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Hiroko Miyagishi · SciRah

Researcher profile · Semantic Scholar

Hiroko Miyagishi

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Hiroko Miyagishi — researcher profile on SciRah

h-index: 12
Works: 43
Citations: 345

Most-cited papers

Prostaglandin E2-induced cell death is mediated by activation of EP2 receptors in motor neuron-like NSC-34 cells.
Hiroko Miyagishi, Y. Kosuge, Yuki Yoneoka, M. Ozone +5 more
2013Journal of Pharmacological Sciences28 citations Open access
Semantic Scholar
Prostaglandin E2 facilitates neurite outgrowth in a motor neuron-like cell line, NSC-34.
Hiroshi Nango, Y. Kosuge, Hiroko Miyagishi, Kosuke Sugawa +2 more
2017Journal of Pharmacological Sciences27 citations Open access
Semantic Scholar
Protective effect of S-allyl-l-cysteine against endoplasmic reticulum stress-induced neuronal death is mediated by inhibition of calpain
T. Imai, Y. Kosuge, Kaori Endo-Umeda, Hiroko Miyagishi +3 more
2013Amino Acids27 citations
Semantic Scholar
Update on the pathological roles of prostaglandin E2 in neurodegeneration in amyotrophic lateral sclerosis
Hiroshi Nango, Komugi Tsuruta, Hiroko Miyagishi, Y. Aono +2 more
2023Translational Neurodegeneration24 citations Open access
Semantic Scholar
Generation of Cellular Reactive Oxygen Species by Activation of the EP2 Receptor Contributes to Prostaglandin E2-Induced Cytotoxicity in Motor Neuron-Like NSC-34 Cells
Y. Kosuge, Hiroshi Nango, H. Kasai, Takuya Yanagi +5 more
2020Oxidative Medicine and Cellular Longevity23 citations Open access
Semantic Scholar
Increased Expression of 15-Hydroxyprostaglandin Dehydrogenase in Spinal Astrocytes During Disease Progression in a Model of Amyotrophic Lateral Sclerosis
Hiroko Miyagishi, Y. Kosuge, A. Takano, Manami Endo +7 more
2016Cellular and molecular neurobiology20 citations Open access
Semantic Scholar
Neuroprotective effect of yokukansan against cytotoxicity induced by corticosterone on mouse hippocampal neurons.
Y. Nakatani, M. Tsuji, T. Amano, K. Miyagawa +6 more
2014Phytomedicine20 citations
Semantic Scholar
Expression of microsomal prostaglandin E synthase-1 in the spinal cord in a transgenic mouse model of amyotrophic lateral sclerosis.
Hiroko Miyagishi, Y. Kosuge, K. Ishige, Yoshihisa Ito
2012Journal of Pharmacological Sciences20 citations Open access
Semantic Scholar
Protective action of mithramycin against neurodegeneration and impairment of synaptic plasticity in the hippocampal CA1 area after transient global ischemia.
Nobuhiro Osada, Y. Kosuge, S. Oguchi, Hiroko Miyagishi +2 more
2012Neurochemistry International16 citations
Semantic Scholar
Yokukansan, a traditional Japanese herbal medicine, enhances the anxiolytic effect of fluvoxamine and reduces cortical 5-HT2A receptor expression in mice.
Rintaro Ohno, Hiroko Miyagishi, M. Tsuji, Atsumi Saito +3 more
2018Journal of Ethnopharmacology14 citations
Semantic Scholar
Inhibitory effect of yokukansan on the decrease in the hippocampal excitatory amino acid transporter EAAT2 in stress-maladaptive mice
Hiroko Miyagishi, M. Tsuji, Atsumi Saito, K. Miyagawa +1 more
2017Journal of Traditional and Complementary Medicine13 citations Open access
Semantic Scholar
Characterization of Motor Neuron Prostaglandin E2 EP3 Receptor Isoform in a Mouse Model of Amyotrophic Lateral Sclerosis.
Y. Kosuge, Hiroko Miyagishi, T. Shinomiya, K. Nishiyama +6 more
2015Biological and Pharmaceutical Bulletin13 citations Open access
Semantic Scholar
Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
Y. Kosuge, Erina Kaneko, Hiroshi Nango, Hiroko Miyagishi +2 more
2020Oxidative Medicine and Cellular Longevity12 citations Open access
Semantic Scholar
Pathophysiological role of prostaglandin E2‐induced up‐regulation of the EP2 receptor in motor neuron‐like NSC‐34 cells and lumbar motor neurons in ALS model mice
Y. Kosuge, Hiroko Miyagishi, Yuki Yoneoka, K. Yoneda +3 more
2017Neurochemistry International12 citations
Semantic Scholar
The Molecular Mechanisms Underlying Prostaglandin D2-Induced Neuritogenesis in Motor Neuron-Like NSC-34 Cells
Hiroshi Nango, Y. Kosuge, Nana Yoshimura, Hiroko Miyagishi +4 more
2020Cells10 citations Open access
Semantic Scholar
Indirubin derivatives protect against endoplasmic reticulum stress-induced cytotoxicity and down-regulate CHOP levels in HT22 cells.
Y. Kosuge, Hiroaki Saito, Tatsuki Haraguchi, Yoshimi Ichimaru +6 more
2017Bioorganic & Medicinal Chemistry Letters10 citations
Semantic Scholar
Anti-Inflammatory Effects of Miyako Bidens pilosa in a Mouse Model of Amyotrophic Lateral Sclerosis and Lipopolysaccharide-Stimulated BV-2 Microglia
Komugi Tsuruta, Takato Shidara, Hiroko Miyagishi, Hiroshi Nango +5 more
2023International Journal of Molecular Sciences8 citations Open access
Semantic Scholar
Involvement of interleukin‐31 receptor A in morphine‐induced itching and antinociception in mice
M. Tsuji, I. Arai, K. Miyagawa, Hiroko Miyagishi +5 more
2018European Journal of Pain8 citations
Semantic Scholar
Therapeutic Efficacy of Intranasal N-Acetyl-L-Cysteine with Cell-Penetrating Peptide-Modified Polymer Micelles on Neuropathic Pain in Partial Sciatic Nerve Ligation Mice
Hiroshi Nango, Ai Takahashi, Naoto Suzuki, Takumi Kurano +6 more
2025Pharmaceutics7 citations Open access
Semantic Scholar
Relevance of the hippocampal endoplasmic reticulum stress response in a mouse model of chronic kidney disease.
Y. Kosuge, Nobuhiro Osada, Akiko Shimomura, Hiroko Miyagishi +4 more
2018Neuroscience Letters7 citations
Semantic Scholar
Cytoprotective effects of Hangekobokuto against corticosterone-induced cell death in HT22 cells
Hiroko Miyagishi, Ami Joyama, Hiroshi Nango, Koume Nagayama +3 more
2023Journal of Natural Medicines6 citations
Semantic Scholar
Utility of a Novel Micro-Spraying Device for Intranasal Administration of Drug Solutions to Mice
Naoto Suzuki, H. Tanigawa, Taiki Nagatomo, Hiroko Miyagishi +3 more
2023Pharmaceutics5 citations Open access
Semantic Scholar
Characterization of 5-HT1A receptor and transport protein KIF13A expression in the hippocampus of stress-adaptive and -maladaptive mice.
Hiroko Miyagishi, M. Tsuji, K. Miyagawa, K. Kurokawa +4 more
2020Neuroscience Letters4 citations
Semantic Scholar
Possible involvement of monoamine neurons in the emotional abnormality in Kir6.2-deficient mice.
Atsumi Saito, K. Miyagawa, Hiroko Miyagishi, K. Kurokawa +4 more
2018Physiology and Behavior4 citations
Semantic Scholar
Possible role of transcriptional regulation of 5-HT1A receptor in the midbrain on unadaptation to stress in mice.
Hiroko Miyagishi, M. Tsuji, K. Miyagawa, K. Kurokawa +5 more
2022Brain Research3 citations Open access
Semantic Scholar
Pentadecyl®, an odd-chain-rich triglyceride mixture derived from Aurantiochytrium oil, attenuates lipopolysaccharide-induced inflammatory cytokine production in BV-2 microglial cells.
Komugi Tsuruta, Yusei Sato, Hiroshi Nango, Yasuko Sakata +4 more
2025International Immunopharmacology2 citations
Semantic Scholar
Miyako Bidens pilosa Extract Ameliorates Allodynia and Suppresses Spinal Microglial Activation in Mice with Partial Sciatic Nerve Ligation
Ai Takahashi, Hiroko Miyagishi, Komugi Tsuruta, Hiroshi Nango +8 more
2025Current Issues in Molecular Biology1 citations Open access
Semantic Scholar
Renal function-improving action of Pentadecyl®, a multifunctional triglyceride from Aurantiochytrium limacinum, in a mouse model of chronic kidney disease
Keiko Yoneda‑yasui, Hiroshi Nango, Shinpei Fukuhara, Komugi Tsuruta +7 more
2026Experimental and Therapeutic Medicine0 citations Open access
Semantic Scholar
Sustained CREB Phosphorylation Is Associated with Neuritogenic Prostanoid Signaling in NSC-34 Cells
Koume Nagayama, Hiroshi Nango, Komugi Tsuruta, Hiroko Miyagishi +1 more
2026Cells0 citations Open access
Semantic Scholar
Comparative evaluation of amiodarone and furosemide compatibility under different mixing conditions
So Iwabuchi, Toru Imai, Naoto Suzuki, Hiroshi Nango +5 more
2025Scientific Reports0 citations Open access
Semantic Scholar
Miyako Bidens Pilosa extract regulates microglia polarization in a mouse model of amyotrophic lateral sclerosis at advanced-stage
Komugi Tsuruta, Takato Shidara, Ai Takahashi, Hiroko Miyagishi +1 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Possible change in transcriptional regulation of 5-HT1A receptor in the midbrain of stress-maladaptive mice
Hiroko Miyagishi, M. Tsuji, Y. Kosuge, K. Ishige +1 more
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Change in expression of ubiquitin ligase in the hippocampus of stress-maladaptive mice
Hiroko Miyagishi, Y. Kosuge, M. Tsuji, H. Takeda +1 more
2020Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Induction of reactive oxygen species by activation of the EP2 receptor contributes to prostaglandin E2-induced cytotoxicity in motor neuron-like NSC-34 cells
Hiroshi Nango, Y. Kosuge, Hiroko Miyagishi, Yoshihisa Ito +1 more
2020Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Implication of leukemia inhibitory factor in the formation of stress adaptation in mice
K. Kurokawa, M. Tsuji, Hiroko Miyagishi, Atsumi Mochida +3 more
2019Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Genetical and pharmacological inhibition of ATP-sensitive potassium channels induces anxiety-like behavior in mice
Atsumi Mochida, K. Miyagawa, Hidenao Kimijima, Hiroko Miyagishi +5 more
2019Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Ubiquitination of EAAT2 is involved in the impairment of stress adaptation
Hiroko Miyagishi, M. Tsuji, Atsumi Saito, K. Kurokawa +2 more
20180 citations Open access
Semantic Scholar
The role of brain 5-HT7 receptor-ERK system in the formation of stress adaptation in mice
M. Tsuji, Kotaro Takeda, Hiroko Miyagishi, Atsumi Saito +4 more
20180 citations Open access
Semantic Scholar
Prenatal stress induces vulnerability to stress together with the abnormality of central serotonin neurons in mice -Possibility of treatment by Yokukansan-
K. Miyagawa, Atsumi Saito, Hiroko Miyagishi, Kazuhiro Saito +3 more
20180 citations Open access
Semantic Scholar
Possible involvement of histone acetylation in the resistance and adaptation to stress in mice
H. Takeda, K. Miyagawa, Atsumi Saito, Hiroko Miyagishi +4 more
20180 citations Open access
Semantic Scholar
Implication of HCN channels in the frontal cortex on the emotional abnormality of mice induced by exposure to a single restraint stress
K. Kurokawa, K. Miyagawa, Atsumi Saito, Hiroko Miyagishi +2 more
20180 citations Open access
Semantic Scholar
The roles of K ATP channels including Kir6.2 in regulation of emotional behaviors and stress responses
Atsumi Saito, K. Miyagawa, Hiroko Miyagishi, K. Kurokawa +4 more
20180 citations Open access
Semantic Scholar
[Prenatal stress induces vulnerability to stress together with the disruption of central serotonin neurons in mice].
K. Miyagawa, Atsumi Saito, Hiroko Miyagishi, Kotaro Takeda +2 more
2016Nihon yakurigaku zasshi. Folia pharmacologica Japonica0 citations Open access
Semantic Scholar

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Y. Kosuge×21
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Y. Kosuge — researcher profile on SciRah
M. Tsuji×19
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M. Tsuji — researcher profile on SciRah
K. Ishige×18
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K. Ishige — researcher profile on SciRah
H. Takeda×18
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H. Takeda — researcher profile on SciRah

×16

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Hiroshi Nango — researcher profile on SciRah

K. Miyagawa×16

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K. Miyagawa — researcher profile on SciRah

Yoshihisa Ito×13

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Yoshihisa Ito — researcher profile on SciRah

Atsumi Saito×12

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Atsumi Saito — researcher profile on SciRah

K. Kurokawa×12

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K. Kurokawa — researcher profile on SciRah

Komugi Tsuruta×7

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Komugi Tsuruta — researcher profile on SciRah

Nobuhiro Osada×4

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Nobuhiro Osada — researcher profile on SciRah

Kotaro Takeda×4

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Kotaro Takeda — researcher profile on SciRah