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P. Mesirca · SciRah

Researcher profile · Semantic Scholar

P. Mesirca

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P. Mesirca — researcher profile on SciRah

h-index: 30
Works: 118
Citations: 2,391

Most-cited papers

Functional role of voltage gated Ca2+ channels in heart automaticity
P. Mesirca, A. Torrente, M. Mangoni
2015Frontiers in Physiology133 citations Open access
Semantic Scholar
Control of heart rate by cAMP sensitivity of HCN channels
J. Alig, L. Marger, P. Mesirca, H. Ehmke +2 more
2009Proceedings of the National Academy of Sciences of the United States of America124 citations Open access
Semantic Scholar
Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity
R. Sah, P. Mesirca, Marjolein Van den Boogert, Jonathan N. Rosen +3 more
2013Proceedings of the National Academy of Sciences of the United States of America115 citations Open access
Semantic Scholar
The Timing of Myocardial Trpm7 Deletion during Cardiogenesis Variably Disrupts Adult Ventricular Function, Conduction and Repolarization
R. Sah, P. Mesirca, Xenos Mason, William J. Gibson +6 more
2013Circulation109 citations Open access
Semantic Scholar
L-type Cav1.3 channels regulate ryanodine receptor-dependent Ca2+ release during sino-atrial node pacemaker activity.
A. Torrente, P. Mesirca, P. Ñeco, R. Rizzetto +8 more
2016Cardiovascular Research104 citations Open access
Semantic Scholar
Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.
L. Marger, P. Mesirca, J. Alig, A. Torrente +10 more
2011Channels86 citations Open access
Semantic Scholar
Paradoxical Effect of Increased Diastolic Ca2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia
P. Ñeco, A. Torrente, P. Mesirca, E. Zorio +7 more
2012Circulation83 citations Open access
Semantic Scholar
Cardiac arrhythmia induced by genetic silencing of “funny” (f) channels is rescued by GIRK4 inactivation
P. Mesirca, J. Alig, A. Torrente, J. Müller +17 more
2014Nature Communications80 citations Open access
Semantic Scholar
The G-protein–gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation
P. Mesirca, L. Marger, F. Toyoda, R. Rizzetto +11 more
2013The Journal of General Physiology79 citations Open access
Semantic Scholar
Distinct localization and modulation of Cav1.2 and Cav1.3 L‐type Ca2+ channels in mouse sinoatrial node
Carl J. Christel, Natalia Cardona, P. Mesirca, Stefan Herrmann +5 more
2012Journal of Physiology70 citations Open access
Semantic Scholar
A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate
A. D'Souza, Yanwen Wang, Cali Anderson, A. Bucchi +26 more
2020Heart Rhythm68 citations Open access
Semantic Scholar
G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block
P. Mesirca, I. Bidaud, F. Briec, S. Evain +11 more
2016Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
T-type channels in the sino-atrial and atrioventricular pacemaker mechanism
P. Mesirca, A. Torrente, M. Mangoni
2014Pflügers Archiv: European Journal of Physiology57 citations
Semantic Scholar
Pacemaker activity and ionic currents in mouse atrioventricular node cells
L. Marger, P. Mesirca, J. Alig, A. Torrente +10 more
2011Channels56 citations Open access
Semantic Scholar
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels
A. Saponaro, F. Cantini, A. Porro, A. Bucchi +10 more
2018eLife51 citations Open access
Semantic Scholar
Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells.
G. Del Vecchio, A. Giuliani, Mercedes Fernández, P. Mesirca +6 more
2009Neuroscience Letters49 citations
Semantic Scholar
Pharmacologic Approach to Sinoatrial Node Dysfunction
P. Mesirca, V. Fedorov, T. Hund, A. Torrente +3 more
2020Annual Review of Pharmacology and Toxicology46 citations Open access
Semantic Scholar
Concomitant genetic ablation of L-type Cav1.3 (α1D) and T-type Cav3.1 (α1G) Ca2+ channels disrupts heart automaticity
M. Baudot, E. Torre, I. Bidaud, J. Louradour +7 more
2020Scientific Reports45 citations Open access
Semantic Scholar
Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes
P. Mesirca, S. Nakao, S. Nissen, G. Forte +21 more
2021Circulation Research38 citations Open access
Semantic Scholar
CaV1.3 L-type Ca2+ channel contributes to the heartbeat by generating a dihydropyridine-sensitive persistent Na+ current
F. Toyoda, P. Mesirca, S. Dubel, Wei-Guang Ding +3 more
2017Scientific Reports38 citations Open access
Semantic Scholar
Genetic Complexity of Sinoatrial Node Dysfunction
Michael J. Wallace, Mona El Refaey, P. Mesirca, T. Hund +2 more
2021Frontiers in Genetics37 citations Open access
Semantic Scholar
L-Type Cav1.3 Calcium Channels Are Required for Beta-Adrenergic Triggered Automaticity in Dormant Mouse Sinoatrial Pacemaker Cells
J. Louradour, Olivier Bortolotti, E. Torre, I. Bidaud +5 more
2022Cells32 citations Open access
Semantic Scholar
RyR2R420Q catecholaminergic polymorphic ventricular tachycardia mutation induces bradycardia by disturbing the coupled clock pacemaker mechanism.
Yue-Yi Wang, P. Mesirca, Elena Marqués-Sulé, A. Zahradníková +8 more
2017JCI Insight30 citations Open access
Semantic Scholar
Channelopathies of voltage-gated L-type Cav1.3/α1D and T-type Cav3.1/α1G Ca2+ channels in dysfunction of heart automaticity
A. Torrente, P. Mesirca, I. Bidaud, M. Mangoni
2020Pflügers Archiv: European Journal of Physiology24 citations Open access
Semantic Scholar
Rescuing cardiac automaticity in L‐type Cav1.3 channelopathies and beyond
P. Mesirca, I. Bidaud, M. Mangoni
2016Journal of Physiology24 citations Open access
Semantic Scholar
Selective blockade of Cav1.2 (α1C) versus Cav1.3 (α1D) L-type calcium channels by the black mamba toxin calciseptine
P. Mesirca, J. Chemin, C. Barrère, Eleonora Torre +9 more
2024Nature Communications22 citations Open access
Semantic Scholar
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease.
M. Boyett, J. Yanni, James O. Tellez, A. Bucchi +22 more
2021Progress in Biophysics and Molecular Biology22 citations Open access
Semantic Scholar
Functional roles of Cav1.3, Cav3.1 and HCN channels in automaticity of mouse atrioventricular cells
L. Marger, P. Mesirca, J. Alig, A. Torrente +10 more
201122 citations Open access
Semantic Scholar
Genetic Ablation of G Protein-Gated Inwardly Rectifying K+ Channels Prevents Training-Induced Sinus Bradycardia
I. Bidaud, A. D'Souza, G. Forte, E. Torre +10 more
2021Frontiers in Physiology19 citations Open access
Semantic Scholar
Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity
Daniel G. P. Turner, Chen Kang, P. Mesirca, Juan Hong +3 more
2021Frontiers in Cardiovascular Medicine18 citations Open access
Semantic Scholar
Weak Static and Extremely Low Frequency Magnetic Fields Affect In Vitro Pollen Germination
L. Betti, Grazia Trebbi, Fabio Fregola, M. Zurla +3 more
2011TheScientificWorldJournal18 citations Open access
Semantic Scholar
Clock-dependent and system-driven oscillators interact in the suprachiasmatic nuclei to pace mammalian circadian rhythms
Karine Abitbol, S. Debiesse, François Molino, P. Mesirca +6 more
2017PLoS ONE17 citations Open access
Semantic Scholar
Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia
I. Bidaud, Antony Chung You Chong, Agnès Carcouet, S. De Waard +8 more
2020Scientific Reports13 citations Open access
Semantic Scholar
Cav1.3 L-Type Calcium Channels-Mediated Ryanodine Receptor Dependent Calcium Release Controls Heart Rate
A. Torrente, P. Mesirca, P. Ñeco, Martina Sinegger-Brauns +5 more
201113 citations Open access
Semantic Scholar
Cardiac GR Mediates the Diurnal Rhythm in Ventricular Arrhythmia Susceptibility
R. Tikhomirov, R. H. Oakley, Cali Anderson, Yirong Xiang +18 more
2024Circulation Research11 citations Open access
Semantic Scholar
Symptomatic bradyarrhythmias in the athlete - underlying mechanisms and treatments.
S. Al-Othman, M. Boyett, Gwilym M. Morris, A. Malhotra +3 more
2024Heart Rhythm11 citations Open access
Semantic Scholar
The funny current in genetically modified mice.
M. L. DiFrancesco, P. Mesirca, I. Bidaud, D. Isbrandt +1 more
2021Progress in Biophysics and Molecular Biology8 citations Open access
Semantic Scholar
Computational modelling of mouse atrio ventricular node action potential and automaticity
C. Bartolucci, P. Mesirca, E. Ricci, Clara Sales-Bellés +4 more
2024Journal of Physiology7 citations Open access
Semantic Scholar
Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node
Niroj Shrestha, K. Zorn-Pauly, P. Mesirca, C. N. Koyani +14 more
2023Proceedings of the National Academy of Sciences of the United States of America7 citations Open access
Semantic Scholar
State-of-the-Art Differentiation Protocols for Patient-Derived Cardiac Pacemaker Cells
Eleonora Torre, Matteo E. Mangoni, A. Lacampagne, A. Meli +1 more
2024International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Maurocalcin and its analogue MCaE12A facilitate Ca2+ mobilization in cardiomyocytes.
S. De Waard, J. Montnach, C. Cortinovis, O. Chkir +9 more
2020Biochemical Journal4 citations Open access
Semantic Scholar
Evidence for a selective blockade of Cav1.2 versus Cav1.3 by the mamba toxin calciseptine in the mouse heart
C. Barrère, K. Chinda, P. Mesirca, C. Aurelie +5 more
20204 citations Open access
Semantic Scholar
Pacemaker Cells of the Atrioventricular Node are CaV1.3 Dependent Oscillators
P. Mesirca, L. Marger, A. Torrente, J. Striessnig +2 more
20104 citations Open access
Semantic Scholar
Characterization of sinoatrial automaticity in Microcebus murinus to study the effect of aging on cardiac activity and the correlation with longevity
M. L. DiFrancesco, Manon Marrot, E. Torre, P. Mesirca +10 more
2023Scientific Reports3 citations Open access
Semantic Scholar
Nfix: a transcription factor with an important functional role in cardiac automaticity
P. Mesirca
2023Acta Physiologica3 citations Open access
Semantic Scholar
Heart rate reduction after genetic ablation of L-type Cav1.3 channels induces cardioprotection against ischemia-reperfusion injury
V. Delgado-Betancourt, K. Chinda, P. Mesirca, C. Barrère +10 more
2023Frontiers in Cardiovascular Medicine2 citations Open access
Semantic Scholar
Hypercalcemia impairs sino-atrial automaticity through excessive Cav1.2-mediated Ca2+ influx
A. Torrente, L. Fossier, M. Baudot, I. Bidaud +2 more
20202 citations Open access
Semantic Scholar
Bradycardic mice undergo effective heart rate improvement after specific homing to the sino-atrial node and differentiation of adult muscle derived stem cells
P. Mesirca, D. Mamaeva, I. Bidaud, Matthias Baudot +11 more
2018bioRxiv2 citations Open access
Semantic Scholar
Heart Block in the Athlete - Role of Ion Channel Remodelling as Studied Using a One-dimensional Computational Model of the Atrioventricular Node
Jue Li, A. D'Souza, Yanwen Wang, S. Nakao +5 more
2018International Conference on Computing in Cardiology2 citations Open access
Semantic Scholar
Editorial: Cardiac Pacemaking in Health and Disease: From Genes to Function
A. D'Souza, G. J. Boink, F. Toyoda, P. Mesirca
2022Frontiers in Physiology1 citations Open access
Semantic Scholar

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M. Mangoni — researcher profile on SciRah
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I. Bidaud×17
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