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C. Seemayer · SciRah

Researcher profile · Semantic Scholar

C. Seemayer

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C. Seemayer — researcher profile on SciRah

h-index: 27
Works: 62
Citations: 3,023

Most-cited papers

Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis.
G. Palmer, D. Talabot‐Ayer, C. Lamacchia, Dean Y. Toy +5 more
2009Arthritis & Rheumatism328 citations Open access
Semantic Scholar
The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles.
J. Distler, A. Jüngel, L. Huber, C. Seemayer +7 more
2005Proceedings of the National Academy of Sciences of the United States of America285 citations Open access
Semantic Scholar
Galectin 3 and its binding protein in rheumatoid arthritis.
S. Ohshima, S. Kuchen, C. Seemayer, D. Kyburz +7 more
2003Arthritis & Rheumatism213 citations
Semantic Scholar
Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis.
A. Jüngel, J. Distler, M. Kurowska-Stolarska, C. Seemayer +7 more
2004Arthritis & Rheumatism187 citations
Semantic Scholar
C4d staining of renal allograft biopsies: a comparative analysis of different staining techniques.
C. Seemayer, A. Gaspert, V. Nickeleit, M. Mihatsch
2006Nephrology, Dialysis and Transplantation136 citations Open access
Semantic Scholar
Dexamethasone-containing PLGA superparamagnetic microparticles as carriers for the local treatment of arthritis.
Nicoleta Butoescu, C. Seemayer, Michelangelo Foti, O. Jordan +1 more
2009Biomaterials132 citations Open access
Semantic Scholar
Effect of particle size on the biodistribution of nano- and microparticles following intra-articular injection in mice.
J. Pradal, P. Maudens, C. Gabay, C. Seemayer +2 more
2016International journal of pharmaceutics120 citations Open access
Semantic Scholar
Trichostatin A sensitises rheumatoid arthritis synovial fibroblasts for TRAIL-induced apoptosis
A. Jüngel, V. Barešová, C. Ospelt, B. Simmen +5 more
2005Annals of the Rheumatic Diseases103 citations Open access
Semantic Scholar
[Lys40(Ahx-DTPA-111In)NH2]-Exendin-4 Is a Highly Efficient Radiotherapeutic for Glucagon-Like Peptide-1 Receptor–Targeted Therapy for Insulinoma
A. Wicki, D. Wild, Daniela Storch, C. Seemayer +7 more
2007Clinical Cancer Research99 citations Open access
Semantic Scholar
Functional characterization of adherent synovial fluid cells in rheumatoid arthritis: destructive potential in vitro and in vivo.
M. Neidhart, C. Seemayer, K. Hummel, B. Michel +2 more
2003Arthritis & Rheumatism94 citations
Semantic Scholar
FLICE-inhibitory protein expression in synovial fibroblasts and at sites of cartilage and bone erosion in rheumatoid arthritis.
J. Schedel, R. Gay, P. Kuenzler, C. Seemayer +3 more
2002Arthritis & Rheumatism94 citations
Semantic Scholar
Cartilage destruction mediated by synovial fibroblasts does not depend on proliferation in rheumatoid arthritis.
C. Seemayer, S. Kuchen, P. Kuenzler, V. Rihosková +7 more
2003American Journal of Pathology81 citations Open access
Semantic Scholar
Detection of synovial macrophages in an experimental rabbit model of antigen-induced arthritis: ultrasmall superparamagnetic iron oxide-enhanced MR imaging.
A. Lutz, C. Seemayer, C. Corot, R. Gay +5 more
2004Radiology80 citations
Semantic Scholar
Self-assembled thermoresponsive nanostructures of hyaluronic acid conjugates for osteoarthritis therapy.
P. Maudens, S. Meyer, C. Seemayer, O. Jordan +1 more
2018Nanoscale78 citations Open access
Semantic Scholar
Ribozymes that inhibit the production of matrix metalloproteinase 1 reduce the invasiveness of rheumatoid arthritis synovial fibroblasts.
E. Rutkauskaite, W. Zacharias, J. Schedel, U. Müller-Ladner +8 more
2004Arthritis & Rheumatism77 citations
Semantic Scholar
Close association between HER-2 amplification and overexpression in human tumors of non-breast origin
C. Tapia, K. Glatz, H. Novotny, A. Lugli +8 more
2007Modern Pathology76 citations Open access
Semantic Scholar
Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment.
P. Maudens, C. Seemayer, Cédric Thauvin, C. Gabay +2 more
2018Small74 citations Open access
Semantic Scholar
Nanocrystals of a potent p38 MAPK inhibitor embedded in microparticles: Therapeutic effects in inflammatory and mechanistic murine models of osteoarthritis
P. Maudens, C. Seemayer, François Pfefferlé, O. Jordan +1 more
2018Journal of Controlled Release68 citations Open access
Semantic Scholar
Enhanced Th1 and Th17 responses and arthritis severity in mice with a deficiency of myeloid cell-specific interleukin-1 receptor antagonist.
C. Lamacchia, G. Palmer, C. Seemayer, D. Talabot‐Ayer +1 more
2010Arthritis & Rheumatism61 citations Open access
Semantic Scholar
The severity of experimental arthritis is independent of IL-36 receptor signaling
C. Lamacchia, G. Palmer, E. Rodriguez, Praxedis Martin +5 more
2013Arthritis Research & Therapy57 citations Open access
Semantic Scholar
The L1 Retroelement-related p40 Protein Induces p38δ MAP Kinase
S. Kuchen, C. Seemayer, J. Rethage, Rebecca von Knoch +5 more
200456 citations
Semantic Scholar
Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice
Nicoleta Butoescu, C. Seemayer, G. Palmer, P. Guerne +3 more
2009Arthritis Research & Therapy47 citations Open access
Semantic Scholar
GLPG1205 for idiopathic pulmonary fibrosis: a phase 2 randomised placebo-controlled trial
I. Strâmbu, C. Seemayer, Liesbeth Fagard, P. Ford +9 more
2022European Respiratory Journal46 citations Open access
Semantic Scholar
Synovial tissues concentrate secreted APRIL
C. Gabay, V. Krenn, Carine Bosshard, C. Seemayer +2 more
2009Arthritis Research & Therapy41 citations Open access
Semantic Scholar
Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency
Praxedis Martin, D. Talabot‐Ayer, C. Seemayer, S. Vigne +6 more
2013Arthritis Research & Therapy38 citations Open access
Semantic Scholar
Adeno-associated virus type 5-mediated intraarticular administration of tumor necrosis factor small interfering RNA improves collagen-induced arthritis.
Maroun Khoury, G. Courties, S. Fabre, C. Bouffi +5 more
2010Arthritis & Rheumatism38 citations
Semantic Scholar
Severe Neutrophil-Dominated Inflammation and Enhanced Myelopoiesis in IL-33–Overexpressing CMV/IL33 Mice
D. Talabot‐Ayer, Praxedis Martin, C. Vesin, C. Seemayer +3 more
2015Journal of Immunology30 citations Open access
Semantic Scholar
BK virus large T and VP-1 expression in infected human renal allografts
C. Seemayer, N. Seemayer, U. Dürmüller, F. Gudat +3 more
2008Nephrology, Dialysis and Transplantation27 citations Open access
Semantic Scholar
Protein level expression of Toll-like receptors 2, 4 and 9 in renal disease.
S. Batsford, U. Duermueller, C. Seemayer, C. Mueller +2 more
2011Nephrology, Dialysis and Transplantation25 citations Open access
Semantic Scholar
Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells.
J. Niven, N. Madelon, N. Page, Assunta Caruso +5 more
2019Cell Reports23 citations Open access
Semantic Scholar
Intra-articular bioactivity of a p38 MAPK inhibitor and development of an extended-release system.
J. Pradal, María-Fernanda Zuluaga, P. Maudens, Jean-Marc Waldburger +5 more
2015European journal of pharmaceutics and biopharmaceutics23 citations Open access
Semantic Scholar
Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory Responses
Praxedis Martin, G. Palmer, E. Rodriguez, C. Seemayer +3 more
2017Journal of Immunology22 citations Open access
Semantic Scholar
Results of a phase 2 study of GLPG1205 for idiopathic pulmonary fibrosis (PINTA)
V. Cottin, C. Seemayer, Liesbeth Fagard, P. Ford +7 more
2021Idiopathic interstitial pneumonias21 citations
Semantic Scholar
Immune-mediated experimental arthritis in IL-33 deficient mice.
D. Talabot‐Ayer, Praxedis Martin, C. Seemayer, S. Vigne +5 more
2014Cytokine18 citations Open access
Semantic Scholar
The L1 retroelement-related p40 protein induces p38delta MAP kinase.
S. Kuchen, C. Seemayer, J. Rethage, Rebecca von Knoch +5 more
2004Autoimmunity17 citations
Semantic Scholar
Mice deficient in hepatocyte‐specific IL‐1Ra show delayed resolution of concanavalin A‐induced hepatitis
C. Lamacchia, E. Rodriguez, G. Palmer, C. Vesin +3 more
2012European Journal of Immunology16 citations Open access
Semantic Scholar
Articular inflammation is controlled by myeloid cell-derived interleukin 1 receptor antagonist during the acute phase of arthritis in mice
C. Lamacchia, E. Rodriguez, G. Palmer, S. Vigne +4 more
2011Annals of the Rheumatic Diseases16 citations Open access
Semantic Scholar
Low prevalence of SV40 in Swiss mesothelioma patients after elimination of false-positive PCR results.
A. Ziegler, C. Seemayer, M. Hinterberger, P. Vogt +6 more
2007Lung Cancer16 citations Open access
Semantic Scholar
Modeling the Effect of the Selective S1P1 Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes
Dominik Lott, Andreas Krause, C. Seemayer, D. Strasser +2 more
2016Pharmaceutical Research11 citations
Semantic Scholar
Trichostatin-A sensitizes rheumatoid arthritis synovial fibroblasts for TRAIL-induced apoptosis
A. Jüngel, Veronika Baresova, C. Ospelt, B. Simmen +5 more
200510 citations
Semantic Scholar
Absence of inducible retroviruses from synovial fibroblasts and synovial fluid cells of patients with rheumatoid arthritis.
C. Seemayer, S. Kolb, M. Neidhart, S. Ohshima +5 more
2002Arthritis & Rheumatism9 citations
Semantic Scholar
Induction of p16 at sites of cartilage invasion in the SCID mouse coimplantation model of rheumatoid arthritis.
P. Kuenzler, S. Kuchen, V. Rihosková, B. Michel +4 more
2003Arthritis & Rheumatism8 citations
Semantic Scholar
Autoimmunity and inflammation are independent of class II transactivator type PIV-dependent class II major histocompatibility complex expression in peripheral tissues during collagen-induced arthritis.
Jean-Marc Waldburger, G. Palmer, C. Seemayer, C. Lamacchia +5 more
2011Arthritis & Rheumatism7 citations Open access
Semantic Scholar
Incidence and tumour stages of breast cancer in the region of Aachen, Germany.
C. Seemayer, E. Breuer, G. Kroll, S. Markus-Sellhaus +2 more
2002European Journal of Cancer Care6 citations Open access
Semantic Scholar
No indications of an enhanced UV-light-induced unscheduled DNA synthesis in splenocytes of mice following a low-dose irradiation in vivo or in vitro
Andrzej Wojcik, C. Seemayer, Wolfgang-Ulrich Müller, C. Streffer
1995Radiation and Environmental Biophysics6 citations
Semantic Scholar
Synovial fibroblasts in joint destruction of rheumatoid arthritis
C. Seemayer, M. Neidhart, A. Jüngel
20055 citations
Semantic Scholar
Structure-Activity Relationship Guided Scaffold Hopping Resulted in the Identification of GLPG4970, a Highly Potent Dual SIK2/SIK3 Inhibitor.
H. Kelgtermans, M. De Wachter, Stijn Heyndrickx, Sandy El Bkassiny +42 more
2025Journal of Medicinal Chemistry2 citations
Semantic Scholar
Lys 40 ( Ahx-DTPA-111 In ) NH 2 ]-Exendin-4 Is a Highly Efficient Radiotherapeutic for Glucagon-Like Peptide-1 Receptor ^ TargetedTherapy for
AndreasWicki, DamianWild, Daniela Storch, C. Seemayer +6 more
20071 citations
Semantic Scholar
In situ hybridization of synovial tissue.
S. Kuchen, C. Seemayer, M. Neidhart, R. Gay +1 more
2007Methods in Molecular Medicine1 citations
Semantic Scholar
Idiopathic pulmonary fibrosis (IPF): observations from a Phase 2 trial of GLPG1205 (PINTA)
I. Strâmbu, Liesbeth Fagard, P. Ford, T. Van Der Aa +3 more
2020Idiopathic interstitial pneumonias0 citations
Semantic Scholar

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