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R. Spengler · SciRah

Researcher profile · Semantic Scholar

R. Spengler

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R. Spengler — researcher profile on SciRah

h-index: 18
Works: 31
Citations: 1,774

Most-cited papers

Structure and activity of putative intronic miRNA promoters.
A. M. Monteys, R. Spengler, Ji Wan, L. Tecedor +3 more
2010RNA: A publication of the RNA Society398 citations Open access
Semantic Scholar
Transcriptome-wide Discovery of microRNA Binding Sites in Human Brain
R. Boudreau, Peng Jiang, B. Gilmore, R. Spengler +5 more
2014Neuron213 citations Open access
Semantic Scholar
The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research
Saumya Das, K. Ansel, M. Bitzer, X. Breakefield +139 more
2019Cell195 citations Open access
Semantic Scholar
Adenosine deamination in human transcripts generates novel microRNA binding sites
G. Borchert, B. Gilmore, R. Spengler, Yi Xing +3 more
2009Human Molecular Genetics145 citations Open access
Semantic Scholar
Comprehensive multi-center assessment of accuracy, reproducibility and bias of small RNA-seq methods for quantitative miRNA profiling
M. Giraldez, R. Spengler, A. Etheridge, Paula M. Godoy +23 more
2018Nature Biotechnology118 citations Open access
Semantic Scholar
Phospho‐RNA‐seq: a modified small RNA‐seq method that reveals circulating mRNA and lncRNA fragments as potential biomarkers in human plasma
MD Giraldez, R. Spengler, A. Etheridge, A. Goicochea +4 more
2019EMBO Journal94 citations Open access
Semantic Scholar
Rational design of therapeutic siRNAs: minimizing off-targeting potential to improve the safety of RNAi therapy for Huntington's disease.
R. Boudreau, R. Spengler, B. Davidson
2011Molecular Therapy89 citations Open access
Semantic Scholar
Functional microRNAs and target sites are created by lineage-specific transposition.
R. Spengler, Clayton K Oakley, B. Davidson
2014Human Molecular Genetics67 citations Open access
Semantic Scholar
Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma
C. Haring, C. Bhambhani, C. Brummel, B. Jewell +13 more
2021OncoTarget66 citations Open access
Semantic Scholar
siSPOTR: a tool for designing highly specific and potent siRNAs for human and mouse
R. Boudreau, R. Spengler, R. Hylock, Brandyn J. Kusenda +3 more
2012Nucleic Acids Research62 citations Open access
Semantic Scholar
Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP
R. Spengler, Xiaoming Zhang, Congsheng Cheng, J. McLendon +4 more
2016Nucleic Acids Research59 citations Open access
Semantic Scholar
The long non-coding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease gene-dependent toxicities
Congsheng Cheng, R. Spengler, Megan S. Keiser, A. M. Monteys +3 more
2018Human Molecular Genetics49 citations Open access
Semantic Scholar
Rational Design Leads to More Potent RNA Interference Against Hepatitis B Virus: Factors Effecting Silencing Efficiency
Kathy Keck, E. Volper, R. Spengler, Dang D. Long +3 more
2008Molecular Therapy44 citations Open access
Semantic Scholar
Erratum: Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling
MD Giraldez, R. Spengler, A. Etheridge, Paula M. Godoy +23 more
2018Nature Biotechnology42 citations Open access
Semantic Scholar
Artificial miRNAs Targeting Mutant Huntingtin Show Preferential Silencing In Vitro and In Vivo.
A. M. Monteys, M. Wilson, R. Boudreau, R. Spengler +1 more
2015Molecular Therapy: Nucleic Acids35 citations Open access
Semantic Scholar
Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics
Hiroshi I. Suzuki, R. Spengler, G. Grigelioniene, Tatsuya Kobayashi +1 more
2018Nature Genetics23 citations Open access
Semantic Scholar
Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain
A. M. Monteys, R. Spengler, B. Dufour, Matt S. Wilson +4 more
2014Nucleic Acids Research22 citations Open access
Semantic Scholar
Human-specific microRNA regulation of FOXO1: implications for microRNA recognition element evolution.
Hayley S. McLoughlin, Ji Wan, R. Spengler, Yi Xing +1 more
2014Human Molecular Genetics20 citations Open access
Semantic Scholar
Transcriptome changes in stages of non-alcoholic fatty liver disease
J. Aljabban, Michael Rohr, S. Syed, Kamal Khorfan +9 more
2022World Journal of Hepatology19 citations Open access
Semantic Scholar
Men who inject opioids exhibit altered tRNA-Gly-GCC isoforms in semen
G. Gornalusse, R. Spengler, E. Sandford, Yeseul Kim +4 more
2023Molecular human reproduction9 citations Open access
Semantic Scholar
Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts
S. Ramachandran, Stephanie L. Coffin, Tin-Yun Tang, Chintan D. Jobaliya +2 more
2016Human Molecular Genetics7 citations Open access
Semantic Scholar
Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop
Roger P. Alexander, R. Kitchen, J. Tosar, M. Roth +15 more
2022Frontiers in Genetics3 citations Open access
Semantic Scholar
Abstract 17984: No Longer Silent: A Synonymous Coding SNP Modifying a Novel MicroRNA-24:SCN5A Interaction Associates With Non-Arrhythmic Death in Heart Failure
R. Boudreau, R. Spengler, Jessica M. Skeie, Xiaoming Zhang +11 more
20151 citations
Semantic Scholar
Peer Review #1 of "SPMLMI: predicting lncRNA–miRNA interactions in humans using a structural perturbation method (v0.2)"
Ming-Min Xu, Yuan-Yuan Chen, Wei-Qi Lu, Ling-Peng Kong +237 more
20210 citations Open access
Semantic Scholar
Abstract IA23: Phospho-RNA-seq: A liquid biopsy approach for cell-free mRNA/lncRNA profiling
M. Giraldez, R. Spengler, A. Etheridge, A. Goicochea +4 more
2020Oral Presentations - Invited Abstracts0 citations
Semantic Scholar
Phospho-sRNA-seq reveals extracellular mRNA/lncRNA fragments as potential biomarkers in human plasma
M. Giraldez, R. Spengler, A. Etheridge, A. Goicochea +4 more
2019bioRxiv0 citations Open access
Semantic Scholar
Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts.
S. Ramachandran, Stephanie L. Coffin, Tin-Yun Tang, Chintan D. Jobaliya +2 more
2016Human Molecular Genetics0 citations
Semantic Scholar
Abstract 20207: Deciphering and Exploiting MicroRNA-Target Interactomes in Human Cardiac Tissues
Congsheng Cheng, R. Spengler, Frances L. Johnson, S. G. Drakos +4 more
20140 citations
Semantic Scholar
Mechanisms Of MicroRNA evolution, regulation and function: computational insight, biological evaluation and practical application
R. Spengler
20130 citations Open access
Semantic Scholar
Abstract 18910: Deciphering and Exploiting Transcriptome-Wide MicroRNA Binding Profiles in Human Tissues
R. Boudreau, Peng Jiang, B. Gilmore, R. Spengler +4 more
2013Circulation0 citations
Semantic Scholar
"siSPOTTR: Improving Off-Target Prediction in RNAi Design"
R. Spengler
20110 citations
Semantic Scholar

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