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A. Rajakumar · SciRah

Researcher profile · Semantic Scholar

A. Rajakumar

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A. Rajakumar — researcher profile on SciRah

h-index: 34
Works: 88
Citations: 4,263

Most-cited papers

Zika Virus Infects Human Placental Macrophages
Kendra M. Quicke, James R. Bowen, Erica L. Johnson, C. McDonald +9 more
2016Cell Host and Microbe467 citations Open access
Semantic Scholar
Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor.
E. Shibata, A. Rajakumar, R. Powers, Robert W Larkin +6 more
2005Journal of Clinical Endocrinology and Metabolism261 citations
Semantic Scholar
Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae.
A. Rajakumar, H. Brandon, A. Daftary, Roberta B. Ness +1 more
2004Placenta254 citations
Semantic Scholar
Twin pregnancy and the risk of preeclampsia: bigger placenta or relative ischemia?
Y. Bdolah, Chun Lam, A. Rajakumar, Venkatesha Shivalingappa +6 more
2008American Journal of Obstetrics and Gynecology249 citations
Semantic Scholar
Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women.
A. Rajakumar, H. Michael, P. Rajakumar, E. Shibata +6 more
2005Placenta198 citations
Semantic Scholar
Expression, Ontogeny, and Regulation of Hypoxia-Inducible Transcription Factors in the Human Placenta1
A. Rajakumar, K. Conrad
2000Biology of Reproduction185 citations Open access
Semantic Scholar
Transcriptionally active syncytial aggregates in the maternal circulation may contribute to circulating sFlt1 in preeclampsia
A. Rajakumar, A. Cerdeira, S. Rana, Z. Zsengellér +6 more
2012HYPERTENSION170 citations Open access
Semantic Scholar
Angiotensin II Type 1 Receptor Antibodies and Increased Angiotensin II Sensitivity in Pregnant Rats
K. Wenzel, A. Rajakumar, H. Haase, N. Geusens +17 more
2011HYPERTENSION151 citations Open access
Semantic Scholar
Selective Overexpression of the Hypoxia-Inducible Transcription Factor, HIF-2α, in Placentas from Women with Preeclampsia
A. Rajakumar, Kerry A. Whitelock, L. Weissfeld, A. Daftary +2 more
2001148 citations
Semantic Scholar
Agonistic Angiotensin II Type 1 Receptor Autoantibodies in Postpartum Women With a History of Preeclampsia
C. Hubel, G. Wallukat, Myles Wolf, F. Herse +6 more
2007HYPERTENSION143 citations
Semantic Scholar
Relationships between maternal plasma leptin, placental leptin mRNA and protein in normal pregnancy, pre-eclampsia and intrauterine growth restriction without pre-eclampsia.
H. Laivuori, M. Gallaher, L. Collura, W. Crombleholme +5 more
2006Molecular human reproduction127 citations
Semantic Scholar
Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia.
S. Burke, Z. Zsengellér, E. Khankin, Agnes Lo +12 more
2016Journal of Clinical Investigation126 citations Open access
Semantic Scholar
Hydrogen sulfide producing enzymes in pregnancy and preeclampsia.
K. Holwerda, E. Bos, A. Rajakumar, C. Ris-Stalpers +6 more
2012Placenta90 citations Open access
Semantic Scholar
Vaccine-Derived Neutralizing Antibodies to the Human Cytomegalovirus gH/gL Pentamer Potently Block Primary Cytotrophoblast Infection
F. Chiuppesi, F. Wussow, Erica L. Johnson, C. Bian +6 more
2015Journal of Virology81 citations Open access
Semantic Scholar
Impaired Oxygen-dependent Reduction of HIF-1α and -2α Proteins in Pre-eclamptic Placentae
A. Rajakumar, K. Doty, A. Daftary, G. Harger +1 more
200380 citations
Semantic Scholar
Circulating and placental endoglin concentrations in pregnancies complicated by intrauterine growth restriction and preeclampsia.
Arun Jeyabalan, S. McGonigal, C. Gilmour, C. Hubel +1 more
2008Placenta78 citations Open access
Semantic Scholar
Leptin Affects System A Amino Acid Transport Activity in the Human Placenta: Evidence for STAT3 Dependent Mechanisms
F. von Versen-Höynck, A. Rajakumar, M. S. Parrott, R. Powers
2009Placenta77 citations Open access
Semantic Scholar
Increased Myeloperoxidase in the Placenta and Circulation of Women With Preeclampsia
R. Gandley, Jennifer Rohland, Yan Zhou, E. Shibata +5 more
2008HYPERTENSION71 citations Open access
Semantic Scholar
Novel Soluble Flt-1 Isoforms in Plasma and Cultured Placental Explants from Normotensive Pregnant and Preeclamptic Women
A. Rajakumar, R. Powers, C. Hubel, E. Shibata +3 more
2008Placenta71 citations Open access
Semantic Scholar
Preeclampsia and soluble fms-like tyrosine kinase 1.
J. Roberts, A. Rajakumar
2009Journal of Clinical Endocrinology and Metabolism61 citations Open access
Semantic Scholar
Human Placental Adenosine Receptor Expression is Elevated in Preeclampsia and Hypoxia Increases Expression of the A2A Receptor
F. von Versen-Höynck, A. Rajakumar, Shannon A. Bainbridge, M. Gallaher +2 more
2009Placenta60 citations Open access
Semantic Scholar
Trophoblast mitochondrial function is impaired in preeclampsia and correlates negatively with the expression of soluble fms-like tyrosine kinase 1.
Z. Zsengellér, A. Rajakumar, J. Hunter, S. Salahuddin +3 more
2016Pregnancy Hypertension59 citations
Semantic Scholar
FLT1 and transcriptome-wide polyadenylation site (PAS) analysis in preeclampsia
Ami Ashar-Patel, Yasin Kaymaz, A. Rajakumar, J. Bailey +2 more
2017Scientific Reports57 citations Open access
Semantic Scholar
Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins.
A. Rajakumar, H. Michael, A. Daftary, Arundhathi Jeyabalan +2 more
2008Placenta57 citations
Semantic Scholar
Relationship between hypoxia and downstream pathogenic pathways in preeclampsia
H. Korkes, L. D. de Oliveira, N. Sass, S. Salahuddin +2 more
2017Hypertension in Pregnancy54 citations Open access
Semantic Scholar
Angiotensin II decreases system A amino acid transporter activity in human placental villous fragments through AT1 receptor activation.
E. Shibata, R. Powers, A. Rajakumar, F. von Versen-Höynck +4 more
2006American Journal of Physiology. Endocrinology and Metabolism54 citations
Semantic Scholar
Maternal Gene Expression Profiling During Pregnancy And Preeclampsia In Human Peripheral Blood Mononuclear Cells
A. Rajakumar, Tianjiao Chu, D. Handley, K. Bunce +4 more
2010Placenta50 citations Open access
Semantic Scholar
Ouabain inhibits placental sFlt1 production by repressing HSP27‐dependent HIF‐1α pathway
S. Rana, A. Rajakumar, Carl Geahchan, S. Salahuddin +5 more
2014The FASEB Journal47 citations Open access
Semantic Scholar
Placental HIF-1α, HIF-2α, membrane and soluble VEGF receptor-1 proteins are not increased in normotensive pregnancies complicated by late-onset intrauterine growth restriction
A. Rajakumar, Arun Jeyabalan, N. Marković, R. Ness +2 more
200747 citations
Semantic Scholar
Drug Repurposing Screen Identifies Foxo1-Dependent Angiopoietin-2 Regulation in Sepsis
Chandra C. Ghosh, K. Thamm, Anthony V Berghelli, C. Schrimpf +15 more
2015Critical Care Medicine45 citations Open access
Semantic Scholar
Preeclampsia Is Associated With the Presence of Transcriptionally Active Placental Fragments in the Maternal Lung
Aletta J. Buurma, M. Penning, F. Prins, J. Schutte +6 more
2013HYPERTENSION44 citations
Semantic Scholar
Maternal Endothelial Progenitor Colony-Forming Units With Macrophage Characteristics Are Reduced in Preeclampsia
Carol Lin, A. Rajakumar, Daniel A. Plymire, Vivek Verma +2 more
2009American Journal of Hypertension44 citations Open access
Semantic Scholar
Trans-activators Regulating Neuronal Glucose Transporter Isoform-3 Gene Expression in Mammalian Neurons*
A. Rajakumar, S. Thamotharan, N. Raychaudhuri, R. Menon +1 more
2004Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Pharmacokinetics and Placental Transfer of Elvitegravir, Dolutegravir, and Other Antiretrovirals during Pregnancy
M. Badell, R. Chakraborty, B. Rimawi, Erica L. Johnson +6 more
2017Antimicrobial Agents and Chemotherapy39 citations Open access
Semantic Scholar
Placental HIF-1 alpha, HIF-2 alpha, membrane and soluble VEGF receptor-1 proteins are not increased in normotensive pregnancies complicated by late-onset intrauterine growth restriction.
A. Rajakumar, Arun Jeyabalan, N. Marković, R. Ness +2 more
2007American Journal of Physiology. Regulatory Integrative and Comparative Physiology34 citations
Semantic Scholar
Decidual cells from women with preeclampsia exhibit inadequate decidualization and reduced sFlt1 suppression.
Margaret B. Sahu, V. Deepak, S. K. Gonzales, B. Rimawi +5 more
2019Pregnancy Hypertension32 citations
Semantic Scholar
Organotin(IV) derivatives of amide-based carboxylates: Synthesis, spectroscopic characterization, single crystal studies and antimicrobial, antioxidant, cytotoxic, anti-leishmanial, hemolytic, noncancerous, anticancer activities
I. Ahmad, Zia-ur-Rehman, A. Waseem, M. Tariq +6 more
202028 citations
Semantic Scholar
Potency analysis of Mesenchymal Stromal Cells using a phospho-STAT matrix loop analytical approach
Raghavan Chinnadurai, A. Rajakumar, Andrew J Schneider, W. Bushman +2 more
2019Stem Cells26 citations Open access
Semantic Scholar
Associations Between the Features of Gross Placental Morphology and Birthweight
Alexa A. Freedman, C. Hogue, C. Marsit, A. Rajakumar +9 more
2018Pediatric and Developmental Pathology26 citations Open access
Semantic Scholar
Vascular pool of releasable soluble VEGF receptor-1 (sFLT1) in women with previous preeclampsia and uncomplicated pregnancy.
T. Weissgerber, A. Rajakumar, Ashley C. Myerski, L. Edmunds +4 more
2014Journal of Clinical Endocrinology and Metabolism26 citations Open access
Semantic Scholar
Human endometrial stromal cell plasticity: Reversible sFlt1 expression negatively coincides with decidualization
Hanh N. Cottrell, Juan-Juan Wu, B. Rimawi, J. Durán +3 more
2017Hypertension in Pregnancy25 citations
Semantic Scholar
Induced Human Decidual NK-Like Cells Improve Utero-Placental Perfusion in Mice
Ricardo C. Cavalli, A. Cerdeira, Elizabeth Pernicone, H. Korkes +7 more
2016PLoS ONE23 citations Open access
Semantic Scholar
Excess placental secreted frizzled-related protein 1 in maternal smokers impairs fetal growth.
Alice Wang, Z. Zsengellér, J. Hecht, R. Buccafusca +6 more
2015Journal of Clinical Investigation22 citations Open access
Semantic Scholar
Soluble fms-like tyrosine kinase-1 and soluble endoglin in HIV-associated preeclampsia.
N. Govender, T. Naicker, A. Rajakumar, J. Moodley
2013European Journal of Obstetrics, Gynecology, and Reproductive Biology21 citations
Semantic Scholar
Nitric Oxide Synthase Isoforms in the Rat Kidney During Pregnancy
J. Novak, A. Rajakumar, T. M. Miles, K. Conrad
2004Journal of the Society for Gynecologic Investigation21 citations
Semantic Scholar
Bioflavonoid luteolin prevents sFlt-1 release via HIF-1α inhibition in cultured human placenta
A. Eddy, Chun-Yi Chiang, A. Rajakumar, F. Spradley +3 more
2023The FASEB Journal19 citations Open access
Semantic Scholar
Selective Overexpression of the Hypoxia-Inducible Transcription Factor, HIF-2α, in Placentas from Women with Preeclampsia1
A. Rajakumar, Kerry A. Whitelock, L. Weissfeld, A. Daftary +2 more
2001Biology of Reproduction19 citations
Semantic Scholar
Retinoic Acid Is a Negative Regulator of sFLT1 Expression in Decidual Stromal Cells, and Its Levels Are Reduced in Preeclamptic Decidua
V. Deepak, Margaret B. Sahu, Jian-Shi Yu, Jace W. Jones +5 more
2019HYPERTENSION15 citations Open access
Semantic Scholar
Effects of Supraphysiologic Levels of Estradiol on Endometrial Decidualization, sFlt1, and HOXA10 Expression
Hanh N. Cottrell, V. Deepak, J. Spencer, N. Sidell +1 more
2019Reproductive Sciences15 citations
Semantic Scholar
Expression of von Hippel Lindau (pVHL) protein in placentae from normal pregnant women and women with preeclampsia.
A. Rajakumar, K. Doty, A. Daftary, Nina Markovic +1 more
2006Placenta15 citations
Semantic Scholar

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