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K. Sobue · SciRah

Researcher profile · Semantic Scholar

K. Sobue

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K. Sobue — researcher profile on SciRah

h-index: 52
Works: 178
Citations: 11K

Most-cited papers

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
R. Malik, G. Chauhan, M. Traylor, M. Sargurupremraj +273 more
2018Nature Genetics1,441 citations Open access
Semantic Scholar
The Tohoku Medical Megabank Project: Design and Mission
Shinichi Kuriyama, Nobuo Yaegashi, F. Nagami, Tomohiko Arai +54 more
2016Journal of Epidemiology319 citations Open access
Semantic Scholar
Dual roles of myocardin-related transcription factors in epithelial–mesenchymal transition via slug induction and actin remodeling
Tsuyoshi Morita, T. Mayanagi, K. Sobue
2007Journal of Cell Biology279 citations Open access
Semantic Scholar
Expressional regulation of smooth muscle cell-specific genes in association with phenotypic modulation
K. Sobue, Ken’ichiro Hayashi, W. Nishida
2004Molecular and Cellular Biochemistry236 citations
Semantic Scholar
Phenotypic Modulation of Vascular Smooth Muscle Cells Induced by Unsaturated Lysophosphatidic Acids
Ken’ichiro Hayashi, Masanori Takahashi, W. Nishida, K. Yoshida +5 more
2001Circulation Research208 citations Open access
Semantic Scholar
Differential Control of Postsynaptic Density Scaffolds via Actin-Dependent and -Independent Mechanisms
T. Kuriu, A. Inoue, H. Bito, K. Sobue +1 more
2006Journal of Neuroscience203 citations Open access
Semantic Scholar
Changes in the Balance of Phosphoinositide 3-Kinase/Protein Kinase B (Akt) and the Mitogen-activated Protein Kinases (ERK/p38MAPK) Determine a Phenotype of Visceral and Vascular Smooth Muscle Cells
K. Hayashi, Masanori Takahashi, K. Kimura, W. Nishida +2 more
1999Journal of Cell Biology195 citations Open access
Semantic Scholar
Differentiated Phenotype of Smooth Muscle Cells Depends on Signaling Pathways through Insulin-like Growth Factors and Phosphatidylinositol 3-Kinase*
Ken’ichiro Hayashi, H. Saga, Y. Chimori, K. Kimura +2 more
1998Journal of Biological Chemistry188 citations Open access
Semantic Scholar
Determination of absolute protein numbers in single synapses by a GFP-based calibration technique
Yoshiko Sugiyama, Izumi Kawabata, K. Sobue, S. Okabe
2005Nature Methods180 citations
Semantic Scholar
Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway*
Tsuyoshi Morita, K. Sobue
2009Journal of Biological Chemistry132 citations Open access
Semantic Scholar
Rapid Redistribution of the Postsynaptic Density Protein PSD-Zip45 (Homer 1c) and Its Differential Regulation by NMDA Receptors and Calcium Channels
S. Okabe, T. Urushido, D. Konno, H. Okado +1 more
2001Journal of Neuroscience130 citations Open access
Semantic Scholar
A Triad of Serum Response Factor and the GATA and NK Families Governs the Transcription of Smooth and Cardiac Muscle Genes*
W. Nishida, Mako Nakamura, S. Mori, Masanori Takahashi +6 more
2002Journal of Biological Chemistry126 citations Open access
Semantic Scholar
Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study
A. Hozawa, K. Tanno, N. Nakaya, Tomohiro Nakamura +79 more
2020Journal of Epidemiology119 citations Open access
Semantic Scholar
Vascular Remodeling Induced by Naturally Occurring Unsaturated Lysophosphatidic Acid In Vivo
K. Yoshida, W. Nishida, Ken’ichiro Hayashi, Y. Ohkawa +4 more
2003Circulation109 citations
Semantic Scholar
Reciprocal expression of MRTF‐A and myocardin is crucial for pathological vascular remodelling in mice
Takeya Minami, K. Kuwahara, Y. Nakagawa, M. Takaoka +18 more
2012EMBO Journal102 citations Open access
Semantic Scholar
Detrimental effects of glucocorticoids on neuronal migration during brain development
K. Fukumoto, T. Morita, T. Mayanagi, D. Tanokashira +3 more
2009Molecular Psychiatry98 citations Open access
Semantic Scholar
Bone Morphogenetic Protein-Induced Msx1 and Msx2 Inhibit Myocardin-Dependent Smooth Muscle Gene Transcription
Ken’ichiro Hayashi, Seiji Nakamura, W. Nishida, K. Sobue
2006Molecular and Cellular Biology90 citations Open access
Semantic Scholar
Diversification of caldesmon-linked actin cytoskeleton in cell motility
T. Mayanagi, K. Sobue
2011Cell Adhesion & Migration87 citations Open access
Semantic Scholar
Involvement of the Phosphatidylinositol 3-Kinase/Rac1 and Cdc42 Pathways in Radial Migration of Cortical Neurons*
D. Konno, Saori Yoshimura, Kei Hori, Hisato Maruoka +1 more
2005Journal of Biological Chemistry82 citations Open access
Semantic Scholar
Synchronized Formation and Remodeling of Postsynaptic Densities: Long-Term Visualization of Hippocampal Neurons Expressing Postsynaptic Density Proteins Tagged with Green Fluorescent Protein
T. Ebihara, Izumi Kawabata, Shinichi Usui, K. Sobue +1 more
2003Journal of Neuroscience81 citations Open access
Semantic Scholar
Modulation of the Channel Activity of the ε2/ζ1-Subtype N-Methyl d-Aspartate Receptor by PSD-95*
Yasue Yamada, Yasuyo Chochi, K. Takamiya, K. Sobue +1 more
1999Journal of Biological Chemistry80 citations Open access
Semantic Scholar
Reorganization of the actin cytoskeleton via transcriptional regulation of cytoskeletal/focal adhesion genes by myocardin-related transcription factors (MRTFs/MAL/MKLs).
Tsuyoshi Morita, T. Mayanagi, K. Sobue
2007Experimental Cell Research74 citations
Semantic Scholar
Epiregulin as a Major Autocrine/Paracrine Factor Released From ERK- and p38MAPK-Activated Vascular Smooth Muscle Cells
Masanori Takahashi, Ken’ichiro Hayashi, K. Yoshida, Y. Ohkawa +7 more
2003Circulation74 citations Open access
Semantic Scholar
Insulin Receptor Substrate-1/SHP-2 Interaction, a Phenotype-dependent Switching Machinery of Insulin-like Growth Factor-I Signaling in Vascular Smooth Muscle Cells*
Ken’ichiro Hayashi, K. Shibata, Tsuyoshi Morita, K. Iwasaki +2 more
2004Journal of Biological Chemistry72 citations Open access
Semantic Scholar
Kupffer cell-mediated down regulation of rat hepatic CMOAT/MRP2 gene expression.
J. Nakamura, T. Nishida, Ken’ichiro Hayashi, N. Kawada +5 more
1999Biochemical and Biophysical Research Communications - BBRC69 citations
Semantic Scholar
iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation
S. Komaki, Yuh Shiwa, Ryohei Furukawa, T. Hachiya +7 more
2018Human Genome Variation64 citations Open access
Semantic Scholar
Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies
T. Hachiya, Ryohei Furukawa, Yuh Shiwa, H. Ohmomo +17 more
2017npj Genomic Medicine63 citations Open access
Semantic Scholar
Rho/Rho-associated Kinase Signal Regulates Myogenic Differentiation via Myocardin-related Transcription Factor-A/Smad-dependent Transcription of the Id3 Gene*
K. Iwasaki, Ken’ichiro Hayashi, T. Fujioka, K. Sobue
2008Journal of Biological Chemistry61 citations Open access
Semantic Scholar
Glucocorticoid Receptor-mediated Expression of Caldesmon Regulates Cell Migration via the Reorganization of the Actin Cytoskeleton*
T. Mayanagi, Tsuyoshi Morita, Ken’ichiro Hayashi, K. Fukumoto +1 more
2008Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Changes in the Balance between Caldesmon Regulated by p21-activated Kinases and the Arp2/3 Complex Govern Podosome Formation*
Tsuyoshi Morita, T. Mayanagi, Toshiyuki Yoshio, K. Sobue
2007Journal of Biological Chemistry56 citations Open access
Semantic Scholar
ProSAP-interacting Protein 1 (ProSAPiP1), a Novel Protein of the Postsynaptic Density That Links the Spine-associated Rap-Gap (SPAR) to the Scaffolding Protein ProSAP2/Shank3*
D. Wendholt, C. Spilker, A. Schmitt, A. Dolnik +7 more
2006Journal of Biological Chemistry56 citations Open access
Semantic Scholar
NMDA Receptor-Dependent Synaptic Translocation of Insulin Receptor Substrate p53 via Protein Kinase C Signaling
Kei Hori, H. Yasuda, D. Konno, Hisato Maruoka +2 more
2005Journal of Neuroscience56 citations Open access
Semantic Scholar
Genetic Predisposition to Ischemic Stroke A Polygenic Risk Score
T. Hachiya, Y. Kamatani, A. Takahashi, J. Hata +37 more
201752 citations
Semantic Scholar
Nuclear Import Mechanism for Myocardin Family Members and Their Correlation with Vascular Smooth Muscle Cell Phenotype*
Seiji Nakamura, Ken’ichiro Hayashi, K. Iwasaki, T. Fujioka +3 more
2010Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Molecular Mechanism of Phenotypic Modulation of Smooth Muscle Cells
K. Sobue, Ken'ichiro Hayashi, W. Nishida
1998Hormone Research in Paediatrics51 citations
Semantic Scholar
Genetic Predisposition to Ischemic Stroke
T. Hachiya, Y. Kamatani, A. Takahashi, J. Hata +37 more
2017Stroke49 citations Open access
Semantic Scholar
Isolation of PSD‐Zip45, a novel Homer/vesl family protein containing leucine zipper motifs, from rat brain 1
Jie Sun, Satoko Tadokoro, T. Imanaka, Seiko D. Murakami +5 more
1998FEBS Letters49 citations
Semantic Scholar
Serum magnesium and calcium levels in relation to ischemic stroke
S. Larsson, M. Traylor, S. Burgess, G. Boncoraglio +255 more
2019Neurology46 citations Open access
Semantic Scholar
Expression profiles of nestin in vascular smooth muscle cells in vivo and in vitro.
H. Oikawa, Ken’ichiro Hayashi, C. Maesawa, T. Masuda +1 more
2010Experimental Cell Research46 citations
Semantic Scholar
Synaptic Targeting of PSD-Zip45 (Homer 1c) and Its Involvement in the Synaptic Accumulation of F-actin*
Shinichi Usui, D. Konno, Kei Hori, Hisato Maruoka +4 more
2003Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Differential modulation of NR1‐NR2A and NR1‐NR2B subtypes of NMDA receptor by PDZ domain‐containing proteins
Takashi Iwamoto, Yasue Yamada, Kei Hori, Yoshifumi Watanabe +2 more
2004Journal of Neurochemistry44 citations
Semantic Scholar
Crystal structure of the Homer 1 family conserved region reveals the interaction between the EVH1 domain and own proline-rich motif.
Katsumasa Irie, T. Nakatsu, K. Mitsuoka, A. Miyazawa +5 more
2002Journal of Molecular Biology39 citations
Semantic Scholar
Myocardin functions as an effective inducer of growth arrest and differentiation in human uterine leiomyosarcoma cells.
Y. Kimura, Tsuyoshi Morita, Ken’ichiro Hayashi, T. Miki +1 more
2010Cancer Research36 citations Open access
Semantic Scholar
MALS is a binding partner of IRSp53 at cell–cell contacts
Kei Hori, D. Konno, Hisato Maruoka, K. Sobue
2003FEBS Letters35 citations Open access
Semantic Scholar
Glucocorticoid Suppresses Dendritic Spine Development Mediated by Down-Regulation of Caldesmon Expression
Daisuke Tanokashira, Tsuyoshi Morita, Ken’ichiro Hayashi, T. Mayanagi +4 more
2012Journal of Neuroscience33 citations Open access
Semantic Scholar
Calcineurin-mediated pathway involved in the differentiated phenotype of smooth muscle cells.
Y. Ohkawa, Ken’ichiro Hayashi, K. Sobue
2003Biochemical and Biophysical Research Communications - BBRC32 citations
Semantic Scholar
The postsynaptic density and dendritic raft localization of PSD-Zip70, which contains an N-myristoylation sequence and leucine-zipper motifs
D. Konno, Ji-Ae Ko, Shinichi Usui, Kei Hori +7 more
2002Journal of Cell Science31 citations Open access
Semantic Scholar
Collaboration of PSD-Zip70 with Its Binding Partner, SPAR, in Dendritic Spine Maturity
Hisato Maruoka, D. Konno, Kei Hori, K. Sobue
2005Journal of Neuroscience29 citations Open access
Semantic Scholar
Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols
Yuh Shiwa, T. Hachiya, Ryohei Furukawa, H. Ohmomo +19 more
2016PLoS ONE28 citations Open access
Semantic Scholar
Docosahexaenoic Acid Promotes Axon Outgrowth by Translational Regulation of Tau and Collapsin Response Mediator Protein 2 Expression*
Toshinari Mita, T. Mayanagi, Hiroshi Ichijo, K. Fukumoto +3 more
2016Journal of Biological Chemistry27 citations Open access
Semantic Scholar

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