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K. Sugano · SciRah

Researcher profile · Semantic Scholar

K. Sugano

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K. Sugano — researcher profile on SciRah

h-index: 39
Works: 190
Citations: 5,188

Most-cited papers

Feasibility and utility of a panel testing for 114 cancer‐associated genes in a clinical setting: A hospital‐based study
K. Sunami, H. Ichikawa, T. Kubo, M. Kato +36 more
2019Cancer Science304 citations Open access
Semantic Scholar
Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls
Y. Momozawa, Y. Iwasaki, M. Parsons, Y. Kamatani +11 more
2018Nature Communications235 citations Open access
Semantic Scholar
Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants
Y. Momozawa, Rumi Sasai, Y. Usui, K. Shiraishi +21 more
2022JAMA Oncology189 citations Open access
Semantic Scholar
Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer.
Y. Usui, Y. Taniyama, Mikiko Endo, Y. Koyanagi +24 more
2023New England Journal of Medicine178 citations
Semantic Scholar
Germline Pathogenic Variants in 7636 Japanese Patients With Prostate Cancer and 12 366 Controls
Y. Momozawa, Y. Iwasaki, M. Hirata, Xiao-Xi Liu +9 more
2019Journal of the National Cancer Institute94 citations Open access
Semantic Scholar
Cross‐sectional analysis of germline BRCA1 and BRCA2 mutations in Japanese patients suspected to have hereditary breast/ovarian cancer
K. Sugano, Seigo Nakamura, J. Ando, S. Takayama +27 more
2008Cancer Science92 citations Open access
Semantic Scholar
siRNA‐mediated Knockdown of the Heme Synthesis and Degradation Pathways: Modulation of Treatment Effect of 5‐Aminolevulinic Acid‐based Photodynamic Therapy in Urothelial Cancer Cell Lines
M. Miyake, Masazumi Ishii, K. Kawashima, T. Kodama +3 more
2009Photochemistry and Photobiology86 citations
Semantic Scholar
Fibroblast growth factor receptor 3 mutation in voided urine is a useful diagnostic marker and significant indicator of tumor recurrence in non‐muscle invasive bladder cancer
M. Miyake, K. Sugano, H. Sugino, Kazuho Imai +12 more
2010Cancer Science80 citations Open access
Semantic Scholar
Mismatch repair deficiency commonly precedes adenoma formation in Lynch Syndrome-Associated colorectal tumorigenesis
S. Sekine, T. Mori, Reiko Ogawa, Masahiro Tanaka +9 more
2017Modern Pathology72 citations Open access
Semantic Scholar
1-tert-Butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino)-pyrido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a Selective Tyrosine Kinase Inhibitor of Fibroblast Growth Factor Receptor-3 (FGFR3), Inhibits Cell Proliferation of Bladder Cancer Carrying the FGFR3 Gene Mutation along with Up-Regu
M. Miyake, Masazumi Ishii, Naoki Koyama, K. Kawashima +5 more
2010Journal of Pharmacology and Experimental Therapeutics65 citations
Semantic Scholar
Genetic characterization of pancreatic cancer patients and prediction of carrier status of germline pathogenic variants in cancer-predisposing genes
Keijiro Mizukami, Y. Iwasaki, Eiryo Kawakami, M. Hirata +9 more
2020EBioMedicine59 citations Open access
Semantic Scholar
The Use of Olaparib (AZD2281) Potentiates SN-38 Cytotoxicity in Colon Cancer Cells by Indirect Inhibition of Rad51-Mediated Repair of DNA Double-Strand Breaks
Makiko Tahara, Takeshi Inoue, F. Sato, Y. Miyakura +5 more
2014Molecular Cancer Therapeutics58 citations Open access
Semantic Scholar
Familial adenomatous polyposis‐associated and sporadic pyloric gland adenomas of the upper gastrointestinal tract share common genetic features
T. Hashimoto, Reiko Ogawa, Akiko Matsubara, H. Taniguchi +5 more
2015Histopathology54 citations
Semantic Scholar
Age- and Gender-Specific Risk of Thyroid Cancer in Patients With Familial Adenomatous Polyposis.
S. Uchino, H. Ishikawa, A. Miyauchi, M. Hirokawa +6 more
2016Journal of Clinical Endocrinology and Metabolism45 citations
Semantic Scholar
Clinicopathological study of SDHB mutation-related pheochromocytoma and sympathetic paraganglioma.
N. Kimura, K. Takekoshi, A. Horii, R. Morimoto +16 more
2014Endocrine-Related Cancer45 citations Open access
Semantic Scholar
Diagnostic markers of urothelial cancer based on DNA methylation analysis
Y. Chihara, Y. Kanai, H. Fujimoto, K. Sugano +6 more
2013BMC Cancer43 citations Open access
Semantic Scholar
Lynch syndrome-associated endometrial carcinoma with MLH1 germline mutation and MLH1 promoter hypermethylation: a case report and literature review
T. Yokoyama, K. Takehara, Nao Sugimoto, Keika Kaneko +10 more
2018BMC Cancer39 citations Open access
Semantic Scholar
Sensitive detection of FGFR3 mutations in bladder cancer and urine sediments by peptide nucleic acid-mediated real-time PCR clamping.
M. Miyake, K. Sugano, K. Kawashima, H. Ichikawa +7 more
2007Biochemical and Biophysical Research Communications - BBRC36 citations
Semantic Scholar
Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Tatsuro Yamaguchi, Y. Furukawa, Yusuke Nakamura, N. Matsubara +11 more
2015Japanese Journal of Clinical Oncology34 citations Open access
Semantic Scholar
Atypical pituitary adenoma with MEN1 somatic mutation associated with abnormalities of DNA mismatch repair genes; MLH1 germline mutation and MSH6 somatic mutation.
Shinsuke Uraki, Hiroyuki Ariyasu, Asako Doi, H. Furuta +6 more
2017Endocrine journal33 citations Open access
Semantic Scholar
Intratumoral CD8+ Lymphocyte Infiltration as a Prognostic Factor and Its Relationship With Cyclooxygenase 2 Expression and Microsatellite Instability in Endometrial Cancer
T. Suemori, N. Susumu, T. Iwata, K. Banno +5 more
2015International Journal of Gynecologic Cancer33 citations Open access
Semantic Scholar
Cell diameter measurements obtained with a handheld cell counter could be used as a surrogate marker of G2/M arrest and apoptosis in colon cancer cell lines exposed to SN-38.
Makiko Tahara, Takeshi Inoue, Y. Miyakura, H. Horie +4 more
2013Biochemical and Biophysical Research Communications - BBRC32 citations
Semantic Scholar
Reduced Expression of Mismatch Repair Genes MSH6/MSH2 Directly Promotes Pituitary Tumor Growth via the ATR–Chk1 Pathway
Shinsuke Uraki, Hiroyuki Ariyasu, Asako Doi, Shintaro Kawai +11 more
2018Journal of Clinical Endocrinology and Metabolism31 citations
Semantic Scholar
Impact of recent parity on histopathological tumor features and breast cancer outcome in premenopausal Japanese women
A. Nagatsuma, C. Shimizu, F. Takahashi, H. Tsuda +6 more
2013Breast Cancer Research and Treatment30 citations
Semantic Scholar
Genetic alterations in bladder cancer and their clinical applications in molecular tumor staging
K. Sugano, T. Kakizoe
2006Nature Clinical Practice Urology30 citations
Semantic Scholar
Haplotype defined by the MLH1-93G/A polymorphism is associated with MLH1 promoter hypermethylation in sporadic colorectal cancers
Y. Miyakura, Makiko Tahara, A. Lefor, Y. Yasuda +1 more
2014BMC Research Notes25 citations Open access
Semantic Scholar
Molecular epidemiological and mutational analysis of DNA mismatch repair (MMR) genes in endometrial cancer patients with HNPCC‐associated familial predisposition to cancer
Y. Hirai, K. Banno, Mitsuaki Suzuki, Y. Ichikawa +3 more
2008Cancer Science23 citations Open access
Semantic Scholar
Gastric cancer is highly prevalent in Lynch syndrome patients with atrophic gastritis
Hourin Cho, M. Yamada, S. Sekine, N. Tanabe +10 more
2020Gastric Cancer21 citations Open access
Semantic Scholar
Alcohol consumption and early-onset risk of colorectal cancer in Japanese patients with Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum
M. Miguchi, T. Hinoi, K. Tanakaya, Tatsuro Yamaguchi +13 more
2018Surgery today (Print)20 citations
Semantic Scholar
Cytoplasmic MSH2 immunoreactivity in a patient with Lynch syndrome with an EPCAM–MSH2 fusion
S. Sekine, Reiko Ogawa, S. Saito, M. Ushiama +6 more
2017Histopathology20 citations
Semantic Scholar
TP53 variants in p53 signatures and the clonality of STICs in RRSO samples
Tomoko Akahane, K. Masuda, Akira Hirasawa, Yusuke Kobayashi +15 more
2022Journal of Gynecologic Oncology18 citations Open access
Semantic Scholar
Mismatch repair deficiency in Lynch syndrome‐associated colorectal adenomas is more prevalent in older patients
Masahiro Tanaka, T. Nakajima, K. Sugano, T. Yoshida +4 more
2016Histopathology16 citations
Semantic Scholar
Identification of somatic APC mutations in recurrent desmoid tumors in a patient with familial adenomatous polyposis to determine actual recurrence of the original tumor or de novo occurrence
T. Iwama, Kouki Kuwabara, M. Ushiama, T. Yoshida +2 more
2008Familial Cancer16 citations Open access
Semantic Scholar
Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome
K. Yamaguchi, Rika Kasajima, Kiyoko Takane, Seira Hatakeyama +20 more
2021Journal of Human Genetics15 citations
Semantic Scholar
Experience of risk-reducing salpingo-oophorectomy for a BRCA1 mutation carrier and establishment of a system performing a preventive surgery for hereditary breast and ovarian cancer syndrome in Japan: our challenges for the future.
A. Hirasawa, K. Masuda, Tomoko Akahane, T. Tsuruta +8 more
2013Japanese Journal of Clinical Oncology15 citations Open access
Semantic Scholar
Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay
H. Naruse, Noriko Ikawa, K. Yamaguchi, Yusuke Nakamura +9 more
2009Familial Cancer15 citations
Semantic Scholar
Association between germline pathogenic variants in cancer‐predisposing genes and lymphoma risk
Y. Usui, Y. Iwasaki, K. Matsuo, Mikiko Endo +9 more
2022Cancer Science14 citations Open access
Semantic Scholar
Correction: Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients
T. Ikenoue, M. Arai, C. Ishioka, T. Iwama +15 more
2020Journal of Human Genetics13 citations Open access
Semantic Scholar
Mutation analysis of MUTYH in Japanese colorectal adenomatous polyposis patients
K. Taki, Yuri Sato, Sachio Nomura, Yuumi Ashihara +4 more
2016Familial Cancer13 citations
Semantic Scholar
Germline PMS2 mutation screened by mismatch repair protein immunohistochemistry of colorectal cancer in Japan
K. Sugano, T. Nakajima, S. Sekine, H. Taniguchi +5 more
2016Cancer Science13 citations Open access
Semantic Scholar
Detection of APC gene deletion by double competitive polymerase chain reaction in patients with familial adenomatous polyposis.
Maho Takahashi, Mariko Kikuchi, N. Ohkura, Hiroko Yaguchi +8 more
2006International Journal of Oncology13 citations Open access
Semantic Scholar
Causes of Cancer Death Among First-Degree Relatives in Japanese Families with Lynch Syndrome.
K. Tanakaya, Tatsuro Yamaguchi, H. Ishikawa, T. Hinoi +14 more
2016Anticancer Research12 citations
Semantic Scholar
Early detection of metachronous bile duct cancer in Lynch syndrome: report of a case
K. Shigeyasu, K. Tanakaya, T. Nagasaka, H. Aoki +8 more
2013Surgery today (Print)12 citations Open access
Semantic Scholar
Different risk genes contribute to clear cell and non-clear cell renal cell carcinoma in 1532 Japanese patients and 5996 controls.
Y. Sekine, Y. Iwasaki, T. Aoi, Mikiko Endo +14 more
2022Human Molecular Genetics11 citations Open access
Semantic Scholar
Solid-pseudopapillary neoplasm of the pancreas in a patient with familial adenomatous polyposis: a case report
Daishi Naoi, Koji Koinuma, Hideki Sasanuma, Y. Sakuma +6 more
2021Surgery Case Reports11 citations Open access
Semantic Scholar
Clinical characteristics of pancreatic and biliary tract cancers associated with Lynch syndrome
S. Takamizawa, C. Morizane, N. Tanabe, Y. Maruki +6 more
2021Journal of hepato-biliary-pancreatic sciences11 citations Open access
Semantic Scholar
Real-world outcome of universal screening for Lynch syndrome in Japanese patients with colorectal cancer highlights the importance of targeting patients with young-onset disease.
Atsushi Yamada, Yui Matsuoka, S. Minamiguchi, Yoshihiro Yamamoto +11 more
2021Molecular and clinical oncology11 citations Open access
Semantic Scholar
Germline mutations in cancer-predisposition genes in patients with biliary tract cancer
T. Terashima, K. Umemoto, Hideaki Takahashi, H. Hosoi +14 more
2019OncoTarget11 citations Open access
Semantic Scholar
MLH1 germline mutation associated with Lynch syndrome in a family followed for more than 45 years
T. Momma, Kenji Gonda, Yoshinori Akama, E. Endo +11 more
2019BMC Medical Genetics11 citations Open access
Semantic Scholar
Family history and BRCA1/BRCA2 status among Japanese ovarian cancer patients and occult cancer in a BRCA1 mutant case.
A. Hirasawa, K. Masuda, Tomoko Akahane, Arisa Ueki +12 more
2014Japanese Journal of Clinical Oncology11 citations Open access
Semantic Scholar

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