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K. Hotta · SciRah

Researcher profile · Semantic Scholar

K. Hotta

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K. Hotta — researcher profile on SciRah

h-index: 27
Works: 55
Citations: 2,627

Most-cited papers

Variations in the FTO gene are associated with severe obesity in the Japanese
K. Hotta, Y. Nakata, T. Matsuo, S. Kamohara +23 more
2008Journal of Human Genetics255 citations Open access
Semantic Scholar
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians
H. Li, T. Kilpeläinen, C. Liu, J. Zhu +61 more
2011Diabetologia222 citations Open access
Semantic Scholar
Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan
Takuya Kitamoto, Aya Kitamoto, M. Yoneda, H. Hyogo +10 more
2013Human Genetics209 citations Open access
Semantic Scholar
Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease
K. Hotta, M. Yoneda, H. Hyogo, H. Ochi +6 more
2010BMC Medical Genetics165 citations Open access
Semantic Scholar
Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population
K. Hotta, M. Nakamura, Takahiro Nakamura, T. Matsuo +27 more
2009Journal of Human Genetics141 citations
Semantic Scholar
Adipocytokine Orosomucoid Integrates Inflammatory and Metabolic Signals to Preserve Energy Homeostasis by Resolving Immoderate Inflammation*
Yun-Sok Lee, Jin Woo Choi, Injae Hwang, Joo-Won Lee +10 more
2010Journal of Biological Chemistry123 citations Open access
Semantic Scholar
Association between angiotensin II type 1 receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease
M. Yoneda, K. Hotta, Y. Nozaki, H. Endo +15 more
2009Liver international (Print)90 citations
Semantic Scholar
Serum Ferritin Is a Clinical Biomarker in Japanese Patients with Nonalcoholic Steatohepatitis (NASH) Independent of HFE Gene Mutation
M. Yoneda, Y. Nozaki, H. Endo, H. Mawatari +12 more
2010Digestive Diseases and Sciences80 citations
Semantic Scholar
Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits.
Aya Kitamoto, Takuya Kitamoto, Takahiro Nakamura, Yuji Ogawa +10 more
2014Endocrine journal78 citations Open access
Semantic Scholar
Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population
K. Hotta, Takuya Kitamoto, Aya Kitamoto, Seiho Mizusawa +26 more
2011Journal of Human Genetics77 citations Open access
Semantic Scholar
Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease.
Takuya Kitamoto, Aya Kitamoto, Yuji Ogawa, Y. Honda +6 more
2015Journal of Hepatology75 citations Open access
Semantic Scholar
Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)
M. Yoneda, K. Hotta, Y. Nozaki, H. Endo +17 more
2008BMC Gastroenterology75 citations Open access
Semantic Scholar
Characteristics of non‐obese non‐alcoholic fatty liver disease: Effect of genetic and environmental factors
Y. Honda, M. Yoneda, T. Kessoku, Yuji Ogawa +10 more
2016Hepatology Research68 citations
Semantic Scholar
Serum vaspin concentrations are closely related to insulin resistance, and rs77060950 at SERPINA12 genetically defines distinct group with higher serum levels in Japanese population.
Sanae Teshigawara, J. Wada, K. Hida, Atsuko Nakatsuka +12 more
2012Journal of Clinical Endocrinology and Metabolism67 citations Open access
Semantic Scholar
Gap‐Junctional Communication Is Required for Mitotic Clonal Expansion during Adipogenesis
Takahiro Yanagiya, Atsushi Tanabe, K. Hotta
2007Obesity55 citations
Semantic Scholar
INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese
K. Hotta, M. Nakamura, Y. Nakata, T. Matsuo +24 more
2008Journal of Human Genetics53 citations Open access
Semantic Scholar
PPARG Genotype Accounts for Part of Individual Variation in Body Weight Reduction in Response to Calorie Restriction
T. Matsuo, Y. Nakata, Yasutomi Katayama, M. Iemitsu +6 more
2009Obesity51 citations Open access
Semantic Scholar
Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
Takahiro Yanagiya, Atsushi Tanabe, A. Iida, S. Saito +29 more
2007Human Molecular Genetics51 citations Open access
Semantic Scholar
Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
Atsushi Tanabe, Takahiro Yanagiya, A. Iida, S. Saito +26 more
2007Journal of Clinical Endocrinology and Metabolism47 citations
Semantic Scholar
Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.
K. Hotta, M. Hosaka, Atsushi Tanabe, T. Takeuchi
2009Journal of Endocrinology46 citations Open access
Semantic Scholar
FTO gene variant and risk of hypertension: a meta-analysis of 57,464 hypertensive cases and 41,256 controls.
Danhua He, Mao-Sun Fu, Song Miao, K. Hotta +2 more
2014Metabolism: Clinical and Experimental43 citations
Semantic Scholar
Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women
K. Hotta, Aya Kitamoto, Takuya Kitamoto, Seiho Mizusawa +31 more
2011Journal of Human Genetics43 citations Open access
Semantic Scholar
Identification of the genomic region under epigenetic regulation during non‐alcoholic fatty liver disease progression
K. Hotta, Takuya Kitamoto, Aya Kitamoto, Yuji Ogawa +7 more
2018Hepatology Research42 citations
Semantic Scholar
Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population
K. Hotta, M. Nakamura, Takahiro Nakamura, T. Matsuo +27 more
2010Journal of Human Genetics42 citations
Semantic Scholar
Identification of differentially methylated region (DMR) networks associated with progression of nonalcoholic fatty liver disease
K. Hotta, Aya Kitamoto, Takuya Kitamoto, Yuji Ogawa +7 more
2018Scientific Reports36 citations Open access
Semantic Scholar
Gene expression profiling of non‐alcoholic steatohepatitis using gene set enrichment analysis
M. Yoneda, H. Endo, H. Mawatari, Y. Nozaki +20 more
2008Hepatology Research36 citations
Semantic Scholar
Influence of inducible nitric oxide synthase polymorphisms in Japanese patients with non‐alcoholic fatty liver disease
M. Yoneda, K. Hotta, Y. Nozaki, H. Endo +16 more
2009Hepatology Research28 citations
Semantic Scholar
Effects of FTO Genotype on Weight Loss and Metabolic Risk Factors in Response to Calorie Restriction Among Japanese Women
T. Matsuo, Y. Nakata, Yukako Murotake, K. Hotta +1 more
2012Obesity27 citations Open access
Semantic Scholar
Identification of core gene networks and hub genes associated with progression of non‐alcoholic fatty liver disease by RNA sequencing
K. Hotta, M. Kikuchi, Takuya Kitamoto, Aya Kitamoto +11 more
2017Hepatology Research26 citations
Semantic Scholar
Influence of the rs738409 polymorphism in patatin‐like phospholipase 3 on the treatment efficacy of non‐alcoholic fatty liver disease with type 2 diabetes mellitus
Hiromi Kan, H. Hyogo, H. Ochi, K. Hotta +11 more
2016Hepatology Research23 citations Open access
Semantic Scholar
The FTO genotype as a useful predictor of body weight maintenance: initial data from a 5-year follow-up study.
T. Matsuo, Y. Nakata, K. Hotta, Kiyoji Tanaka
2014Metabolism: Clinical and Experimental23 citations Open access
Semantic Scholar
NUDT3 rs206936 is associated with body mass index in obese Japanese women.
Aya Kitamoto, Takuya Kitamoto, Seiho Mizusawa, H. Teranishi +31 more
2013Endocrine journal23 citations Open access
Semantic Scholar
Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography
K. Hotta, Aya Kitamoto, Takuya Kitamoto, Seiho Mizusawa +32 more
2012Journal of Human Genetics23 citations Open access
Semantic Scholar
Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area
K. Hotta, Takuya Kitamoto, Aya Kitamoto, Seiho Mizusawa +29 more
2011Journal of Human Genetics23 citations Open access
Semantic Scholar
CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.
Aya Kitamoto, Takuya Kitamoto, Takahiro Nakamura, T. Matsuo +25 more
2016Journal of atherosclerosis and thrombosis22 citations Open access
Semantic Scholar
Associations of obesity susceptibility loci with hypertension in Chinese children
B. Xi, X. Zhao, Y. Shen, L. Wu +5 more
2013International Journal of Obesity22 citations Open access
Semantic Scholar
Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease
Takuya Kitamoto, Aya Kitamoto, M. Yoneda, H. Hyogo +8 more
2014Journal of Human Genetics19 citations Open access
Semantic Scholar
Replication study of 15 recently published Loci for body fat distribution in the Japanese population.
K. Hotta, Aya Kitamoto, Takuya Kitamoto, Seiho Mizusawa +30 more
2013Journal of atherosclerosis and thrombosis18 citations Open access
Semantic Scholar
Life style-related diseases of the digestive system: gene expression in nonalcoholic steatohepatitis patients and treatment strategies.
M. Yoneda, H. Endo, Y. Nozaki, A. Tomimoto +12 more
2007Journal of Pharmacological Sciences17 citations Open access
Semantic Scholar
A novel compound heterozygous mutation in TTC8 identified in a Japanese patient
Shigeru Sato, T. Morimoto, K. Hotta, T. Fujikado +1 more
2019Human Genome Variation13 citations Open access
Semantic Scholar
Mutation in Bombesin Receptor Subtype-3 Gene is not a Major Cause of Obesity in the Japanese
K. Hotta, Y. Matsukawa, M. Nishida, K. Kotani +7 more
2000Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme13 citations
Semantic Scholar
Association of protein tyrosine phosphatase 1B gene polymorphism with the effects of weight reduction therapy on bodyweight and glycolipid profiles in obese patients
H. Yamakage, Yousuke Konishi, Kazuya Muranaka, K. Hotta +4 more
2021Journal of Diabetes Investigation11 citations Open access
Semantic Scholar
ADIPOQ polymorphisms are associated with insulin resistance in Japanese women.
Aya Kitamoto, Takuya Kitamoto, R. So, T. Matsuo +26 more
2015Endocrine journal11 citations Open access
Semantic Scholar
Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick–Kaufman syndrome gene variants are associated with metabolic syndrome
K. Hotta, Takahiro Nakamura, Junichi Takasaki, Hiroshi Takahashi +25 more
2009Journal of Human Genetics7 citations
Semantic Scholar
Two differentially methylated region networks in nonalcoholic fatty liver disease, viral hepatitis, and hepatocellular carcinoma
Suguru Kurokawa, M. Yoneda, Yuji Ogawa, Y. Honda +5 more
2022BMC Gastroenterology4 citations Open access
Semantic Scholar
Eleven-year follow-up of a Japanese retinitis pigmentosa patient with an HK1 gene mutation
Shigeru Sato, T. Morimoto, K. Hotta, T. Fujikado +1 more
2019Ophthalmic Genetics4 citations
Semantic Scholar
Novel mutation identified in Leber congenital amaurosis - a case report
Shigeru Sato, T. Morimoto, Sayaka Tanaka, K. Hotta +3 more
2020BMC Ophthalmology3 citations Open access
Semantic Scholar
[New insights about obesity-related genes].
K. Hotta
2009Nihon rinsho. Japanese journal of clinical medicine2 citations
Semantic Scholar
[New insight of genome-wide association study (GWAS)].
K. Hotta
2013Nihon rinsho. Japanese journal of clinical medicine1 citations
Semantic Scholar
Title Association of the rs 738409 polymorphism in PNPLA 3 with liver damage and the development of nonalcoholic fatty liver disease
K. Hotta, M. Yoneda, H. Hyogo, H. Ochi +6 more
20180 citations
Semantic Scholar

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