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K. Botting · SciRah

Researcher profile · Semantic Scholar

K. Botting

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K. Botting — researcher profile on SciRah

h-index: 21
Works: 59
Citations: 1,526

Most-cited papers

Placental Adaptations in Growth Restriction
Song Zhang, T. Regnault, P. Barker, K. Botting +4 more
2015Nutrients221 citations Open access
Semantic Scholar
Improving pregnancy outcomes in humans through studies in sheep.
J. Morrison, M. Berry, K. Botting, J. Darby +16 more
2018American Journal of Physiology. Regulatory Integrative and Comparative Physiology164 citations Open access
Semantic Scholar
Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic
J. Morrison, K. Botting, J. Darby, A. David +15 more
2018Journal of Physiology135 citations Open access
Semantic Scholar
Early origins of heart disease: Low birth weight and determinants of cardiomyocyte endowment
K. Botting, Kimberley C. W. Wang, M. Padhee, I. Mcmillen +6 more
2012Clinical and Experimental Pharmacology and Physiology92 citations Open access
Semantic Scholar
Maternal undernutrition reduces P-glycoprotein in guinea pig placenta and developing brain in late gestation.
Poh S. Soo, J. Hiscock, K. Botting, C. Roberts +2 more
2012Reproductive Toxicology88 citations
Semantic Scholar
Near to One's Heart: The Intimate Relationship Between the Placenta and Fetal Heart
E. Camm, K. Botting, A. Sferruzzi-Perri
2018Frontiers in Physiology78 citations Open access
Semantic Scholar
Intervention against hypertension in the next generation programmed by developmental hypoxia
K. Brain, B. Allison, Y. Niu, C. Cross +6 more
2019PLoS Biology65 citations Open access
Semantic Scholar
Translatable mitochondria-targeted protection against programmed cardiovascular dysfunction
K. Botting, K. Skeffington, Y. Niu, B. J. Allison +7 more
2020Science Advances61 citations Open access
Semantic Scholar
Melatonin modulates the fetal cardiovascular defense response to acute hypoxia
A. Thakor, B. Allison, Y. Niu, K. Botting +3 more
2015Journal of Pineal Research48 citations Open access
Semantic Scholar
Chronic hypoxia in ovine pregnancy recapitulates physiological and molecular markers of preeclampsia in the mother, placenta and offspring
W. Tong, B. Allison, K. Brain, O. Patey +13 more
2022HYPERTENSION44 citations Open access
Semantic Scholar
Early restriction of placental growth results in placental structural and gene expression changes in late gestation independent of fetal hypoxemia
Song Zhang, P. Barker, K. Botting, C. Roberts +3 more
2016Physiological Reports43 citations Open access
Semantic Scholar
The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults
M. Lock, R. Tellam, K. Botting, Kimberley C. W. Wang +4 more
2018Journal of Physiology41 citations Open access
Semantic Scholar
Altered autonomic control of heart rate variability in the chronically hypoxic fetus
C. Shaw, B. Allison, N. Itani, K. Botting +3 more
2018Journal of Physiology39 citations Open access
Semantic Scholar
The Periconceptional Environment and Cardiovascular Disease: Does In Vitro Embryo Culture and Transfer Influence Cardiovascular Development and Health?
M. Padhee, Song Zhang, Shervi Lie, Kimberley C. W. Wang +4 more
2015Nutrients39 citations Open access
Semantic Scholar
Noninvasive high-intensity focused ultrasound treatment of twin-twin transfusion syndrome: A preliminary in vivo study
C. Shaw, J. Civale, K. Botting, Y. Niu +4 more
2016Science Translational Medicine38 citations Open access
Semantic Scholar
Second-harmonic generation and two-photon-excited autofluorescence microscopy of cardiomyocytes: quantification of cell volume and myosin filaments.
Samuel J Wallace, J. Morrison, K. Botting, Tak W. Kee
2008Journal of Biomedical Optics34 citations Open access
Semantic Scholar
IGF-2R-Mediated Signaling Results in Hypertrophy of Cultured Cardiomyocytes from Fetal Sheep1
Kimberley C. W. Wang, D. Brooks, K. Botting, J. Morrison
2012Biology of Reproduction31 citations Open access
Semantic Scholar
Adverse Intrauterine Environment and Cardiac miRNA Expression
M. Lock, K. Botting, R. Tellam, D. Brooks +1 more
2017International Journal of Molecular Sciences30 citations Open access
Semantic Scholar
Akt signaling as a mediator of cardiac adaptation to low birth weight.
Kimberley C. W. Wang, K. Botting, Song Zhang, I. McMillen +2 more
2017Journal of Endocrinology21 citations Open access
Semantic Scholar
Low birth weight activates the renin–angiotensin system, but limits cardiac angiogenesis in early postnatal life
Kimberley C. W. Wang, D. Brooks, B. Summers-Pearce, L. Bobrovskaya +6 more
2015Physiological Reports21 citations Open access
Semantic Scholar
Changes in cardiac troponins with gestational age explain changes in cardiac muscle contractility in the sheep fetus.
G. S. Posterino, S. L. Dunn, K. Botting, William Wang +2 more
2011Journal of applied physiology21 citations
Semantic Scholar
Regulation of microRNA during cardiomyocyte maturation in sheep
J. Morrison, Song Zhang, R. Tellam, D. Brooks +3 more
2015BMC Genomics19 citations Open access
Semantic Scholar
Altered Cardiovascular Defense to Hypotensive Stress in the Chronically Hypoxic Fetus
B. Allison, K. Brain, Y. Niu, A. D. Kane +9 more
2020HYPERTENSION18 citations Open access
Semantic Scholar
MitoQ as an antenatal antioxidant treatment improves markers of lung maturation in healthy and hypoxic pregnancy
M. Lock, K. Botting, B. Allison, Y. Niu +5 more
2023Journal of Physiology17 citations Open access
Semantic Scholar
The Challenge of Weight Stigma for Women in the Preconception Period: Workshop Recommendations for Action from the 5th European Conference on Preconception Health and Care
B. Hill, Alexandra Azzari Wynn-Jones, K. Botting, Emma Hope Cassinelli +7 more
2023International Journal of Environmental Research and Public Health15 citations Open access
Semantic Scholar
Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia.
W. Tong, B. J. Allison, K. Brain, O. Patey +15 more
2025Journal of Physiology14 citations Open access
Semantic Scholar
Isolating adverse effects of glucocorticoids on the embryonic cardiovascular system
Noor E. W. D. Teulings, Tessa A. C. Garrud, Y. Niu, K. Skeffington +14 more
2020The FASEB Journal13 citations Open access
Semantic Scholar
Trans-abdominal in vivo placental vessel occlusion using High Intensity Focused Ultrasound
C. Shaw, I. Rivens, J. Civale, K. Botting +3 more
2018Scientific Reports12 citations Open access
Semantic Scholar
Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model
Alice M. C. Lee, J. Morrison, K. Botting, Tetyana Shandala +1 more
2014International Journal of Endocrinology11 citations Open access
Semantic Scholar
Molecular mechanisms underlying adverse effects of dexamethasone and betamethasone in the developing cardiovascular system
Tessa A. C. Garrud, Noor E. W. D. Teulings, Y. Niu, K. Skeffington +9 more
2023The FASEB Journal8 citations Open access
Semantic Scholar
Translatable mitochondria-targeted protection against programmed cardiovascular dysfunction.
K. Botting, K. Skeffington, Y. Niu, B. Allison +7 more
2020Science Advances8 citations Open access
Semantic Scholar
Embryonic cardioprotection by hydrogen sulphide: studies of isolated cardiac function and ischaemia‐reperfusion injury in the chicken embryo
Rita M. Hess, Y. Niu, Tessa A. C. Garrud, K. Botting +2 more
2020Journal of Physiology8 citations Open access
Semantic Scholar
Maternal and fetal cardiometabolic recovery following ultrasound-guided high-intensity focused ultrasound placental vascular occlusion
C. Shaw, I. Rivens, J. Civale, K. Botting +6 more
2019Journal of the Royal Society Interface8 citations Open access
Semantic Scholar
Maternal and fetal cardiovascular and metabolic effects of intra-operative uterine handling under general anesthesia during pregnancy in sheep
C. Shaw, K. Botting, Y. Niu, C. Lees +1 more
2020Scientific Reports6 citations Open access
Semantic Scholar
Sex-specific effects of in vitro culture and embryo transfer on cardiac growth in sheep offspring
M. Padhee, M. Lock, I. Mcmillen, Song Zhang +8 more
2023Journal of Molecular and Cellular Cardiology Plus4 citations Open access
Semantic Scholar
OC18.06: Fetal and maternal responses to high intensity focused ultrasound (HIFU) ablation of placental vasculature
C. Shaw, J. Civale, K. Botting, Y. Niu +4 more
20153 citations
Semantic Scholar
Does maternal obesity change cardiomyocyte endowment
J. Morrison, C. Suter, K. Botting, J. Nyengaard
20133 citations Open access
Semantic Scholar
Maternal and fetal cardiovascular and metabolic effects of intra-operative uterine handling under general anesthesia during pregnancy in sheep
C. Shaw, K. Botting, Y. Niu, C. Lees +1 more
2020Scientific Reports1 citations Open access
Semantic Scholar
High intensity focused ultrasound (HIFU) ablation of placental vasculature: Feasibility, fetal and maternal safety
C. Shaw, J. Civale, K. Botting, Y. Niu +4 more
20161 citations Open access
Semantic Scholar
OP21.10: Technical and safety considerations for high intensity focused ultrasound (HIFU) non‐invasive placental vascular occlusion
C. Shaw, I. Rivens, J. Civale, K. Botting +3 more
2016Ultrasound in Obstetrics & Gynecology1 citations
Semantic Scholar
Isolating the Long-Term Cardiovascular Effects on Adult Offspring of Human Clinically Relevant Doses of Antenatal Glucocorticoids.
Y. Niu, K. Botting, K. Skeffington, B. Allison +5 more
20161 citations
Semantic Scholar
Does a growth-restricted fetus have fewer cardiomyocytes than a normally grown fetus?
J. Morrison, K. Botting
20121 citations
Semantic Scholar
Weak cardiovascular defence to hypotensive stress in the chronically hypoxic fetus
B. Allison, K. Brain, Y. Niu, A. D. Kane +6 more
20180 citations
Semantic Scholar
At the heart of accelerated old matter
K. Botting, D. Giussani
2017Journal of Physiology0 citations Open access
Semantic Scholar
The mitochondria-targeted antioxidant MitoQ prevents the programming of cardiovascular dysfunction by developmental hypoxia in sheep
K. Botting, K. Skeffington, Y. Niu, B. Allison +6 more
20160 citations
Semantic Scholar
OC15.02: *Obstetric outcomes following non‐invasive high intensity focused ultrasound (HIFU) occlusion of sheep placental vasculature
C. Shaw, I. Rivens, J. Civale, K. Botting +3 more
2016Ultrasound in Obstetrics & Gynecology0 citations
Semantic Scholar
Restriction of placental growth from conception in the sheep results in changes in placental structure and growth factor expression that are independent of whether the fetus becomes hypoxaemic in late gestation
Song Zhang, P. Barker, K. Botting, C. Roberts +3 more
20150 citations
Semantic Scholar
proliferation kinetics in the fetal sheep heart Myocyte enlargement, differentiation, and
S. Jonker, Lu-Bo Zhang, S. Louey, G. Giraud +11 more
20150 citations
Semantic Scholar
model of congenital heart disease before pulmonary vascular remodeling in a lamb Delineating the angiogenic gene expression profile
J. Fineman, Stephen M. Black Schreiber, S. Datar, Peter E. Oishi +22 more
20150 citations
Semantic Scholar
PW295 Is the heart of the IUGR fetus hypoxic in early gestation
Michelle Tie, K. Botting, Song Zhang, C. Mcmillen +3 more
20140 citations
Semantic Scholar

Frequent co-authors

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D. Giussani×24
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D. Giussani — researcher profile on SciRah
J. Morrison×22
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J. Morrison — researcher profile on SciRah
Y. Niu×21
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Y. Niu — researcher profile on SciRah
C. Shaw×12
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C. Shaw — researcher profile on SciRah

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Song Zhang — researcher profile on SciRah

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K. Brain — researcher profile on SciRah

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C. Lees — researcher profile on SciRah

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N. Itani — researcher profile on SciRah

K. Skeffington×9

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K. Skeffington — researcher profile on SciRah

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B. Allison — researcher profile on SciRah

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I. Mcmillen — researcher profile on SciRah

Kimberley C. W. Wang×7

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Kimberley C. W. Wang — researcher profile on SciRah