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T. Grunewald · SciRah

Researcher profile · Semantic Scholar

T. Grunewald

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T. Grunewald — researcher profile on SciRah

h-index: 28
Works: 60
Citations: 2,579

Most-cited papers

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis.
Amal M. El-Naggar, Chansey J. Veinotte, Hongwei Cheng, T. Grunewald +21 more
2015Cancer Cell267 citations Open access
Semantic Scholar
YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1
S. Somasekharan, Amal M. El-Naggar, G. Leprivier, Hongwei Cheng +9 more
2015Journal of Cell Biology252 citations Open access
Semantic Scholar
Lysophosphatidic acid (LPA) signalling in cell migration and cancer invasion: A focussed review and analysis of LPA receptor gene expression on the basis of more than 1700 cancer microarrays
Semjon Willier, E. Butt, T. Grunewald
2013Biology of the Cell141 citations
Semantic Scholar
STEAP1 Is Associated with the Invasive and Oxidative Stress Phenotype of Ewing Tumors
T. Grunewald, I. Diebold, I. Esposito, Stephanie Plehm +16 more
2011Molecular Cancer Research125 citations Open access
Semantic Scholar
Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localisation
T. Grunewald, U. Kämmerer, C. Winkler, D. Schindler +3 more
2007British Journal of Cancer123 citations Open access
Semantic Scholar
Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells.
T. Grunewald, U. Kammerer, Elfriede Schulze, D. Schindler +3 more
2006Experimental Cell Research119 citations
Semantic Scholar
The STEAP protein family: Versatile oxidoreductases and targets for cancer immunotherapy with overlapping and distinct cellular functions
T. Grunewald, H. Bach, A. Cossarizza, I. Matsumoto
2012Biology of the Cell103 citations Open access
Semantic Scholar
Tumour‐derived exosomes: Tiny envelopes for big stories
Isabella V. Miller, T. Grunewald
2015Biology of the Cell86 citations
Semantic Scholar
The LIM and SH3 domain protein family: structural proteins or signal transducers or both?
T. Grunewald, E. Butt
2008Molecular Cancer83 citations Open access
Semantic Scholar
An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein
M. F. Orth, A. Cazes, E. Butt, T. Grunewald
2014OncoTarget77 citations Open access
Semantic Scholar
First report of effective and feasible treatment of multifocal lymphangiomatosis (Gorham-Stout) with bevacizumab in a child.
T. Grunewald, L. Damke, M. Maschan, U. Petrova +8 more
2010Annals of Oncology77 citations Open access
Semantic Scholar
Cancer esearch apeutics , Targets , and Chemical Biology e of LIM and SH 3 Protein 1 ( LASP 1 ) in the Metastatic R emination of Medulloblastoma
Opher Traenka, M. Remke, A. Korshunov, S. Bender +16 more
201071 citations
Semantic Scholar
Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma
T. Grunewald, U. Kammerer, M. Kapp, M. Eck +3 more
2007BMC Cancer69 citations Open access
Semantic Scholar
Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration
Amelie Hailer, T. Grunewald, M. F. Orth, C. Reiss +3 more
2014OncoTarget66 citations Open access
Semantic Scholar
DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma.
K. Hauer, J. Calzada-Wack, K. Steiger, T. Grunewald +7 more
2013Cancer Research66 citations Open access
Semantic Scholar
First identification of Ewing's sarcoma‐derived extracellular vesicles and exploration of their biological and potential diagnostic implications
Isabella V. Miller, G. Raposo, U. Welsch, Olivia Prazeres da Costa +8 more
2013Biology of the Cell66 citations
Semantic Scholar
G‐Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1
G. Richter, A. Fasan, K. Hauer, T. Grunewald +7 more
2013Journal of Pathology66 citations
Semantic Scholar
The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer
D. Sahay, R. Leblanc, T. Grunewald, Srikant Ambatipudi +3 more
2015OncoTarget65 citations Open access
Semantic Scholar
Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer
Jochen J. Frietsch, T. Grunewald, S. Jasper, U. Kämmerer +4 more
2010British Journal of Cancer61 citations Open access
Semantic Scholar
Cell Adhesion and Transcriptional Activity - Defining the Role of the Novel Protooncogene LPP.
T. Grunewald, Saskia M Pasedag, E. Butt
2009Translational Oncology56 citations Open access
Semantic Scholar
High STEAP1 expression is associated with improved outcome of Ewing's sarcoma patients.
T. Grunewald, A. Ranft, Irene Esposito, P. da Silva-Buttkus +10 more
2012Annals of Oncology52 citations Open access
Semantic Scholar
Defining the role of TRIP6 in cell physiology and cancer
Semjon Willier, E. Butt, G. Richter, S. Burdach +1 more
2011Biology of the Cell44 citations
Semantic Scholar
Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers
B. Rotblat, T. Grunewald, G. Leprivier, G. Melino +1 more
2013OncoTarget42 citations Open access
Semantic Scholar
Mesenchymal stromal cells for treatment of steroid-refractory GvHD: a review of the literature and two pediatric cases
C. Wernicke, T. Grunewald, J. Hendrik, S. Kuçi +10 more
2011International Archives of Medicine41 citations Open access
Semantic Scholar
Understanding tumor heterogeneity as functional compartments - superorganisms revisited
T. Grunewald, S. M. Herbst, J. Heinze, S. Burdach
2011Journal of Translational Medicine40 citations Open access
Semantic Scholar
Sclerosing Epithelioid Fibrosarcoma of the Bone: A Case Report of High Resistance to Chemotherapy and a Survey of the Literature
T. Grunewald, I. von Luettichau, G. Weirich, A. Wawer +6 more
2010Sarcoma36 citations Open access
Semantic Scholar
The Zyxin‐related protein thyroid receptor interacting protein 6 (TRIP6) is overexpressed in Ewing's sarcoma and promotes migration, invasion and cell growth
T. Grunewald, Semjon Willier, D. Janik, R. Unland +8 more
2013Biology of the Cell35 citations
Semantic Scholar
Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation.
J. Engel, A. Honig, Tanja Schönhals, C. Weidler +7 more
2008European Journal of Obstetrics, Gynecology, and Reproductive Biology29 citations
Semantic Scholar
Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow
U. Thiel, A. Wawer, I. von Luettichau, H. Bender +13 more
2016OncoTarget23 citations Open access
Semantic Scholar
Ewing sarcoma partial regression without GvHD by chondromodulin-I/HLA-A*02:01-specific allorestricted T cell receptor transgenic T cells
U. Thiel, S. J. Schober, I. Einspieler, Andreas Kirschner +15 more
2017Oncoimmunology22 citations Open access
Semantic Scholar
MondoA is highly overexpressed in acute lymphoblastic leukemia cells and modulates their metabolism, differentiation and survival.
C. Wernicke, G. Richter, B. Beinvogl, Stephanie Plehm +9 more
2012Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis22 citations
Semantic Scholar
Human HLA-A*02:01/CHM1+ allo-restricted T cell receptor transgenic CD8+ T Cells specifically inhibit Ewing sarcoma growth in vitro and in vivo
Franziska Blaeschke, U. Thiel, Andreas Kirschner, M. Thiede +11 more
2016OncoTarget21 citations Open access
Semantic Scholar
LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia
Jochen J. Frietsch, C. Kastner, T. Grunewald, H. Schweigel +6 more
2014OncoTarget21 citations Open access
Semantic Scholar
Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma.
B. Shannan, J. Matschke, H. Chauvistré, F. Vogel +28 more
2019European Journal of Cancer20 citations
Semantic Scholar
First report of ectopic ACTH syndrome and PTHrP-induced hypercalcemia due to a hepatoblastoma in a child.
T. Grunewald, I. von Luettichau, U. Welsch, H. Dörr +4 more
2010European Journal of Endocrinology20 citations
Semantic Scholar
Targeted Therapeutics in Treatment of Children and Young Adults with Solid Tumors: an Expert Survey and Review of the Literature
T. Grunewald, N. Greulich, U. Kontny, M. Frühwald +10 more
2012Klinische Pädiatrie19 citations
Semantic Scholar
Hippo pathway effectors YAP1/TAZ induce a EWS-FLI1-opposing gene signature and associate with disease progression in Ewing Sarcoma
Pablo Rodríguez-Núñez, L. Romero-Pérez, A. T. Amaral, P. Puerto-Camacho +5 more
2019bioRxiv13 citations Open access
Semantic Scholar
Translational Aspects of Epithelioid Sarcoma – Current Consensus
T. Grunewald, S. Postel-Vinay, R. Nakayama, N. Berlow +22 more
2023Clinical Cancer Research12 citations Open access
Semantic Scholar
LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression
A. S., H. Poppe, R. Houben, T. Grunewald +2 more
2015PLoS ONE11 citations Open access
Semantic Scholar
Cancer Genes and Genomics STEAP 1 Is Associated with the Invasive and Oxidative Stress Phenotype of Ewing Tumors
T. Grunewald, I. Diebold, I. Esposito, Stephanie Plehm +15 more
201111 citations
Semantic Scholar
Erratum to “Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells” [Exp. Cell Res. 312 (2006) 974–982]
T. Grunewald, Ulrike Kammerer, Elfriede Schulze, D. Schindler +3 more
20064 citations
Semantic Scholar
Coopération entre mutation somatique et variant génétique de susceptibilité dans le sarcome d’Ewing
T. Grunewald, Pascale Gilardi-Hebenstreit, P. Charnay, O. Delattre
20162 citations Open access
Semantic Scholar
Abstract 4515: Metabolic stress sensor MondoA mediatesin vivoaggressiveness of common ALL by induction of HIF1α
A. Sipol, T. Grunewald, Juliane Schmaeh, M. D. den Boer +7 more
20171 citations
Semantic Scholar
Abstract 2462: MondoA mediatesin vivoaggressiveness of common ALL and may serve as a T-cell immunotherapy target
A. Sipol, T. Grunewald, Juliane Schmaeh, David A. Schirmer +9 more
20161 citations
Semantic Scholar
Translating cancer-omics into function
B. Rotblat, T. Grunewald
20151 citations
Semantic Scholar
Abstract 647: EWSR1::FLI1 suppresses ribosome biogenesis and creates a targetable vulnerability in Ewing sarcoma.
Matteo Colombo, Jason Sims, Christoph P. Dotter, Hana Bernhardova +15 more
2026Cancer Research0 citations
Semantic Scholar
Genomic landscape of Ewing sarcoma: a pooled analysis of 538 cases and clinicopathological correlation
L. Romero-Pérez, C. Hénon, A. Ranft, J. Díaz-Martín +4 more
2026medRxiv0 citations Open access
Semantic Scholar
Abstract B048: The Ewing Sarcoma Institute – a catalyst to improve outcomes for patients with Ewing sarcoma globally
H. Kovar, J. Amatruda, Carol Basso, C. Brown +13 more
2025Cancer Research0 citations
Semantic Scholar
Abstract B38: Ewing sarcoma regression without GVHD by allo-MHC/CHM1 specific T cells
U. Thiel, S. J. Schober, I. Einspieler, Andreas Kirschner +9 more
20180 citations
Semantic Scholar
Abstract 3757: Ewing Sarcoma regression by Allo-MHC/Chm1 specific T cells without GVHD
U. Thiel, S. J. Schober, I. Einspieler, Andreas Kirschner +6 more
20170 citations
Semantic Scholar

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