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U. Asseline · SciRah

Researcher profile · Semantic Scholar

U. Asseline

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U. Asseline — researcher profile on SciRah

h-index: 27
Works: 112
Citations: 2,164

Most-cited papers

Sequence-specific artificial photo-induced endonucleases based on triple helix-forming oligonucleotides
L. Perrouault, U. Asseline, C. Rivalle, N. T. Thuong +4 more
1990Nature165 citations
Semantic Scholar
Inhibition of simian virus 40 DNA replication in CV-1 cells by an oligodeoxynucleotide covalently linked to an intercalating agent.
Francoise Birg, Daniele Praseuth, Aurelio Zerial, N. T. Thuong +3 more
1990Nucleic Acids Research100 citations Open access
Semantic Scholar
Oligo(alpha-deoxynucleotide)s covalently linked to intercalating agents: differential binding to ribo- and deoxyribopolynucleotides and stability towards nuclease digestion.
N. T. Thuong, U. Asseline, Victoria Roig, M. Takasugi +1 more
1987Proceedings of the National Academy of Sciences of the United States of America92 citations Open access
Semantic Scholar
Development and Applications of Fluorescent Oligonucleotides
U. Asseline
200691 citations
Semantic Scholar
Hydrogen-bonding contacts in the major groove are required for human immunodeficiency virus type-1 tat protein recognition of TAR RNA.
François Hamy, U. Asseline, J. Grasby, S. Iwai +5 more
1993Journal of Molecular Biology79 citations
Semantic Scholar
Triple-helix formation by alpha oligodeoxynucleotides and alpha oligodeoxynucleotide-intercalator conjugates.
Jian-Sheng Sun, C. Giovannangeli, Jean-Christophe François, R. Kurfurst +5 more
1991Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Oligodeoxynucleotides covalently linked to intercalating agents: a new class of gene regulatory substances.
Claude Hélène, T. Montenay-Garestier, T. Saison, M. Takasugi +6 more
1985Biochimie59 citations
Semantic Scholar
Oligo-[α]-deoxynucleotides covalently linked to an intercalating agent. Double helices with parallel strands are formed with complementary oligo-[β]-deoxynucleotides
Jian-Sheng Sun, U. Asseline, D. Rouzaud, T. Montenay-Garestier +2 more
198750 citations Open access
Semantic Scholar
Detection of terminal mismatches on DNA duplexes with fluorescent oligonucleotides.
U. Asseline, M. Chassignol, Y. Aubert, V. Roig
2006Organic and biomolecular chemistry49 citations
Semantic Scholar
New cyanine-oligonucleotide conjugates: relationships between chemical structures and properties.
R. Lartia, U. Asseline
2006Chemistry46 citations
Semantic Scholar
Oligo-2'-deoxyribonucleotides containing uracil modified at the 5-position with linkers ending with guanidinium groups.
V. Roig, U. Asseline
2003Journal of the American Chemical Society45 citations
Semantic Scholar
Solid-phase preparation of 5′,3′-heterobifunctional oligodeoxyribonucleotides using modified solid supports
U. Asseline, E. Bonfils, R. Kurfurst, M. Chassignol +2 more
199241 citations
Semantic Scholar
Synthesis and binding properties of oligo-2'-deoxyribonucleotides covalently linked to a thiazole orange derivative.
Eric J. Privat, U. Asseline
2001Bioconjugate chemistry40 citations
Semantic Scholar
On-line solid phase synthesis of oligonucleotide-peptide hybrids using silica supports
J. Truffert, Olivier Lorthioir, U. Asseline, Thuong Thanh Nguyen +1 more
199439 citations
Semantic Scholar
A theoretical and experimental study of two thiazole orange derivatives with single- and double-stranded oligonucleotides, polydeoxyribonucleotides and DNA.
S. Prodhomme, Jean-Philippe Demaret, S. Vinogradov, U. Asseline +2 more
1999Journal of Photochemistry and Photobiology. B: Biology34 citations
Semantic Scholar
SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES COVALENTLY LINKED TO INTERCALATING AGENTS
U. Asseline, N. T. Thuong, C. Héléne
199733 citations
Semantic Scholar
Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities
E. Brunet, Maddalena Corgnali, L. Perrouault, V. Roig +5 more
2005Nucleic Acids Research32 citations Open access
Semantic Scholar
Oligonucleotide-conjugated Thiazole Orange Probes as “Light-up” Probes for Messenger Ribonucleic Acid Molecules in Living Cells¶
Eric J. Privat, T. Melvin, U. Asseline, P. Vigny
2001Photochemistry and Photobiology32 citations
Semantic Scholar
Synthesis, purification and characterization of two peptide-oligonucleotide conjugates as potential artificial nucleases
J. Truffert, U. Asseline, A. Brack, Thuong Thanh Nguyen
199632 citations
Semantic Scholar
Synthesis and physicochemical properties of oligonucleotides built with either α-L or β-L nucleotides units and covalently linked to an acridine derivative
U. Asseline, Jean-François Hau, C. Stanislas, Thierry Le Diguarher +3 more
199132 citations Open access
Semantic Scholar
Asymmetric recognition of psoralen interstrand crosslinks by the nucleotide excision repair and the error-prone repair pathways.
François-Xavier Barre, U. Asseline, Annick Harel-Bellan
1999Journal of Molecular Biology30 citations
Semantic Scholar
New solid-phase for automated synthesis of oligonucleotides containing an amino-alkyl linker at their 3′-end
U. Asseline, T. T. Nguyen
199030 citations
Semantic Scholar
Solid-phase synthesis of modified oligodeoxyribonucleotides with an acridine derivative or a thiophosphate group at their 3′end
U. Asseline, N. T. Thuong
198930 citations
Semantic Scholar
Smoothing of the thermal stability of DNA duplexes by using modified nucleosides and chaotropic agents.
Hong-Khanh Nguyen, Olivier Fournier, U. Asseline, D. Dupret +1 more
1999Nucleic Acids Research29 citations Open access
Semantic Scholar
Psoralen adducts induced by triplex-forming oligonucleotides are refractory to repair in HeLa cells.
Anne-Laure Guieysse, Danièle Praseuth, C. Giovannangeli, U. Asseline +1 more
2000Journal of Molecular Biology26 citations
Semantic Scholar
Optimized synthesis of phosphorothioate oligodeoxyribonucleotides substituted with a 5'-protected thiol function and a 3'-amino group.
Yves Aubert, Sylvain Bourgerie, Laurent Meunier, Roger Mayer +4 more
2000Nucleic Acids Research25 citations Open access
Semantic Scholar
Synthesis and hybridization properties of oligonucleotide-perylene conjugates: influence of the conjugation parameters on triplex and duplex stabilities.
Y. Aubert, U. Asseline
2004Organic and biomolecular chemistry23 citations
Semantic Scholar
Synthesis and binding properties of oligonucleotides covalently linked to an acridine derivative: new study of the influence of the dye attachment site.
U. Asseline, Edwige Bonfils, D. Dupret, N. T. Thuong
1996Bioconjugate chemistry23 citations
Semantic Scholar
Recognition of alternating oligopurine/oligopyrimidine tracts of DNA by oligonucleotides with base-to-base linkages.
Bei-wen Zhou, Christophe Marchand, U. Asseline, N. T. Thuong +3 more
1995Bioconjugate chemistry22 citations
Semantic Scholar
Fluorinated squaraine as near-IR label with improved properties for the labeling of oligonucleotides
Brice-Loïc Renard, Y. Aubert, U. Asseline
200921 citations
Semantic Scholar
Fluorescent Properties of Oligonucleotide‐conjugated Thiazole Orange Probes ¶
Eric J. Privat, T. Melvin, F. Mérola, Gerd Schweizer +3 more
2002Photochemistry and Photobiology19 citations
Semantic Scholar
Modification of DNA duplexes to smooth their thermal stability independently of their base content for DNA sequencing by hybridization.
Hong-Khanh Nguyen, P. Auffray, U. Asseline, D. Dupret +1 more
1997Nucleic Acids Research19 citations Open access
Semantic Scholar
Oligo-α-deoxyribonucleotides with a modified nucleic base and covalently linked to reactive agents
R. Kurfurst, V. Roig, M. Chassignol, U. Asseline +1 more
199319 citations
Semantic Scholar
Recognition and Photo-Induced Cleavage and Cross-Linking of Nucleic Acids by Oligonucleotides Covalently Linked to Ellipticine
T. Le Doan, L. Perrouault, U. Asseline, N. T. Thuong +3 more
1991Antisense Research and Development19 citations
Semantic Scholar
Oligothymidylates covalently linked to an acridine derivative and with modified phosphodiester backbone: circular dichroism studies of their interactions with complementary sequences.
M. Durand, J. Maurizot, U. Asseline, C. Barbier +2 more
1989Nucleic Acids Research18 citations Open access
Semantic Scholar
Triplex-forming oligonucleotide–orthophenanthroline conjugates for efficient targeted genome modification
Fabio Cannata, E. Brunet, L. Perrouault, V. Roig +4 more
2008Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar
Photochemically and chemically activatable antisense oligonucleotides: comparison of their reactivities towards DNA and RNA targets.
G. Godard, Jean-Christophe François, Isabelle Duroux, U. Asseline +4 more
1994Nucleic Acids Research17 citations Open access
Semantic Scholar
Synthesis of oligonucleotides containing a carboxyl group at either their 5′ end or their 3′ end and their subsequent derivatization by an intercalating agent
M. Gottikh, U. Asseline, N. T. Thuong
199017 citations
Semantic Scholar
Improved nuclear delivery of antisense 2'‐Ome RNA by conjugation with the histidine‐rich peptide H5WYG
U. Asseline, Cristine Gonçalves, C. Pichon, P. Midoux
2014Journal of Gene Medicine16 citations
Semantic Scholar
Synthesis and binding properties of perylene-oligo-2′-deoxyribonucleotide conjugates
U. Asseline, Eric Cheng
200116 citations
Semantic Scholar
NMR studies of complex formation between the modified oligonucleotide d(T*TCTGT) covalently linked to an acridine derivative and its complementary sequence d(GCACAGAA).
G. Lancelot, J. Guesnet, U. Asseline, N. T. Thuong
1988Biochemistry16 citations
Semantic Scholar
Synthesis and properties of triple helix-forming oligodeoxyribonucleotides containing 7-chloro-7-deaza-2'-deoxyguanosine.
Yves Aubert, Loïc Perrouault, Claude Hélène, C. Giovannangeli +1 more
2001Bioorganic & Medicinal Chemistry15 citations
Semantic Scholar
Oligonucleotides tethered via nucleic bases. A potential new set of compounds for alternate strand triple-helix formation
U. Asseline, Thuong Thanh Nguyen
199315 citations
Semantic Scholar
Targeting DNA with "light-up" pyrimidine triple-helical forming oligonucleotides conjugated to stabilizing fluorophores (LU-TFOs).
Brice-Loïc Renard, R. Lartia, U. Asseline
2008Organic and biomolecular chemistry14 citations
Semantic Scholar
New reagent for the preparation of oligonucleotides involving a 5′-thiophosphate or a 5′-phosphate group☆
R. Lartia, U. Asseline
200414 citations
Semantic Scholar
Synthesis and properties of oligo-2'-deoxyribonucleotides containing internucleotidic phosphoramidate linkages modified with pendant groups ending with either two amino or two hydroxyl functions.
U. Asseline, M. Chassignol, J. Draus, M. Durand +1 more
2003Bioorganic & Medicinal Chemistry14 citations
Semantic Scholar
5′-5′ tethered oligonucleotides via nucleic bases: A potential new set of compounds for alternate strand triple-helix formation
U. Asseline, Thuong Thanh Nguyen
199414 citations
Semantic Scholar
The stability of duplexes involving AT and/or G4EtC base pairs is not dependent on their AT/G4EtC ratio content. Implication for DNA sequencing by hybridization.
Hong-Khanh Nguyen, Edwige Bonfils, P. Auffray, Patricia Costaglioli +6 more
1998Nucleic Acids Research13 citations Open access
Semantic Scholar
Pyrazolo[1,5-a]-1,3,5-triazine C-nucleoside as deoxyadenosine analogue: synthesis, pairing, and resistance to hydrolysis.
M. Lefoix, G. Mathis, Tirtsa Kleinmann, J. Truffert +1 more
2014Journal of Organic Chemistry12 citations
Semantic Scholar
Model of a DNA-Protein Complex of the Architectural Monomeric Protein MC1 from Euryarchaea
F. Paquet, O. Delalande, S. Goffinont, F. Culard +4 more
2014PLoS ONE12 citations Open access
Semantic Scholar

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