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H. Janes · SciRah

Researcher profile · Semantic Scholar

H. Janes

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H. Janes — researcher profile on SciRah

h-index: 44
Works: 135
Citations: 14K

Most-cited papers

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial
B. Haynes, P. Gilbert, M. McElrath, S. Zolla-Pazner +39 more
2012New England Journal of Medicine1,727 citations Open access
Semantic Scholar
Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine
Scott M. Hammer, M. Sobieszczyk, H. Janes, S. Karuna +26 more
2013New England Journal of Medicine591 citations Open access
Semantic Scholar
Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine
A. Falsey, M. Sobieszczyk, I. Hirsch, Stephanie Sproule +41 more
2021New England Journal of Medicine581 citations Open access
Semantic Scholar
Assessing the Clinical Impact of Risk Prediction Models With Decision Curves: Guidance for Correct Interpretation and Appropriate Use.
K. Kerr, Marshall D. Brown, Ke-Hao Zhu, H. Janes
2016Journal of Clinical Oncology571 citations Open access
Semantic Scholar
Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase
H. E. El Sahly, L. Baden, B. Essink, Susanne Doblecki-Lewis +34 more
2021New England Journal of Medicine500 citations Open access
Semantic Scholar
Net Reclassification Indices for Evaluating Risk-Prediction Instruments: A Critical Review
K. Kerr, Zhe-Yu Wang, H. Janes, R. McClelland +2 more
2014Epidemiology458 citations Open access
Semantic Scholar
Vaccine Efficacy of ALVAC-HIV and Bivalent Subtype C gp120/MF59 in Adults
G. Gray, L. Bekker, F. Laher, M. Malahleha +57 more
2021New England Journal of Medicine191 citations Open access
Semantic Scholar
Measuring the Performance of Markers for Guiding Treatment Decisions
H. Janes, M. Pepe, P. Bossuyt, W. Barlow
2011Annals of Internal Medicine155 citations Open access
Semantic Scholar
Optimizing vaccine allocation for COVID-19 vaccines shows the potential role of single-dose vaccination
L. Matrajt, Julia Eaton, Tiffany Leung, Dobromir T. Dimitrov +3 more
2021Nature Communications122 citations Open access
Semantic Scholar
FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial.
Shuying S. Li, P. Gilbert, G. Tomaras, G. Kijak +30 more
2014Journal of Clinical Investigation105 citations Open access
Semantic Scholar
Antinucleocapsid Antibodies After SARS-CoV-2 Infection in the Blinded Phase of the Randomized, Placebo-Controlled mRNA-1273 COVID-19 Vaccine Efficacy Clinical Trial
D. Follmann, H. Janes, O. Buhule, Hong-Hong Zhou +9 more
2022Annals of Internal Medicine104 citations Open access
Semantic Scholar
COVID-19 vaccines that reduce symptoms but do not block infection need higher coverage and faster rollout to achieve population impact
David A. Swan, C. Bracis, H. Janes, Mia R. Moore +7 more
2020Scientific Reports96 citations Open access
Semantic Scholar
Clinical Endpoints for Evaluating Efficacy in COVID-19 Vaccine Trials
D. Mehrotra, H. Janes, T. Fleming, P. Annunziato +24 more
2020Annals of Internal Medicine95 citations Open access
Semantic Scholar
Net risk reclassification p values: valid or misleading?
M. Pepe, H. Janes, Christopher I. Li
2014Journal of the National Cancer Institute85 citations Open access
Semantic Scholar
An Ad5-vectored HIV-1 vaccine elicits cell-mediated immunity but does not affect disease progression in HIV-1-infected male subjects: results from a randomized placebo-controlled trial (the Step study).
D. Fitzgerald, H. Janes, Michael N. Robertson, R. Coombs +5 more
2011Journal of Infectious Diseases84 citations Open access
Semantic Scholar
Vaccine-induced gag-specific T cells are associated with reduced viremia after HIV-1 infection.
H. Janes, D. Friedrich, A. Krambrink, Rebecca J. Smith +8 more
2013Journal of Infectious Diseases77 citations Open access
Semantic Scholar
Impact of Herpes Simplex Virus Type 2 on HIV-1 acquisition and progression in an HIV vaccine trial (the Step Study)
R. Barnabas, J. Wasserheit, Yun-Da Huang, H. Janes +7 more
2011Journal of Acquired Immune Deficiency Syndromes77 citations Open access
Semantic Scholar
Early Phase Studies of Biomarkers: What Target Sensitivity and Specificity Values Might Confer Clinical Utility?
M. Pepe, H. Janes, Christopher I. Li, P. Bossuyt +2 more
2016Clinical Chemistry76 citations Open access
Semantic Scholar
Strengthening the Reporting of Genetic Risk Prediction Studies (GRIPS): Explanation and Elaboration
A. C. Janssens, J. Ioannidis, Sara R. Bedrosian, P. Boffetta +21 more
2011European Journal of Epidemiology76 citations Open access
Semantic Scholar
Preventing HIV-1 Infection in Women using Oral Pre-Exposure Prophylaxis: A Meta-analysis of Current Evidence
B. Hanscom, H. Janes, P. Guarino, Ying Huang +5 more
2016Journal of Acquired Immune Deficiency Syndromes68 citations Open access
Semantic Scholar
Analysis of HLA A*02 Association with Vaccine Efficacy in the RV144 HIV-1 Vaccine Trial
A. Gartland, Sue S. Li, J. McNevin, G. Tomaras +46 more
2014Journal of Virology66 citations Open access
Semantic Scholar
An Approach to Evaluating and Comparing Biomarkers for Patient Treatment Selection
H. Janes, Marshall D. Brown, Ying Huang, M. Pepe
2014The International Journal of Biostatistics62 citations Open access
Semantic Scholar
Assessing Treatment-Selection Markers using a Potential Outcomes Framework
Ying Huang, P. Gilbert, H. Janes
2012Biometrics61 citations Open access
Semantic Scholar
A Randomized Trial Evaluating the Prophylactic Activity of DSM265 Against Preerythrocytic Plasmodium falciparum Infection During Controlled Human Malarial Infection by Mosquito Bites and Direct Venous Inoculation
S. Murphy, E. Duke, K. Shipman, Ryan Jensen +21 more
2018Journal of Infectious Diseases51 citations Open access
Semantic Scholar
HIV-1 infections with multiple founders are associated with higher viral loads than infections with single founders
H. Janes, J. Herbeck, S. Tovanabutra, Rasmi Thomas +19 more
2015Nature Medicine45 citations Open access
Semantic Scholar
Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial
David C. Benkeser, D. Montefiori, A. McDermott, Y. Fong +41 more
2023Science Translational Medicine44 citations Open access
Semantic Scholar
Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial
G. Pantaleo, H. Janes, S. Karuna, S. Grant +17 more
2019The Lancet HIV40 citations Open access
Semantic Scholar
Examining protective effects of SARS-CoV-2 neutralizing antibodies after vaccination or monoclonal antibody administration
D. Follmann, Meagan P. O'Brien, J. Fintzi, M. Fay +20 more
2023Nature Communications39 citations Open access
Semantic Scholar
COVID-19 Vaccines and SARS-CoV-2 Transmission in the Era of New Variants: A Review and Perspective
Jasmine R. Marcelin, A. Pettifor, H. Janes, E. Brown +2 more
2022Open Forum Infectious Diseases36 citations Open access
Semantic Scholar
The Fundamental Difficulty With Evaluating the Accuracy of Biomarkers for Guiding Treatment.
H. Janes, M. Pepe, L. McShane, D. Sargent +1 more
2015Journal of the National Cancer Institute36 citations Open access
Semantic Scholar
Immune correlates analysis of a phase 3 trial of the AZD1222 (ChAdOx1 nCoV-19) vaccine
D. Benkeser, You-Yi Fong, H. Janes, E. J. Kelly +36 more
2023npj Vaccines35 citations Open access
Semantic Scholar
Analysis of the HVTN 702 Phase 2b-3 HIV-1 vaccine trial in South Africa assessing RV144 antibody and T-cell correlates of HIV-1 acquisition risk.
Z. Moodie, One B. Dintwe, Sheetal Sawant, D. Grove +44 more
2022Journal of Infectious Diseases35 citations Open access
Semantic Scholar
MRKAd5 HIV-1 Gag/Pol/Nef Vaccine-Induced T-Cell Responses Inadequately Predict Distance of Breakthrough HIV-1 Sequences to the Vaccine or Viral Load
H. Janes, N. Frahm, A. deCamp, M. Rolland +10 more
2012PLoS ONE35 citations Open access
Semantic Scholar
Have the explosive HIV epidemics in sub-Saharan Africa been driven by higher community viral load?
L. Abu-Raddad, R. Barnabas, H. Janes, H. Weiss +3 more
2013AIDS (London)34 citations Open access
Semantic Scholar
Rapid Development of an Integrated Network Infrastructure to Conduct Phase 3 COVID-19 Vaccine Trials
A. M. Mena Lora, Jessica E. Long, Yun-Da Huang, L. Baden +23 more
2023JAMA Network Open32 citations Open access
Semantic Scholar
Could widespread use of antiviral treatment curb the COVID-19 pandemic? A modeling study
L. Matrajt, E. Brown, M. Cohen, Dobromir T. Dimitrov +1 more
2022BMC Infectious Diseases31 citations Open access
Semantic Scholar
Durability of protection and immunogenicity of AZD1222 (ChAdOx1 nCoV-19) COVID-19 vaccine over 6 months
M. Sobieszczyk, Jill Maaske, A. Falsey, Stephanie Sproule +19 more
2022Journal of Clinical Investigation31 citations Open access
Semantic Scholar
Efficient nonparametric inference on the effects of stochastic interventions under two-phase sampling, with applications to vaccine efficacy trials
N. Hejazi, M. V. van der Laan, H. Janes, P. Gilbert +1 more
2020Biometrics31 citations Open access
Semantic Scholar
Effect of rAd5-Vector HIV-1 Preventive Vaccines on HIV-1 Acquisition: A Participant-Level Meta-Analysis of Randomized Trials
Yun-Da Huang, D. Follmann, M. Nason, Lily Zhang +21 more
2015PLoS ONE29 citations Open access
Semantic Scholar
Weighing the Evidence of Efficacy of Oral PrEP for HIV Prevention in Women in Southern Africa
H. Janes, L. Corey, G. Ramjee, L. Carpp +4 more
2018AIDS Research and Human Retroviruses28 citations Open access
Semantic Scholar
Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial
Shuying S. Li, P. Gilbert, L. Carpp, Chul-woo Pyo +20 more
2019Journal of Virology27 citations Open access
Semantic Scholar
Commentary: Reporting standards are needed for evaluations of risk reclassification.
M. Pepe, H. Janes
2011International Journal of Epidemiology27 citations Open access
Semantic Scholar
Statistical Inference for Net Benefit Measures in Biomarker Validation Studies
T. Marsh, H. Janes, M. Pepe
2019Biometrics25 citations Open access
Semantic Scholar
A Framework for Evaluating Markers Used to Select Patient Treatment
H. Janes, M. Pepe, Ying Huang
2013Medical decision making24 citations Open access
Semantic Scholar
A Deferred-Vaccination Design to Assess Durability of COVID-19 Vaccine Effect After the Placebo Group Is Vaccinated
D. Follmann, J. Fintzi, M. Fay, H. Janes +26 more
2021Annals of Internal Medicine20 citations Open access
Semantic Scholar
Taking stock of the present and looking to the future: Envisioning challenges in the design of future HIV prevention efficacy trials
H. Janes, D. Donnell, P. Gilbert, E. Brown +1 more
2019The Lancet HIV20 citations Open access
Semantic Scholar
Identifying post-menopausal women at elevated risk for epithelial ovarian cancer
N. Urban, Sarah T. Hawley, H. Janes, B. Karlan +12 more
2015Gynecologic Oncology19 citations Open access
Semantic Scholar
Sexually transmitted infections amongst men who have sex with men (MSM) in South Africa
Rujeko Mashingaidze, Z. Moodie, M. Allen, L. Bekker +8 more
2023PLOS Global Public Health18 citations Open access
Semantic Scholar
Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans
L. Zhao, A. Fiore-Gartland, L. Carpp, Kristen W. Cohen +25 more
2020PLoS ONE18 citations Open access
Semantic Scholar
Assessing the Clinical Impact of Risk Models for Opting Out of Treatment
K. Kerr, Marshall D. Brown, T. Marsh, H. Janes
2019Medical decision making18 citations Open access
Semantic Scholar

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