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G. Fròsina · SciRah

Researcher profile · Semantic Scholar

G. Fròsina

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G. Fròsina — researcher profile on SciRah

h-index: 22
Works: 84
Citations: 2,791

Most-cited papers

Two Pathways for Base Excision Repair in Mammalian Cells (*)
G. Fròsina, P. Fortini, O. Rossi, F. Carrozzino +5 more
1996Journal of Biological Chemistry534 citations Open access
Semantic Scholar
Involvement of XRCC1 and DNA Ligase III Gene Products in DNA Base Excision Repair*
E. Cappelli, Richard M. Taylor, Michela Cevasco, A. Abbondandolo +2 more
1997Journal of Biological Chemistry353 citations Open access
Semantic Scholar
Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair.
M. Alcalay, Natalia Meani, V. Gelmetti, Anna Fantozzi +14 more
2003Journal of Clinical Investigation273 citations Open access
Semantic Scholar
Comparative Analysis of DNA Repair in Stem and Nonstem Glioma Cell Cultures
M. Ropolo, A. Daga, Fabrizio Griffero, Mara Foresta +8 more
2009Molecular Cancer Research203 citations Open access
Semantic Scholar
DNA Repair and Resistance of Gliomas to Chemotherapy and Radiotherapy
G. Fròsina
2009Molecular Cancer Research187 citations Open access
Semantic Scholar
The role of CSA in the response to oxidative DNA damage in human cells
M. D'Errico, E. Parlanti, M. Teson, P. Degan +12 more
2007Oncogene134 citations Open access
Semantic Scholar
Predictability, efficacy and safety of radiosensitization of glioblastoma‐initiating cells by the ATM inhibitor KU‐60019
D. Vecchio, A. Daga, E. Carra, D. Marubbi +11 more
2014International Journal of Cancer69 citations Open access
Semantic Scholar
Pharmacokinetics, pharmacodynamics and efficacy on pediatric tumors of the glioma radiosensitizer KU60019
D. Vecchio, A. Daga, E. Carra, D. Marubbi +12 more
2015International Journal of Cancer57 citations Open access
Semantic Scholar
The current evidence for an adaptive response to alkylating agents in mammalian cells, with special reference to experiments with in vitro cell cultures.
G. Fròsina, Angelo Abbondandolo
1985Mutation research55 citations
Semantic Scholar
The Bright and the Dark Sides of DNA Repair in Stem Cells
G. Fròsina
2010Journal of Biomedicine and Biotechnology41 citations Open access
Semantic Scholar
Characterization of Glioma Stem Cells Through Multiple Stem Cell Markers and Their Specific Sensitization to Double‐Strand Break‐Inducing Agents by Pharmacological Inhibition of Ataxia Telangiectasia Mutated Protein
A. Raso, D. Vecchio, E. Cappelli, M. Ropolo +8 more
2012Brain Pathology39 citations Open access
Semantic Scholar
AP endonuclease activity in humans: development of a simple assay and analysis of ten normal individuals.
A. Redaelli, R. Magrassi, S. Bonassi, A. Abbondandolo +1 more
1998Teratogenesis, carcinogenesis, and mutagenesis (Print)39 citations Open access
Semantic Scholar
Blocking epithelial-to-mesenchymal transition in glioblastoma with a sextet of repurposed drugs: the EIS regimen
R. Kast, Nicolas Skuli, G. Karpel-Massler, G. Fròsina +2 more
2017OncoTarget36 citations Open access
Semantic Scholar
Role of the DNA ligase III zinc finger in polynucleotide binding and ligation.
Richard M. Taylor, Jenna Whitehouse, E. Cappelli, G. Fròsina +1 more
1998Nucleic Acids Research36 citations Open access
Semantic Scholar
CommentaryDNA Base Excision Repair Defects in Human Pathologies
G. Fròsina
2004Free radical research35 citations
Semantic Scholar
Recapitulating the Key Advances in the Diagnosis and Prognosis of High-Grade Gliomas: Second Half of 2021 Update
G. Fròsina
2023International Journal of Molecular Sciences34 citations Open access
Semantic Scholar
ATR kinase inhibitors NVP-BEZ235 and AZD6738 effectively penetrate the brain after systemic administration
G. Fròsina, A. Profumo, D. Marubbi, D. Marcello +2 more
2018Radiation Oncology33 citations Open access
Semantic Scholar
Limited advances in therapy of glioblastoma trigger re-consideration of research policy.
G. Fròsina
2015Critical reviews in oncology/hematology32 citations
Semantic Scholar
The O6-methylguanine-DNA activity of rat hepatoma cells is increased after a single exposure to alkylating agents
G. Fròsina, F. Laval
198731 citations
Semantic Scholar
DNA repair in normal and cancer stem cells, with special reference to the central nervous system.
G. Fròsina
2009Current Medicinal Chemistry30 citations
Semantic Scholar
Nanoparticle-mediated drug delivery to high-grade gliomas.
G. Fròsina
2016Nanomedicine : nanotechnology, biology, and medicine25 citations
Semantic Scholar
Complementation of the oxidatively damaged DNA repair defect in Cockayne syndrome A and B cells by Escherichia coli formamidopyrimidine DNA glycosylase.
M. Ropolo, P. Degan, Mara Foresta, M. D'Errico +6 more
2007Free Radical Biology & Medicine23 citations
Semantic Scholar
The current evidence for defective repair of oxidatively damaged DNA in Cockayne syndrome.
G. Fròsina
2007Free Radical Biology & Medicine22 citations
Semantic Scholar
Augmentation of 5-Aminolevulinic Acid Treatment of Glioblastoma by Adding Ciprofloxacin, Deferiprone, 5-Fluorouracil and Febuxostat: The CAALA Regimen
R. Kast, Nicolas Skuli, I. Sardi, F. Capanni +5 more
2018Brain Science21 citations Open access
Semantic Scholar
Frontiers in targeting glioma stem cells.
G. Fròsina
2011European Journal of Cancer21 citations
Semantic Scholar
Survival of high grade glioma patients depends on their age at diagnosis
G. Casartelli, A. Dorcaratto, J. Ravetti, S. Sola +3 more
2009Cancer Biology & Therapy21 citations Open access
Semantic Scholar
Reduced ligation during DNA base excision repair supported by BRCA2 mutant cells
M. Bogliolo, Richard M. Taylor, K. Caldecott, G. Fròsina
2000Oncogene20 citations
Semantic Scholar
Radiotherapy of High-grade Gliomas: Dealing With A Stalemate.
G. Fròsina
2023Critical reviews in oncology/hematology19 citations
Semantic Scholar
The efficacy and toxicity of ATM inhibition in glioblastoma initiating cells-driven tumor models.
G. Fròsina, D. Marubbi, D. Marcello, D. Vecchio +1 more
2019Critical reviews in oncology/hematology19 citations
Semantic Scholar
Prophylaxis of oxidative DNA damage by formamidopyrimidine‐DNA glycosylase
G. Fròsina
2006International Journal of Cancer19 citations Open access
Semantic Scholar
Analysis of repair of abasic sites in early onset breast cancer patients
O. Rossi, F. Carrozzino, E. Cappelli, Franca Carli +1 more
2000International Journal of Cancer19 citations Open access
Semantic Scholar
Radiotherapy of High-Grade Gliomas: First Half of 2021 Update with Special Reference to Radiosensitization Studies
G. Fròsina
2021International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
In vitro base excision repair assay using mammalian cell extracts.
G. Fròsina, E. Cappelli, M. Ropolo, P. Fortini +2 more
2006Methods in molecular biology17 citations
Semantic Scholar
Development of therapeutics for high grade gliomas using orthotopic rodent models.
G. Fròsina
2013Current Medicinal Chemistry15 citations
Semantic Scholar
Advances in drug delivery to high grade gliomas
G. Fròsina
2016Brain Pathology14 citations Open access
Semantic Scholar
Positron emission tomography of high-grade gliomas
G. Fròsina
2016Journal of Neuro-Oncology14 citations
Semantic Scholar
Defective repair of 5-hydroxy-2'-deoxycytidine in Cockayne syndrome cells and its complementation by Escherichia coli formamidopyrimidine DNA glycosylase and endonuclease III.
Mara Foresta, M. Ropolo, P. Degan, I. Pettinati +4 more
2010Free Radical Biology & Medicine14 citations
Semantic Scholar
Drosophila S3 ribosomal protein accelerates repair of 8‐oxoguanine performed by human and mouse cell extracts
E. Cappelli, A. D'Osualdo, M. Bogliolo, M. Kelley +1 more
2003Environmental and Molecular Mutagenesis14 citations
Semantic Scholar
Population structure of eastern Sicily.
Maria Beretta, P. Mazzetti, G. Fròsina, G. Schiliro' +3 more
1986Human Heredity14 citations
Semantic Scholar
Targeting the Ataxia Telangiectasia Mutated Protein in Cancer Therapy.
D. Vecchio, G. Fròsina
2016Current Drug Targets13 citations
Semantic Scholar
Tumor suppression by DNA base excision repair.
G. Fròsina
2007Mini-Reviews in Medical Chemistry12 citations
Semantic Scholar
Accelerated repair and reduced mutagenicity of oxidative DNA damage in human bladder cells expressing the E. coli FPG protein
M. Ropolo, Alessandro Geroldi, P. Degan, V. Andreotti +5 more
2006International Journal of Cancer12 citations Open access
Semantic Scholar
The O6-methylguanine-DNA-methyltransferase activity of rat hepatoma cells is increased after a single exposure to alkylating agents.
G. Fròsina, F. Laval
1987Carcinogenesis11 citations
Semantic Scholar
Faithful animal modelling of human glioma by using primary initiating cells and its implications for radiosensitization therapy
G. Fròsina, J. Ravetti, R. Corvò, M. Fella +15 more
2018Scientific Reports10 citations Open access
Semantic Scholar
Accelerated Repair and Reduced Mutagenicity of DNA Damage Induced by Cigarette Smoke in Human Bronchial Cells Transfected with E.coli Formamidopyrimidine DNA Glycosylase
Mara Foresta, A. Izzotti, S. La Maestra, R. Micale +3 more
2014PLoS ONE10 citations Open access
Semantic Scholar
Time-course of spontaneous transformation of CD-1 mouse embryonic fibroblasts.
O. Rossi, O. Barbieri, G. Fròsina
2003Anticancer Research10 citations
Semantic Scholar
The glioblastoma problem: targeting by combined medicinal chemistry approaches.
G. Fròsina
2015Current Medicinal Chemistry9 citations
Semantic Scholar
Expression of the Drosophila melanogaster S3 ribosomal/repair protein in T24 human bladder cells.
M. Ropolo, Alessandro Geroldi, O. Rossi, P. Degan +3 more
2004Anticancer Research8 citations
Semantic Scholar
Improving control of high‐grade glioma by ultra‐hyper‐fractionated radiotherapy
G. Fròsina
2022Journal of Neuroscience Research7 citations
Semantic Scholar
Non-routine Tracers for PET Imaging of High-grade Glioma.
G. Fròsina
2016Anticancer Research7 citations
Semantic Scholar

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E. Cappelli×8
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E. Cappelli — researcher profile on SciRah
M. Ropolo×8
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A. Poggi×8
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D. Vecchio×7
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A. Daga — researcher profile on SciRah

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P. Degan — researcher profile on SciRah

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D. Marubbi — researcher profile on SciRah

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O. Rossi — researcher profile on SciRah

E. Dogliotti×4

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Mara Foresta×4

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Mara Foresta — researcher profile on SciRah

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A. Raso — researcher profile on SciRah

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J. Ravetti — researcher profile on SciRah