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P. Elsbach · SciRah

Researcher profile · Semantic Scholar

P. Elsbach

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P. Elsbach — researcher profile on SciRah

h-index: 44
Works: 95
Citations: 5,739

Most-cited papers

Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes.
J. Weiss, P. Elsbach, I. Olsson, H. Odeberg
1978Journal of Biological Chemistry426 citations Open access
Semantic Scholar
High-affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopolysaccharide
H. Gazzano-Santoro, J. Parent, L. Grinna, A. Horwitz +5 more
1992Infection and Immunity255 citations Open access
Semantic Scholar
Human bactericidal/permeability-increasing protein and a recombinant NH2-terminal fragment cause killing of serum-resistant gram-negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria.
J. Weiss, P. Elsbach, C. Shu, J. Castillo +3 more
1992Journal of Clinical Investigation227 citations Open access
Semantic Scholar
Role of the bactericidal/permeability-increasing protein in host defence.
P. Elsbach, J. Weiss
1998Current Opinion in Immunology222 citations Open access
Semantic Scholar
The potent anti-Staphylococcus aureus activity of a sterile rabbit inflammatory fluid is due to a 14-kD phospholipase A2.
Y. Weinrauch, P. Elsbach, L. Madsen, A. Foreman +1 more
1996Journal of Clinical Investigation215 citations Open access
Semantic Scholar
Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations.
P. W. Gray, G. Flaggs, S. Leong, Richard J. Gumina +3 more
1989Journal of Biological Chemistry194 citations Open access
Semantic Scholar
Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils
C. E. Ooi, J. Weiss, Martin E. Doerfler, P. Elsbach
1991Journal of Experimental Medicine177 citations Open access
Semantic Scholar
The bactericidal/permeability‐increasing protein (BPI) in antibacterial host defense
P. Elsbach
1998Journal of Leukocyte Biology175 citations Open access
Semantic Scholar
An opsonic function of the neutrophil bactericidal/permeability-increasing protein depends on both its N- and C-terminal domains.
Nicole M. Iovine, P. Elsbach, Jerrold Weiss
1997Proceedings of the National Academy of Sciences of the United States of America162 citations Open access
Semantic Scholar
A 25-kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein.
C. E. Ooi, Jerrold Weiss, P. Elsbach, B. Frangione +1 more
1987Journal of Biological Chemistry143 citations Open access
Semantic Scholar
The bactericidal/permeability-increasing protein (BPI), a potent element in host-defense against gram-negative bacteria and lipopolysaccharide.
P. Elsbach, Jerrold Weiss
1993Immunobiology137 citations Open access
Semantic Scholar
Low concentrations of indomethacin inhibit phospholipase A2 of rabbit polymorphonuclear leukocytes.
L. Kaplan, Jerrold Weiss, P. Elsbach
1978Proceedings of the National Academy of Sciences of the United States of America134 citations Open access
Semantic Scholar
Bactericidal/permeability increasing protein and host defense against gram-negative bacteria and endotoxin.
P. Elsbach, Jerrold Weiss
1993Current Opinion in Immunology133 citations
Semantic Scholar
Structural determinants of the action against Escherichia coli of a human inflammatory fluid phospholipase A2 in concert with polymorphonuclear leukocytes.
Jerrold Weiss, M. Inada, P. Elsbach, R. Crowl
1994Journal of Biological Chemistry129 citations Open access
Semantic Scholar
What is the real role of antimicrobial polypeptides that can mediate several other inflammatory responses?
P. Elsbach
2003Journal of Clinical Investigation125 citations Open access
Semantic Scholar
Lipopolysaccharide (LPS)-binding Proteins BPI and LBP Form Different Types of Complexes with LPS*
P. Tobias, K. Soldau, Nicole M. Iovine, P. Elsbach +1 more
1997Journal of Biological Chemistry121 citations Open access
Semantic Scholar
Resistance of gram-negative bacteria to purified bactericidal leukocyte proteins: relation to binding and bacterial lipopolysaccharide structure.
Jerrold Weiss, Susan Beckerdite-Quagliata, P. Elsbach
1980Journal of Clinical Investigation115 citations Open access
Semantic Scholar
Separation of sublethal and lethal effects of the bactericidal/permeability increasing protein on Escherichia coli.
B. Mannion, Jerrold Weiss, P. Elsbach
1990Journal of Clinical Investigation110 citations Open access
Semantic Scholar
Effect of ACTH, hydrocortisone, and glucagon on plasma nonesterified fatty acid concentration (NEFA) in normal subjects and in patients with liver disease.
D. Dreiling, E. Bierman, A. Debons, P. Elsbach +1 more
1962Metabolism: Clinical and Experimental108 citations
Semantic Scholar
Cell-wall determinants of the bactericidal action of group IIA phospholipase A2 against Gram-positive bacteria.
Amy K. Foreman-Wykert, Y. Weinrauch, P. Elsbach, Jerrold Weiss
1999Journal of Clinical Investigation103 citations Open access
Semantic Scholar
The Carboxyl-terminal Domain of Closely Related Endotoxin-binding Proteins Determines the Target of Protein-Lipopolysaccharide Complexes*
Nicole M. Iovine, Joshua S. Eastvold, P. Elsbach, J. Weiss +1 more
2002Journal of Biological Chemistry91 citations Open access
Semantic Scholar
Salt and water metabolism during weight reduction.
P. Elsbach, I. L. Schwartz
1961Metabolism: Clinical and Experimental90 citations
Semantic Scholar
Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli.
Ofer Levy, C. E. Ooi, Jerrold Weiss, R. Lehrer +1 more
1994Journal of Clinical Investigation89 citations Open access
Semantic Scholar
The role of lipopolysaccharides in the action of the bactericidal/permeability-increasing neutrophil protein on the bacterial envelope.
Jerrold Weiss, K. Muello, M. Victor, P. Elsbach
1984Journal of Immunology86 citations
Semantic Scholar
Human granulocytes express a 55-kDa lipopolysaccharide-binding protein on the cell surface that is identical to the bactericidal/permeability-increasing protein.
A. Weersink, K. V. van Kessel, M. E. Van Den Tol, J. V. van Strijp +4 more
1993Journal of Immunology80 citations Open access
Semantic Scholar
Extracellular accumulation of potently microbicidal bactericidal/permeability-increasing protein and p15s in an evolving sterile rabbit peritoneal inflammatory exudate.
Y. Weinrauch, A. Foreman, Chen Shu, Kol A. Zarember +3 more
1995Journal of Clinical Investigation78 citations Open access
Semantic Scholar
Antibacterial 15-kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins.
Ofer Levy, Jerrold Weiss, Kol A. Zarember, C. E. Ooi +1 more
1993Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Increased synthesis of phospholipid during phagocytosis.
P. Elsbach, S. Levy
1968Journal of Clinical Investigation77 citations Open access
Semantic Scholar
Innate immunity: from plants to humans.
N. Borregaard, P. Elsbach, T. Ganz, P. Garred +1 more
2000Immunology today (Amsterdam. Regular ed.)76 citations
Semantic Scholar
Role of charge and hydrophobic interactions in the action of the bactericidal/permeability-increasing protein of neutrophils on gram-negative bacteria.
Jerrold Weiss, M. Victor, P. Elsbach
1983Journal of Clinical Investigation71 citations Open access
Semantic Scholar
EARLY AND DISCRETE CHANGES IN PERMEABILITY OF ESCHERICHIA COLI AND CERTAIN OTHER GRAM-NEGATIVE BACTERIA DURING KILLING BY GRANULOCYTES
S. Beckerdite, C. Mooney, Jerrold Weiss, R. Franson +1 more
1974Journal of Experimental Medicine68 citations Open access
Semantic Scholar
Antibacterial proteins of granulocytes differ in interaction with endotoxin. Comparison of bactericidal/permeability-increasing protein, p15s, and defensins.
Ofer Levy, C. H. Raymond Ooi, P. Elsbach, Martin E. Doerfler +2 more
1995Journal of Immunology66 citations
Semantic Scholar
Effect of lipopolysaccharide (LPS) chain length on interactions of bactericidal/permeability-increasing protein and its bioactive 23-kilodalton NH2-terminal fragment with isolated LPS and intact Proteus mirabilis and Escherichia coli
C. Capodici, Shu Chen, Z. Sidorczyk, P. Elsbach +1 more
1994Infection and Immunity66 citations Open access
Semantic Scholar
Separation of sublethal and lethal effects of polymorphonuclear leukocytes on Escherichia coli.
B. Mannion, Jerrold Weiss, P. Elsbach
1990Journal of Clinical Investigation63 citations Open access
Semantic Scholar
COMPOSITION AND SYNTHESIS OF LIPIDS IN RESTING AND PHAGOCYTIZING LEUKOCYTES
P. Elsbach
1959Journal of Experimental Medicine61 citations Open access
Semantic Scholar
A recombinant amino terminal fragment of bactericidal/permeability‐increasing protein inhibits the induction of leukocyte responses by LPS
K. Mészáros, J. Parent, H. Gazzano-Santoro, R. Little +8 more
1993Journal of Leukocyte Biology60 citations
Semantic Scholar
Phospholipase A activity associated with membranes of human polymorphonuclear leucocytes.
R. Franson, J. Weiss, L. Martin, J. Spitznagel +1 more
1977Biochemical Journal60 citations Open access
Semantic Scholar
Preferential binding of the neutrophil cytoplasmic granule-derived bactericidal/permeability increasing protein to target bacteria. Implications and use as a means of purification.
B. Mannion, E. Kalatzis, Jerrold Weiss, P. Elsbach
1989Journal of Immunology59 citations
Semantic Scholar
Phospholipid metabolism by phagocytic cells. VI. Observations on the fate of phospholipids of granulocytes and ingested Escherichia coli during phagocytosis.
P. Elsbach, J. Goldman, P. Patriarca
1972Biochimica et Biophysica Acta54 citations
Semantic Scholar
Phagocytosis of bacteria and phospholipid degradation.
P. Elsbach, Jerrold Weiss
1988Biochimica et Biophysica Acta52 citations
Semantic Scholar
Oxygen-dependent and oxygen-independent mechanisms of microbicidal activity of neutrophils.
P. Elsbach, J. Weiss
1985Immunology Letters52 citations
Semantic Scholar
STUDIES ON THE SODIUM AND POTASSIUM TRANSPORT IN RABBIT POLYMORPHONUCLEAR LEUKOCYTES
P. Elsbach, I. L. Schwartz
1959The Journal of General Physiology52 citations Open access
Semantic Scholar
THE INTERACTION IN VITRO BETWEEN POLYMORPHONUCLEAR LEUKOCYTES AND MYCOPLASMA
M. Simberkoff, P. Elsbach
1971Journal of Experimental Medicine51 citations Open access
Semantic Scholar
Deacylation of Lipopolysaccharide in Whole Escherichia coli during Destruction by Cellular and Extracellular Components of a Rabbit Peritoneal Inflammatory Exudate*
S. S. Katz, Y. Weinrauch, R. Munford, P. Elsbach +1 more
1999Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Prospects for use of recombinant BPI in the treatment of gram-negative bacterial infections.
P. Elsbach, J. Weiss
1995Infectious agents and disease43 citations
Semantic Scholar
Reversible envelope effects during and after killing of Escherichia coli w by a highly-purified rabbit polymorpho-nuclear leukocyte fraction.
J. Weiss, C. Franson, K. Schmeidler, P. Elsbach
1976Biochimica et Biophysica Acta43 citations
Semantic Scholar
Sensitivity of K1-Encapsulated Escherichia coli to Killing by the Bactericidal/Permeability-Increasing Protein of Rabbit and Human Neutrophils
J. Weiss, M. Victor, A. Cross, P. Elsbach
1982Infection and Immunity37 citations Open access
Semantic Scholar
Phospholipid metabolism by phagocytic cells. VII. The degradation and utilization of phospholipids of various microbial species by rabbit granulocytes.
P. Patriarca, S. Beckerdite, Penelope K. Pettis, P. Elsbach
1972Biochimica et Biophysica Acta37 citations
Semantic Scholar
Isolation of two isoforms of a novel 15-kDa protein from rabbit polymorphonuclear leukocytes that modulate the antibacterial actions of other leukocyte proteins.
C. E. Ooi, Jerrold Weiss, Ofer Levy, P. Elsbach
1990Journal of Biological Chemistry36 citations
Semantic Scholar
Host Defense Functions of Proteolytically Processed and Parent (Unprocessed) Cathelicidins of Rabbit Granulocytes
Kol A. Zarember, S. S. Katz, B. F. Tack, L. Doukhan +2 more
2002Infection and Immunity34 citations Open access
Semantic Scholar

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