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Laura Bettinetti · SciRah

Researcher profile · Semantic Scholar

Laura Bettinetti

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Laura Bettinetti — researcher profile on SciRah

h-index: 11
Works: 18
Citations: 558

Most-cited papers

Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists.
Laura Bettinetti, Karin Schlotter, H. Hübner, P. Gmeiner
2002Journal of Medicinal Chemistry168 citations Open access
Semantic Scholar
Dopamine D2, D3, and D4 selective phenylpiperazines as molecular probes to explore the origins of subtype specific receptor binding.
Katharina Ehrlich, Angela Götz, Stefan Bollinger, Nuska Tschammer +5 more
2009Journal of Medicinal Chemistry87 citations Open access
Semantic Scholar
Arnica montana Stimulates Extracellular Matrix Gene Expression in a Macrophage Cell Line Differentiated to Wound-Healing Phenotype
M. Marzotto, Clara Bonafini, D. Olioso, A. Baruzzi +4 more
2016PLoS ONE54 citations Open access
Semantic Scholar
Parallel synthesis and biological screening of dopamine receptor ligands taking advantage of a click chemistry based BAL linker.
Laura Bettinetti, S. Löber, H. Hübner, P. Gmeiner
2005Journal of combinatorial chemistry51 citations
Semantic Scholar
Transcriptomic Profiling Discloses Molecular and Cellular Events Related to Neuronal Differentiation in SH-SY5Y Neuroblastoma Cells
F. Pezzini, Laura Bettinetti, F. di Leva, M. Bianchi +6 more
2017Cellular and molecular neurobiology49 citations Open access
Semantic Scholar
SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist.
S. Haydar, C. Ghiron, Laura Bettinetti, Hendrick Bothmann +11 more
2009Bioorganic & Medicinal Chemistry42 citations Open access
Semantic Scholar
Discovery of a novel alpha-7 nicotinic acetylcholine receptor agonist series and characterization of the potent, selective, and orally efficacious agonist 5-(4-acetyl[1,4]diazepan-1-yl)pentanoic acid [5-(4-methoxyphenyl)-1H-pyrazol-3-yl] amide (SEN15924, WAY-361789).
R. Zanaletti, Laura Bettinetti, C. Castaldo, Giuseppe Cocconcelli +12 more
2012Journal of Medicinal Chemistry30 citations Open access
Semantic Scholar
Analogs of the dopamine D4 receptor ligand FAUC 113 with planar- and central-chirality
S. Löber, Birgit Ortner, Laura Bettinetti, H. Hübner +1 more
200217 citations
Semantic Scholar
Attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity by the novel selective dopamine D3-receptor partial agonist FAUC 329 predominantly in the nucleus accumbens of mice.
F. Boeckler, Andreas Leng, A. Mura, Laura Bettinetti +3 more
2003Biochemical Pharmacology16 citations
Semantic Scholar
Novel Hits in the Correction of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3-d]pyrimidines for the Potential Treatment of Cystic Fibrosis.
Elisabetta Pesci, Laura Bettinetti, P. Fanti, Luis J. V. Galietta +5 more
2015Journal of Medicinal Chemistry15 citations Open access
Semantic Scholar
N-[5-(5-fluoropyridin-3-yl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): a medicinal chemistry effort toward an α7 nicotinic acetylcholine receptor agonist preclinical candidate.
R. Zanaletti, Laura Bettinetti, C. Castaldo, I. Ceccarelli +14 more
2012Journal of Medicinal Chemistry14 citations Open access
Semantic Scholar
Fused 3-Hydroxy-3-trifluoromethylpyrazoles Inhibit Mutant Huntingtin Toxicity.
S. La Rosa, T. Benicchi, Laura Bettinetti, I. Ceccarelli +12 more
2013ACS Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
Transcriptomic Profiling Discloses Molecular and Cellular Events Related to Neuronal Differentiation in SH-SY5Y Neuroblastoma Cells
F. Pezzini, Laura Bettinetti, Francesca Di Leva, M. Bianchi +6 more
2016Cellular and molecular neurobiology4 citations Open access
Semantic Scholar
Chirospecific and Subtype Selective Dopamine Receptor Binding of Heterocyclic Methoxynaphthamide Analogs
Laura Bettinetti, H. Hübner, P. Gmeiner
2005Archiv der Pharmazie3 citations
Semantic Scholar
Drug Discovery by Targeting Protein–Protein Interactions
Laura Bettinetti, Matteo Magnani, A. Padova
20131 citations
Semantic Scholar
Impaired neuronal connectivity as dysregulated cellular function in CLN1 disease: A pathogenetic prediction by RNAseq analysis
A. Simonati, F. Pezzini, M. Bianchi, Laura Bettinetti +4 more
20170 citations
Semantic Scholar
Corrigendum to “SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist” [Bioorg. Med. Chem. 17 (2009) 5247]
S. Haydar, C. Ghiron, Laura Bettinetti, Hendrick Bothmann +11 more
20100 citations Open access
Semantic Scholar
Carboxamides of indolizins and its aza and diazaderivate
P. Gmeiner, H. Huebner, Laura Bettinetti, Karin Schlotter
20050 citations
Semantic Scholar

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P. Gmeiner×7
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P. Gmeiner — researcher profile on SciRah
H. Hübner×5
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C. Scali×5
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Michela Valacchi×5
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S. Haydar — researcher profile on SciRah

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C. Ghiron — researcher profile on SciRah

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T. Comery — researcher profile on SciRah

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J. Dunlop — researcher profile on SciRah

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S. La Rosa — researcher profile on SciRah

Iolanda Micco×4

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Iolanda Micco — researcher profile on SciRah

R. Zanaletti×4

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R. Zanaletti — researcher profile on SciRah

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F. Pezzini — researcher profile on SciRah