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A. Flenniken · SciRah

Researcher profile · Semantic Scholar

A. Flenniken

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A. Flenniken — researcher profile on SciRah

h-index: 31
Works: 76
Citations: 5,224

Most-cited papers

High-throughput discovery of novel developmental phenotypes
M. Dickinson, A. Flenniken, Xiao Ji, L. Teboul +80 more
2016Nature1,115 citations Open access
Semantic Scholar
Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.
N. Gale, S. Holland, D. Valenzuela, A. Flenniken +9 more
1996Neuron896 citations Open access
Semantic Scholar
A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia
A. Flenniken, L. Osborne, Nicole Anderson, N. Ciliberti +31 more
2005Development248 citations
Semantic Scholar
Prevalence of sexual dimorphism in mammalian phenotypic traits
N. Karp, Jeremy C. Mason, A. Beaudet, Y. Benjamini +39 more
2017Nature Communications243 citations Open access
Semantic Scholar
Disease Model Discovery from 3,328 Gene Knockouts by The International Mouse Phenotyping Consortium
T. Meehan, N. Conte, David B. West, Julius O. B. Jacobsen +59 more
2017Nature Genetics235 citations Open access
Semantic Scholar
A lymphatic defect causes ocular hypertension and glaucoma in mice.
Benjamin R. Thomson, S. Heinen, M. Jeansson, A. Ghosh +13 more
2014Journal of Clinical Investigation161 citations Open access
Semantic Scholar
Analysis of mammalian gene function through broad based phenotypic screens across a consortium of mouse clinics
M. D. de Angelis, G. Nicholson, M. Selloum, Jacqueline K. White +165 more
2015Nature Genetics155 citations Open access
Semantic Scholar
Segmental expression of the EphA4 (Sek-1) receptor tyrosine kinase in the hindbrain is under direct transcriptional control of Krox-20.
T. Theil, M. Frain, P. Gilardi-Hebenstreit, A. Flenniken +2 more
1998Development152 citations
Semantic Scholar
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction
M. Bowl, M. Simon, N. Ingham, Simon Greenaway +197 more
2017Nature Communications144 citations Open access
Semantic Scholar
Anatomical phenotyping in the brain and skull of a mutant mouse by magnetic resonance imaging and computed tomography.
B. Nieman, A. Flenniken, S. Adamson, R. Henkelman +1 more
2006Physiological Genomics130 citations
Semantic Scholar
Expression of the Wilms' tumor suppressor gene WT1 during mouse embryogenesis.
R. Rackley, A. Flenniken, Nishi P. Kuriyan, Patricia M. Kessler +2 more
1993Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research123 citations
Semantic Scholar
Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells.
W. Breitwieser, S. Lyons, A. Flenniken, G. Ashton +5 more
2007Genes & Development110 citations Open access
Semantic Scholar
The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation
V. Muñoz-Fuentes, Pilar Cacheiro, T. Meehan, J. A. Aguilar-Pimentel +20 more
2018Conservation Genetics103 citations Open access
Semantic Scholar
Identification of a serum- and phorbol ester-responsive element in the murine tissue inhibitor of metalloproteinase gene.
Christine E. Campbell, A. Flenniken, D. Skup, Bryan R. G. Williams
1991Journal of Biological Chemistry97 citations
Semantic Scholar
Applying the ARRIVE Guidelines to an In Vivo Database
N. Karp, T. Meehan, Hugh Morgan, Jeremy C. Mason +26 more
2015PLoS Biology92 citations Open access
Semantic Scholar
Human and mouse essentiality screens as a resource for disease gene discovery
Pilar Cacheiro, V. Muñoz-Fuentes, S. Murray, M. Dickinson +41 more
2020Nature Communications90 citations Open access
Semantic Scholar
Roles of Eph receptors and ephrins in neural crest pathfinding
V. Robinson, Alexa Smith, A. Flenniken, D. Wilkinson
1997Cell and Tissue Research87 citations
Semantic Scholar
Developmental expression of the endogenous TIMP gene and a TIMP-lacZ fusion gene in transgenic mice.
A. Flenniken, Bryan R. G. Williams
1990Genes & Development81 citations Open access
Semantic Scholar
The Sweet Pee model for Sglt2 mutation.
Joseph P. Ly, T. Onay, Karen Sison, Gavasker A. Sivaskandarajah +11 more
2011Journal of the American Society of Nephrology77 citations Open access
Semantic Scholar
First Mouse Model for Combined Osteogenesis Imperfecta and Ehlers‐Danlos Syndrome
Frieda Chen, Ruo-Lin Guo, Shousaku Itoh, Luisa Moreno +11 more
2014Journal of Bone and Mineral Research75 citations Open access
Semantic Scholar
Identification of genetic elements in metabolism by high-throughput mouse phenotyping
J. Rozman, B. Rathkolb, Manuela A. Oestereicher, C. Schütt +262 more
2018Nature Communications69 citations Open access
Semantic Scholar
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy
N. Spielmann, Gregor Miller, Tudor I. Oprea, Chih-Wei Hsu +243 more
2022Nature Cardiovascular Research55 citations Open access
Semantic Scholar
A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium
D. Barupal, Ying Zhang, Tong Shen, S. Fan +18 more
2019bioRxiv51 citations Open access
Semantic Scholar
The V–ATPase a3 subunit mutation R740S is dominant negative and results in osteopetrosis in mice
Noelle Ochotny, A. Flenniken, Celeste Owen, I. Voronov +7 more
2011Journal of Bone and Mineral Research47 citations Open access
Semantic Scholar
Cage-lid hanging behavior as a translationally relevant measure of pain in mice
Han-Tao Zhang, Irene Lecker, Chereen Collymore, A. Dokova +27 more
2020Pain45 citations Open access
Semantic Scholar
Identification of genes required for eye development by high-throughput screening of mouse knockouts
B. Moore, B. Leonard, L. Sebbag, Sydney G. Edwards +65 more
2018Communications Biology40 citations Open access
Semantic Scholar
Coordinate expression of Wilms' tumor genes correlates with Wilms' tumor phenotypes.
H. Yeger, C. Cullinane, A. Flenniken, S. Chilton-MacNeil +6 more
1992Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research39 citations
Semantic Scholar
Expression of interferon-induced genes in different tissues of mice
A. Flenniken, J. Galabru, M. Rutherford, A. Hovanessian +1 more
1988Journal of Virology37 citations Open access
Semantic Scholar
The Deep Genome Project
K. C. Kent Lloyd, D. Adams, Gareth Baynam, A. Beaudet +40 more
2020Genome Biology35 citations Open access
Semantic Scholar
ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice
L. Kelsey, A. Flenniken, Da-Wei Qu, Alister P. W. Funnell +21 more
2013PLoS Genetics35 citations Open access
Semantic Scholar
Localization of TIMP in cycling mouse hair.
T. Kawabe, T. Rea, A. Flenniken, Bryan R. G. Williams +2 more
1991Development32 citations
Semantic Scholar
A novel ENU-generated truncation mutation lacking the spectrin-binding and C-terminal regulatory domains of Ank1 models severe hemolytic hereditary spherocytosis
M. Hughes, Nicole Anderson, S. Maltby, J. Wong +15 more
2010Experimental Hematology30 citations Open access
Semantic Scholar
The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling
S. Mai, K. Wei, A. Flenniken, S. L. Adamson +3 more
2010Developmental Dynamics29 citations Open access
Semantic Scholar
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density
A. Swan, C. Schütt, J. Rozman, Maria del Mar Muñiz Moreno +60 more
2020PLoS Genetics28 citations Open access
Semantic Scholar
Efficient Germline Transmission of Mouse Embryonic Stem Cells Grown in Synthetic Serum in the Absence of a Fibroblast Feeder Layer
Christopher M. Ward, P. Stern, M. A. Willington, A. Flenniken
2002Laboratory Investigation27 citations Open access
Semantic Scholar
High-throughput discovery of genetic determinants of circadian misalignment
Tao Zhang, Pan-Cheng Xie, Yingying Dong, Zhi-Wei Liu +33 more
2020PLoS Genetics21 citations Open access
Semantic Scholar
A novel Phex mutation in a new mouse model of hypophosphatemic rickets
Celeste Owen, Frieda Chen, A. Flenniken, L. Osborne +4 more
2012Journal of Cellular Biochemistry18 citations
Semantic Scholar
Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice
Manuela A. Oestereicher, J. Wotton, S. Ayabe, G. Bouabout +47 more
2023Mammalian Genome15 citations Open access
Semantic Scholar
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development
Justin Chee, L. Lanoue, Dave A. Clary, Kendall Higgins +204 more
2023BMC Biology14 citations Open access
Semantic Scholar
Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen
J. Wotton, Emma Peterson, A. Flenniken, R. Bains +46 more
2021Pain12 citations Open access
Semantic Scholar
Cytopenia induction by 5-fluorouracil identifies thrombopoietic mutants in sensitized ENU mutagenesis screens
Nicole M. Anderson, Zorana Berberovic, Elizabeth Berndl, M. L. Bailey +10 more
2011Experimental Hematology12 citations Open access
Semantic Scholar
Mendelian gene identification through mouse embryo viability screening
Pilar Cacheiro, C. Westerberg, J. Mager, M. Dickinson +118 more
2022Genome Medicine11 citations Open access
Semantic Scholar
Soft windowing application to improve analysis of high-throughput phenotyping data
Hamed Haselimashhadi, Mason C. Jeremy, V. Muñoz-Fuentes, Federico López-Gómez +60 more
2019bioRxiv11 citations Open access
Semantic Scholar
Corrigendum: High-throughput discovery of novel developmental phenotypes
M. Dickinson, A. Flenniken, Xiao Ji, L. Teboul +77 more
2017Nature11 citations Open access
Semantic Scholar
Multiple reaction monitoring assays for large-scale quantitation of proteins from 20 mouse organs and tissues
Sarah A. Michaud, Helena Pětrošová, Nicholas J. T. Sinclair, Andrea L. Kinnear +13 more
2024Communications Biology9 citations Open access
Semantic Scholar
Co-expression of prepulse inhibition and Schizophrenia genes in the mouse and human brain
L. Garrett, D. Trümbach, Dong-Yup Lee, S. Mandillo +88 more
2024Neuroscience Applied9 citations Open access
Semantic Scholar
Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia
Geoffrey A. Wood, A. Flenniken, L. Osborne, Craig Fleming +7 more
2005Experimental Dermatology9 citations
Semantic Scholar
Regulation of TIMP gene expression in cell culture and during mouse embryogenesis.
A. Flenniken, C. Campbell, B. Williams
1992Matrix (Stuttgart, Germany). Supplement9 citations
Semantic Scholar
Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes
Kendall Higgins, B. Moore, Zorana Berberovic, H. Adissu +41 more
2022Scientific Reports7 citations Open access
Semantic Scholar
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma
Yassene Mohammed, Sarah A. Michaud, H. Pětrošová, Jun-Cong Yang +8 more
2021npj Systems Biology and Applications7 citations Open access
Semantic Scholar

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