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X. Brands · SciRah

Researcher profile · Semantic Scholar

X. Brands

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X. Brands — researcher profile on SciRah

h-index: 14
Works: 36
Citations: 621

Most-cited papers

Disruptions of Anaerobic Gut Bacteria Are Associated with Stroke and Post-stroke Infection: a Prospective Case–Control Study
B. Haak, W. Westendorp, T. S. R. van Engelen, X. Brands +10 more
2020Translational Stroke Research122 citations Open access
Semantic Scholar
Thrombocytopenia Impairs Host Defense During Murine Streptococcus pneumoniae Pneumonia
F. E. van den Boogaard, M. Schouten, S. D. de Stoppelaar, J. J. Roelofs +4 more
2015Critical Care Medicine61 citations Open access
Semantic Scholar
Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti‐inflammatory and antimicrobial effects in murine pneumococcal pneumonia
F. E. van den Boogaard, X. Brands, M. Schultz, M. Levi +3 more
2011Journal of Thrombosis and Haemostasis59 citations Open access
Semantic Scholar
Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia
X. Brands, B. Haak, Augustijn M. Klarenbeek, N. A. Otto +5 more
2020Frontiers in Immunology46 citations Open access
Semantic Scholar
The host response in different aetiologies of community-acquired pneumonia
A. Schuurman, T. Reijnders, T. S. R. van Engelen, Valentine Léopold +16 more
2022EBioMedicine31 citations Open access
Semantic Scholar
Bacterial and Viral Respiratory Tract Microbiota and Host Characteristics in Adults With Lower Respiratory Tract Infections: A Case-Control Study
B. Haak, X. Brands, M. Davids, H. Peters-Sengers +8 more
2021Clinical Infectious Diseases26 citations Open access
Semantic Scholar
An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration
X. Brands, B. Haak, Augustijn M. Klarenbeek, J. Butler +9 more
2021Genome Medicine24 citations Open access
Semantic Scholar
Butyrate-producing gut bacterium Faecalibacterium prausnitzii protects against bacterial pneumonia
R. F. J. Kullberg, Christine C. A. van Linge, A. D. de Vos, X. Brands +10 more
2025European Respiratory Journal22 citations Open access
Semantic Scholar
Mast cells impair host defense during murine Streptococcus pneumoniae pneumonia.
F. E. van den Boogaard, X. Brands, J. Roelofs, R. de Beer +3 more
2014Journal of Infectious Diseases18 citations Open access
Semantic Scholar
Quantifying immune dysregulation in pneumonia and sepsis with a parsimonious machine-learning model: a multicohort analysis across care settings and reanalysis of a hydrocortisone randomised controlled trial.
Erik H. A. Michels, P. Dequin, J. Butler, Antoine Guillon +24 more
2026The Lancet Respiratory Medicine17 citations
Semantic Scholar
The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis
H. Khan, X. Brands, Simona Aufiero, A. J. Hoogendijk +9 more
2020Critical Care17 citations Open access
Semantic Scholar
Nebulized Recombinant Human Tissue Factor Pathway Inhibitor Attenuates Coagulation and Exerts Modest Anti-inflammatory Effects in Rat Models of Lung Injury
F. E. van den Boogaard, J. Hofstra, X. Brands, Marcel Levi +5 more
2017Journal of Aerosol Medicine17 citations Open access
Semantic Scholar
Plasma Ferritin as Marker of Macrophage Activation-Like Syndrome in Critically Ill Patients With Community-Acquired Pneumonia
X. Brands, Floris M. C. de Vries, F. Uhel, B. Haak +9 more
2021Critical Care Medicine14 citations Open access
Semantic Scholar
Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection
Wanhai Qin, X. Brands, C. van 't Veer, A. D. de Vos +4 more
2021PLoS Pathogens14 citations Open access
Semantic Scholar
Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by Escherichia coli
Wanhai Qin, X. Brands, Hisatake Matsumoto, J. Butler +5 more
2021Cells14 citations Open access
Semantic Scholar
Protease-Activated Receptor 2 Facilitates Bacterial Dissemination in Pneumococcal Pneumonia
F. E. van den Boogaard, X. Brands, J. Duitman, S. D. de Stoppelaar +7 more
2018Journal of Infectious Diseases14 citations Open access
Semantic Scholar
Lymphopenia is associated with broad host response aberrations in community-acquired pneumonia.
Susanne E. Doeleman, T. Reijnders, S. Joosten, A. Schuurman +15 more
2024Journal of Infection13 citations Open access
Semantic Scholar
Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia
A. Schuurman, J. Butler, Erik H. A. Michels, N. A. Otto +12 more
2023iScience12 citations Open access
Semantic Scholar
Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patients
X. Brands, F. Uhel, L. V. van Vught, M. Wiewel +5 more
2022PLoS ONE12 citations Open access
Semantic Scholar
Rectal bacteriome and virome signatures and clinical outcomes in community-acquired pneumonia: An exploratory study
R. F. J. Kullberg, F. Hugenholtz, X. Brands, C. Kinsella +10 more
2021EClinicalMedicine12 citations Open access
Semantic Scholar
Bronchial Epithelial Tet2 Maintains Epithelial Integrity during Acute Pseudomonas aeruginosa Pneumonia
Wanhai Qin, X. Brands, C. van 't Veer, A. D. de Vos +2 more
2020Infection and Immunity12 citations Open access
Semantic Scholar
The shifting lipidomic landscape of blood monocytes and neutrophils during pneumonia
A. Schuurman, O. Chouchane, J. Butler, H. Peters-Sengers +18 more
2024JCI Insight10 citations Open access
Semantic Scholar
Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalization
R. F. J. Kullberg, X. Brands, Augustijn M. Klarenbeek, J. Butler +6 more
2022iScience9 citations Open access
Semantic Scholar
Intracellular pyruvate levels positively correlate with cytokine production capacity in tolerant monocytes from patients with pneumonia.
N. A. Otto, J. Butler, A. Schuurman, X. Brands +10 more
2022Biochimica et Biophysica Acta - Molecular Basis of Disease7 citations Open access
Semantic Scholar
Endothelial glycocalyx degradation and its association with clinical outcomes and host response aberrations in community-acquired pneumonia across different care settings
Hui Wang, Erik H. A. Michels, M. Cai, J. Butler +13 more
2026Critical Care5 citations Open access
Semantic Scholar
The Plasma Proteome in Community-acquired Pneumonia: Pathophysiology, Outcome and 10-Year Risk.
Erik H. A. Michels, H. Peters-Sengers, J. de Brabander, A. Schuurman +11 more
2025American Journal of Respiratory and Critical Care Medicine3 citations Open access
Semantic Scholar
Association of Hyperferritinemia With Distinct Host Response Aberrations in Patients With Community-Acquired Pneumonia
X. Brands, T. S. R. van Engelen, Floris M. C. de Vries, B. Haak +13 more
2022Journal of Infectious Diseases3 citations Open access
Semantic Scholar
Myeloid cell tet methylcytosine dioxygenase 2 does not affect the host response during gram-negative bacterial pneumonia and sepsis.
Wanhai Qin, X. Brands, C. van 't Veer, A. D. de Vos +2 more
2022Cytokine3 citations Open access
Semantic Scholar
Flagellin induces innate immune genes in bronchial epithelial cells in vivo: Role of TET2
Wanhai Qin, X. Brands, C. Veer, A. F. Vos +2 more
2021Scandinavian Journal of Immunology3 citations Open access
Semantic Scholar
An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration
X. Brands, B. Haak, Augustijn M. Klarenbeek, J. Butler +9 more
2021Genome Medicine2 citations Open access
Semantic Scholar
The proteomic landscape of blood monocytes in community-acquired pneumonia
O. Chouchane, Erik H. A. Michels, Giuseppe G. F. Leite, A. D. de Vos +12 more
2025European Respiratory Journal1 citations Open access
Semantic Scholar
DNA Methyltransferase 3b in Myeloid Cells Does Not Affect the Acute Immune Response in the Airways during Pseudomonas Pneumonia
Wanhai Qin, X. Brands, C. van 't Veer, A. D. de Vos +2 more
2022Cells1 citations Open access
Semantic Scholar
Corrigendum: Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia
X. Brands, B. Haak, Augustijn M. Klarenbeek, N. A. Otto +5 more
2020Frontiers in Immunology1 citations
Semantic Scholar
PB1153 Association of Von Willebrand Factor levels with the host response in community-acquired pneumonia
Yi-Ding Tang, Aymeric Moffelein, Daniëlle Kruijswijk, W. Kopatz +9 more
2026Research and Practice in Thrombosis and Haemostasis0 citations Open access
Semantic Scholar
Programmed death-ligand 1 links with inflammatory and endothelial activation in pneumonia
Evelien Reijnders, S. Joosten, Erik H. A. Michels, A. Schuurman +15 more
2026ERJ Open Research0 citations Open access
Semantic Scholar
Nebulized recombinant human Tissue Factor Pathway Inhibitor attenuates coagulation and inflammation in rat models of direct and indirect lung injury
F. E. van den Boogaard, J. Hofstra, X. Brands, M. Levi +5 more
20150 citations
Semantic Scholar

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