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R. Salpini · SciRah

Researcher profile · Semantic Scholar

R. Salpini

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R. Salpini — researcher profile on SciRah

h-index: 26
Works: 202
Citations: 1,994

Most-cited papers

Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses
A. Artese, V. Svicher, G. Costa, R. Salpini +7 more
2020Drug resistance updates95 citations Open access
Semantic Scholar
Whole exome HBV DNA integration is independent of the intrahepatic HBV reservoir in HBeAg-negative chronic hepatitis B
V. Svicher, R. Salpini, L. Piermatteo, L. Carioti +11 more
2020Gut68 citations Open access
Semantic Scholar
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile
M. Alkhatib, R. Salpini, L. Carioti, F. Ambrosio +10 more
2022Microbiology spectrum56 citations Open access
Semantic Scholar
SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021
M. Alkhatib, V. Svicher, R. Salpini, F. Ambrosio +9 more
2021Microbiology spectrum45 citations Open access
Semantic Scholar
Hepatitis B virus DNA integration as a novel biomarker of hepatitis B virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis B virus cure
R. Salpini, S. D'Anna, Livia Benedetti, L. Piermatteo +3 more
2022Frontiers in Microbiology37 citations Open access
Semantic Scholar
Unexpected rise in the circulation of complex HBV variants enriched of HBsAg vaccine-escape mutations in HBV genotype-D: potential impact on HBsAg detection/quantification and vaccination strategies
L. Piermatteo, S. D'Anna, A. Bertoli, M. Bellocchi +20 more
2023Emerging Microbes and Infections20 citations Open access
Semantic Scholar
Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment.
L. Piermatteo, R. Scutari, Riccardo Chirichiello, M. Alkhatib +9 more
2021Methods19 citations Open access
Semantic Scholar
Identification of gp120 polymorphisms in HIV-1 B subtype potentially associated with resistance to fostemsavir.
Y. Bouba, G. Berno, L. Fabeni, L. Carioti +6 more
2020Journal of Antimicrobial Chemotherapy18 citations
Semantic Scholar
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach
I. Romeo, F. Ambrosio, G. Costa, A. Corona +10 more
2022Molecules16 citations Open access
Semantic Scholar
Long-Term SARS-CoV-2 Infection Associated with Viral Dissemination in Different Body Fluids Including Bile in Two Patients with Acute Cholecystitis
R. Scutari, L. Piermatteo, M. Manuelli, M. Iannetta +14 more
2020Life16 citations Open access
Semantic Scholar
Key mutations in the C-terminus of the HBV surface glycoprotein correlate with lower HBsAg levels in vivo, hinder HBsAg secretion in vitro and reduce HBsAg structural stability in the setting of HBeAg-negative chronic HBV genotype-D infection
R. Salpini, A. Battisti, L. Piermatteo, L. Carioti +30 more
2020Emerging Microbes and Infections16 citations Open access
Semantic Scholar
New Therapies and Strategies to Curb HIV Infections with a Focus on Macrophages and Reservoirs
Maria Marra, A. Catalano, M. Sinicropi, J. Ceramella +6 more
2024Viruses15 citations Open access
Semantic Scholar
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach
F. Ambrosio, G. Costa, I. Romeo, F. Esposito +9 more
2023Journal of Chemical Information and Modeling15 citations Open access
Semantic Scholar
New insights into hepatitis B virus lymphotropism: Implications for HBV-related lymphomagenesis
V. Svicher, R. Salpini, S. D'Anna, L. Piermatteo +3 more
2023Frontiers in Oncology15 citations Open access
Semantic Scholar
An Increase in the Levels of Middle Surface Antigen Characterizes Patients Developing HBV-Driven Liver Cancer Despite Prolonged Virological Suppression
G. Brancaccio, R. Salpini, L. Piermatteo, M. Surdo +10 more
2021Microorganisms15 citations Open access
Semantic Scholar
Crucial Role of Central Nervous System as a Viral Anatomical Compartment for HIV-1 Infection
A. Borrajo, V. Svicher, R. Salpini, M. Pellegrino +1 more
2021Microorganisms14 citations Open access
Semantic Scholar
A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition In Vitro
R. Salpini, L. Piermatteo, A. Battisti, L. Colagrossi +23 more
2020Viruses14 citations Open access
Semantic Scholar
Cryptic HBV Replicative Activity Is Frequently Revealed in Anti-HBc-Positive/HBsAg-Negative Patients with HIV Infection by Highly Sensitive Molecular Assays, and Can Be Predicted by Integrating Classical and Novel Serological HBV Markers
R. Salpini, V. Malagnino, L. Piermatteo, T. Mulas +18 more
2020Microorganisms13 citations Open access
Semantic Scholar
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control
R. Salpini, M. Alkhatib, G. Costa, L. Piermatteo +10 more
2020Journal of Antimicrobial Chemotherapy13 citations Open access
Semantic Scholar
Kinetics of Hepatitis B Virus replication in anti-HBc positive/HBsAg-negative people with HIV switching to Tenofovir sparing therapy.
R. Salpini, S. D'Anna, M. Alkhatib, L. Piermatteo +13 more
2024International Journal of Infectious Diseases11 citations Open access
Semantic Scholar
SARS-CoV-2 Mutations and Variants May Muddle the Sensitivity of COVID-19 Diagnostic Assays
M. Alkhatib, L. Carioti, S. D'Anna, F. Ceccherini-Silberstein +2 more
2022Microorganisms11 citations Open access
Semantic Scholar
Insights into the Currently Available Drugs and Investigational Compounds Against RSV with a Focus on Their Drug-Resistance Profiles
A. Magnapera, Anna Riccio, Antonio Curcio, C. Tramontozzi +8 more
2025Viruses10 citations Open access
Semantic Scholar
Determinants of worse liver‐related outcome according to HDV infection among HBsAg positive persons living with HIV: Data from the ICONA cohort
Antonella d'Arminio Monforte, A. Tavelli, R. Salpini, L. Piermatteo +15 more
2023Liver international (Print)10 citations Open access
Semantic Scholar
Novel concepts on mechanisms underlying Hepatitis Delta virus persistence and related pathogenesis
R. Salpini, S. D'Anna, L. Piermatteo, V. Svicher
2022Journal of Viral Hepatitis10 citations
Semantic Scholar
Hepatitis B–Related Hepatic Flare During Immune Reconstitution Syndrome After Antiretroviral Treatment Initiation in an HBV Surface Antigen–Positive Patient With HIV: Viroimmunological and Histological Characterization
M. Iannetta, A. Crea, Andrea Di Lorenzo, L. Campogiani +15 more
2022Open Forum Infectious Diseases10 citations Open access
Semantic Scholar
Comparison of diagnostic performances of HDV-RNA quantification assays used in clinical practice: Results from a national quality control multicenter study.
R. Salpini, L. Piermatteo, G. Caviglia, A. Bertoli +64 more
2025Journal of Clinical Virology8 citations Open access
Semantic Scholar
HIV/HBV co-infection remodels the immune landscape and Natural Killer cell ADCC functional responses
Bo Sun, K. D. da Costa, Aljawharah Alrubayyi, J. Kokiçi +17 more
2024Hepatology8 citations Open access
Semantic Scholar
Poor CD4/CD8 ratio recovery in HBcAb-positive HIV patients with worse immune status is associated with significantly higher CD8 cell numbers
V. Malagnino, C. Cerva, E. Teti, L. Campogiani +10 more
2021Scientific Reports8 citations Open access
Semantic Scholar
HBcAb Positivity Is a Risk Factor for an Increased Detectability of HIV RNA after Switching to a Two-Drug Regimen Lamivudine-Based (2DR-3TC-Based) Treatment: Analysis of a Multicenter Italian Cohort
V. Malagnino, E. Teti, M. Compagno, L. Coppola +12 more
2021Microorganisms8 citations Open access
Semantic Scholar
Prevalence of HDV infection in Central Italy has remained stable across the last two decades with dominance of sub-genotypes 1 and characterized by elevated viral replication.
R. Salpini, L. Piermatteo, G. Torre, S. D'Anna +31 more
2023International Journal of Infectious Diseases7 citations Open access
Semantic Scholar
Role of HBcAb Positivity in Increase of HIV-RNA Detectability after Switching to a Two-Drug Regimen Lamivudine-Based (2DR-3TC-Based) Treatment: Months 48 Results of a Multicenter Italian Cohort
V. Malagnino, R. Salpini, E. Teti, M. Compagno +14 more
2023Viruses6 citations Open access
Semantic Scholar
Frequency of Atypical Mutations in the Spike Glycoprotein in SARS-CoV-2 Circulating from July 2020 to July 2022 in Central Italy: A Refined Analysis by Next Generation Sequencing
M. Bellocchi, R. Scutari, L. Carioti, M. Iannetta +17 more
2023Viruses5 citations Open access
Semantic Scholar
Highly Sensitive HBsAg, Anti-HBc and Anti HBsAg Titres in Early Diagnosis of HBV Reactivation in Anti-HBc-Positive Onco-Haematological Patients
C. Cerva, R. Salpini, M. Alkhatib, V. Malagnino +17 more
2022Biomedicines5 citations Open access
Semantic Scholar
HBeAg Levels Vary across the Different Stages of HBV Infection According to the Extent of Immunological Pressure and Are Associated with Therapeutic Outcome in the Setting of Immunosuppression-Driven HBV Reactivation
L. Piermatteo, M. Alkhatib, S. D'Anna, V. Malagnino +20 more
2021Biomedicines5 citations Open access
Semantic Scholar
HBsAg Isoforms as Innovative Biomarkers in Predicting Virological Response to Bulevirtide in Patients With Chronic Hepatitis D
S. D'Anna, R. Salpini, E. Degasperi, L. Piermatteo +8 more
2025Liver international (Print)4 citations
Semantic Scholar
Editorial: The current challenges underlying hepatitis D virus infection
R. Salpini, V. Svicher, Patrick T. F. Kennedy
2024Frontiers in Medicine3 citations Open access
Semantic Scholar
Direct Viral Mechanisms Underlying the Onset of HBV-Related Hepatocellular Carcinoma and Implications for Therapeutic Strategies
S. La Frazia, A. Magnapera, L. Piermatteo, S. D'Anna +3 more
2026Viruses2 citations
Semantic Scholar
HDV persistence acts independently from HBV reservoir extent and is sustained by HBsAg production mainly derived from integrated HBV-DNA
S. D'Anna, L. Piermatteo, G. Brancaccio, E. Teti +27 more
2025Digestive and Liver Disease2 citations
Semantic Scholar
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients
Carmen Gratteri, F. Ambrosio, A. Lupia, Federica Moraca +13 more
2023Pharmaceuticals2 citations Open access
Semantic Scholar
In the setting of HIV-infection, HBV-reactivation is revealed by highly sensitive assays in a conspicuous fraction of anti-HBc-positive/HBsAg-negative patients switching to Tenofovir-sparing therapy
R. Salpini, S. D'Anna, M. Alkhatib, L. Piermatteo +11 more
2022Journal of Hepatology2 citations
Semantic Scholar
Genetic Determinants in a Critical Domain of NS5A Correlate with Hepatocellular Carcinoma in Cirrhotic Patients Infected with HCV Genotype 1b
M. Alkhatib, V. D. di Maio, V. de Murtas, E. Polilli +25 more
2021Viruses2 citations Open access
Semantic Scholar
A peculiar composition of HBsAg isoforms characterizes chronic HDV coinfection respect to HBV mono-infection with higher middle- and large-HBs levels reflecting a more intense HDV activity
A. Magnapera, L. Piermatteo, S. D'Anna, A. Olivero +20 more
2025Digestive and Liver Disease1 citations
Semantic Scholar
OS-015 The burden of HDV chronic infection and the gaps in HDV screening across Europe: an urgent need to strengthen diagnostic strategies at pan-european level
R. Salpini, I. Alexiev, L. Baiocchi, L. Bănică +39 more
2025Journal of Hepatology1 citations
Semantic Scholar
Comparison of diagnostic performances of HDV RNA quantification assays used in clinical practice in Italy: data from the first national quality control multicenter study
L. Piermatteo, R. Salpini, G. Caviglia, A. Bertoli +41 more
2025Digestive and Liver Disease1 citations
Semantic Scholar
The transactivation of human endogenous retroviruses is associated with HIV-1 reservoir, lymphocyte activation and low CD4 count in virologically suppressed PLWH.
Vita Petrone, R. Scutari, V. Malagnino, L. Piermatteo +16 more
2025Microbes and infection1 citations Open access
Semantic Scholar
WED-399-YI The composition of HBsAg along with HDV-RNA predicts virological response in chronic hepatitis delta patients treated with bulevirtide for 48 weeks
S. D'Anna, R. Salpini, E. Degasperi, L. Duca +9 more
2024Journal of Hepatology1 citations
Semantic Scholar
FRI-392-YI Chronic HDV coinfection (CHD) is characterized by a more elevated production of Middle and Large HBsAg than HBV monoinfection, that parallels HDV replicative and cytolytic activity
L. Piermatteo, S. D'Anna, A. Olivero, L. Duca +19 more
2024Journal of Hepatology1 citations
Semantic Scholar
First National Prevalence in Italian Horse Population and Phylogenesis Highlight a Fourth Sub-Type Candidate of Equine Hepacivirus
R. Nardini, Giulia Pacchiarotti, V. Svicher, R. Salpini +8 more
2024Viruses1 citations Open access
Semantic Scholar
Pathways sustaining HDV activity act independently from the size of HBV resevoir and are fueled by an abundant expression of HBsAg from integrated HBV-DNA
R. Salpini, S. D'Anna, L. Piermatteo, E. Teti +23 more
2024Digestive and Liver Disease1 citations
Semantic Scholar
Stable temporal trend of HDV seroprevalence in central Italy across the last two decades with the circulation of HDV sub-genotypes 1 inducing different inflammatory stimuli
L. Piermatteo, R. Salpini, G. Torre, S. D'Anna +28 more
2023Journal of Hepatology1 citations
Semantic Scholar

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V. Svicher×46
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V. Svicher — researcher profile on SciRah
L. Piermatteo×36
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L. Piermatteo — researcher profile on SciRah
L. Sarmati×26
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L. Sarmati — researcher profile on SciRah
S. D'Anna×25
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S. D'Anna — researcher profile on SciRah

F. Ceccherini-Silberstein

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F. Ceccherini-Silberstein — researcher profile on SciRah

V. Malagnino×20

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V. Malagnino — researcher profile on SciRah

M. Alkhatib×15

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M. Alkhatib — researcher profile on SciRah

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E. Teti — researcher profile on SciRah

M. Andreoni×14

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M. Andreoni — researcher profile on SciRah

M. Iannetta×14

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M. Iannetta — researcher profile on SciRah

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A. Bertoli — researcher profile on SciRah

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L. Carioti — researcher profile on SciRah