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A. Mode · SciRah

Researcher profile · Semantic Scholar

A. Mode

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A. Mode — researcher profile on SciRah

h-index: 37
Works: 105
Citations: 4,015

Most-cited papers

Sex steroid induced changes in hepatic enzymes.
Jan-Åke Gustafsson, A. Mode, Gunnar Norstedt, P. Skett
1983Annual Review of Physiology313 citations
Semantic Scholar
Imprinting of growth hormone secretion, body growth, and hepatic steroid metabolism by neonatal testosterone.
J. Jansson, S. Ekberg, O. Isaksson, A. Mode +1 more
1985Endocrinology182 citations
Semantic Scholar
Association between plasma level of growth hormone and sex differentiation of hepatic steroid metabolism in the rat.
A. Mode, Jan-Åke Gustafsson, J. Jansson, Staffan Edén +1 more
1982Endocrinology173 citations
Semantic Scholar
Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention.
J. Davies, Pia Kotokorpi, S. Eccles, S. Barnes +8 more
2009Molecular Endocrinology161 citations Open access
Semantic Scholar
Hepatic steroid hydroxylating enzymes are controlled by the sexually dimorphic pattern of growth hormone secretion in normal and dwarf rats
C. Legraverend, A. Mode, T. Wells, I. Robinson +1 more
1992The FASEB Journal149 citations
Semantic Scholar
Continuous infusion of growth hormone feminizes hepatic steroid metabolism in the rat.
A. Mode, G. Norstedt, B. Šimić, P. Eneroth +1 more
1981Endocrinology149 citations
Semantic Scholar
Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion.
Catherine Legraverend, A. Mode, S. Westin, A. Ström +3 more
1992Molecular Endocrinology136 citations
Semantic Scholar
Regulation of sexual differentiation in drug and steroid metabolism.
P. Zaphiropoulos, A. Mode, Gunnar Norstedt, Jan-Åke Gustafsson
1989TIPS - Trends in Pharmacological Sciences129 citations
Semantic Scholar
Growth hormone (GH) regulation of cytochrome P-450IIC12, insulin-like growth factor-I (IGF-I), and GH receptor messenger RNA expression in primary rat hepatocytes: a hormonal interplay with insulin, IGF-I, and thyroid hormone.
P. Tollet, Bertil Enberg, A. Mode
1990Molecular Endocrinology121 citations
Semantic Scholar
Down-regulation of cytochrome P450 2C family members and positive acute-phase response gene expression by peroxisome proliferator chemicals.
J. Corton, Li-Qun Fan, Sherri S. Brown, Steven P. Anderson +4 more
1998Molecular Pharmacology114 citations
Semantic Scholar
Sex and the Liver – A Journey Through Five Decades
A. Mode, J. Gustafsson
2006Drug metabolism reviews (Softcover ed.)108 citations
Semantic Scholar
Expression of hepatocyte nuclear factor 6 in rat liver is sex-dependent and regulated by growth hormone.
O. Lahuna, L. Fernández, Hanna L. Karlsson, D. Maiter +4 more
1997Proceedings of the National Academy of Sciences of the United States of America103 citations Open access
Semantic Scholar
Sex change in cytochrome P-450 phenotype by growth hormone treatment of adult rat hepatocytes maintained in a culture system on matrigel.
P. Guzelian, Donna Li, E. Schuetz, Paul E. Thomas +3 more
1988Proceedings of the National Academy of Sciences of the United States of America89 citations Open access
Semantic Scholar
Constitutive expression and hormonal regulation of male sexually differentiated cytochromes P450 in primary cultured rat hepatocytes.
C. Liddle, A. Mode, C. Legraverend, Jan-åke Gustafsson
1992Archives of Biochemistry and Biophysics65 citations
Semantic Scholar
A dual role of growth hormone as a feminizing and masculinizing factor in the control of sex-specific cytochrome P-450 isozymes in rat liver.
A. Mode, E. Wiersma-Larsson, A. Ström, P. Zaphiropoulos +1 more
1989Journal of Endocrinology61 citations
Semantic Scholar
Bile acid synthesis in primary cultures of rat and human hepatocytes
Ewa C. S. Ellis, B. Goodwin, A. Abrahamsson, C. Liddle +4 more
1998Hepatology58 citations Open access
Semantic Scholar
Physiological Differences between Human and Rat Primary Hepatocytes in Response to Liver X Receptor Activation by 3-[3-[N-(2-Chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic Acid Hydrochloride (GW3965)
Pia Kotokorpi, Ewa C. S. Ellis, P. Parini, Lisa-Mari Nilsson +4 more
2007Molecular Pharmacology57 citations
Semantic Scholar
Effects of gender and GH secretory pattern on sterol regulatory element-binding protein-1c and its target genes in rat liver.
C. Améen, D. Lindén, Britt-Mari Larsson, A. Mode +2 more
2004American Journal of Physiology. Endocrinology and Metabolism54 citations
Semantic Scholar
Purification of liver feminizing factor from rat pituitaries and demonstration of its identity with growth hormone.
A. Mode, Gunnar Norstedt, P. Eneroth, Jan-Åke Gustafsson
1983Endocrinology54 citations
Semantic Scholar
A role for protein kinases in the growth hormone regulation of cytochrome P4502C12 and insulin-like growth factor-I messenger RNA expression in primary adult rat hepatocytes.
Petra Toilet, C. Legraverend, Jan-Åke Gustafsson, A. Mode
1991Molecular Endocrinology53 citations Open access
Semantic Scholar
Transcriptional activity and developmental expression of liver X receptor (lxr) in Zebrafish
A. Archer, G. Lauter, G. Hauptmann, A. Mode +1 more
2008Developmental Dynamics50 citations Open access
Semantic Scholar
Desensitization of the Growth Hormone-Induced Janus Kinase 2 (Jak 2)/Signal Transducer and Activator of Transcription 5 (Stat5)-Signaling Pathway Requires Protein Synthesis and Phospholipase C.
L. Fernández, A. Flores-Morales, O. Lahuna, D. Slíva +4 more
1998Endocrinology49 citations
Semantic Scholar
LXR activation by GW3965 alters fat tissue distribution and adipose tissue inflammation in ob/ob female mice[S]
A. Archer, É. Stolarczyk, M. Doria, L. Helguero +5 more
2013Journal of Lipid Research48 citations Open access
Semantic Scholar
Activation of sexual behaviour in castrated rats: the role of oestradiol.
P. Södersten, P. Eneroth, Tiiu Hansson, A. Mode +4 more
1986Journal of Endocrinology45 citations
Semantic Scholar
Induction of prolactin receptors in rat liver after the administration of growth hormone.
Gunnar Norstedt, A. Mode, P. Eneroth, Jan-Åke Gustafsson
1981Endocrinology45 citations
Semantic Scholar
Interaction between growth hormone and insulin in the regulation of lipoprotein metabolism in the rat.
F. Frick, D. Lindén, C. Améen, S. Edén +2 more
2002American Journal of Physiology. Endocrinology and Metabolism44 citations
Semantic Scholar
Transcriptional and posttranscriptional regulation of sexually differentiated rat liver cytochrome P-450 by growth hormone.
A. Mode, E. Wiersma-Larsson, Jan-åke Gustafsson
1989Molecular Endocrinology44 citations Open access
Semantic Scholar
cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15 beta-hydroxylation of steroid sulfates.
P. Zaphiropoulos, A. Mode, A. Ström, Christer Moller +2 more
1988Proceedings of the National Academy of Sciences of the United States of America42 citations Open access
Semantic Scholar
Regulation of sexually dimorphic hepatic steroid metabolism by the somatostatin-growth hormone axis.
Jan-Åke Gustafsson, S. Edén, P. Eneroth, T. Hökfelt +4 more
1983Journal of Steroid Biochemistry42 citations
Semantic Scholar
Effects of gonadal steroid hormones on the hypothalamo-pituitary-liver axis in the control of sex differences in hepatic steroid metabolism in the rat.
A. Mode, Gunnar Norstedt
1982Journal of Endocrinology42 citations
Semantic Scholar
Characterization of the Proximal Promoter and Two Silencer Elements in the CYP2C11 Gene Expressed in Rat Liver
A. Ström, Hidetaka Eguchi, A. Mode, Catherine Legraverend +3 more
1994DNA and Cell Biology41 citations
Semantic Scholar
Growth Hormone Signaling Leading to CYP2C12 Gene Expression in Rat Hepatocytes Involves Phospholipase A2(*)
P. Tollet, M. Hamberg, J. Gustafsson, A. Mode
1995Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Plasma growth hormone pattern and androgens influence the levels of corticosteroid-binding globulin in rat serum.
John-Olov Jansson, Jan Oscarsson, A. Mode, E. Ritzén
1989Journal of Endocrinology39 citations
Semantic Scholar
Transactivation of the rat CYP2C13 gene promoter involves HNF-1, HNF-3, and members of the orphan receptor subfamily.
Catherine Legraverend, Hidetaka Eguchi, A. Ström, Olivier Lahuna +4 more
1994Biochemistry38 citations
Semantic Scholar
Growth hormone regulation of hepatic cytochrome P450 expression in the rat.
A. Mode, P. Tollet, A. Ström, Catherine Legraverend +2 more
1992Advances in Enzyme Regulation38 citations
Semantic Scholar
Cis desensitizes GH induced Stat5 signaling in rat liver cells.
Hanna L. Karlsson, J. Gustafsson, A. Mode
1999Molecular and Cellular Endocrinology37 citations
Semantic Scholar
Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice.
A. Archer, N. Venteclef, A. Mode, M. Pedrelli +5 more
2012Molecular Endocrinology33 citations Open access
Semantic Scholar
CYP2C7 expression in rat liver and hepatocytes: regulation by retinoids.
S. Westin, E. Sonneveld, B. M. van der Leede, P. T. van der Saag +2 more
1997Molecular and Cellular Endocrinology32 citations
Semantic Scholar
CCAAT/enhancer-binding protein-alpha-dependent transactivation of CYP2C12 in rat hepatocytes.
P. Tollet, Olivier Lahuna, R. Ahlgren, A. Mode +1 more
1995Molecular Endocrinology31 citations Open access
Semantic Scholar
Transfection of adult primary rat hepatocytes in culture.
C. Gardmo, Pia Kotokorpi, H. Helander, A. Mode
2005Biochemical Pharmacology30 citations
Semantic Scholar
Pattern-dependent suppression of growth hormone (GH) pulsatility by ghrelin and GH-releasing peptide-6 in moderately GH-deficient rats.
Nichola M. Thompson, J. Davies, A. Mode, P. Houston +1 more
2003Endocrinology30 citations
Semantic Scholar
Hormonal regulation of cytochrome P-450 gene expression.
J. Lund, Peter G. Zaphiropoulos, A. Mode, M. Warner +1 more
1991Advances in Pharmacology30 citations
Semantic Scholar
Effects of hypophysectomy and growth hormone infusion on rat hepatic carbonic anhydrases.
S. Jeffery, C. Wilson, A. Mode, Jan-Åke Gustafsson +1 more
1986Journal of Endocrinology30 citations
Semantic Scholar
Possible role of somatostatin in the regulation of the sexually differentiated steroid metabolism and prolactin receptor in rat liver.
Gunnar Norstedt, A. Mode, T. Hökfelt, P. Eneroth +4 more
1983Endocrinology30 citations Open access
Semantic Scholar
Characterization of orphan nuclear receptor binding elements in sex- differentiated members of the CYP2C gene family expressed in rat liver
A. Strom, S. Westin, H. Eguchi, J. Gustafsson +1 more
1995Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Growth hormone regulation of rat liver gene expression assessed by SSH and microarray.
C. Gardmo, H. Swerdlow, A. Mode
2002Molecular and Cellular Endocrinology26 citations
Semantic Scholar
On the primary site of action of estrogens and androgens in the regulation of hepatic prolactin receptors.
Gunnar Norstedt, A. Mode
1982Endocrinology26 citations
Semantic Scholar
Zonation of cytochrome P450 enzyme expression in rat liver. Isozyme-specific regulation by pituitary dependent hormones.
Teija Oinonen, A. Mode, P. E. Lobie, K. O. Lindros
1996Biochemical Pharmacology24 citations
Semantic Scholar
Growth hormone and vitamin A induce P4502C7 mRNA expression in primary rat hepatocytes.
S. Westin, A. Mode, M. Murray, Ru-Hong Chen +1 more
1993Molecular Pharmacology24 citations
Semantic Scholar
The Human Growth Hormone (hGH) Antagonist G1zoRhGH Does Not Antagonize GH in the Rat, But Has Paradoxical Agonist Activity, Probably Via the Prolactin Receptor*
A. Mode
200123 citations Open access
Semantic Scholar

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S. Westin — researcher profile on SciRah

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O. Isaksson — researcher profile on SciRah