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R. S. Lahue · SciRah

Researcher profile · Semantic Scholar

R. S. Lahue

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R. S. Lahue — researcher profile on SciRah

h-index: 31
Works: 65
Citations: 5,213

Most-cited papers

Mismatch repair in replication fidelity, genetic recombination, and cancer biology.
P. Modrich, R. S. Lahue
1996Annual Review of Biochemistry1,591 citations
Semantic Scholar
DNA mismatch correction in a defined system.
R. S. Lahue, Karin G. Au, P. Modrich
1989Science562 citations
Semantic Scholar
Mispair specificity of methyl-directed DNA mismatch correction in vitro.
S. Su, R. S. Lahue, Karin G. Au, P. Modrich
1988Journal of Biological Chemistry312 citations Open access
Semantic Scholar
Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae.
E. Selva, L. New, G. Crouse, R. S. Lahue
1995Genetics214 citations Open access
Semantic Scholar
Methyl-directed mismatch repair is bidirectional.
D. Cooper, R. S. Lahue, P. Modrich
1993Journal of Biological Chemistry207 citations Open access
Semantic Scholar
Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae.
Juan J. Miret, L. Pessoa-Brandão, R. S. Lahue
1998Proceedings of the National Academy of Sciences of the United States of America184 citations Open access
Semantic Scholar
Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats.
Craig Spiro, Richard Pelletier, Michael L. Rolfsmeier, Michael J. Dixon +6 more
1999Molecules and Cells179 citations Open access
Semantic Scholar
Replication and Expansion of Trinucleotide Repeats in Yeast
Richard Pelletier, M. Krasilnikova, G. Samadashwily, R. S. Lahue +1 more
2003Molecular and Cellular Biology166 citations Open access
Semantic Scholar
Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition
Eric Alani, Tanya Sokolsky, B. Studamire, Juan J. Miret +1 more
1997Molecular and Cellular Biology142 citations Open access
Semantic Scholar
Requirement for d(GATC) sequences in Escherichia coli mutHLS mismatch correction.
R. S. Lahue, S. Su, P. Modrich
1987Proceedings of the National Academy of Sciences of the United States of America102 citations Open access
Semantic Scholar
Instability of CAG and CTG trinucleotide repeats in Saccharomyces cerevisiae
Juan J. Miret, Luis Pessoa-Brandão, R. S. Lahue
1997Molecular and Cellular Biology93 citations Open access
Semantic Scholar
Saccharomyces cerevisiae Srs2 DNA Helicase Selectively Blocks Expansions of Trinucleotide Repeats
Saumitri Bhattacharyya, R. S. Lahue
2004Molecular and Cellular Biology83 citations Open access
Semantic Scholar
Stabilizing Effects of Interruptions on Trinucleotide Repeat Expansions in Saccharomyces cerevisiae
M. Rolfsmeier, R. S. Lahue
2000Molecular and Cellular Biology77 citations Open access
Semantic Scholar
MutSβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells
A. Gannon, Aisling Frizzell, Evan Healy, R. S. Lahue
2012Nucleic Acids Research70 citations Open access
Semantic Scholar
A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington’s disease mice
N. Suelves, L. Kirkham-McCarthy, R. S. Lahue, S. Ginés
2017Scientific Reports68 citations Open access
Semantic Scholar
Histone Deacetylase Complexes Promote Trinucleotide Repeat Expansions
Kim Debacker, Aisling Frizzell, Olive Gleeson, L. Kirkham-McCarthy +2 more
2012PLoS Biology67 citations Open access
Semantic Scholar
DNA repair and trinucleotide repeat instability.
R. S. Lahue, Dan Slater
2003Frontiers in Bioscience61 citations Open access
Semantic Scholar
Cis-elements governing trinucleotide repeat instability in Saccharomyces cerevisiae.
Michael L. Rolfsmeier, Michael J. Dixon, Luis Pessoa-Brandão, Richard Pelletier +2 more
2001Genetics61 citations
Semantic Scholar
Postreplication Repair Inhibits CAG · CTG Repeat Expansions in Saccharomyces cerevisiae
Danielle L. Daee, Tony M. Mertz, R. S. Lahue
2006Molecular and Cellular Biology59 citations Open access
Semantic Scholar
New Functions of Ctf18-RFC in Preserving Genome Stability outside Its Role in Sister Chromatid Cohesion
L. Gellon, David F. Razidlo, Olive Gleeson, Lauren Verra +3 more
2011PLoS Genetics50 citations Open access
Semantic Scholar
Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms.
David F. Razidlo, R. S. Lahue
2008DNA Repair48 citations Open access
Semantic Scholar
Mismatch repair blocks expansions of interrupted trinucleotide repeats in yeast.
Michael L. Rolfsmeier, Michael J. Dixon, R. S. Lahue
2000Molecules and Cells47 citations Open access
Semantic Scholar
MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions
N. Keogh, Kara Y. Chan, Guo-Min Li, R. S. Lahue
2017Nucleic Acids Research43 citations Open access
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Expansions of CAG.CTG repeats in immortalized human astrocytes.
David A. Claassen, R. S. Lahue
2007Human Molecular Genetics41 citations Open access
Semantic Scholar
RTEL1 Inhibits Trinucleotide Repeat Expansions and Fragility
Aisling Frizzell, J. Nguyen, Mark I. R. Petalcorin, Katherine D. Turner +3 more
2014Cell Reports38 citations Open access
Semantic Scholar
Srs2 Helicase of Saccharomyces cerevisiae Selectively Unwinds Triplet Repeat DNA*
Saumitri Bhattacharyya, R. S. Lahue
2005Journal of Biological Chemistry35 citations Open access
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Histone deacetylase complexes as caretakers of genome stability
R. S. Lahue, Aisling Frizzell
2012Epigenetics34 citations Open access
Semantic Scholar
Efficient repair of large DNA loops in Saccharomyces cerevisiae.
Stephanie E. Corrette-Bennett, Natasha L. Mohlman, Z. Rosado, J. Miret +3 more
2001Nucleic Acids Research34 citations Open access
Semantic Scholar
Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae
Alok Dhar, R. S. Lahue
2008Nucleic Acids Research33 citations Open access
Semantic Scholar
Characterization of a DNA mismatch-binding activity in yeast extracts.
Juan J. Miret, M. Milla, R. S. Lahue
1993Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Mechanistic features of CAG•CTG repeat contractions in cultured cells revealed by a novel genetic assay
Richard Pelletier, B. Farrell, J. Miret, R. S. Lahue
2005Nucleic Acids Research32 citations Open access
Semantic Scholar
Differential effects of the mismatch repair genes MSH2 and MSH3 on homeologous recombination in Saccharomyces cerevisiae
Erica M. Selva, Alan Baer Maderazo, R. S. Lahue
1997Molecular and General Genetics MGG31 citations
Semantic Scholar
Correction of Large Mispaired DNA Loops by Extracts ofSaccharomyces cerevisiae *
Stephanie E. Corrette-Bennett, B. Parker, Natasha L. Mohlman, R. S. Lahue
1999Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Identification of RTG2 as a modifier gene for CTG*CAG repeat instability in Saccharomyces cerevisiae.
Saumitri Bhattacharyya, M. Rolfsmeier, M. Dixon, K. Wagoner +1 more
2002Genetics27 citations
Semantic Scholar
Methyl-directed DNA mismatch repair in Escherichia coli.
R. S. Lahue, Paul Modrich
1988Mutation research27 citations
Semantic Scholar
Rev1 enhances CAG.CTG repeat stability in Saccharomyces cerevisiae.
Natasha S Collins, Saumitri Bhattacharyya, R. S. Lahue
2007DNA Repair25 citations
Semantic Scholar
HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions
Gregory M. Williams, Vasileios S. Paschalis, Janice Ortega, F. Muskett +4 more
2020Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
CAG·CTG repeat instability in cultured human astrocytes
B. Farrell, R. S. Lahue
2006Nucleic Acids Research24 citations Open access
Semantic Scholar
Examining the potential role of DNA polymerases η and ζ in triplet repeat instability in yeast
M. Dixon, R. S. Lahue
200222 citations
Semantic Scholar
Recognition of DNA insertion/deletion mismatches by an activity in Saccharomyces cerevisiae.
Juan J. Miret, B. Parker, R. S. Lahue
1996Nucleic Acids Research22 citations Open access
Semantic Scholar
Genetic assays for triplet repeat instability in yeast.
M. Dixon, Saumitri Bhattacharyya, R. S. Lahue
2004Methods in molecular biology21 citations
Semantic Scholar
New developments in Huntington’s disease and other triplet repeat diseases: DNA repair turns to the dark side
R. S. Lahue
2020Neuronal Signaling20 citations Open access
Semantic Scholar
Trinucleotide repeat expansions catalyzed by human cell-free extracts
J. R. Stevens, E. Lahue, Guo-Min Li, R. S. Lahue
2013Cell Research19 citations Open access
Semantic Scholar
DNA polymerase delta, RFC and PCNA are required for repair synthesis of large looped heteroduplexes in Saccharomyces cerevisiae.
Stephanie E. Corrette-Bennett, C. D. Borgeson, D. Sommer, P. Burgers +1 more
2004Nucleic Acids Research19 citations Open access
Semantic Scholar
Terbium luminescence as a probe of the calcium binding site of trypsin and α-chymotrypsin
J. de Jersey, R. S. Lahue, R.Bruce Martin
198017 citations
Semantic Scholar
Anc1, a Protein Associated with Multiple Transcription Complexes, Is Involved in Postreplication Repair Pathway in S. cerevisiae
R. Erlich, R. Fry, Thomas J. Begley, Danielle L. Daee +2 more
2008PLoS ONE16 citations Open access
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Nucleotide excision repair and the 26S proteasome function together to promote trinucleotide repeat expansions.
C. Concannon, R. S. Lahue
2014DNA Repair14 citations
Semantic Scholar
Mismatch repair assay.
Stephanie E. Corrette-Bennett, R. S. Lahue
1999Methods in molecular biology14 citations
Semantic Scholar
DNA elements important for CAG*CTG repeat thresholds in Saccharomyces cerevisiae.
M. Dixon, R. S. Lahue
2004Nucleic Acids Research13 citations Open access
Semantic Scholar
The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination.
Yan-Fang Ye, L. Kirkham-McCarthy, R. S. Lahue
2016DNA Repair11 citations
Semantic Scholar

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Juan J. Miret×6
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Juan J. Miret — researcher profile on SciRah
P. Modrich×5
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Saumitri Bhattacharyya×5
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Richard Pelletier×4
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Aisling Frizzell

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Stephanie E. Corrette-Bennett×4

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