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K. Storbeck · SciRah

Researcher profile · Semantic Scholar

K. Storbeck

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K. Storbeck — researcher profile on SciRah

h-index: 30
Works: 118
Citations: 3,202

Most-cited papers

Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review
L. Schiffer, Lise Barnard, E. Baranowski, L. Gilligan +4 more
2019Journal of Steroid Biochemistry and Molecular Biology375 citations Open access
Semantic Scholar
11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome
M. O'Reilly, Punith Kempegowda, C. Jenkinson, A. Taylor +3 more
2017220 citations
Semantic Scholar
Intracrine androgen biosynthesis, metabolism and action revisited
L. Schiffer, W. Arlt, K. Storbeck
2017Molecular and Cellular Endocrinology193 citations Open access
Semantic Scholar
11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: a putative role in castration resistant prostate cancer?
K. Storbeck, Liezl M. Bloem, Donita Africander, Lindie Schloms +2 more
2013Molecular and Cellular Endocrinology173 citations
Semantic Scholar
11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which Can No Longer Be Ignored
Elzette Pretorius, Donita Africander, M. Vlok, Meghan S Perkins +2 more
2016PLoS ONE141 citations Open access
Semantic Scholar
A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids.
Elzette Pretorius, W. Arlt, K. Storbeck
2017Molecular and Cellular Endocrinology130 citations Open access
Semantic Scholar
Steroid Metabolome Analysis in Disorders of Adrenal Steroid Biosynthesis and Metabolism
K. Storbeck, L. Schiffer, E. Baranowski, V. Chortis +7 more
2019Endocrine reviews112 citations Open access
Semantic Scholar
The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: quantification of steroid intermediates and end products in H295R cells.
Lindie Schloms, K. Storbeck, P. Swart, W. Gelderblom +1 more
2012Journal of Steroid Biochemistry and Molecular Biology96 citations
Semantic Scholar
11β-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione.
A. Swart, Lindie Schloms, K. Storbeck, Liezl M. Bloem +4 more
2013Journal of Steroid Biochemistry and Molecular Biology93 citations
Semantic Scholar
High-throughput analysis of 19 endogenous androgenic steroids by ultra-performance convergence chromatography tandem mass spectrometry.
J. Quanson, M. Stander, Elzette Pretorius, C. Jenkinson +2 more
2016Journal of chromatography. B, Analytical technologies in the biomedical and life sciences80 citations Open access
Semantic Scholar
11-Oxygenated androgen precursors are the preferred substrates for aldo-keto reductase 1C3 (AKR1C3): implications for castration resistant prostate cancer.
M. Barnard, J. Quanson, E. Mostaghel, Elzette Pretorius +2 more
2018Journal of Steroid Biochemistry and Molecular Biology68 citations Open access
Semantic Scholar
11β-Hydroxyandrostenedione: Downstream metabolism by 11βHSD, 17βHSD and SRD5A produces novel substrates in familiar pathways.
A. Swart, K. Storbeck
2015Molecular and Cellular Endocrinology62 citations
Semantic Scholar
Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia
Christopher M. Jones, A. Mallappa, N. Reisch, Nikolaos Nikolaou +9 more
2016Journal of Clinical Endocrinology and Metabolism59 citations Open access
Semantic Scholar
The role of adrenal derived androgens in castration resistant prostate cancer
M. Barnard, E. Mostaghel, R. Auchus, K. Storbeck
2019Journal of Steroid Biochemistry and Molecular Biology57 citations Open access
Semantic Scholar
11β-Hydroxyandrostenedione Returns to the Steroid Arena: Biosynthesis, Metabolism and Function
Liezl M. Bloem, K. Storbeck, Lindie Schloms, A. Swart
2013Molecules57 citations Open access
Semantic Scholar
A comparative study of the androgenic properties of progesterone and the progestins, medroxyprogesterone acetate (MPA) and norethisterone acetate (NET-A).
Donita Africander, K. Storbeck, J. Hapgood
2014Journal of Steroid Biochemistry and Molecular Biology53 citations
Semantic Scholar
Advances in the analytical methodologies: Profiling steroids in familiar pathways-challenging dogmas.
Liezl M. Bloem, K. Storbeck, P. Swart, Therina du Toit +2 more
2015Journal of Steroid Biochemistry and Molecular Biology51 citations
Semantic Scholar
The clinical and biochemical significance of 11-oxygenated androgens in human health and disease.
K. Storbeck, M. O'Reilly
2023European Journal of Endocrinology49 citations Open access
Semantic Scholar
11βHSD1 Inhibition with AZD4017 Improves Lipid Profiles and Lean Muscle Mass in Idiopathic Intracranial Hypertension
R. Hardy, H. Botfield, K. Markey, J. Mitchell +15 more
2020Journal of Clinical Endocrinology and Metabolism46 citations Open access
Semantic Scholar
Multi-steroid profiling by UHPLC-MS/MS with post-column infusion of ammonium fluoride.
L. Schiffer, F. Shaheen, L. Gilligan, K. Storbeck +4 more
2022Journal of chromatography. B, Analytical technologies in the biomedical and life sciences44 citations Open access
Semantic Scholar
The utility of ultra-high performance supercritical fluid chromatography-tandem mass spectrometry (UHPSFC-MS/MS) for clinically relevant steroid analysis.
K. Storbeck, L. Gilligan, C. Jenkinson, E. Baranowski +3 more
2018Journal of chromatography. B, Analytical technologies in the biomedical and life sciences43 citations Open access
Semantic Scholar
Cytochrome b5: novel roles in steroidogenesis.
K. Storbeck, A. Swart, P. Goosen, P. Swart
2013Molecular and Cellular Endocrinology41 citations
Semantic Scholar
Steroid metabolism in breast cancer: Where are we and what are we missing?
Donita Africander, K. Storbeck
2017Molecular and Cellular Endocrinology35 citations
Semantic Scholar
Revisiting classical 3β-hydroxysteroid dehydrogenase 2 deficiency: lessons from 31 pediatric cases.
T. Guran, C. Kara, M. Yıldız, E. Bitkin +21 more
2020Journal of Clinical Endocrinology and Metabolism34 citations Open access
Semantic Scholar
Bidirectional crosstalk between Hypoxia-Inducible Factor and glucocorticoid signalling in zebrafish larvae
Davide Marchi, Kirankumar Santhakumar, E. Markham, Nan Li +4 more
2020PLoS Genetics34 citations Open access
Semantic Scholar
The P450 side chain cleavage enzyme Cyp11a2 facilitates steroidogenesis in zebrafish.
Nan Li, J. A. Oakes, K. Storbeck, V. Cunliffe +1 more
2019Journal of Endocrinology31 citations Open access
Semantic Scholar
Cytochrome b5 modulates multiple reactions in steroidogenesis by diverse mechanisms.
K. Storbeck, A. Swart, C. Fox, P. Swart
2015Journal of Steroid Biochemistry and Molecular Biology30 citations
Semantic Scholar
11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome
M. O'Reilly, P. Kempegowda, C. Jenkinson, Angela E. Taylor +3 more
2016Journal of Clinical Endocrinology and Metabolism29 citations Open access
Semantic Scholar
Clinical and hormonal profiles correlate with molecular characteristics in patients with 11β-hydroxylase deficiency.
M. Yıldız, E. Işik, Z. Y. Abalı, M. Keskin +22 more
2021Journal of Clinical Endocrinology and Metabolism25 citations Open access
Semantic Scholar
Rooibos influences glucocorticoid levels and steroid ratios in vivo and in vitro: a natural approach in the management of stress and metabolic disorders?
Lindie Schloms, Carine Smith, K. Storbeck, Jeanine L. Marnewick +2 more
2014Molecular Nutrition & Food Research25 citations
Semantic Scholar
Analysis of multiple vitamin D metabolites by ultra-performance supercritical fluid chromatography-tandem mass spectrometry (UPSFC-MS/MS).
C. Jenkinson, A. Taylor, K. Storbeck, M. Hewison
2018Journal of chromatography. B, Analytical technologies in the biomedical and life sciences23 citations Open access
Semantic Scholar
University of Birmingham Genetic disruption of 21-hydroxylase in zebrafish causes interrenal hyperplasia
H. Eachus, A. Zaucker, J. A. Oakes, A. Griffin +10 more
201723 citations
Semantic Scholar
11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool
Lise Barnard, L. Schiffer, Renate Louw du-Toit, J. Tamblyn +5 more
2020Endocrinology22 citations Open access
Semantic Scholar
Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis.
C. Martin, A. Crastin, M. Sagmeister, M. S. Kalirai +16 more
2024Journal of Autoimmunity21 citations Open access
Semantic Scholar
The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1.
Lise Barnard, N. Nikolaou, C. Louw, L. Schiffer +7 more
2020Journal of Steroid Biochemistry and Molecular Biology21 citations Open access
Semantic Scholar
Expression and activity profiling of the steroidogenic enzymes of glucocorticoid biosynthesis and the fdx1 co‐factors in zebrafish
M. Weger, N. Diotel, B. Weger, T. Beil +10 more
2018Journal of neuroendocrinology21 citations
Semantic Scholar
Progestins used in endocrine therapy and the implications for the biosynthesis and metabolism of endogenous steroid hormones.
Renate Louw-du Toit, K. Storbeck, M. Cartwright, Angelique Cabral +1 more
2017Molecular and Cellular Endocrinology20 citations
Semantic Scholar
Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens
L. Schiffer, Alicia Bossey, Punith Kempegowda, A. Taylor +4 more
2021European Journal of Endocrinology18 citations Open access
Semantic Scholar
Ferredoxin 1b deficiency leads to testis disorganization, impaired spermatogenesis and feminization in zebrafish.
J. A. Oakes, Nan Li, Belinda Wistow, A. Griffin +4 more
2019Endocrinology16 citations Open access
Semantic Scholar
11β-hydroxylase loss disrupts steroidogenesis and reproductive function in zebrafish.
J. A. Oakes, Lise Barnard, K. Storbeck, V. Cunliffe +1 more
2020Journal of Endocrinology15 citations Open access
Semantic Scholar
Cytochrome b5 augments 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase activity.
P. Goosen, K. Storbeck, A. Swart, R. Conradie +1 more
2011Journal of Steroid Biochemistry and Molecular Biology15 citations
Semantic Scholar
Inhibition of the glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 drives concurrent 11-oxygenated androgen excess
L. Schiffer, Imken Oestlund, J. Snoep, L. Gilligan +8 more
2023bioRxiv12 citations Open access
Semantic Scholar
Canonical and Noncanonical Androgen Metabolism and Activity.
K. Storbeck, E. Mostaghel
2019Advances in Experimental Medicine and Biology12 citations
Semantic Scholar
Fourth-Generation Progestins Inhibit 3β-Hydroxysteroid Dehydrogenase Type 2 and Modulate the Biosynthesis of Endogenous Steroids
Renate Louw-du Toit, Meghan S Perkins, J. Snoep, K. Storbeck +1 more
2016PLoS ONE12 citations Open access
Semantic Scholar
Cortisol production in sheep is influenced by the functional expression of two cytochrome P450 17α-hydroxylase/17,20-lyase (CYP17) isoforms.
D. Hough, S. Cloete, K. Storbeck, A. Swart +1 more
2013Journal of Animal Science11 citations
Semantic Scholar
Allosteric interaction between 3β‐hydroxysteroid dehydrogenase/Δ5‐Δ4 isomerase and cytochrome b5 influences cofactor binding
P. Goosen, A. Swart, K. Storbeck, P. Swart
2013The FASEB Journal11 citations
Semantic Scholar
The glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 catalyzes the activation of testosterone.
Imken Oestlund, Jacky L. Snoep, L. Schiffer, M. Wabitsch +2 more
2023Journal of Steroid Biochemistry and Molecular Biology10 citations Open access
Semantic Scholar
Genetic Disruption of 21-Hydroxylase in Zebrafish Causes Interrenal Hyperplasia
H. Eachus, A. Zaucker, J. A. Oakes, A. Griffin +10 more
2017Endocrinology10 citations Open access
Semantic Scholar
Misreporting contraceptive use and the association of peak study progestin levels with weight and BMI among women randomized to the progestin-only injectable contraceptives DMPA-IM and NET-EN
Chanel Avenant, Alexis J. Bick, Salndave B. Skosana, Sigcinile Dlamini +13 more
2023PLoS ONE8 citations Open access
Semantic Scholar
Relative contribution of P450c17 towards the acute cortisol response: Lessons from sheep and goats.
D. Hough, K. Storbeck, S. Cloete, A. Swart +1 more
2015Molecular and Cellular Endocrinology8 citations
Semantic Scholar

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