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I. Irrcher · SciRah

Researcher profile · Semantic Scholar

I. Irrcher

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I. Irrcher — researcher profile on SciRah

h-index: 22
Works: 45
Citations: 3,279

Most-cited papers

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.
I. Irrcher, H. Aleyasin, E. Seifert, S. Hewitt +19 more
2010Human Molecular Genetics422 citations Open access
Semantic Scholar
Interactions between ROS and AMP kinase activity in the regulation of PGC-1alpha transcription in skeletal muscle cells.
I. Irrcher, Vladimir Ljubicic, D. Hood
2009American Journal of Physiology - Cell Physiology391 citations
Semantic Scholar
Coordination of metabolic plasticity in skeletal muscle
D. Hood, I. Irrcher, Vladimir Ljubicic, Anna-Maria Joseph
2006Journal of Experimental Biology391 citations Open access
Semantic Scholar
PPARγ coactivator-1α expression during thyroid hormone-and contractile activity-induced mitochondrial adaptations
I. Irrcher, Peter J. Adhihetty, Treacey E. Sheehan, Anna-Maria Joseph +1 more
2003319 citations
Semantic Scholar
Regulation of Mitochondrial Biogenesis in Muscle by Endurance Exercise
I. Irrcher, Peter J. Adhihetty, Anna-Maria Joseph, Vladimir Ljubicic +1 more
2003Sports Medicine223 citations
Semantic Scholar
AMP-Activated Protein Kinase-Regulated Activation of the PGC-1α Promoter in Skeletal Muscle Cells
I. Irrcher, Vladimir Ljubicic, Angie F. Kirwan, D. Hood
2006PLoS ONE198 citations Open access
Semantic Scholar
Plasticity of Skeletal Muscle Mitochondria in Response to Contractile Activity
Peter J. Adhihetty, I. Irrcher, Anna-Maria Joseph, Vladimir Ljubicic +1 more
2003Experimental Physiology175 citations
Semantic Scholar
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway
H. Aleyasin, Maxime W. C. Rousseaux, Paul C. Marcogliese, S. Hewitt +9 more
2010Proceedings of the National Academy of Sciences of the United States of America174 citations Open access
Semantic Scholar
PPARgamma coactivator-1alpha expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations.
I. Irrcher, Peter J. Adhihetty, T. Sheehan, Anna-Maria Joseph +1 more
2003American Journal of Physiology - Cell Physiology137 citations
Semantic Scholar
Safety and Tolerability of Acetazolamide in the Idiopathic Intracranial Hypertension Treatment Trial
M. T. ten Hove, D. Friedman, Anil D. Patel, I. Irrcher +2 more
2016Journal of neuro-ophthalmology84 citations Open access
Semantic Scholar
CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.
Arezu Jahani-Asl, E. Huang, I. Irrcher, J. Rashidian +4 more
2015Human Molecular Genetics81 citations Open access
Semantic Scholar
Multiple signaling pathways regulate contractile activity‐mediated PGC‐1α gene expression and activity in skeletal muscle cells
Yuan Zhang, Giulia Uguccioni, Vladimir Ljubicic, I. Irrcher +4 more
2014Physiological Reports75 citations Open access
Semantic Scholar
Contractile Activity-induced Transcriptional Activation of Cytochrome c Involves Sp1 and Is Proportional to Mitochondrial ATP Synthesis in C2C12 Muscle Cells*
M. Connor, I. Irrcher, D. Hood
2001Journal of Biological Chemistry75 citations Open access
Semantic Scholar
Thyroid hormone (T3) rapidly activates p38 and AMPK in skeletal muscle in vivo.
I. Irrcher, Donald R. Walkinshaw, Treacey E. Sheehan, D. Hood
2008Journal of applied physiology72 citations
Semantic Scholar
Calcium-regulated changes in mitochondrial phenotype in skeletal muscle cells.
D. Freyssenet, I. Irrcher, M. Connor, Martino Di Carlo +1 more
2004American Journal of Physiology - Cell Physiology65 citations
Semantic Scholar
Mitochondrial biogenesis and the role of the protein import pathway.
D. Hood, Peter J. Adhihetty, Marco Colavecchia, J. Gordon +4 more
2003Medicine & Science in Sports & Exercise58 citations Open access
Semantic Scholar
Regulation of the VHL/HIF-1 Pathway by DJ-1
M. Parsanejad, Yi Zhang, Dianbo Qu, I. Irrcher +9 more
2014Journal of Neuroscience51 citations Open access
Semantic Scholar
Regulation of Egr-1, SRF, and Sp1 mRNA expression in contracting skeletal muscle cells.
I. Irrcher, D. Hood
2004Journal of applied physiology47 citations
Semantic Scholar
DJ-1 Interacts with and Regulates Paraoxonase-2, an Enzyme Critical for Neuronal Survival in Response to Oxidative Stress
M. Parsanejad, N. Bourquard, Dianbo Qu, Yi Zhang +12 more
2014PLoS ONE45 citations Open access
Semantic Scholar
Anti-inflammatory therapy after selective laser trabeculoplasty: a randomized, double-masked, placebo-controlled clinical trial.
Delan Jinapriya, M. D'souza, H. Hollands, S. El-Defrawy +8 more
2014Ophthalmology (Rochester, Minn.)40 citations
Semantic Scholar
Local oral and nasal microbiome diversity in age-related macular degeneration
J. Rullo, P. M. Far, M. Quinn, N. Sharma +3 more
2020Scientific Reports30 citations Open access
Semantic Scholar
Parkinson’s Disease: To Live or Die by Autophagy
I. Irrcher, David S. Park
2009Science Signaling23 citations
Semantic Scholar
A Method of Evaluating Helmet Rotational Acceleration Protection Using the Kingston Impact Simulator (KIS Unit)
M. Kis, Fraser W. Saunders, I. Irrcher, Charles Tator +2 more
2013Clinical Journal of Sports Medicine18 citations
Semantic Scholar
Assessing a narrated white board animation as part of the consent process for intravenous fluorescein angiography: a randomized educational study.
Z. Mednick, I. Irrcher, W. Hopman, Sanjay Sharma
2016Canadian Journal of Ophthalmology-journal Canadien D Ophtalmologie17 citations
Semantic Scholar
Intraocular Calcidiol: Uncovering a role for vitamin D in the eye.
J. Rullo, Tracie Pennimpede, P. M. Far, Y. N. Strube +9 more
2019Journal of Steroid Biochemistry and Molecular Biology11 citations
Semantic Scholar
Validation of the visual acuity iPad app Eye Chart Pro compared to the standard Early Treatment Diabetic Retinopathy Study chart in a low-vision population
Hassan Hazari, Rachel Curtis, Karen Eden, W. Hopman +2 more
2020Journal of Telemedicine and Telecare10 citations
Semantic Scholar
Thyroid hormone ( T 3 ) rapidly activates p 38 and AMPK in skeletal muscle in vivo
I. Irrcher, Donald R. Walkinshaw, Treacey E. Sheehan, D. Hood
200810 citations
Semantic Scholar
Validation of a portable, remotely delivered refraction approach compared to standard in-clinic refraction in a low-vision population
Rachel Curtis, Hassan Hazari, Karen Eden, W. Hopman +2 more
2020Journal of Telemedicine and Telecare9 citations
Semantic Scholar
CDK 5 phosphorylates DRP 1 and drives mitochondrial defects in NMDA-induced neuronal death
Arezu Jahani-Asl, E. Huang, I. Irrcher, J. Rashidian +4 more
20157 citations
Semantic Scholar
Anaesthetic plus dilating gel improves pupil dilation for cataract surgery.
Delan Jinapriya, David R. P. Almeida, Davin E. Johnson, I. Irrcher +1 more
2012Canadian Journal of Ophthalmology-journal Canadien D Ophtalmologie7 citations
Semantic Scholar
Smartphone Compatible versus Conventional Ophthalmoscope: A Randomized Crossover Educational Trial
Rachel Curtis, Mark Xu, Daisy Liu, Jason Kwok +3 more
2021Journal of Academic Ophthalmology5 citations Open access
Semantic Scholar
Advances in Teleophthalmology
I. Irrcher, M. T. ten Hove
2019Advances in Ophthalmology and Optometry4 citations
Semantic Scholar
Measuring intraocular antibodies in eyes treated with anti-vascular endothelial growth factor.
J. Rullo, Steven S. Bae, P. M. Far, Amro Al Hazimi +9 more
2020Canadian Journal of Ophthalmology-journal Canadien D Ophtalmologie2 citations
Semantic Scholar
Refractive Status In Patients With Narrow Angles
Sarah M. Simpson, D. Warder, A. Moore, I. Irrcher +1 more
20121 citations
Semantic Scholar
Modern Day Application of Trans Scleral Diode Laser Achieving Good Intraocular Pressure Control with Acceptable Risk Profile
P. Crichton, I. Irrcher, Delan Jinapriya
20160 citations
Semantic Scholar
Randomized Clinical Trial Evaluating Reflux, IOP, and Pain, Following Intravitreal Anti Vascular Endothelial Growth Factors Injections Using 30g and 32g Needles
Saeed T Alshahrani, Vasudha Gupta, Uriel Rubin, Tom Gonder +2 more
20160 citations
Semantic Scholar
Refractive Profile of a Canadian Narrow Angle Population: a Prospective, Consecutive Enrollment Study
E. B. Moss, Sarah M. Simpson, H. Singh, I. Irrcher +1 more
20160 citations
Semantic Scholar
Identification of vascular endothelial growth factor protein in eyelid basal cell carcinomas: A potential novel, non-surgical therapy
C. Law, Ashley Minuk, I. Irrcher, J. Farmer +1 more
20140 citations
Semantic Scholar
Systemic absorption of bevacizumab after subcutaneous eyelid skin injection: an animal study.
V. Kratky, Ashley Minuk, C. Law, I. Irrcher
20140 citations
Semantic Scholar
Tissue‐specific regulation of cell signaling by acute thyroid hormone treatment in vivo
Donald R. Walkinshaw, I. Irrcher, D. A. Hood
20060 citations
Semantic Scholar
Review Coordination of metabolic plasticity in skeletal muscle
D. Hood, I. Irrcher, Vladimir Ljubicic, Anna-Maria Joseph
20060 citations
Semantic Scholar
SIGNALING PATHWAYS AND PGC-1 PROTEIN EXPRESSION IN T3- AND CONTRACTILE ACTIVITY-INDUCED MITOCHONDRIAL BIOGENESIS
I. Irrcher, Peter J. Adhihetty, T. Sheehan, Anna-Maria Joseph +1 more
20030 citations
Semantic Scholar
MICROARRAY ANALYSIS OF GENE EXPRESSION IN CONTRACTING SKELETAL MUSCLE CELLS.
I. Irrcher, J. Gonçalves, J. Paris, D. Hood +1 more
20020 citations
Semantic Scholar
INTEGRIN SIGNALING DOES NOT MEDIATE THE INCREASE IN ZIF268 MRNA DURING CONTRACTILE ACTIVITY
S. T. Lowe, I. Irrcher, L. Nunes, D. Hood
20010 citations
Semantic Scholar
TRANSCRIPTION FACTORS WHICH BIND TO GC-RICH REGIONS ARE IMPORTANT IN MUSCLE MITOCHONDRIAL BIOGENESIS
I. Irrcher, L. Nunes, D. Freyssenet, M. Connor +1 more
20010 citations Open access
Semantic Scholar

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