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A. Castor · SciRah

Researcher profile · Semantic Scholar

A. Castor

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A. Castor — researcher profile on SciRah

h-index: 20
Works: 78
Citations: 2,356

Most-cited papers

Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia
A. Castor, L. Nilsson, Ing-Britt Åstrand-Grundström, M. Buitenhuis +12 more
2005Nature Medicine366 citations
Semantic Scholar
Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study
A. Biondi, M. Schrappe, P. de Lorenzo, A. Castor +12 more
2012The Lancet Oncology320 citations Open access
Semantic Scholar
Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
H. Lilljebjörn, Rasmus Henningsson, Axel Hyrenius-Wittsten, L. Olsson +15 more
2016Nature Communications268 citations Open access
Semantic Scholar
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia
K. Paulsson, H. Lilljebjörn, Andrea Biloglav, L. Olsson +8 more
2015Nature Genetics181 citations
Semantic Scholar
High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle.
A. Tipping, Cristina Pina, A. Castor, D. Hong +5 more
2009Blood126 citations
Semantic Scholar
Pharmacokinetics of doxorubicin in children with acute lymphoblastic leukemia: multi-institutional collaborative study.
B. Frost, S. Eksborg, O. Bjork, J. Abrahamsson +4 more
2002Medical and Pediatric Oncology98 citations
Semantic Scholar
Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor a
G. Cazzaniga, P. de Lorenzo, J. Alten, S. Röttgers +21 more
2017Haematologica97 citations Open access
Semantic Scholar
Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial.
A. Biondi, V. Gandemer, P. de Lorenzo, G. Cario +16 more
2018The Lancet Haematology95 citations Open access
Semantic Scholar
Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis.
M. Buitenhuis, L. Verhagen, H. V. van Deutekom, A. Castor +4 more
2008Blood82 citations Open access
Semantic Scholar
Differential regulation of granulopoiesis by the basic helix-loop-helix transcriptional inhibitors Id1 and Id2.
M. Buitenhuis, H. V. van Deutekom, L. Verhagen, A. Castor +4 more
2005Blood81 citations
Semantic Scholar
Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia
Minjun Yang, Mattias Vesterlund, Ioannis Siavelis, L. Moura-Castro +11 more
2019Nature Communications75 citations Open access
Semantic Scholar
Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011
L. Olsson, A. Castor, M. Behrendtz, Andrea Biloglav +3 more
2014Leukemia73 citations
Semantic Scholar
Vincristine in childhood leukaemia: no pharmacokinetic rationale for dose reduction in adolescents
B. Frost, G. Lönnerholm, P. Koopmans, J. Abrahamsson +5 more
2003Acta paediatrica55 citations
Semantic Scholar
Quiescent Leukaemic Cells Account for Minimal Residual Disease in Childhood Lymphoblastic Leukaemia
Christopher T. Lutz, Petter S. Woll, Georgina Hall, A. Castor +12 more
2012Leukemia45 citations Open access
Semantic Scholar
Vincristine pharmacokinetics is related to clinical outcome in children with standard risk acute lymphoblastic leukemia
G. Lönnerholm, B. Frost, J. Abrahamsson, M. Behrendtz +5 more
2008British Journal of Haematology36 citations
Semantic Scholar
Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2A
K. Karrman, A. Castor, M. Behrendtz, E. Forestier +6 more
2015Journal of Hematology & Oncology35 citations Open access
Semantic Scholar
Support from healthcare services during transition to adulthood - Experiences of young adult survivors of pediatric cancer.
P. Svedberg, Eva-Lena Einberg, Pontus Wärnestål, J. Stigmar +3 more
2016European Journal of Oncology Nursing30 citations
Semantic Scholar
Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor
A. Biondi, G. Cario, P. de Lorenzo, A. Castor +14 more
2018Haematologica28 citations Open access
Semantic Scholar
Cooperative genetic changes in pediatric B‐cell precursor acute lymphoblastic leukemia with deletions or mutations of IKZF1
L. Olsson, Ferras Albitar, A. Castor, M. Behrendtz +3 more
2015Genes, Chromosomes and Cancer25 citations
Semantic Scholar
Improved cytogenetic characterization and risk stratification of pediatric acute lymphoblastic leukemia using single nucleotide polymorphism array analysis: A single center experience of 296 cases
L. Olsson, Kristina B. Lundin-Ström, A. Castor, M. Behrendtz +4 more
2018Genes, Chromosomes and Cancer24 citations
Semantic Scholar
Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia
Eleanor L. Woodward, Minjun Yang, L. Moura-Castro, H. van den Bos +10 more
2023Nature Communications20 citations Open access
Semantic Scholar
Adherence to childhood cancer treatment: a prospective cohort study from Northern Vietnam
Lan Ngoc Bui, A. Castor, T. Wiebe, J. Toporski +2 more
2019BMJ Open18 citations Open access
Semantic Scholar
Perceptions of important outcomes of moral case deliberations: a qualitative study among healthcare professionals in childhood cancer care
C. Weiner, P. Pergert, B. Molewijk, A. Castor +1 more
2020BMC Medical Ethics14 citations Open access
Semantic Scholar
The genetic landscape of paediatric de novo acute myeloid leukaemia as defined by single nucleotide polymorphism array and exon sequencing of 100 candidate genes
L. Olsson, Sofia Zettermark, Andrea Biloglav, A. Castor +4 more
2016British Journal of Haematology13 citations Open access
Semantic Scholar
Individualized toxicity‐titrated 6‐mercaptopurine increments during high‐dose methotrexate consolidation treatment of lower risk childhood acute lymphoblastic leukaemia. A Nordic Society of Paediatric Haematology and Oncology (NOPHO) pilot study
T. Frandsen, J. Abrahamsson, B. Lausen, K. Vettenranta +7 more
2011British Journal of Haematology12 citations
Semantic Scholar
Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study
Jonatan Källström, R. Niinimäki, Johan Fredlund, Hartmut Vogt +7 more
2024Haematologica11 citations Open access
Semantic Scholar
Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia
Mattias Pilheden, Louise Ahlgren, Axel Hyrenius-Wittsten, V. Gonzalez-Pena +19 more
2022HemaSphere11 citations Open access
Semantic Scholar
Single base substitution mutational signatures in pediatric acute myeloid leukemia based on whole genome sequencing
Rebeqa Gunnarsson, Minjun Yang, Linda Olsson-Arvidsson, Andrea Biloglav +4 more
2021Leukemia10 citations Open access
Semantic Scholar
Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression
Frida Hansson, Jacek Toporski, R. Månsson, Bertil Johansson +6 more
2008Molecular Cancer10 citations Open access
Semantic Scholar
Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia
L. Moura-Castro, Pablo Peña-Martínez, A. Castor, R. Galeev +4 more
2020Genes, Chromosomes and Cancer9 citations Open access
Semantic Scholar
Parents’ and Adolescents’ Preferences for Intensified or Reduced Treatment in Randomized Lymphoblastic Leukemia Trials
M. Tulstrup, H. B. Larsen, A. Castor, P. Rossel +10 more
2016Pediatric Blood & Cancer9 citations
Semantic Scholar
Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Pablo Peña-Martínez +14 more
2024Blood8 citations Open access
Semantic Scholar
Early presentation of osteonecrosis in acute lymphoblastic leukemia: Two children from the Nordic and Baltic cohort
S. S. Mogensen, A. Harila-Saari, T. Frandsen, P. Lähteenmäki +4 more
2017Pediatric Blood & Cancer8 citations
Semantic Scholar
PAX5-ESRRB is a recurrent fusion gene in B-cell precursor pediatric acute lymphoblastic leukemia
Yanara Marincevic-Zuniga, V. Zachariadis, L. Cavelier, A. Castor +9 more
2016Haematologica8 citations Open access
Semantic Scholar
The genomic landscape of relapsed infant and childhood KMT2A-rearranged acute leukemia
Louise Ahlgren, Mattias Pilheden, Helena Sturesson, G. Song +25 more
2025Nature Communications7 citations Open access
Semantic Scholar
Germline whole genome sequencing in pediatric oncology in Denmark—Practitioner perspectives
A. Byrjalsen, U. Stoltze, A. Castor, Ayo Wahlberg
2020Molecular Genetics & Genomic Medicine7 citations Open access
Semantic Scholar
Activating mutations remodel the chromatin accessibility landscape to drive distinct regulatory networks in KMT2A‐rearranged acute leukemia
Qi-Rui Zhang, Ton Falqués-Costa, Mattias Pilheden, Helena Sturesson +8 more
2024HemaSphere5 citations Open access
Semantic Scholar
Parental origin of monosomic chromosomes in near-haploid acute lymphoblastic leukemia
Kristina B. Lundin-Ström, Kristoffer Ström, Andrea Biloglav, G. Barbany +4 more
2020Blood Cancer Journal5 citations Open access
Semantic Scholar
Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia
Rebeqa Gunnarsson, Sebastian DiLorenzo, Kristina B. Lundin-Ström, L. Olsson +11 more
2018Leukemia5 citations Open access
Semantic Scholar
Efficacy and Safety of Imatinib on Top of BFM-Like Chemotherapy in Pediatric Patients with Ph+/BCR-ABL+ Acute Lymphoblastic Leukemia (Ph+ALL). the EsPhALL Study
A. Biondi, M. Schrappe, P. de Lorenzo, A. Castor +13 more
20115 citations
Semantic Scholar
Whole-exome sequencing exploration of acquired uniparental disomies in B-cell precursor acute lymphoblastic leukemia
Kristina B. Lundin-Ström, Andrea Biloglav, H. Lilljebjörn, Marianne Rissler +6 more
2018Leukemia4 citations Open access
Semantic Scholar
Ethical Considerations Regarding the Vaccination of Children—The Power Dynamics Between Doctors and Parents
Mikael Sandlund, I. Engström, A. Castor
2025Acta paediatrica3 citations Open access
Semantic Scholar
Questionnaire‐Based Experimental Study of the Diagnostic Process in Suspected Shaken Baby Syndrome
N. Lynøe, A. Castor, N. Juth, A. Eriksson
2025Annals of the Child Neurology Society2 citations Open access
Semantic Scholar
Constitutional and acquired genetic variants in ARID5B in pediatric B‐cell precursor acute lymphoblastic leukemia
Charlotte Ragnarsson, Minjun Yang, L. Moura-Castro, Efe Aydın +10 more
2024Genes, Chromosomes and Cancer2 citations Open access
Semantic Scholar
SFPQ‐ABL1‐positive B‐cell precursor acute lymphoblastic leukemias
Andrea Biloglav, Linda Olsson-Arvidsson, Johan Theander, M. Behrendtz +2 more
2020Genes, Chromosomes and Cancer2 citations Open access
Semantic Scholar
A Treatment Protocol with Imatinib and Intensive Chemotherapy for Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia: A Single-Arm, Intergroup Study (Esphall 2010)
A. Biondi, V. Gandemer, P. de Lorenzo, G. Cario +15 more
20182 citations Open access
Semantic Scholar
Stem and progenitor cell involvement in acute lymphoblastic leukemia
A. Castor
20072 citations
Semantic Scholar
Constitutional and Somatic Variants in ARID5B in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia
Charlotte Ragnarsson, Minjun Yang, L. Moura-Castro, Rebeqa Gunnarsson +7 more
2023Blood1 citations
Semantic Scholar
Complex genotype-phenotype relationships shape the response to treatment of down syndrome childhood acute lymphoblastic leukaemia
C. Lutz, Virginia A. Turati, R. Clifford, P. Woll +12 more
2022bioRxiv1 citations Open access
Semantic Scholar
Parental origin of monosomy 7 in acute leukaemia
Kristina B. Lundin-Ström, Andrea Biloglav, V. Lazarevic, M. Behrendtz +2 more
2021British Journal of Haematology1 citations Open access
Semantic Scholar

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