Researcher profile · Semantic Scholar

Dawid Jaślan

h-index: 9
Works: 26
Citations: 252

Most-cited papers

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann–Pick type C1, and Batten disease
Anna Scotto-Rosato, E. Krogsaeter, Dawid Jaślan, C. Abrahamian +26 more
2022EMBO Molecular Medicine43 citations Open access
Semantic Scholar
Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes
Yu Yuan, Dawid Jaślan, Taufiq Rahman, S. Bolsover +12 more
2022Nature Communications36 citations Open access
Semantic Scholar
Evolutionary Aspects of TRPMLs and TPCs
Dawid Jaślan, Julia Böck, E. Krogsaeter, C. Grimm
2020International Journal of Molecular Sciences29 citations Open access
Semantic Scholar
Neurodegenerative Lysosomal Storage Disorders: TPC2 Comes to the Rescue!
Sandra Prat Castro, Veronika Kudrina, Dawid Jaślan, Julia Böck +2 more
2022Cells25 citations Open access
Semantic Scholar
TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P
Meng-Nan Xu, X. Zhong, Peng Huang, Dawid Jaślan +6 more
2023Proceedings of the National Academy of Sciences of the United States of America18 citations Open access
Semantic Scholar
OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage
Volodymyr Tsvilovskyy, R. Ottenheijm, U. Kriebs, Aline Schütz +36 more
2024Journal of Clinical Investigation17 citations Open access
Semantic Scholar
Electrophysiology of Endolysosomal Two-Pore Channels: A Current Account
Sandip Patel, Yu Yuan, Cheng-Chang Chen, Dawid Jaślan +4 more
2022Cells13 citations Open access
Semantic Scholar
Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist
Gamma Chi, Dawid Jaślan, Veronika Kudrina, Julia Böck +14 more
2024Structure12 citations Open access
Semantic Scholar
Lysosomal TMEM165 controls cellular ion homeostasis and survival by mediating lysosomal Ca2+ import and H+ efflux
Ran Chen, Bin Liu, Dawid Jaślan, Lucija Kucej +8 more
2025Nature Communications11 citations Open access
Semantic Scholar
TPCs: From plant to human.
Yvonne E. Klingl, Arnas Petrauskas, Dawid Jaślan, Christian M. Grimm
2025Physiological Reviews8 citations
Semantic Scholar
PI(3,5)P2 and NAADP: Team players or lone warriors? - New insights into TPC activation modes.
Dawid Jaślan, Irene Ferro, Veronika Kudrina, Yu Yuan +2 more
2022Cell Calcium8 citations
Semantic Scholar
Sugar beet PMT5a and STP13 carriers suitable for proton-driven plasma membrane sucrose and glucose import in taproots.
Antonella Reyer, Nadia Bazihizina, Justyna Jaślan, S. Scherzer +8 more
2024The Plant Journal7 citations Open access
Semantic Scholar
TMEM165 replenishes lysosomal Ca2+ stores, protects cells against Ca2+ overload, and mediates Ca2+-induced lysosomal H+ leakage
Ran Chen, Bin Liu, Dawid Jaślan, Lucija Kucej +7 more
2024bioRxiv5 citations Open access
Semantic Scholar
TRPML1 suppresses pulmonary fibrosis by limiting collagen and elastin deposition
Eva-Maria Weiden, Zala Serianz, Yvonne E. Klingl, S. Jörs +26 more
2026EMBO Journal4 citations Open access
Semantic Scholar
Coordinating activation of endo‐lysosomal two‐pore channels and TRP mucolipins
Yu Yuan, Dawid Jaślan, Taufiq Rahman, F. Bracher +2 more
2024Journal of Physiology4 citations Open access
Semantic Scholar
New insights into gating mechanisms in TPCs: Relevance for drug discovery.
Dawid Jaślan, Sandip Patel, C. Grimm
2023Cell Calcium4 citations Open access
Semantic Scholar
TRPML2 in distinct states reveals the activation and modulation principles of the TRPML family
P. Schmiege, Dawid Jaślan, M. Fine, Nidish Ponath Sadanandan +4 more
2025Nature Communications2 citations Open access
Semantic Scholar
Vicia faba SV channel VfTPC1 is a hyperexcitable variant of plant vacuole Two Pore Channels
Jinping Lu, I. Dreyer, M. Dickinson, S. Panzer +8 more
2023eLife2 citations Open access
Semantic Scholar
Regulation of Ferroptosis Sensitivity in Hepatocellular Carcinoma Cells by Lysosomal Ion Channels TPC2 and TRPML1
Franz Geisslinger, V. Gell, Finja Witt, Dawid Jaślan +3 more
2026Antioxidants1 citations Open access
Semantic Scholar
PLASTID ENVELOPE ION CHANNELS (PEC1/2) link Ca2+ and jasmonic acid signaling in plant cells
Susanne Mühlbauer, Dawid Jaślan, Inês F. Duarte Nunes, Benjamin Brandt +13 more
2026Proceedings of the National Academy of Sciences of the United States of America1 citations Open access
Semantic Scholar
Beet taproot plasma membrane sugar transport revisited
Antonella Reyer, Nadia Bazihizina, S. Scherzer, Justyna Jaślan +15 more
2021bioRxiv1 citations Open access
Semantic Scholar
Vicia faba TPC1, a genetically encoded variant of the vacuole Two Pore Channel 1, is hyperexcitable
Jinping Lu, I. Dreyer, M. Dickinson, S. Panzer +8 more
2021bioRxiv1 citations Open access
Semantic Scholar
BPS2026 - Structural and functional characterization of TPC2 modulation and a novel gain-of-function mutation in TPC1
Rebecca Ulrike Susanna Marie Deutsch, D. Menegaz, Benedikt Mayer, C. Ziegler +6 more
2026Biophysical Journal0 citations
Semantic Scholar
Allosteric switching of Ca2+ permeability in the lysosomal ion channel TPC2 underpins biased agonist activation
Qian-Ru Mu, Ryo Saito, Franceska Ozola, Dawid Jaślan +16 more
2026EMBO Journal0 citations Open access
Semantic Scholar
TPC1-dependent control of endosomal pH and transferrin uptake determines cellular iron status
Rebecca Deutsch, S. Jörs, Yvonne E. Klingl, Veronika Kudrina +22 more
2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
TPC1 in plants
C. Grimm, Dawid Jaślan
20200 citations
Semantic Scholar

Yu Yuan×5

F. Bracher×5

I. Marten×4