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C. V. van Drunen · SciRah

Researcher profile · Semantic Scholar

C. V. van Drunen

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C. V. van Drunen — researcher profile on SciRah

h-index: 43
Works: 137
Citations: 8,891

Most-cited papers

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
J. Mjösberg, S. Trifari, N. Crellin, C. Peters +5 more
2011Nature Immunology1,151 citations Open access
Semantic Scholar
Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers.
P. Tomassen, G. Vandeplas, T. van Zele, L. Cardell +18 more
2016Journal of Allergy and Clinical Immunology1,057 citations Open access
Semantic Scholar
Chronic rhinosinusitis in Europe – an underestimated disease. A GA2LEN study
D. Hastan, W. Fokkens, C. Bachert, R. Newson +22 more
2011Allergy. European Journal of Allergy and Clinical Immunology1,042 citations
Semantic Scholar
The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells.
J. Mjösberg, J. Bernink, K. Golebski, J. Karrich +6 more
2012Immunity630 citations Open access
Semantic Scholar
IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs
S. Bal, J. Bernink, M. Nagasawa, Jelle Groot +13 more
2016Nature Immunology458 citations Open access
Semantic Scholar
Viruses and bacteria in acute asthma exacerbations – A GA2LEN‐DARE* systematic review
N. G. Papadopoulos, Ioannis Christodoulou, G. Rohde, I. Agache +41 more
2010Allergy. European Journal of Allergy and Clinical Immunology302 citations Open access
Semantic Scholar
Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response.
K. Golebski, J. Layhadi, U. Sahiner, E. Steveling-Klein +18 more
2021Immunity224 citations Open access
Semantic Scholar
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages
Willianne Hoepel, Hung-Jen Chen, C. Geyer, Sona Allahverdiyeva +32 more
2021Science Translational Medicine223 citations Open access
Semantic Scholar
The Global Allergy and Asthma European Network (GALEN rhinosinusitis cohort: a large European cross-sectional study of chronic rhinosinusitis patients with and without nasal polyps.
Asif H Khan, G. Vandeplas, T. Huynh, Vijay N. Joish +20 more
2019Rhinology156 citations Open access
Semantic Scholar
Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.
R. Molenaar, D. Botman, M. A. Smits, V. Hira +16 more
2015Cancer Research131 citations
Semantic Scholar
IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation
K. Golebski, X. R. Ros, M. Nagasawa, S. van Tol +10 more
2019Nature Communications127 citations Open access
Semantic Scholar
Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases
E. K. van der Ploeg, K. Golebski, M. van Nimwegen, J. Fergusson +18 more
2021Science immunology113 citations Open access
Semantic Scholar
IL-17-high asthma with features of a psoriasis immunophenotype.
J. Östling, M. van Geest, J. Schofield, Z. Jevnikar +279 more
2019Journal of Allergy and Clinical Immunology103 citations Open access
Semantic Scholar
Nasal hyper‐reactivity is a common feature in both allergic and nonallergic rhinitis
C. Segboer, C. Holland, S. Reinartz, I. Terreehorst +4 more
2013Allergy. European Journal of Allergy and Clinical Immunology82 citations
Semantic Scholar
The effect of topical amphotericin B on inflammatory markers in patients with chronic rhinosinusitis: A multicenter randomized controlled study
F. Ebbens, C. Georgalas, S. Luiten, C. V. van Drunen +10 more
2009The Laryngoscope77 citations
Semantic Scholar
Stratification of asthma phenotypes by airway proteomic signatures.
J. Schofield, D. Burg, B. Nicholas, Fabio Strazzeri +129 more
2019Journal of Allergy and Clinical Immunology75 citations Open access
Semantic Scholar
Acute and chronic rhinosinusitis and allergic rhinitis in relation to comorbidity, ethnicity and environment
R. Hoffmans, A. Wagemakers, C. V. van Drunen, P. Hellings +1 more
2018PLoS ONE72 citations Open access
Semantic Scholar
Aerodynamic effects of inferior turbinate surgery on nasal airflow - a computational fluid dynamics model*
S. Bobic, C. V. van Drunen, I. Callebaut, V. Hox +3 more
201066 citations
Semantic Scholar
Molecular Mechanisms of Nasal Epithelium in Rhinitis and Rhinosinusitis
S. Toppila-Salmi, C. V. van Drunen, W. Fokkens, K. Golebski +4 more
2014Current Allergy and Asthma Reports54 citations Open access
Semantic Scholar
Executive summary of European Task Force document on diagnostic tools in rhinology.
P. Hellings, G. Scadding, I. Alobid, C. Bachert +10 more
2012Rhinology54 citations Open access
Semantic Scholar
Fungus: a role in pathophysiology of chronic rhinosinusitis, disease modifier, a treatment target, or no role at all?
W. Fokkens, F. Ebbens, C. V. van Drunen
2009Immunology and allergy clinics of North America51 citations
Semantic Scholar
The association of asthma, nasal allergies, and positive skin prick tests with obesity, leptin, and adiponectin
R. Newson, M. Jones, B. Forsberg, C. Janson +15 more
2014Clinical and Experimental Allergy49 citations Open access
Semantic Scholar
Role of fungi in pathogenesis of chronic rhinosinusitis: the hypothesis rejected
W. Fokkens, C. V. van Drunen, C. Georgalas, F. Ebbens
2012Current Opinion in Otolaryngology & Head and Neck Surgery49 citations
Semantic Scholar
Capsaicin for non-allergic rhinitis.
A. Gevorgyan, C. Segboer, R. Gorissen, C. V. van Drunen +1 more
2015Cochrane Database of Systematic Reviews48 citations Open access
Semantic Scholar
Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia
G. Amatngalim, L. Rodenburg, B. Aalbers, H. Raeven +17 more
2022Life Science Alliance47 citations Open access
Semantic Scholar
The multi‐faceted role of allergen exposure to the local airway mucosa
Korneliusz Golebski, Kil Roschmann, S. Toppila-Salmi, H. Hammad +4 more
2013Allergy. European Journal of Allergy and Clinical Immunology47 citations Open access
Semantic Scholar
Inflammation in chronic rhinosinusitis and nasal polyposis.
C. V. van Drunen, S. Reinartz, Jochem Wigman, W. Fokkens
2009Immunology and allergy clinics of North America44 citations
Semantic Scholar
The Impact of Allergic Rhinitis and Asthma on Human Nasal and Bronchial Epithelial Gene Expression
A. Wagener, A. Zwinderman, S. Luiten, W. Fokkens +3 more
2013PLoS ONE43 citations Open access
Semantic Scholar
Quality of life is significantly impaired in nonallergic rhinitis patients
C. Segboer, Ingrid Terreehorst, A. Gevorgyan, P. Hellings +2 more
2018Allergy. European Journal of Allergy and Clinical Immunology41 citations Open access
Semantic Scholar
Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD
G. V. Van Pottelberge, K. Bracke, Sarah Van den Broeck, S. Reinartz +6 more
2010European Respiratory Journal39 citations Open access
Semantic Scholar
High Degree of Overlap between Responses to a Virus and to the House Dust Mite Allergen in Airway Epithelial Cells
K. Golebski, S. Luiten, D. van Egmond, E. D. de Groot +3 more
2014PLoS ONE38 citations Open access
Semantic Scholar
UvA-DARE ( Digital Academic Repository ) Recalcitrant chronic rhinosinusitis . Difficulties in diagnosis and treatment
C. Georgalas, D. Menger, C. V. van Drunen
201137 citations
Semantic Scholar
Specific Induction of TSLP by the Viral RNA Analogue Poly(I:C) in Primary Epithelial Cells Derived from Nasal Polyps
K. Golebski, J. van Tongeren, D. van Egmond, E. D. de Groot +2 more
2016PLoS ONE36 citations Open access
Semantic Scholar
Endothelial L‐selectin ligand expression in nasal polyps
F. Ebbens, S. Toppila-Salmi, J. Renkonen, R. Renkonen +3 more
2010Allergy. European Journal of Allergy and Clinical Immunology36 citations
Semantic Scholar
Is chronic rhinosinusitis related to allergic rhinitis in adults and children? Applying epidemiological guidelines for causation.
C. Georgalas, Ioannis Vlastos, V. Picavet, C. V. van Drunen +2 more
2014Allergy. European Journal of Allergy and Clinical Immunology35 citations Open access
Semantic Scholar
Role of Innate Immunity in the Pathogenesis of Chronic Rhinosinusitis: Progress and New Avenues
C. V. van Drunen, J. Mjösberg, C. Segboer, M. Cornet +1 more
2012Current Allergy and Asthma Reports35 citations Open access
Semantic Scholar
Timothy grass pollen extract‐induced gene expression and signalling pathways in airway epithelial cells
K. Röschmann, Silvia Luiten, M. Jonker, Timo M. Breit +3 more
2011Clinical and Experimental Allergy34 citations
Semantic Scholar
FcγRIII stimulation breaks the tolerance of human nasal epithelial cells to bacteria through cross-talk with TLR4
K. Golebski, Willianne Hoepel, D. van Egmond, E. D. de Groot +5 more
2019Mucosal Immunology29 citations Open access
Semantic Scholar
Expression profiling and functional analysis of Toll-like receptors in primary healthy human nasal epithelial cells shows no correlation and a refractory LPS response
J. van Tongeren, K. Röschmann, S. Reinartz, S. Luiten +3 more
2015Clinical and Translational Allergy29 citations Open access
Semantic Scholar
Endotyping of non-allergic, allergic and mixed rhinitis patients using a broad panel of biomarkers in nasal secretions
C. Segboer, W. Fokkens, I. Terreehorst, C. V. van Drunen
2018PLoS ONE28 citations Open access
Semantic Scholar
dsRNA-induced changes in gene expression profiles of primary nasal and bronchial epithelial cells from patients with asthma, rhinitis and controls
A. Wagener, A. Zwinderman, S. Luiten, W. Fokkens +3 more
2014Respiratory Research28 citations Open access
Semantic Scholar
Inhibition of capsaicin-driven nasal hyper-reactivity by SB-705498, a TRPV1 antagonist.
C. Holland, C. V. van Drunen, J. Denyer, K. Smart +6 more
2014British Journal of Clinical Pharmacology28 citations Open access
Semantic Scholar
Histone deacetylase inhibitors up-regulate LL-37 expression independent of toll-like receptor mediated signalling in airway epithelial cells
Quan Liu, Juan Liu, K. I. L. Roschmann, D. van Egmond +4 more
2013Journal of Inflammation25 citations Open access
Semantic Scholar
Childhood asthma in the new omics era: challenges and perspectives
Korneliusz Golebski, M. Kabesch, E. Mélen, U. Potočnik +4 more
2019Current Opinion in Allergy and Clinical Immunology23 citations Open access
Semantic Scholar
Biologicals in childhood severe asthma: the European PERMEABLE survey on the status quo
Elisangela Santos-Valente, H. Buntrock-Döpke, Rola Abou Taam, S. Arasi +43 more
2021ERJ Open Research19 citations Open access
Semantic Scholar
EGR-1 and DUSP-1 are important negative regulators of pro-allergic responses in airway epithelium.
K. Golebski, D. van Egmond, E. D. de Groot, K. I. L. Roschmann +2 more
2015Molecular Immunology19 citations
Semantic Scholar
A chest physician's guide to mechanisms of sinonasal disease
V. Hox, T. Maes, W. Huvenne, C. V. van Drunen +7 more
2015Thorax19 citations Open access
Semantic Scholar
Dendritic cells in nasal mucosa of subjects with different allergic sensitizations.
S. Reinartz, J. van Tongeren, D. van Egmond, E. D. de Groot +2 more
2011Journal of Allergy and Clinical Immunology19 citations Open access
Semantic Scholar
Predictors of post-operative response to treatment: a double blind placebo controlled study in chronic rhinosinusitis patients.
F. Ebbens, S. Toppila-Salmi, E. D. de Groot, J. Renkonen +4 more
2011Rhinology18 citations Open access
Semantic Scholar
Dexamethasone-induced apoptosis of freshly isolated human nasal epithelial cells concomitant with abrogation of IL-8 production.
S. Bobic, C. V. van Drunen, I. Callebaut, V. Hox +3 more
2010Rhinology18 citations Open access
Semantic Scholar

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