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W. Kutschke · SciRah

Researcher profile · Semantic Scholar

W. Kutschke

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W. Kutschke — researcher profile on SciRah

h-index: 33
Works: 68
Citations: 5,769

Most-cited papers

A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation.
Jeffrey R. Erickson, M. Joiner, Xiaoqun Guan, W. Kutschke +15 more
2008Cell1,119 citations Open access
Semantic Scholar
Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo
C. Antos, T. McKinsey, N. Frey, W. Kutschke +5 more
2002Proceedings of the National Academy of Sciences of the United States of America460 citations Open access
Semantic Scholar
T-tubule remodeling during transition from hypertrophy to heart failure
Sheng Wei, A. Guo, Bi-Yi Chen, W. Kutschke +6 more
2010Circulation Research397 citations Open access
Semantic Scholar
Cardiac hypertrophy is not a required compensatory response to short-term pressure overload.
J. Hill, Mohsen Karimi, W. Kutschke, R. Davisson +4 more
2000Circulation337 citations Open access
Semantic Scholar
Oxidation of CaMKII determines cardiotoxic effects of aldosterone
B. J. He, M. Joiner, Madhu V. Singh, Elizabeth D. Luczak +15 more
2011Nature Medicine267 citations Open access
Semantic Scholar
Diabetes increases mortality after myocardial infarction by oxidizing CaMKII.
M. Luo, Xiaoqun Guan, Elizabeth D. Luczak, D. Lang +13 more
2013Journal of Clinical Investigation250 citations Open access
Semantic Scholar
Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo.
C. Antos, T. McKinsey, N. Frey, W. Kutschke +5 more
2002Proceedings of the National Academy of Sciences of the United States of America235 citations
Semantic Scholar
Oxidized CaMKII causes cardiac sinus node dysfunction in mice.
P. Swaminathan, Anil Purohit, S. Soni, Niels Voigt +18 more
2011Journal of Clinical Investigation226 citations Open access
Semantic Scholar
Calmodulin kinase II is required for fight or flight sinoatrial node physiology
Yue-Jin Wu, Zhan Gao, Bi-Yi Chen, Olha M. Koval +10 more
2009Proceedings of the National Academy of Sciences of the United States of America167 citations Open access
Semantic Scholar
Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart
Tyler P. Rasmussen, Yue-Jin Wu, M. Joiner, Olha M. Koval +20 more
2015Proceedings of the National Academy of Sciences of the United States of America165 citations Open access
Semantic Scholar
Targeted Inhibition of Calcineurin in Pressure-overload Cardiac Hypertrophy
Joseph A. Hill, B. Rothermel, K. Yoo, B. Cabuay +5 more
2002Journal of Biological Chemistry133 citations Open access
Semantic Scholar
MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction.
Madhu V. Singh, P. Swaminathan, Elizabeth D. Luczak, W. Kutschke +2 more
2012Journal of Molecular and Cellular Cardiology128 citations Open access
Semantic Scholar
Microtubule-Mediated Defects in Junctophilin-2 Trafficking Contribute to Myocyte T-Tubule Remodeling and Ca2+ Handling Dysfunction in Heart Failure
Caimei Zhang, Bi-Yi Chen, A. Guo, Yanqi Zhu +12 more
2014Circulation127 citations Open access
Semantic Scholar
Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart.
Madhu V. Singh, A. Kapoun, L. Higgins, W. Kutschke +12 more
2009Journal of Clinical Investigation119 citations Open access
Semantic Scholar
RGS6, a Modulator of Parasympathetic Activation in Heart
Jian-Qi Yang, Jie Huang, B. Maity, Zhan Gao +13 more
2010Circulation Research118 citations Open access
Semantic Scholar
Mitochondrial Pyruvate Carriers are Required for Myocardial Stress Adaptation
Yuan Zhang, Paul V. Taufalele, J. Cochran, I. Frayne +26 more
2020Nature Metabolism115 citations Open access
Semantic Scholar
Critical roles of junctophilin-2 in T-tubule and excitation-contraction coupling maturation during postnatal development.
Bi-Yi Chen, A. Guo, Caimei Zhang, Rong Chen +9 more
2013Cardiovascular Research106 citations Open access
Semantic Scholar
Chronic Tempol Prevents Hypertension, Proteinuria, and Poor Feto-Placental Outcomes in BPH/5 Mouse Model of Preeclampsia
Darren S. Hoffmann, Christine J. Weydert, E. Lazartigues, W. Kutschke +5 more
2008HYPERTENSION95 citations Open access
Semantic Scholar
Na+-Ca2+ Exchanger Remodeling in Pressure Overload Cardiac Hypertrophy*
Zhengyi Wang, Bridgid Nolan, W. Kutschke, Joseph A. Hill
2001Journal of Biological Chemistry94 citations Open access
Semantic Scholar
Overexpression of junctophilin-2 does not enhance baseline function but attenuates heart failure development after cardiac stress
A. Guo, Xiao-Ying Zhang, V. Iyer, Bi-Yi Chen +5 more
2014Proceedings of the National Academy of Sciences of the United States of America91 citations Open access
Semantic Scholar
Electrical Remodeling in Pressure-Overload Cardiac Hypertrophy: Role of Calcineurin
Zheng-Yi Wang, W. Kutschke, K. Richardson, Mohsen Karimi +1 more
2001Circulation80 citations
Semantic Scholar
β‐Adrenergic receptor antagonists ameliorate myocyte T‐tubule remodeling following myocardial infarction
Bi-Yi Chen, Yue Li, Shuxia Jiang, Yu-Ping Xie +7 more
2012The FASEB Journal78 citations Open access
Semantic Scholar
Sirtuin1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel
Ajit Vikram, Christopher M. Lewarchik, Jin-Young Yoon, Asma Naqvi +23 more
2017Nature Medicine72 citations Open access
Semantic Scholar
Molecular Determinants of Calpain-dependent Cleavage of Junctophilin-2 Protein in Cardiomyocytes*
A. Guo, Duane D. Hall, Caimei Zhang, T. Peng +6 more
2015Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Targeting Calpain for Heart Failure Therapy
Yi-Hui Wang, Bi-Yi Chen, Chun-kai Huang, A. Guo +10 more
2018JACC: Basic to Translational Science66 citations Open access
Semantic Scholar
Cardiac Sodium-Glucose Co-Transporter 1 (SGLT1) is a Novel Mediator of Ischemia/Reperfusion Injury.
Zhao Li, V. Agrawal, Mohun Ramratnam, Ravi K. Sharma +8 more
2019Cardiovascular Research64 citations Open access
Semantic Scholar
Differential activation of stress-response signaling in load-induced cardiac hypertrophy and failure.
B. Rothermel, K. Berenji, P. Tannous, W. Kutschke +8 more
2005Physiological Genomics62 citations Open access
Semantic Scholar
Genetic Inhibition of Na+-Ca2+ Exchanger Current Disables Fight or Flight Sinoatrial Node Activity Without Affecting Resting Heart Rate
Zhan Gao, Tyler P. Rasmussen, Yue Li, W. Kutschke +14 more
2012Circulation Research54 citations Open access
Semantic Scholar
Aortic valve sclerosis in mice deficient in endothelial nitric oxide synthase.
R. El-Accaoui, Sarah T. Gould, G. Hajj, Yi Chu +10 more
2014American Journal of Physiology. Heart and Circulatory Physiology53 citations Open access
Semantic Scholar
Effects of deep sedation or general anesthesia on cardiac function in mice undergoing cardiovascular magnetic resonance
Christopher J. Berry, D. Thedens, K. Light-McGroary, Jordan D. Miller +3 more
2009Journal of Cardiovascular Magnetic Resonance51 citations Open access
Semantic Scholar
Calcium/Calmodulin-Dependent Kinase II Inhibition in Smooth Muscle Reduces Angiotensin II–Induced Hypertension by Controlling Aortic Remodeling and Baroreceptor Function
A. Prasad, D. Morgan, D. Nuno, P. Ketsawatsomkron +10 more
2015Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease45 citations Open access
Semantic Scholar
Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity
S. Murthy, Olha M. Koval, Juan Ramiro Diaz, Santosh Kumar +10 more
2017PLoS ONE40 citations Open access
Semantic Scholar
Differential Control of Calcium Homeostasis and Vascular Reactivity by CaMKII
A. Prasad, D. Nuno, Olha M. Koval, P. Ketsawatsomkron +10 more
2013HYPERTENSION33 citations Open access
Semantic Scholar
A Novel Murine Model of Marfan Syndrome Accelerates Aortopathy and Cardiomyopathy
Nicholas B. Cavanaugh, Lan Qian, Nicole M. Westergaard, W. Kutschke +2 more
2017Annals of Thoracic Surgery28 citations Open access
Semantic Scholar
Vascular Actions of Peripheral CGRP in Migraine-Like Photophobia in Mice
Bianca N Mason, Anne-Sophie Wattiez, L. Balcziak, A. Kuburas +2 more
2020Cephalalgia26 citations Open access
Semantic Scholar
Sildenafil ameliorates left ventricular T-tubule remodeling in a pressure overload-induced murine heart failure model
Chun-kai Huang, Bi-Yi Chen, A. Guo, Rong Chen +4 more
2016Acta Pharmacologica Sinica25 citations Open access
Semantic Scholar
Microtubule-Mediated Defects in Junctophilin-2 Trafficking Contribute to Myocyte T-Tubule Remodeling and Ca 2 + Handling Dysfunction in Heart Failure
Caimei Zhang, Bi-Yi Chen, A. Guo, Yanqi Zhu +12 more
201425 citations
Semantic Scholar
In vivo measurement of intrauterine pressure by telemetry: a new approach for studying parturition in mouse models.
Stephanie L. Pierce, W. Kutschke, R. Cabeza, S. England
2010Physiological Genomics25 citations Open access
Semantic Scholar
MG53 is dispensable for T-tubule maturation but critical for maintaining T-tubule integrity following cardiac stress
Caimei Zhang, Bi-Yi Chen, Yi-Hui Wang, A. Guo +11 more
2017Journal of Molecular and Cellular Cardiology23 citations Open access
Semantic Scholar
Functional correction of short-chain acyl-CoA dehydrogenase deficiency in transgenic mice: implications for gene therapy of human mitochondrial enzyme deficiencies.
C. Kelly, W. Rhead, W. Kutschke, A. Brix +4 more
1997Human Molecular Genetics21 citations
Semantic Scholar
Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling.
Christian Riehle, E. Weatherford, A. Wende, Bharat P. Jaishy +15 more
2020JCI Insight20 citations Open access
Semantic Scholar
Superoxide scavenging and Akt inhibition in myocardium ameliorate pressure overload-induced NF-κB activation and cardiac hypertrophy.
S. Hingtgen, Zhenbo Li, W. Kutschke, Xin Tian +2 more
2010Physiological Genomics19 citations Open access
Semantic Scholar
FUNCTIONAL RESILIENCE OF C57BL/6J MOUSE HEART TO DIETARY FAT OVERLOAD.
S. M. Tadinada, E. Weatherford, Greg V Collins, Gourav Bhardwaj +7 more
2021American Journal of Physiology. Heart and Circulatory Physiology15 citations Open access
Semantic Scholar
Transient activation of PKC results in long-lasting detrimental effects on systolic [Ca2+]i in cardiomyocytes by altering actin cytoskeletal dynamics and T-tubule integrity
A. Guo, Rong Chen, Yi-Hui Wang, Chun-kai Huang +4 more
2018Journal of Molecular and Cellular Cardiology9 citations Open access
Semantic Scholar
Na 1-Ca 2 1 Exchanger Remodeling in Pressure Overload Cardiac Hypertrophy *
Zheng-Yi Wang, Bridgid Nolan, W. Kutschke, Joseph A. Hill
20014 citations
Semantic Scholar
SUMOylation of the cardiac sodium channel NaV1.5 modifies inward current and cardiac excitability
Jin-Young Yoon, A. Greiner, Julia S. Jacobs, Young-Rae Kim +8 more
2023Heart Rhythm3 citations Open access
Semantic Scholar
Abstract 271: Reduced Expression of the Cardiac Sodium Channel Nav1.5 Triggers Enhanced Fatty Acid Metabolism and Oxidative Stress
R. Boudreau, Xiaoming Zhang, J. McLendon, W. Kutschke +2 more
2019Circulation Research3 citations
Semantic Scholar
SUMOylation of the Cardiac Sodium Channel NaV1.5 Modifies Inward Current and Cardiac Excitability
Jin-Young Yoon, A. Greiner, Julia S. Jacobs, Young-Rae Kim +7 more
2022bioRxiv2 citations Open access
Semantic Scholar
Publisher Correction: Mitochondrial pyruvate carriers are required for myocardial stress adaptation
Yuan Zhang, Paul V. Taufalele, J. Cochran, Isabelle Robillard‐Frayne +26 more
2020Nature Metabolism2 citations Open access
Semantic Scholar
Acute effects of euglycemic‐hyperinsulinemia on myocardial contractility in male mice
S. M. Tadinada, Wojciech J. Grzesik, W. Kutschke, Robert M. Weiss +1 more
2022Physiological Reports1 citations Open access
Semantic Scholar

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