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A. Pozzi · SciRah

Researcher profile · Semantic Scholar

A. Pozzi

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A. Pozzi — researcher profile on SciRah

h-index: 58
Works: 236
Citations: 11K

Most-cited papers

The nature and biology of basement membranes
A. Pozzi, P. Yurchenco, R. Iozzo
2016Matrix Biology510 citations Open access
Semantic Scholar
Discoidin Domain Receptors in Disease
C. Borza, A. Pozzi
2013Matrix Biology193 citations Open access
Semantic Scholar
Progression of chronic kidney disease: too much cellular talk causes damage
L. Gewin, R. Zent, A. Pozzi
2016Kidney International149 citations Open access
Semantic Scholar
Integrins in kidney disease.
A. Pozzi, R. Zent
2013Journal of the American Society of Nephrology119 citations Open access
Semantic Scholar
Discoidin domain receptor 1 (DDR1) kinase as target for structure-based drug discovery
S. Kothiwale, C. Borza, W. Lowe, A. Pozzi +1 more
2014Drug Discovery Today82 citations Open access
Semantic Scholar
Deleting the TGF-β receptor attenuates acute proximal tubule injury.
L. Gewin, Sangeetha Vadivelu, Surekha Neelisetty, M. Srichai +4 more
2012Journal of the American Society of Nephrology77 citations Open access
Semantic Scholar
Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding
Rachel B. Reinert, Qing Cai, Ji-young Hong, Jennifer L. Plank +10 more
2014Development76 citations Open access
Semantic Scholar
Techniques and assays for the study of angiogenesis
Michael W. Irvin, A. Zijlstra, J. Wikswo, A. Pozzi
2014Experimental biology and medicine71 citations Open access
Semantic Scholar
Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling.
Xiwu Chen, Hongtao Wang, Hong-Jun Liao, Wen Hu +9 more
2014Journal of Clinical Investigation69 citations Open access
Semantic Scholar
Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells
Charles G. Miller, A. Pozzi, R. Zent, J. Schwarzbauer
2014Molecular Biology of the Cell69 citations Open access
Semantic Scholar
Extracellular chloride signals collagen IV network assembly during basement membrane formation
Christopher F. Cummings, V. Pedchenko, K. Brown, Selene Colon +15 more
2016Journal of Cell Biology68 citations Open access
Semantic Scholar
Inhibition of integrin α2β1 ameliorates glomerular injury.
C. Borza, Yan Su, Xiwu Chen, Ling Yu +11 more
2012Journal of the American Society of Nephrology59 citations Open access
Semantic Scholar
DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3
C. Borza, Gema Bolás, F. Bock, Xiuqi Zhang +11 more
2021JCI Insight56 citations Open access
Semantic Scholar
PPARα activation can help prevent and treat non-small cell lung cancer
Nataliya I. Skrypnyk, Xiwu Chen, Wen Hu, Yan Su +9 more
2013Cancer Research56 citations Open access
Semantic Scholar
β1 integrin regulates adult lung alveolar epithelial cell inflammation.
E. Plosa, J. Benjamin, J. M. Sucre, Peter M. Gulleman +10 more
2019JCI Insight53 citations Open access
Semantic Scholar
Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.
M. Gangadhariah, J. M. Luther, V. Garcia, P. Paueksakon +10 more
2015Journal of the American Society of Nephrology52 citations Open access
Semantic Scholar
p47phox contributes to albuminuria and kidney fibrosis in mice
Hongtao Wang, Xiwu Chen, Yan Su, P. Paueksakon +6 more
2015Kidney International52 citations Open access
Semantic Scholar
Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening
Wenjun Wang, Lauren A. Hapach, Lauren A. Griggs, Kyra Smart +9 more
2022Science Advances51 citations Open access
Semantic Scholar
Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis
C. Borza, Yan Su, Truc‐Linh Tran, Ling Yu +9 more
2016Matrix Biology50 citations Open access
Semantic Scholar
Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development
Bertha C. Elias, Amrita Das, D. Parekh, G. Mernaugh +7 more
2015Journal of Cell Science50 citations Open access
Semantic Scholar
Cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids contribute to insulin sensitivity in mice and in humans
M. Gangadhariah, Blake W. Dieckmann, L. Lantier, Kang-Fan Li +11 more
2017Diabetologia47 citations Open access
Semantic Scholar
Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice
L. Kang, S. Mokshagundam, B. Reuter, D. Lark +8 more
2016Diabetes42 citations Open access
Semantic Scholar
The Extracellular Matrix Receptor Discoidin Domain Receptor 1 Regulates Collagen Transcription by Translocating to the Nucleus.
M. Chiusa, Wen Hu, Hong-Jun Liao, Yan Su +12 more
2019Journal of the American Society of Nephrology41 citations Open access
Semantic Scholar
The cytochrome P450 slow metabolizers CYP2C9*2 and CYP2C9*3 directly regulate tumorigenesis via reduced epoxyeicosatrienoic acid production
Lindsay N Sausville, M. Gangadhariah, M. Chiusa, S. Mei +9 more
2018Cancer Research40 citations Open access
Semantic Scholar
Integrin α1β1 participates in Chondrocyte Transduction of Osmotic Stress.
C. Jablonski, S. Ferguson, A. Pozzi, A. Clark
2014Biochemical and Biophysical Research Communications - BBRC40 citations Open access
Semantic Scholar
The Integrin β1 Subunit Regulates Paracellular Permeability of Kidney Proximal Tubule Cells*
Bertha C. Elias, Sijo Mathew, M. Srichai, Riya J. Palamuttam +7 more
2014Journal of Biological Chemistry39 citations Open access
Semantic Scholar
The laminin binding α3 and α6 integrins cooperate to promote epithelial cell adhesion and growth
E. Yazlovitskaya, Olga M. Viquez, T. Tu, A. De Arcangelis +4 more
2018Matrix Biology38 citations Open access
Semantic Scholar
Integrating integrins with the hallmarks of cancer
S. Haake, B. Ríos, A. Pozzi, R. Zent
2024Matrix Biology37 citations Open access
Semantic Scholar
Integrin α1-null Mice Exhibit Improved Fatty Liver When Fed a High Fat Diet Despite Severe Hepatic Insulin Resistance*
Ashley S. Williams, L. Kang, Jenny-Yue Zheng, Carrie A. Grueter +4 more
2015Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation
K. Taguchi, Bertha C. Elias, Sho Sugahara, Snehal Sant +7 more
2022Journal of Clinical Investigation36 citations Open access
Semantic Scholar
The Role of the EGF Receptor in Sex Differences in Kidney Injury.
Ming-Zhi Zhang, K. Sasaki, Yan Li, Zhi-Lian Li +12 more
2019Journal of the American Society of Nephrology36 citations Open access
Semantic Scholar
Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice
P. Luo, A. Dematteo, Z. Wang, L. Zhu +5 more
2013Diabetologia35 citations Open access
Semantic Scholar
Cytochrome P450 epoxygenases and cancer: A genetic and a molecular perspective
Lindsay N Sausville, Scott M. Williams, A. Pozzi
2019Pharmacology and Therapeutics31 citations
Semantic Scholar
Integrin α1β1 protects against signs of post-traumatic osteoarthritis in the female murine knee partially via regulation of epidermal growth factor receptor signalling.
S. Y. Shin, A. Pozzi, S. K. Boyd, A. Clark
2016Osteoarthritis and Cartilage30 citations Open access
Semantic Scholar
Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance
Ashley S. Williams, Elijah Trefts, L. Lantier, Carrie A. Grueter +5 more
2016Diabetes30 citations Open access
Semantic Scholar
Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function
Zhenwei Lu, Sijo Mathew, Jiang Chen, Arina Hadziselimovic +6 more
2016eLife29 citations Open access
Semantic Scholar
THE ROLE OF CELL-EXTRACELLULAR MATRIX INTERACTIONS IN GLOMERULAR INJURY
C. Borza, A. Pozzi
2012Experimental Cell Research29 citations Open access
Semantic Scholar
Discovery of VU6015929: A Selective Discoidin Domain Receptor 1/2 (DDR1/2) Inhibitor to Explore the Role of DDR1 in Antifibrotic Therapy.
Daniel E. Jeffries, C. Borza, A. L. Blobaum, A. Pozzi +1 more
2019ACS Medicinal Chemistry Letters26 citations Open access
Semantic Scholar
Sulfenylation of Human Liver and Kidney Microsomal Cytochromes P450 and Other Drug-Metabolizing Enzymes as a Response to Redox Alteration *
M. Albertolle, Thanh T. N. Phan, A. Pozzi, F. Guengerich
2018Molecular & Cellular Proteomics26 citations Open access
Semantic Scholar
Heme–thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition
Matthew E. Albertolle, Donghak Kim, Leslie D. Nagy, Chul-Ho Yun +4 more
2017Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt
E. Yazlovitskaya, Hui-yuan Tseng, Olga M. Viquez, T. Tu +11 more
2015Molecular Biology of the Cell25 citations Open access
Semantic Scholar
Enhancing Integrin α1 Inserted (I) Domain Affinity to Ligand Potentiates Integrin α1β1-mediated Down-regulation of Collagen Synthesis*
Mingjian Shi, V. Pedchenko, Briana H. Greer, W. D. Van Horn +6 more
2012Journal of Biological Chemistry25 citations Open access
Semantic Scholar
The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation
C. Borza, Gema Bolás, Xiuqi Zhang, Mary Beth Browning Monroe +15 more
2022Frontiers in Cell and Developmental Biology23 citations Open access
Semantic Scholar
EGF receptor–mediated FUS phosphorylation promotes its nuclear translocation and fibrotic signaling
M. Chiusa, Wen Hu, J. Zienkiewicz, Xiwu Chen +13 more
2020Journal of Cell Biology23 citations Open access
Semantic Scholar
Salt-bridge modulates differential calcium-mediated ligand binding to integrin α1- and α2-I domains
K. Brown, Surajit Banerjee, Andrew Feigley, H. Abe +4 more
2018Scientific Reports23 citations Open access
Semantic Scholar
Integrin alpha6 maintains the structural integrity of the kidney collecting system
Olga M. Viquez, E. Yazlovitskaya, T. Tu, G. Mernaugh +10 more
2016Matrix Biology23 citations Open access
Semantic Scholar
Cell Receptor-Basement Membrane Interactions in Health and Disease: a Kidney-Centric View
C. Borza, Xiwu Chen, R. Zent, A. Pozzi
2015Current topics in membranes21 citations Open access
Semantic Scholar
Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury
Qiong-Hong Xie, M. Zhang, Xiaoyi Mao, Mingyue Xu +9 more
2022Cell Death and Disease20 citations Open access
Semantic Scholar
Ligand-independent integrin β1 signaling supports lung adenocarcinoma development
S. Haake, E. Plosa, J. Kropski, L. Venton +19 more
2022JCI Insight18 citations Open access
Semantic Scholar
CD98 Increases Renal Epithelial Cell Proliferation by Activating MAPKs
N. Bulus, C. Féral, A. Pozzi, R. Zent
2012PLoS ONE18 citations Open access
Semantic Scholar

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