S. Loffredo

Most-cited papers

Are Mast Cells MASTers in Cancer?
G. Varricchi, M. Galdiero, S. Loffredo, Giancarlo Marone +3 more
2017Frontiers in Immunology304 citations Open access
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Mutation of the angiopoietin‐1 gene (ANGPT1) associates with a new type of hereditary angioedema
V. Bafunno, D. Firinu, M. d'Apolito, G. Cordisco +8 more
2017Journal of Allergy and Clinical Immunology268 citations Open access
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Eosinophils: The unsung heroes in cancer?
G. Varricchi, M. Galdiero, S. Loffredo, V. Lucarini +4 more
2018Oncoimmunology248 citations Open access
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VEGF-A in Cardiomyocytes and Heart Diseases
Mariantonia Braile, Simone Marcella, Leonardo Cristinziano, M. Galdiero +5 more
2020International Journal of Molecular Sciences212 citations Open access
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Angiogenesis and lymphangiogenesis in inflammatory skin disorders.
G. Varricchi, F. Granata, S. Loffredo, A. Genovese +1 more
2015Journal of American Academy of Dermatology167 citations
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The Intriguing Role of Interleukin 13 in the Pathophysiology of Asthma
G. Marone, F. Granata, V. Pucino, A. Pecoraro +4 more
2019Frontiers in Pharmacology150 citations Open access
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Roles of neutrophils in cancer growth and progression
M. Galdiero, G. Varricchi, S. Loffredo, A. Mantovani +1 more
2017Journal of Leukocyte Biology135 citations Open access
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Mast cells and basophils in inflammatory and tumor angiogenesis and lymphangiogenesis.
G. Marone, G. Varricchi, S. Loffredo, F. Granata
2016European Journal of Pharmacology127 citations
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A myoferlin gain‐of‐function variant associates with a new type of hereditary angioedema
A. Ariano, M. d'Apolito, M. Bova, F. Bellanti +8 more
2020Allergy. European Journal of Allergy and Clinical Immunology116 citations
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Human lung‐resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors
R. I. Staiano, S. Loffredo, F. Borriello, F. Iannotti +11 more
2016Journal of Leukocyte Biology116 citations Open access
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Neutrophil Extracellular Traps, Angiogenesis and Cancer
R. Poto, Leonardo Cristinziano, Luca Modestino, A. de Paulis +4 more
2022Biomedicines111 citations Open access
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Innate effector cells in angiogenesis and lymphangiogenesis.
G. Varricchi, S. Loffredo, M. Galdiero, G. Marone +3 more
2018Current Opinion in Immunology105 citations
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Heterogeneity of Human Mast Cells With Respect to MRGPRX2 Receptor Expression and Function
G. Varricchi, A. Pecoraro, S. Loffredo, R. Poto +4 more
2019Frontiers in Cellular Neuroscience103 citations Open access
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The Immune Landscape of Thyroid Cancer in the Context of Immune Checkpoint Inhibition
G. Varricchi, S. Loffredo, G. Marone, Luca Modestino +5 more
2019International Journal of Molecular Sciences96 citations Open access
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Tezepelumab: a novel biological therapy for the treatment of severe uncontrolled asthma
G. Marone, G. Spadaro, Mariantonia Braile, R. Poto +5 more
2019Expert Opinion on Investigational Drugs94 citations
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Anaplastic Thyroid Cancer Cells Induce the Release of Mitochondrial Extracellular DNA Traps by Viable Neutrophils
Leonardo Cristinziano, Luca Modestino, S. Loffredo, G. Varricchi +6 more
2020Journal of Immunology84 citations Open access
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Potential involvement of neutrophils in human thyroid cancer
M. Galdiero, G. Varricchi, S. Loffredo, Claudio Bellevicine +9 more
2018PLoS ONE81 citations Open access
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Group V Secreted Phospholipase A2 Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils
S. Loffredo, F. Borriello, R. Iannone, A. L. Ferrara +8 more
2017Frontiers in Immunology71 citations Open access
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GM-CSF and IL-3 Modulate Human Monocyte TNF-α Production and Renewal in In Vitro Models of Trained Immunity
F. Borriello, R. Iannone, S. di Somma, S. Loffredo +6 more
2017Frontiers in Immunology70 citations Open access
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Elevated plasma levels of vascular permeability factors in C1 inhibitor‐deficient hereditary angioedema
S. Loffredo, M. Bova, C. Suffritti, Francesco Borriello +6 more
2016Allergy. European Journal of Allergy and Clinical Immunology63 citations
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Innate Immune Modulation by GM-CSF and IL-3 in Health and Disease
F. Borriello, M. Galdiero, G. Varricchi, S. Loffredo +2 more
2019International Journal of Molecular Sciences60 citations Open access
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Is There a Role for Basophils in Cancer?
G. Marone, J. Schroeder, F. Mattei, S. Loffredo +5 more
2020Frontiers in Immunology54 citations Open access
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The Interplay between the Immune and the Endocannabinoid Systems in Cancer
Mariantonia Braile, Simone Marcella, G. Marone, M. Galdiero +2 more
2021Cells49 citations Open access
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IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors
Leonardo Cristinziano, R. Poto, Gjada Criscuolo, A. L. Ferrara +7 more
2021Cells46 citations Open access
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Superantigenic Activation of Human Cardiac Mast Cells
G. Varricchi, S. Loffredo, F. Borriello, A. Pecoraro +4 more
2019International Journal of Molecular Sciences46 citations Open access
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IL-3 synergizes with basophil-derived IL-4 and IL-13 to promote the alternative activation of human monocytes
F. Borriello, M. Longo, R. Spinelli, A. Pecoraro +7 more
2015European Journal of Immunology46 citations Open access
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Epigenetics: An opportunity to shape innate and adaptive immune responses
Antonietta Liotti, A. L. Ferrara, S. Loffredo, M. Galdiero +12 more
2022Immunology44 citations Open access
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Angiogenesis, Lymphangiogenesis, and Inflammation in Chronic Obstructive Pulmonary Disease (COPD): Few Certainties and Many Outstanding Questions
R. Poto, S. Loffredo, Francesco Palestra, G. Marone +2 more
2022Cells44 citations Open access
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Reslizumab and Eosinophilic Asthma: One Step Closer to Precision Medicine?
G. Varricchi, G. Senna, S. Loffredo, D. Bagnasco +2 more
2017Frontiers in Immunology44 citations Open access
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Eosinophils in the Tumor Microenvironment.
F. Mattei, S. Andreone, G. Marone, A. Gambardella +3 more
2020Advances in Experimental Medicine and Biology43 citations
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Mutational Spectrum of the C1 Inhibitor Gene in a Cohort of Italian Patients with Hereditary Angioedema: Description of Nine Novel Mutations
V. Bafunno, M. Bova, S. Loffredo, C. Divella +5 more
2014Annals of Human Genetics40 citations
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LPS‐mediated neutrophil VEGF‐A release is modulated by cannabinoid receptor activation
Mariantonia Braile, Leonardo Cristinziano, Simone Marcella, G. Varricchi +7 more
2020Journal of Leukocyte Biology39 citations
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Human Lung-Resident Macrophages Express and Are Targets of Thymic Stromal Lymphopoietin in the Tumor Microenvironment
Mariantonia Braile, A. Fiorelli, D. Sorriento, R. D. Di Crescenzo +5 more
2021Cells38 citations Open access
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Basophils beyond allergic and parasitic diseases
R. Poto, S. Loffredo, G. Marone, Antonio di Salvatore +3 more
2023Frontiers in Immunology37 citations Open access
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Impaired control of the contact system in hereditary angioedema with normal C1‐inhibitor
M. Bova, C. Suffritti, V. Bafunno, S. Loffredo +12 more
2019Allergy. European Journal of Allergy and Clinical Immunology37 citations Open access
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Immune cells as a source and target of angiogenic and lymphangiogenic factors.
S. Loffredo, R. I. Staiano, F. Granata, A. Genovese +1 more
2014Chemical Immunology37 citations
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Anti-Tumorigenic Activities of IL-33: A Mechanistic Insight
S. Andreone, A. Gambardella, Jacopo Mancini, S. Loffredo +5 more
2020Frontiers in Immunology32 citations Open access
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Lipopolysaccharide-Elicited TSLPR Expression Enriches a Functionally Discrete Subset of Human CD14+ CD1c+ Monocytes
F. Borriello, R. Iannone, S. di Somma, V. Vastolo +11 more
2017Journal of Immunology31 citations Open access
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TSLP is localized in and released from human lung macrophages activated by T2-high and T2-low stimuli: relevance in asthma and COPD.
Luisa Canè, R. Poto, Francesco Palestra, Marinella Pirozzi +10 more
2024European journal of internal medicine29 citations Open access
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Angiopoietins, Vascular Endothelial Growth Factors and Secretory Phospholipase A2 in Ischemic and Non-Ischemic Heart Failure
G. Varricchi, S. Loffredo, L. Bencivenga, A. L. Ferrara +5 more
2020Journal of Clinical Medicine28 citations Open access
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Are Basophils and Mast Cells Masters in HIV Infection?
G. Marone, G. Varricchi, S. Loffredo, M. Galdiero +2 more
2016International Archives of Allergy and Immunology27 citations Open access
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Roles of Immune Cells in Hereditary Angioedema
A. L. Ferrara, Leonardo Cristinziano, A. Petraroli, M. Bova +8 more
2021Clinical reviews in allergy and immunology26 citations Open access
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Evaluation of vaccination safety in children with mastocytosis
R. Parente, V. Pucino, D. Magliacane, A. Petraroli +3 more
2017Pediatric Allergy and Immunology26 citations
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Innate Immune Cells in Melanoma: Implications for Immunotherapy
M. Trocchia, Annagioia Ventrici, Luca Modestino, Leonardo Cristinziano +8 more
2024International Journal of Molecular Sciences25 citations Open access
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Pulmonary Hypertension Phenotypes in Systemic Sclerosis: The Right Diagnosis for the Right Treatment
U. Attanasio, A. Cuomo, F. Pirozzi, S. Loffredo +8 more
2020International Journal of Molecular Sciences25 citations Open access
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Secreted Phospholipases A2 in Hereditary Angioedema With C1-Inhibitor Deficiency
S. Loffredo, A. L. Ferrara, M. Bova, F. Borriello +11 more
2018Frontiers in Immunology25 citations Open access
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Oxidative stress markers are increased in patients with mastocytosis
S. Gangemi, P. Minciullo, D. Magliacane, Salvatore Saitta +5 more
2015Allergy. European Journal of Allergy and Clinical Immunology24 citations
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Hereditary angioedema attack: what happens to vasoactive mediators?
A. L. Ferrara, M. Bova, A. Petraroli, N. Veszeli +8 more
2019International Immunopharmacology22 citations Open access
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Melanoma-derived soluble mediators modulate neutrophil biological properties and the release of neutrophil extracellular traps
Luca Modestino, Leonardo Cristinziano, M. Trocchia, Annagioia Ventrici +12 more
2023Cancer Immunology and Immunotherapy21 citations Open access
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Episodic Angioedema with Hypereosinophilia (Gleich’s Syndrome): A Case Report and Extensive Review of the Literature
I. Mormile, A. Petraroli, S. Loffredo, F. Rossi +5 more
2021Journal of Clinical Medicine21 citations Open access
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