Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma
Daniel H. Shu, W. Ho, L. T. Kagohara, Alexander A. Girgis +35 more
2024Nature Immunology125 citations
Semantic Scholar
Na, K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis
S. Rajasekaran, T. P. Huynh, Daniel Wolle, Cromwell E. Espineda +10 more
2010Molecular Cancer Therapeutics84 citations Open access
Semantic Scholar
A Feasibility Study of Cyclophosphamide, Trastuzumab, and an Allogeneic GM-CSF-secreting Breast Tumor Vaccine for HER-2+ Metastatic Breast Cancer
Gang Chen, Richa Gupta, Silvia Petrik, M. Laiko +17 more
2014Cancer immunology research79 citations Open access
Semantic Scholar
Viral status, immune microenvironment and immunological response to checkpoint inhibitors in hepatocellular carcinoma
W. Ho, L. Danilova, S. Lim, Rohan Verma +7 more
2020Journal for ImmunoTherapy of Cancer60 citations Open access
Semantic Scholar
Profiling of syngeneic mouse HCC tumor models as a framework to understand anti–PD-1 sensitive tumor microenvironments
D. Zabransky, L. Danilova, J. Leatherman, T. Lopez-Vidal +16 more
2022Hepatology54 citations Open access
Semantic Scholar
Effects of B cell-activating factor on tumor immunity.
M. Yarchoan, W. Ho, Aditya A. Mohan, Yajas Shah +9 more
2020JCI Insight51 citations Open access
Semantic Scholar
Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial
E. T. Torres, W. Ho, Ludmila Danilova, Joseph A. Tandurella +23 more
2024Nature Cancer50 citations
Semantic Scholar
Systemic inhibition of PTPN22 augments anticancer immunity.
W. Ho, S. Croessmann, Jianping Lin, Z. Phyo +19 more
2021Journal of Clinical Investigation49 citations Open access
Semantic Scholar
Ras mutation impairs epithelial barrier function to a wide range of nonelectrolytes.
J. M. Mullin, J. Leatherman, M. Valenzano, Erika Patricia Rendón Huerta +6 more
2005Molecular Biology of the Cell44 citations Open access
Semantic Scholar
CD4 T cell–activating neoantigens enhance personalized cancer vaccine efficacy
Amanda L. Huff, Gabriella Longway, Jacob T. Mitchell, Lalitya Andaloori +16 more
2023JCI Insight35 citations Open access
Semantic Scholar
Age-related divergence of circulating immune responses in patients with solid tumors treated with immune checkpoint inhibitors
C. Kao, S. Charmsaz, Hua-Ling Tsai, K. Aziz +26 more
2025Nature Communications34 citations Open access
Semantic Scholar
Sorafenib combined with HER-2 targeted vaccination can promote effective T cell immunity in vivo
M. Sunay, J. Foote, J. Leatherman, J. Edwards +4 more
2017International Immunopharmacology34 citations Open access
Semantic Scholar
A phase 2 trial of CXCR4 antagonism and PD1 inhibition in metastatic pancreatic adenocarcinoma reveals recruitment of T cells but also immunosuppressive macrophages
K. Bever, Sarah M. Shin, J. Durham, Hanfei Qi +20 more
2025Oncoimmunology28 citations Open access
Semantic Scholar
Fibroblasts in the aged pancreas drive pancreatic cancer progression
D. Zabransky, Yash Chhabra, Mitchell E. Fane, Emma Kartalia +15 more
2024Cancer Research28 citations
Semantic Scholar
Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade
Daniel H. Shu, W. Ho, L. T. Kagohara, Alexander A. Girgis +30 more
2023bioRxiv20 citations Open access
Semantic Scholar
Context-Dependent Immunomodulatory Effects of MEK Inhibition are Enhanced with T-cell Agonist Therapy
L. Dennison, Amanda N. Ruggieri, Aditya A. Mohan, J. Leatherman +6 more
2021Cancer immunology research20 citations Open access
Semantic Scholar
Implantation of a neoantigen-targeted hydrogel vaccine prevents recurrence of pancreatic adenocarcinoma after incomplete resection
D. Delitto, D. Zabransky, Fangluo Chen, Elizabeth D. Thompson +20 more
2021Oncoimmunology18 citations Open access
Semantic Scholar
Feasibility and efficacy of neoadjuvant cabozantinib and nivolumab in patients with borderline resectable or locally advanced hepatocellular carcinoma (HCC).
M. Yarchoan, Qing-Feng Zhu, J. Durham, N. Gross +15 more
2021Journal of Clinical Oncology18 citations
Semantic Scholar
Tumor-derived CCL2 drives tumor growth and immunosuppression in IDH1-mutant cholangiocarcinoma
D. Zabransky, Emma Kartalia, Jae W. Lee, J. Leatherman +14 more
2024Hepatology16 citations
Semantic Scholar
A feasibility study of combination therapy with trastuzumab (T), cyclophosphamide (CY), and an allogeneic GM-CSF-secreting breast tumor vaccine for the treatment of HER2+ metastatic breast cancer.
L. Emens, Richa Gupta, Silvia Petrik, Marina Laiko +13 more
2011Journal of Clinical Oncology16 citations
Semantic Scholar
Integrated T cell cytometry metrics for immune-monitoring applications in immunotherapy clinical trials
Dimitri N. Sidiropoulos, G. Stein-O'Brien, L. Danilova, Nicole E. Gross +8 more
2022JCI Insight14 citations Open access
Semantic Scholar
A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence
T. Heumann, M. Baretti, E. Sugar, J. Durham +11 more
2022Clinical Epigenetics10 citations Open access
Semantic Scholar
Anti-CTLA4 therapy leads to early expansion of a peripheral Th17 population and induction of Th1 cytokines
Mari Nakazawa, S. Charmsaz, E. Hallab, Mike Fang +20 more
2025Cancer immunology research6 citations Open access
Semantic Scholar
A new Neu—a syngeneic model of spontaneously metastatic HER2-positive breast cancer
A. Baugh, E. Gonzalez, V. Narumi, J. Kreger +13 more
2024Clinical and Experimental Metastasis6 citations Open access
Semantic Scholar
A clinical study of tremelimumab alone or in combination with olaparib in patients with advanced epithelial ovarian cancer.
S. Gaillard, Maureen Berg, J. Harrison, Peng Huang +10 more
2020Journal of Clinical Oncology6 citations
Semantic Scholar
Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy
Howard L. Li, S. Charmsaz, Mari Nakazawa, Stephanie L Alden +26 more
2025Cancer Research Communications5 citations
Semantic Scholar
Abstract 4749: Cyclophosphamide induces dose dependent apoptosis of CD4+FoxP3+ regulatory T cells relative to CD4+FoxP3- effector T cells in breast cancer patients.
Gang Chen, J. Leatherman, M. Sunay, L. Emens
20134 citations
Semantic Scholar
DNAJ-PKAc induces metabolic rewiring and enhanced glutamine flux in fibrolamellar HCC
Zeal Kamdar, Ethan Neumann, Kathryn Howe, Donald Long +23 more
2025Journal of Hepatology3 citations
Semantic Scholar
Abstract 2222: Trimethylamine-N-oxide (TMAO) mediates immunotherapy resistance in advanced HCC
Mari Nakazawa, Vivian L. Raj, N. Rajeshkumar, N. Rastkari +11 more
2025Cancer Research3 citations
Semantic Scholar
964MO Entinostat, nivolumab and ipilimumab in advanced HER2-negative breast cancer (ETCTN-9844)
E. R. Roussos Torres, J. Leatherman, C. Rafie, A. Brufsky +16 more
2021Annals of Oncology3 citations Open access
Semantic Scholar
Increasing doses of cyclophosphamide suppress antigen-specific T helper-dependent immunity induced by a GM-CSF-secreting breast tumor vaccine
L. Emens, Justin M. Asquith, J. Leatherman, M. Daphtary +6 more
20083 citations
Semantic Scholar
Cancer-Associated Fibroblasts Promote Epithelial-Mesenchymal Transition and Classical to Basal Subtype Shift in Pancreatic Cancer
Kylie Belanger, Samantha Guinn, Brayan Perez, Yeonju Cho +35 more
2026Cancer Research2 citations Open access
Semantic Scholar
Time-of-day of first checkpoint inhibitor dose influences clinical outcomes and immune responses in hepatocellular carcinoma
Howard L. Li, S. Charmsaz, B. Reisman, Franshisca Hayek +25 more
2026Journal for ImmunoTherapy of Cancer2 citations
Semantic Scholar
Abstract 3985: Sorafenib modulates macrophages to promote T helper type 1 immunity.
M. Sunay, J. Leatherman, Gang Chen, L. Emens
20132 citations
Semantic Scholar
Cytometric Atlas of Combination Immunotherapy in Pancreatic Cancer: Blood-Based Signatures Reveal Vaccine and Checkpoint Inhibitor Responses
Dimitri N. Sidiropoulos, Zhehao Zhang, J. Durham, S. Charmsaz +19 more
2026Cancer immunology research1 citations
Semantic Scholar
A Clinical Study of Tremelimumab, Alone or in Combination with Olaparib, for Recurrent Epithelial Ovarian Cancer
Stéphanie Gaillard, Neha Verma, Maureen Berg, J. Harrison +12 more
2025Gynecologic Oncology1 citations Open access
Semantic Scholar
Abstract B034: Antigen-presenting cancer-associated fibroblasts are found in immunotherapy-sensitive murine models of pancreatic ductal adenocarcinoma
Saumya Y. Maru, Kathryn Howe, Lalitya Andaloori, J. Leatherman +3 more
2024Cancer Research1 citations
Semantic Scholar
Abstract 1682: Imaging mass cytometry reveals key spatial features among immune cells in hepatocellular carcinomas treated with neoadjuvant cabozantinib and nivolumab
Shu Zhang, Qing-Feng Zhu, Nicole Groß, S. Charmsaz +15 more
2021Immunology1 citations
Semantic Scholar
1470P Oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence
T. R. Heumann, M. Baretti, E. Sugar, J. Durhman +11 more
2021Annals of Oncology1 citations Open access
Semantic Scholar
AVascular Endothelial Growth Factor Receptor-2 Inhibitor Enhances Antitumor Immunity through an Immune-BasedMechanism
Elizabeth A. Manning, John Ullman, J. Leatherman, Justin M. Asquith +5 more
20071 citations
Semantic Scholar
Interrogating acquired PD-1 resistance through BET bromodomain inhibition in hepatocellular carcinoma murine models.
C. Pazzi, S. Haldar, T. Lopez-Vidal, A. Skaist +10 more
2026Journal of Clinical Oncology0 citations
Semantic Scholar
Peripheral Th17 immune signature associates with excellent response to anti-PD1/anti-PD-L1 therapy across solid tumors.
Howard L. Li, S. Charmsaz, C. Kao, C. Pazzi +23 more
2026Cancer immunology research0 citations
Semantic Scholar
Abstract PR010: A mutant KRAS-targeted peptide vaccine in combination with RAS(ON) multi-selective inhibition and immune checkpoint modulators enhances anti-tumor immunity in preclinical PDAC models
Zi-Rui Zhu, Benjamin C. Barrett, Aadi Bhattacharya, H. Wang +12 more
2026Cancer Research0 citations
Semantic Scholar
Abstract 6036: Antigen-presenting cancer-associated fibroblasts in murine pancreatic tumors differentially control regulatory T cell phenotype and function via CCL22
Saumya Y. Maru, Meredith Wetzel, Jacob T. Mitchell, Nicole E. Gross +10 more
2026Cancer Research0 citations
Semantic Scholar
Abstract 6541: Time-of-day of first checkpoint inhibitor dose influences clinical outcomes and immune responses in hepatocellular carcinoma
Howard L. Li, S. Charmsaz, B. Reisman, Franshisca Hayek +25 more
2026Cancer Research0 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

M. Yarchoan×23
Invite
M. Yarchoan — researcher profile on SciRah
S. Charmsaz×18
Invite
S. Charmsaz — researcher profile on SciRah
E. Jaffee×18
Invite
E. Jaffee — researcher profile on SciRah
E. Fertig×14
Invite
E. Fertig — researcher profile on SciRah

×13

Invite

D. Zabransky — researcher profile on SciRah

Invite

L. Emens — researcher profile on SciRah

Invite

M. Baretti — researcher profile on SciRah

Invite

J. Durham — researcher profile on SciRah

Nicole E. Gross×11

Invite

Nicole E. Gross — researcher profile on SciRah

Invite

W. Ho — researcher profile on SciRah

T. Armstrong×10

Invite

T. Armstrong — researcher profile on SciRah

Alexei G. Hernandez×10

Invite

Alexei G. Hernandez — researcher profile on SciRah