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P. Chmielarz · SciRah

Researcher profile · Semantic Scholar

P. Chmielarz

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P. Chmielarz — researcher profile on SciRah

h-index: 15
Works: 45
Citations: 876

Most-cited papers

Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases
J. Konovalova, D. Gerasymchuk, Ilmari Parkkinen, P. Chmielarz +1 more
2019International Journal of Molecular Sciences179 citations Open access
Semantic Scholar
Neuroprotective Effects of Pomegranate Juice against Parkinson’s Disease and Presence of Ellagitannins-Derived Metabolite—Urolithin A—In the Brain
M. Kujawska, M. Jourdes, Monika Kurpik, M. Szulc +7 more
2019International Journal of Molecular Sciences137 citations Open access
Semantic Scholar
Dicer and microRNAs protect adult dopamine neurons
P. Chmielarz, J. Konovalova, Syeda Sadia Najam, Heike Alter +6 more
2017Cell Death and Disease90 citations Open access
Semantic Scholar
Back and to the Future: From Neurotoxin‐Induced to Human Parkinson's Disease Models
M. Airavaara, Ilmari Parkkinen, J. Konovalova, Katrina Albert +2 more
2020Current Protocols in Neuroscience53 citations Open access
Semantic Scholar
Neurotrophic factors for disease-modifying treatments of Parkinson's disease: gaps between basic science and clinical studies
P. Chmielarz, M. Saarma
2020Pharmacological Reports52 citations Open access
Semantic Scholar
GDNF/RET signaling pathway activation eliminates Lewy Body pathology in midbrain dopamine neurons
P. Chmielarz, Ş. Er, J. Konovalova, Laura Bandrés +6 more
2019bioRxiv46 citations Open access
Semantic Scholar
Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo
Katrina Albert, D. Raymundo, A. Panhelainen, Ave Eesmaa +16 more
2021Molecular Therapy41 citations Open access
Semantic Scholar
Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects.
P. Zajdel, T. Kos, Krzysztof Marciniec, G. Satała +15 more
2018European journal of medicinal chemistry41 citations Open access
Semantic Scholar
MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System
Emmi Pakarinen, T. Danilova, V. Võikar, P. Chmielarz +4 more
2020eNeuro35 citations Open access
Semantic Scholar
Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism
G. Kreiner, K. Rafa-Zabłocka, J. Barut, P. Chmielarz +5 more
2019Scientific Reports29 citations Open access
Semantic Scholar
Inactivation of Glucocorticoid Receptor in Noradrenergic System Influences Anxiety- and Depressive-Like Behavior in Mice
P. Chmielarz, J. Kuśmierczyk, R. Parlato, G. Schütz +2 more
2013PLoS ONE29 citations Open access
Semantic Scholar
Gender differences in genetic mouse models evaluated for depressive-like and antidepressant behavior
G. Kreiner, P. Chmielarz, A. Roman, I. Nalepa
2013Pharmacological Reports22 citations
Semantic Scholar
Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons.
Ş. Er, Irena Hlushchuk, M. Airavaara, P. Chmielarz +1 more
2020Journal of Visualized Experiments20 citations Open access
Semantic Scholar
Functionally distinctive Ptch receptors establish multimodal Hedgehog signaling in the tooth epithelial stem cell niche
Martin Binder, P. Chmielarz, P. Mckinnon, Leah C. Biggs +2 more
2019Stem Cells17 citations Open access
Semantic Scholar
Disruption of glucocorticoid receptors in the noradrenergic system leads to BDNF up-regulation and altered serotonergic transmission associated with a depressive-like phenotype in female GR(DBHCre) mice.
P. Chmielarz, G. Kreiner, M. Kot, A. Zelek-Molik +4 more
2015Pharmacology, Biochemistry and Behavior15 citations
Semantic Scholar
Chronic restraint stress induces changes in the cerebral Galpha 12/13 and Rho-GTPase signaling network
K. Rafa-Zabłocka, A. Zelek-Molik, Beata Tepper, P. Chmielarz +3 more
2021Pharmacological Reports11 citations Open access
Semantic Scholar
Depressive-like immobility behavior and genotype × stress interactions in male mice of selected strains
P. Chmielarz, G. Kreiner, J. Kuśmierczyk, M. Kowalska +3 more
2016Stress11 citations Open access
Semantic Scholar
Alpha-synuclein preformed fibrils: a tool to understand Parkinson’s disease and develop disease modifying therapy
P. Chmielarz, A. Domanskyi
2021Neural Regeneration Research9 citations Open access
Semantic Scholar
Selective ablation of glucocorticoid receptors in the noradrenergic system affects evening corticosterone levels in a sex-dependent manner
P. Chmielarz, G. Kreiner, I. Nalepa
2015Pharmacological Reports9 citations
Semantic Scholar
Investigating the potential effects of α-synuclein aggregation on susceptibility to chronic stress in a mouse Parkinson’s disease model
A. Alwani, Katarzyna Maziarz, Gabriela Burda, Monika Jankowska-Kiełtyka +9 more
2023Pharmacological Reports6 citations Open access
Semantic Scholar
Trehalose-releasing nanogels reduce α-synuclein-induced Lewy body-like inclusions in primary mouse hippocampal neurons.
Ali Maruf, D. Gerasymchuk, Irena Hlushchuk, Ş. Er +5 more
2025Journal of materials chemistry. B4 citations Open access
Semantic Scholar
GDNF reduces fibril-induced early-stage alpha-synuclein pathology after delivery of 20S proteasome inhibitor lactacystin.
Ş. Er, Ilmari Parkkinen, Karolina Trepczyk, Anna Seelbach +7 more
2025European Journal of Pharmaceutical Sciences4 citations Open access
Semantic Scholar
Cell Culture Media, Unlike the Presence of Insulin, Affect α-Synuclein Aggregation in Dopaminergic Neurons
Irena Hlushchuk, J. Barut, M. Airavaara, Kelvin C. Luk +2 more
2022Biomolecules4 citations Open access
Semantic Scholar
Beyond KOL management: communities of practice as a new perspective on pharmaceutical market penetration:
Mark Kroes, P. Chmielarz, Lisa Chandler, M. Bergler +1 more
20104 citations
Semantic Scholar
Gender-dependent activity of CYP3A is indirectly modified by GR in the noradrenergic system
M. Kot, G. Kreiner, P. Chmielarz, J. Kuśmierczyk +2 more
2013Pharmacological Reports3 citations
Semantic Scholar
Characterization and evaluation of the ability of graphene quantum dots to affect α-synuclein aggregation in synucleinopathy models
Tuba Oz, A. Alwani, A. Kamińska, B. Jachimska +9 more
2026Science and Technology of Advanced Materials2 citations Open access
Semantic Scholar
The Differential Involvement of α1-Adrenoceptor Subtypes in the Molecular Effects of Antidepressant Drugs
Irena Nalepa, K. Chorążka, Grzegorz Kreiner, Agnieszka Zelek-Molik +8 more
2025International Journal of Molecular Sciences2 citations Open access
Semantic Scholar
Antidepressants Differentially Regulate Intracellular Signaling from α1-Adrenergic Receptor Subtypes In Vitro
P. Chmielarz, J. Kuśmierczyk, K. Rafa-Zabłocka, K. Chorążka +3 more
2021International Journal of Molecular Sciences2 citations Open access
Semantic Scholar
Lack of riluzole efficacy in the progression of the neurodegenerative phenotype in a new conditional mouse model of striatal degeneration
G. Kreiner, K. Rafa-Zabłocka, P. Chmielarz, M. Bagińska +1 more
2017PeerJ1 citations Open access
Semantic Scholar
Peptidomimetics Activating the Proteasome: A New Perspective for Parkinson’s Treatment
Karolina Trepczyk, Ş. Er, Irena Hlushchuk, M. Airavaara +6 more
2025Journal of Medicinal Chemistry0 citations Open access
Semantic Scholar
Carbon-based composite rod as a potential electrode for stimulation of neural tissue: Electrochemical, biological, and stability evaluation
Marcel Zambrzycki, Ryszard Wielowski, K. Sokołowski, M. Gubernat +5 more
2025Chemical Engineering Journal0 citations Open access
Semantic Scholar
Ghrelin receptor agonist rescues motor impairments and protects dopamine neurons in alpha-synuclein aggregation model
K. Maziarz, M. Jankowska-Kiełtyka, J. Barut, P. Chmielarz
2023Neuroscience Applied0 citations Open access
Semantic Scholar
Single, conditional, lentiviral CRISPR/Cas9 vectors for efficient mutagenesis in neurons – a possible new strategy for modeling prodromal Parkinson’s disease
J. Barut, K. Rafa-Zabłocka, P. Chmielarz, A. Domanskyi +4 more
2022Neuroscience Applied0 citations Open access
Semantic Scholar
Ghrelin receptor agonist MK-0677 alleviates motor impairments caused by spreading alpha-synuclein aggregation in bilaterally alpha-synuclein fibrils injected mice
K. Maziarz, M. Jankowska-Kiełtyka, J. Barut, P. Chmielarz
2022Neuroscience Applied0 citations Open access
Semantic Scholar
PKB/AKT attenuates Lewy Body-like pathology in primary neurons via Cathepsins B and D
J. Konovalova, Ş. Er, J. Barut, K. Rafa-Zabłocka +5 more
2022bioRxiv0 citations Open access
Semantic Scholar
Gene delivery for Parkinson's disease
P. Chmielarz, A. Panhelainen, M. Airavaara, A. Domanskyi
20200 citations
Semantic Scholar
Cell transplantation therapy for Parkinson's disease
P. Chmielarz, J. Konovalova, A. Domanskyi
2020Diagnosis and Management in Parkinson's Disease0 citations
Semantic Scholar
Neurotrophic factors for disease-modifying treatments of Parkinson's disease: gaps between basic science and clinical studies
P. Chmielarz, M. Saarma
20200 citations Open access
Semantic Scholar
Constitutive activation of pro-survival pathway ameliorates aggregation of α-synuclein in dopaminergic neurons
J. Konovalova, P. Chmielarz, Ş. Er, A. Domanskyi
20190 citations
Semantic Scholar
Activation of RET tyrosine kinase prevents accumulation of misfolded alpha-synuclein induced by exogenous preformed fibrils
P. Chmielarz, Ş. Er, L. Banders, K. Alberts +3 more
20190 citations
Semantic Scholar
Activation of pro-survival signaling inhibits alpha-synuclein aggregation in dopaminergic neurons
J. Konovalova, P. Chmielarz, Ş. Er, A. Domanskyi
20190 citations
Semantic Scholar
Identification of a factor reducing PFF-induced Lewy Body pathology in dopamine neurons
Ş. Er, P. Chmielarz, J. Konovalova, Laura Bandrés +3 more
20190 citations
Semantic Scholar
Differential susceptibility of the alpha(1)-adrenergic receptor subtypes to antidepressant drugs action: in vitro study
J. Kuśmierczyk, P. Chmielarz, K. Rafa-Zabłocka, M. Kowalska +1 more
20170 citations
Semantic Scholar
Prolonged incubation with desipramine differentially modulate A1A-and A1B-adrenoreceptor signaling in PC12 cells
P. Chmielarz, M. Kowalska, K. Rafa-Zabłocka, I. Nalepa
20150 citations
Semantic Scholar
The lack of glucocorticoid receptor on noradrenergic cells does not influence an inflammatory response after chronic stress
J. Kuśmierczyk, P. Chmielarz, E. Trojan, A. Roman +1 more
20150 citations
Semantic Scholar
P.1.h.012 Changes in alpha(1D)-adrenergic receptor expression and working memory of female mice with selective glucocorticoid receptor ablation
P. Chmielarz, G. Kreiner, A. Zelek-Molik, Irena Nalepa
20130 citations
Semantic Scholar
The influence of conditional inactivation of GR in noradrenergic system on stress related behavior in mice
G. Kreiner, P. Chmielarz, J. Kuśmierczyk, R. Parlato +2 more
20110 citations
Semantic Scholar
P.2.f.002 Conditional inactivation of glucocorticoid receptors in noradrenergic system evokes changes in alpha(1)-adrenoceptors mRNA expression in brain structure-dependent manner
G. Kreiner, A. Zelek-Molik, P. Chmielarz, J. Kuśmierczyk +1 more
20110 citations
Semantic Scholar
P.1.020 Selective ablation of glucocorticoid receptor in noradrenergic system of mice: the influence on brain noradrenergic receptors
P. Chmielarz, G. Kreiner, J. Kusmierczyk, A. Zelek-Molik +3 more
2011European Neuropsychopharmacology0 citations
Semantic Scholar
P.2.d.008 Effects of single and chronic agomelatine administration on Galpha(i) proteins expression in the rat brain
P. Chmielarz, Krzysztof Wieczerzak, A. Zelek-Molik, J. Kuśmierczyk +2 more
20100 citations
Semantic Scholar

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A. Domanskyi×18
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G. Kreiner×16
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I. Nalepa×15
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M. Airavaara×11
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Ş. Er — researcher profile on SciRah

J. Konovalova×10

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