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K. Mantwill · SciRah

Researcher profile · Semantic Scholar

K. Mantwill

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K. Mantwill — researcher profile on SciRah

h-index: 17
Works: 32
Citations: 823

Most-cited papers

YB-1 Relocates to the Nucleus in Adenovirus-infected Cells and Facilitates Viral Replication by Inducing E2 Gene Expression through the E2 Late Promoter*
P. Holm, S. Bergmann, Karsten Jürchott, H. Lage +8 more
2002Journal of Biological Chemistry108 citations Open access
Semantic Scholar
Concepts in Oncolytic Adenovirus Therapy
K. Mantwill, Florian G Klein, Dongbiao Wang, Sruthi V Hindupur +3 more
2021International Journal of Molecular Sciences87 citations Open access
Semantic Scholar
Identification of differentially expressed genes in human melanoma cells with acquired resistance to various antineoplastic drugs
C. Grottke, K. Mantwill, M. Dietel, D. Schadendorf +1 more
2000International Journal of Cancer69 citations
Semantic Scholar
Inhibition of the multidrug-resistant phenotype by targeting YB-1 with a conditionally oncolytic adenovirus: implications for combinatorial treatment regimen with chemotherapeutic agents.
K. Mantwill, Nadia Köhler-Vargas, Alexandra Bernshausen, Alexa Bieler +8 more
2006Cancer Research62 citations Open access
Semantic Scholar
Multidrug-resistant Cancer Cells Facilitate E1-independent Adenoviral Replication
P. Holm, H. Lage, S. Bergmann, Karsten Jürchott +10 more
2004Cancer Research60 citations Open access
Semantic Scholar
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells
K. Mantwill, U. Naumann, Janina Seznec, V. Girbinger +6 more
2013Journal of Translational Medicine57 citations Open access
Semantic Scholar
Novel Three-Pronged Strategy to Enhance Cancer Cell Killing in Glioblastoma Cell Lines: Histone Deacetylase Inhibitor, Chemotherapy, and Oncolytic Adenovirus dl520
Alexa Bieler, K. Mantwill, Tanja Dravits, Alexandra Bernshausen +5 more
2005Human Gene Therapy49 citations
Semantic Scholar
Impact of radiation therapy on the oncolytic adenovirus dl520: implications on the treatment of glioblastoma.
Alexa Bieler, K. Mantwill, R. Holzmüller, Karsten Jürchott +7 more
2008Radiotherapy and Oncology45 citations
Semantic Scholar
Expression of Y-box-binding protein YB-1 allows stratification into long- and short-term survivors of head and neck cancer patients
A. Kolk, N. Jubitz, K. Mengele, K. Mantwill +4 more
2011British Journal of Cancer43 citations Open access
Semantic Scholar
YB‐1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma
R. Holzmüller, K. Mantwill, Cornelia Haczek, E. Rognoni +9 more
2011International Journal of Cancer40 citations Open access
Semantic Scholar
Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo
E. Rognoni, M. Widmaier, Cornelia Haczek, K. Mantwill +9 more
2009Cancer Gene Therapy32 citations Open access
Semantic Scholar
Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus
J. Koch, S. J. Schober, Sruthi V Hindupur, Caroline Schöning +11 more
2022Nature Communications30 citations Open access
Semantic Scholar
The Oncolytic Adenovirus XVir-N-31 as a Novel Therapy in Muscle-Invasive Bladder Cancer
E. Lichtenegger, Florestan J. Koll, H. Haas, K. Mantwill +8 more
2019Human Gene Therapy25 citations
Semantic Scholar
Characterization of the Recombinant Adenovirus Vector AdYB-1: Implications for Oncolytic Vector Development
G. Glockzin, K. Mantwill, Karsten Jürchott, Alexandra Bernshausen +4 more
2006Journal of Virology21 citations Open access
Semantic Scholar
The oncolytic adenovirus XVir-N-31 joins forces with CDK4/6 inhibition augmenting innate and adaptive antitumor immunity in Ewing sarcoma.
S. J. Schober, C. Schoening, Jennifer Eck, Charlotte Middendorf +13 more
2023Clinical Cancer Research20 citations Open access
Semantic Scholar
An armed, YB-1-dependent oncolytic adenovirus as a candidate for a combinatorial anti-glioma approach of virotherapy, suicide gene therapy and chemotherapeutic treatment
Y. Kostova, K. Mantwill, P. Holm, M. Anton
2014Cancer Gene Therapy20 citations Open access
Semantic Scholar
The Oncolytic Adenovirus XVir-N-31, in Combination with the Blockade of the PD-1/PD-L1 Axis, Conveys Abscopal Effects in a Humanized Glioblastoma Mouse Model
Moritz Klawitter, Ali El-Ayoubi, Jasmin Buch, Jakob Rüttinger +8 more
2022International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Adenovirus Particle Quantification in Cell Lysates Using Light Scattering
A. Hohl, A. S. Ramms, C. Dohmen, K. Mantwill +5 more
2017Human Gene Therapy Methods13 citations
Semantic Scholar
Targeting Cell Cycle Facilitates E1A-Independent Adenoviral Replication
M. Ehrenfeld, Felicia Segeth, K. Mantwill, C. Brockhaus +6 more
2023Journal of Virology8 citations
Semantic Scholar
Oncolytic virotherapy provides a potent therapy option for squamous bladder cancer
Julia Pannhausen, J. Wirtz, K. Mantwill, P. Holm +6 more
2025Scientific Reports5 citations Open access
Semantic Scholar
Identification of the KIF and MCM protein families as novel targets for combination therapy with CDK4/6 inhibitors in bladder cancer.
Julian Kositza, Julia Nguyen, Ting Hong, K. Mantwill +1 more
2023Urologic oncology5 citations
Semantic Scholar
Characterization of a MAb to ovarian cancer and its possible diagnostic application.
A. Salmassi, L. Mettler, H. Wolf, K. Mantwill +2 more
1999European Journal of Gynaecological Oncology3 citations
Semantic Scholar
CDK4/6 inhibitors improve therapy of oncolytic adenovirus by manipulation of RB-E2F regulated transcription
R. Nawroth, Jana Koch, K. Mantwill, S. Hindupuhr +2 more
20201 citations
Semantic Scholar
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells
K. Mantwill, U. Naumann, Janina Seznec, V. Girbinger +6 more
2013Journal of Translational Medicine1 citations Open access
Semantic Scholar
Integration of a multimeric STAT consensus site into the adenoviral genome to interfere with IFN signaling represents a novel concept to improve oncolytic virotherapy
Dongbiao Wang, Sonja Nassua, K. Mantwill, Yuling Zhao +4 more
2026Journal of Virology0 citations Open access
Semantic Scholar
Identification of a Conserved Temporal Molecular Response Signature to CDK4/6 Inhibition Through Multi-Omics Integration Across Cancer Cell Lines
Anna C. Hogger, Ting Hong, K. Mantwill, N. Gaisa +2 more
2026International Journal of Molecular Sciences0 citations Open access
Semantic Scholar
Genome-Wide CRISPR Screening for the Identification of Therapy Resistance-Associated Genes in Urothelial Carcinoma.
K. Mantwill, R. Nawroth
2023Methods in molecular biology0 citations
Semantic Scholar
32 Treatment of bladder cancer with YB-1 dependent oncolytic adenovirus: Preliminary in vitro studies
Florestan J. Koll, K. Mantwill, S. Schmid, G. Multhoff +3 more
20150 citations
Semantic Scholar
438: Effects of a New Oncolytic Adenovirus (XVIR03) in Human Prostate Cancer Cell Lines and in Xenograft Mouse Model
U. Treiber, K. Mantwill, Nadia Köhler-Vargas, Alexandra Bernshausen +6 more
20060 citations
Semantic Scholar
EFFECTS OF A NEW ONCOLYTIC ADENOVIRUS (XVIR03) IN HUMAN PROSTATE CANCER CELL LINES AND IN XENOGRAFT MOUSE MODEL
U. Treiber, K. Mantwill, N. Vargas, Alexandra Bernshausen +6 more
20060 citations
Semantic Scholar
532. Effects of a New YB-1 Dependent Adenovirus (XVir) in Human Prostate Cancer Cell Lines and in a Xenograft Mouse Model|[ast]|
K. Mantwill, Nadia Koehler-Vargas, Alexandra Bernshausen, U. Treiber +3 more
20050 citations Open access
Semantic Scholar
440. The Multidrug Resistant Phenotype in Tumor Cells Facilitates Adenoviral Replication: New Concepts for Oncolytic Vector Development
Alexandra Bernshausen, G. Glockzin, K. Mantwill, H. Royer +3 more
20040 citations Open access
Semantic Scholar

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