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T. Perls · SciRah

Researcher profile · Semantic Scholar

T. Perls

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T. Perls — researcher profile on SciRah

h-index: 58
Works: 259
Citations: 13K

Most-cited papers

A catalog of genetic loci associated with kidney function from analyses of a million individuals
M. Wuttke, Yong Li, Man Li, Karsten B. Sieber +324 more
2019Nature Genetics767 citations Open access
Semantic Scholar
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
M. Feitosa, A. Kraja, D. Chasman, Yun J. Sung +269 more
2018PLoS ONE764 citations Open access
Semantic Scholar
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
A. Tin, J. Marten, Victoria L. Halperin Kuhns, Yong Li +222 more
2019Nature Genetics365 citations Open access
Semantic Scholar
A meta-analysis of genome-wide association studies identifies multiple longevity genes
J. Deelen, D. Evans, D. Arking, N. Tesi +80 more
2019Nature Communications335 citations Open access
Semantic Scholar
APOE Alleles and Extreme Human Longevity
P. Sebastiani, A. Gurinovich, M. Nygaard, T. Sasaki +12 more
2018The journals of gerontology. Series A, Biological sciences and medical sciences136 citations Open access
Semantic Scholar
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.
A. Kraja, Chun-Yu Liu, J. Fetterman, M. Graff +148 more
2019American Journal of Human Genetics110 citations Open access
Semantic Scholar
Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans
P. Sebastiani, Anthony Federico, M. Morris, A. Gurinovich +10 more
2021Aging Cell86 citations Open access
Semantic Scholar
COVID‐19 Deaths in Long‐Term Care Facilities: A Critical Piece of the Pandemic Puzzle
Rossana Lau-Ng, Lisa Caruso, T. Perls
2020Journal of The American Geriatrics Society75 citations Open access
Semantic Scholar
Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevity
Tanya T. Karagiannis, Todd W. Dowrey, C. Villacorta-Martin, Monty Montano +7 more
2022bioRxiv72 citations Open access
Semantic Scholar
NIA Long Life Family Study: Objectives, Design, and Heritability of Cross-Sectional and Longitudinal Phenotypes
M. Wojczynski, S. Lin, P. Sebastiani, T. Perls +6 more
2021The journals of gerontology. Series A, Biological sciences and medical sciences54 citations Open access
Semantic Scholar
Metabolite signatures of chronological age, aging, survival, and longevity
Paola Sebastiani, Stefano Monti, Michael S. Lustgarten, Ze-Yuan Song +28 more
2024Cell Reports52 citations Open access
Semantic Scholar
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Yun J. Sung, L. de las Fuentes, T. Winkler, D. Chasman +277 more
2019Human Molecular Genetics39 citations Open access
Semantic Scholar
A serum protein signature of APOE genotypes in centenarians
P. Sebastiani, S. Monti, M. Morris, A. Gurinovich +7 more
2019Aging Cell30 citations Open access
Semantic Scholar
Association of Fatigue, Inflammation, and Physical Activity on Gait Speed: The Long Life Family Study
Sharon W Renner, Y. Qiao, T. Gmelin, A. Santanasto +6 more
2021Aging Clinical and Experimental Research29 citations Open access
Semantic Scholar
Patterns of multi-domain cognitive aging in participants of the Long Life Family Study
P. Sebastiani, S. Andersen, B. Sweigart, Meng-Tian Du +5 more
2020GeroScience26 citations Open access
Semantic Scholar
Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study
A. Yashin, K. Arbeev, Deqing Wu, L. Arbeeva +15 more
2018The journals of gerontology. Series A, Biological sciences and medical sciences25 citations Open access
Semantic Scholar
Reduced Prevalence and Incidence of Cognitive Impairment Among Centenarian Offspring
S. Andersen, B. Sweigart, P. Sebastiani, J. Drury +2 more
2018The journals of gerontology. Series A, Biological sciences and medical sciences23 citations Open access
Semantic Scholar
Digitally generated Trail Making Test data: Analysis using hidden Markov modeling
Meng-Tian Du, S. Andersen, S. Cosentino, R. Boudreau +2 more
2022Alzheimer's & Dementia22 citations Open access
Semantic Scholar
Effect of longevity genetic variants on the molecular aging rate
A. Gurinovich, Ze-Yuan Song, William B. Zhang, Anthony Federico +8 more
2021GeroScience22 citations Open access
Semantic Scholar
APOE E2/E2 Is Associated With Slower Rate Of Cognitive Decline With Age
B. Sweigart, S. Andersen, A. Gurinovich, S. Cosentino +3 more
2021Journal of Alzheimer's Disease22 citations Open access
Semantic Scholar
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
L. de las Fuentes, Yun J. Sung, R. Noordam, T. Winkler +218 more
2020Molecular Psychiatry22 citations Open access
Semantic Scholar
Genetic Associations with Age of Menopause in Familial Longevity
H. Bae, K. Lunetta, J. Murabito, S. Andersen +3 more
2019Menopause19 citations Open access
Semantic Scholar
A metabolomic signature of the APOE2 allele
Paola Sebastiani, Ze-Yuan Song, Dylan Ellis, Qu Tian +26 more
2022GeroScience18 citations Open access
Semantic Scholar
A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants
H. Bae, A. Gurinovich, Tanya T. Karagiannis, Ze-Yuan Song +18 more
2022International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Heterogeneity of healthy aging: comparing long-lived families across five healthy aging phenotypes of blood pressure, memory, pulmonary function, grip strength, and metabolism
M. Marron, M. Wojczynski, R. Minster, R. Boudreau +11 more
2019GeroScience16 citations Open access
Semantic Scholar
Distribution of 54 polygenic risk scores for common diseases in long lived individuals and their offspring
Sophia Gunn, Michael Wainberg, Ze-Yuan Song, S. Andersen +10 more
2021GeroScience15 citations Open access
Semantic Scholar
Evaluation of GENESIS, SAIGE, REGENIE and fastGWA-GLMM for genome-wide association studies of binary traits in correlated data
A. Gurinovich, Meng Li, Anastasia Leshchyk, H. Bae +6 more
2022Frontiers in Genetics14 citations Open access
Semantic Scholar
Digital Technology Differentiates Graphomotor and Information Processing Speed Patterns of Behavior
S. Andersen, B. Sweigart, N. Glynn, M. Wojczynski +8 more
2021Journal of Alzheimer's Disease14 citations Open access
Semantic Scholar
Whole genome‐wide sequence analysis of long‐lived families (Long‐Life Family Study) identifies MTUS2 gene associated with late‐onset Alzheimer's disease
L. Xicota, S. Cosentino, B. Vardarajan, R. Mayeux +14 more
2024Alzheimer's & Dementia13 citations Open access
Semantic Scholar
Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies
M. Feitosa, K. Lunetta, Li-Hua Wang, M. Wojczynski +6 more
2020Atherosclerosis13 citations Open access
Semantic Scholar
Studying the Interplay Between Apolipoprotein E and Education on Cognitive Decline in Centenarians Using Bayesian Beta Regression
Qing-Yan Xiang, S. Andersen, T. Perls, Paola Sebastiani
2020Frontiers in Genetics12 citations Open access
Semantic Scholar
A longevity‐specific bank of induced pluripotent stem cells from centenarians and their offspring
Todd W. Dowrey, Samuel F. Cranston, Nicholas J. Skvir, Yvonne Lok +13 more
2024Aging Cell8 citations Open access
Semantic Scholar
Cross-platform proteomics signatures of extreme old age
Eric R. Reed, K. B. Chandler, Prisma Lopez, Catherine E. Costello +7 more
2024GeroScience8 citations Open access
Semantic Scholar
Slower decline in processing speed is associated with familial longevity
S. Andersen, Meng-Tian Du, S. Cosentino, N. Schupf +3 more
2021Gerontology8 citations Open access
Semantic Scholar
Cognitive Trajectories and Resilience in Centenarians-Findings From the 100-Plus Study.
T. Perls
2021JAMA Network Open8 citations Open access
Semantic Scholar
Association between APOE alleles and Change of Neuropsychological Tests in the Long Life Family Study
Meng-Tian Du, S. Andersen, N. Schupf, M. Feitosa +3 more
2020Journal of Alzheimer's Disease8 citations Open access
Semantic Scholar
Mosaic chromosomal alterations and human longevity.
Anastasia Leshchyk, Qing-Yan Xiang, S. Andersen, A. Gurinovich +9 more
2023The journals of gerontology. Series A, Biological sciences and medical sciences7 citations Open access
Semantic Scholar
Association between late maternal age and age-related endophenotypes in the Long Life Family Study
S. Barral, S. Andersen, T. Perls, H. Bae +5 more
2022Neuroscience Letters7 citations Open access
Semantic Scholar
PopCluster: an algorithm to identify genetic variants with ethnicity-dependent effects
A. Gurinovich, H. Bae, J. Farrell, S. Andersen +6 more
2019Bioinform.7 citations Open access
Semantic Scholar
Signatures of neuropsychological test results in the Long Life Family Study: A cluster analysis
Qing-Yan Xiang, S. Andersen, B. Sweigart, Sophia Gunn +3 more
2023Journal of Alzheimer's Disease6 citations Open access
Semantic Scholar
Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes
J. Deelen, D. Evans, D. Arking, N. Tesi +80 more
2021Nature Communications6 citations Open access
Semantic Scholar
Heterogeneity of the Predictive Polygenic Risk Scores for Coronary Heart Disease Age-at-Onset in Three Different Coronary Heart Disease Family-Based Ascertainments
M. Feitosa, Allison L. Kuipers, M. Wojczynski, Li-Hua Wang +9 more
2021Circulation Genomic and Precision Medicine6 citations Open access
Semantic Scholar
The relationship between 11 different polygenic longevity scores, parental lifespan, and disease diagnosis in the UK Biobank
Janith Don, A. Schork, Gwênlyn Glusman, N. Rappaport +11 more
2024GeroScience5 citations Open access
Semantic Scholar
Rare Genetic Variants Correlate with Better Processing Speed
Ze-Yuan Song, A. Gurinovich, M. Nygaard, J. Mengel-From +10 more
2022bioRxiv5 citations Open access
Semantic Scholar
Successful aging and its subtypes in Centenarians: The Chinese Experience
T. Perls
2023Journal of The American Geriatrics Society4 citations Open access
Semantic Scholar
Healthy Longevity: An Introduction to the Special Issue.
T. Perls, E. Tan
2019The journals of gerontology. Series A, Biological sciences and medical sciences4 citations Open access
Semantic Scholar
A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E
Paola Sebastiani, Eric R. Reed, K. B. Chandler, Prisma Lopez +17 more
2025Advancement of science2 citations Open access
Semantic Scholar
Cross-platform proteomics signatures of extreme old age
Eric R. Reed, K. B. Chandler, Prisma Lopez, Catherine E. Costello +7 more
2024bioRxiv2 citations Open access
Semantic Scholar
Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci
L. de las Fuentes, K. Schwander, Michael R. Brown, Amy R. Bentley +194 more
2023Frontiers in Genetics2 citations Open access
Semantic Scholar
SNP rs6543176 is associated with extreme human longevity but increased risk for cancer
A. Gurinovich, Ze-Yuan Song, H. Bae, Anastasia Leshchyk +10 more
2025GeroScience1 citations Open access
Semantic Scholar

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