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Meng-Meng Ning · SciRah

Researcher profile · Semantic Scholar

Meng-Meng Ning

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Meng-Meng Ning — researcher profile on SciRah

h-index: 14
Works: 31
Citations: 682

Most-cited papers

Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.
Hongliang Duan, Meng-Meng Ning, Qing-An Zou, Yang-liang Ye +4 more
2015Journal of Medicinal Chemistry84 citations Open access
Semantic Scholar
Design, synthesis, and antidiabetic activity of 4-phenoxynicotinamide and 4-phenoxypyrimidine-5-carboxamide derivatives as potent and orally efficacious TGR5 agonists.
Hongliang Duan, Meng-Meng Ning, Xiaoyan Chen, Qing-An Zou +5 more
2012Journal of Medicinal Chemistry81 citations Open access
Semantic Scholar
TGR5 agonist ameliorates insulin resistance in the skeletal muscles and improves glucose homeostasis in diabetic mice.
Su-Ling Huang, Sha Ma, Meng-Meng Ning, Wen-ji Yang +4 more
2019Metabolism: Clinical and Experimental61 citations
Semantic Scholar
Intestinally-targeted TGR5 agonists equipped with quaternary ammonium have an improved hypoglycemic effect and reduced gallbladder filling effect
Hua Cao, Zhi-Xiang Chen, Kai Wang, Meng-Meng Ning +5 more
2016Scientific Reports54 citations Open access
Semantic Scholar
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RARα-PPARγ-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice
Zhuo-Hui Zhao, Zhen-Tao Deng, Su-Ling Huang, Meng-Meng Ning +4 more
2022Nutrients45 citations Open access
Semantic Scholar
Emodin, an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, regulates adipocyte function in vitro and exerts anti-diabetic effect in ob/ob mice
Yuejiao Wang, Su-Ling Huang, Ying Feng, Meng-Meng Ning +1 more
2012Acta Pharmacologica Sinica45 citations Open access
Semantic Scholar
Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators.
Wei-Wei Mao, Meng-Meng Ning, Zhi-Qing Liu, Qingzhang Zhu +2 more
2012Bioorganic & Medicinal Chemistry43 citations Open access
Semantic Scholar
Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2
Meng-Meng Ning, Wen-ji Yang, Wei-Bin Guan, Yi-pei Gu +2 more
2020Acta Pharmacologica Sinica38 citations Open access
Semantic Scholar
4-Benzofuranyloxynicotinamide derivatives are novel potent and orally available TGR5 agonists.
Qing-An Zou, Hongliang Duan, Meng-Meng Ning, Jia Liu +5 more
2014European journal of medicinal chemistry32 citations Open access
Semantic Scholar
Discovery of Highly Potent and Selective Thyroid Hormone Receptor β Agonists for the Treatment of Nonalcoholic Steatohepatitis.
Liuyu Hu, Yi-pei Gu, Junzhi Liang, Meng-Meng Ning +6 more
2023Journal of Medicinal Chemistry31 citations Open access
Semantic Scholar
Design, Synthesis, and Structure–Activity Relationships of 3,4,5‐Trisubstituted 4,5‐Dihydro‐1,2,4‐oxadiazoles as TGR5 Agonists
Jun-Jie Zhu, Yang-liang Ye, Meng-Meng Ning, A. Mándi +5 more
2013ChemMedChem29 citations Open access
Semantic Scholar
OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition
Sha Ma, Meng-Meng Ning, Qing-An Zou, Ying Feng +3 more
2016Acta Pharmacologica Sinica26 citations Open access
Semantic Scholar
MiR-146a alleviates inflammatory bowel disease in mice through systematic regulation of multiple genetic networks
Feng-Ting Zhu, Tao Yang, Meng-Meng Ning, Yang Liu +13 more
2024Frontiers in Immunology23 citations Open access
Semantic Scholar
Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold.
Jun-Jie Zhu, Meng-Meng Ning, Cen Guo, Li-Na Zhang +3 more
2013European journal of medicinal chemistry15 citations Open access
Semantic Scholar
Yhhu4488, a novel GPR40 agonist, promotes GLP-1 secretion and exerts anti-diabetic effect in rodent models.
Dan-Yang Guo, De-Wen Li, Meng-Meng Ning, Xiang-yu Dang +4 more
2015Biochemical and Biophysical Research Communications - BBRC14 citations
Semantic Scholar
Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects.
Fanghui Han, Meng-Meng Ning, Hua Cao, Yang-liang Ye +3 more
2020European journal of medicinal chemistry12 citations Open access
Semantic Scholar
Metabolomic Study of High-Fat Diet-Induced Obese (DIO) and DIO Plus CCl4-Induced NASH Mice and the Effect of Obeticholic Acid
Nanlin Zhu, Su-Ling Huang, Qingli Zhang, Zhuo-Hui Zhao +4 more
2021Metabolites9 citations Open access
Semantic Scholar
Design and exploration of gut-restricted bifunctional molecule with TGR5 agonistic and DPP4 inhibitory effects for treating ulcerative colitis.
Fanghui Han, Meng-Meng Ning, Kai Wang, Yi-pei Gu +3 more
2022European journal of medicinal chemistry7 citations Open access
Semantic Scholar
Design, synthesis and structure−activity relationship studies of GPR40 agonists containing amide linker
Ting-Ting Chen, Meng-Meng Ning, Yang-liang Ye, Kai Wang +2 more
20187 citations Open access
Semantic Scholar
Synthesis and evaluation of piperidine urea derivatives as efficacious 11β-hydroxysteroid dehydrogenase type 1 inhibitors in diabetic ob/ob mice.
Li-Ming Zhang, Jun-Hua Chen, Meng-Meng Ning, Qing-An Zou +2 more
2012Bioorganic & Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
Investigation on the oxidation of aryl oxiranylmethanols and the synthesis of 2-aryl-N-thiazolyl-oxirane-2-carboxamides as glucokinase activators
Na Ye, Xiang-Jun Xu, Fu-Ying Li, Meng-Meng Ning +4 more
20127 citations
Semantic Scholar
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio.
Xuehang Tang, Meng-Meng Ning, Yang-liang Ye, Yi-pei Gu +3 more
2021Bioorganic & Medicinal Chemistry6 citations Open access
Semantic Scholar
Discovery and Structure-Activity Relationship Study of 4-Phenoxythiazol-5-carboxamides as Highly Potent TGR5 Agonists.
Zhi-Xiang Chen, Meng-Meng Ning, Qing-An Zou, Hua Cao +3 more
2016Chemical and pharmaceutical bulletin5 citations Open access
Semantic Scholar
Discovery of Highly Polar β-homophenylalanine Derivatives as Non-systemic Intestine-Targeted Dipeptidyl Peptidase IV Inhibitors.
Fu-Bao Huang, Meng-Meng Ning, Kai Wang, Jia Liu +3 more
2019Journal of Medicinal Chemistry2 citations Open access
Semantic Scholar
副作用を低減した新しい低吸収TGR5作動薬,OL3はTGR5活性化とDPP‐4阻害に対する二重作用を介して血中グルコースを低下させる【Powered by NICT】
Sha Ma, Meng-Meng Ning, Qing-An Zou, Ying Feng +3 more
20160 citations
Semantic Scholar
Corrigendum: Design, Synthesis, and Structure–Activity Relationships of 3,4,5‐Trisubstituted 4,5‐Dihydro‐1,2,4‐oxadiazoles as TGR5 Agonists
Jun-Jie Zhu, Yang-liang Ye, Meng-Meng Ning, A. Mándi +5 more
20150 citations Open access
Semantic Scholar
浅谈“十二生肖”图形在儿童语音闹钟上的应用
Ting-Ting Cai, Meng-Meng Ning
20150 citations
Semantic Scholar
Amide compounds and preparation methods, pharmaceutical compositions and uses thereof
Jia-Ni Shen, Y. Leng, Qing Zou, Meng-Meng Ning
20130 citations
Semantic Scholar
一种含氮杂环链接的苯丙酸类化合物、其药物组合物、制备方法和用途
You-hong Hu, Y. Leng, De-Wen Li, Meng-Meng Ning
20130 citations
Semantic Scholar
Five yuan heterocyclic azole compounds and its preparation method, pharmaceutical compositions and uses
Jia-Ni Shen, Y. Leng, Jun-Jie Zhu, Meng-Meng Ning
20120 citations
Semantic Scholar
Aroxylpyrimidine formamide or aroxylpyridine formamide compound and its preparation method, pharmaceutical composition, and application
Y. Leng, Jia-Ni Shen, Hongliang Duan, Meng-Meng Ning
20110 citations
Semantic Scholar

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